Early pregnancy lipid concentrations and spontaneous preterm birth.

Abstract:

OBJECTIVE:Women who deliver preterm infants may be at increased risk for cardiovascular disease, perhaps related to dyslipidemia. STUDY DESIGN:In a nested case control study of women with spontaneous preterm birth, cholesterol, high-density lipoprotein, low-density lipoprotein, and triglycerides were evaluated. Lipid concentrations and gestational changes, as well as risk for preterm birth, were evaluated in women who delivered <34 (n = 23), >or=34-<37 (n = 67), and >or=37 weeks (n = 199). RESULTS:High cholesterol or triglycerides or=34-<37 weeks, respectively. Overweight women who delivered <34 weeks had particularly elevated early pregnancy concentrations of cholesterol and low-density lipoprotein; lean women with moderate preterm birth had elevated triglycerides. There was a reduced triglyceride response in the first half of pregnancy among women who delivered <34 weeks. CONCLUSION:Our results indicate the presence of dyslipidemia in women with spontaneous preterm birth.

journal_name

Am J Obstet Gynecol

authors

Catov JM,Bodnar LM,Kip KE,Hubel C,Ness RB,Harger G,Roberts JM

doi

10.1016/j.ajog.2007.04.024

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

610.e1-7

issue

6

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(07)00545-5

journal_volume

197

pub_type

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