Vancomycin use in patients requiring hemodialysis: a literature review.

Abstract:

:Vancomycin, a glycopeptide antibiotic, has remained a popular antimicrobial agent throughout the past five decades, and is often included in empiric antibiotic regimens. With gram-positive coverage, it has found a niche in the treatment of methicillin-resistant Staphylococcus aureus. Although vancomycin has been in existence for many years, questions remain regarding its use. New technologies and practice pattern changes have occurred over the years that altered vancomycin dosing in hemodialysis (HD) patients. Examples of these changes include increased resistance of many organisms, development of high flux HD filters, and reprocessing practices. This review provides a summary of the several concerns that exist in the dosing of vancomycin in HD patients today, and provides a summary table of intradialytic dosing regimens.

journal_name

Semin Dial

journal_title

Seminars in dialysis

authors

Pallotta KE,Manley HJ

doi

10.1111/j.1525-139X.2007.00333.x

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

63-70

issue

1

eissn

0894-0959

issn

1525-139X

pii

SDI333

journal_volume

21

pub_type

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