A systematic review of the efficacy of gum chewing for the amelioration of postoperative ileus.

Abstract:

BACKGROUND:Recent trials have shown promising results for the efficacy of gum chewing for the amelioration of postoperative ileus. This finding could have a major clinical impact since gum chewing is relatively harmless and cheap while postoperative ileus has a significant impact on healthcare. METHODS:Systematic review and meta-analysis of randomized controlled trials comparing the efficacy of gum chewing after colorectal surgery to a standard control for the amelioration of postoperative ileus, expressed as time to flatus, time to defecation and overall hospital stay. RESULTS:Five randomized controlled trials with a total number of 158 patients were found. The studies were homogeneous and a meta-analysis was performed. The pooled weighted mean difference (WMD) of time to flatus was significantly shorter for the gum-chewing group (20 h with a 95% confidence interval (CI) of 13-27). The pooled WMD of time to defecation was significantly shorter (29 h, 95% CI of 19-39). There was a non-significant trend towards a shorter postoperative hospital stay (1.3 days shorter, 95% CI of 3.2 days shorter to 0.6 days longer). CONCLUSION:This meta-analysis shows a favorable effect of gum chewing on time to flatus and defecation but no significant effect on the hospital stay.

journal_name

Dig Surg

journal_title

Digestive surgery

authors

de Castro SM,van den Esschert JW,van Heek NT,Dalhuisen S,Koelemay MJ,Busch OR,Gouma DJ

doi

10.1159/000117822

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

39-45

issue

1

eissn

0253-4886

issn

1421-9883

pii

000117822

journal_volume

25

pub_type

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