Abstract:
INTRODUCTION:Overweight and obesity present significant public health concerns because of the link with numerous chronic health conditions. During the last ten years, since the discovery of leptin, great advances were obtained in the characterization oh the hypothalamic mechanisms involved in the control of food intake and thermogenesis. DEVELOPMENT:This review will present some the most recent findings in this field. It will be focused on the actions of leptin and insulin in the hypothalamus and will explore the hypothesis that hypothalamic resistance to the action of these hormones may play a key role in the development of obesity. CONCLUSIONS:The physical activity is an important component on long-term weight control. The exercise markedly increased phosphorylation activity of several proteins involved in leptin and insulin signal transduction in the hypothalamus. Recently our laboratory showed that physical activity increase in sensitivity to leptin- and insulin-induced anorexia after enhances interleukin-6 production. These findings provide support for the hypothesis that the appetite-suppressive actions of exercise may be mediated by the hypothalamus.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Cintra DE,Ropelle ER,Pauli JRsubject
Has Abstractpub_date
2007-12-01 00:00:00pages
672-82issue
11eissn
0210-0010issn
1576-6578pii
rn2006612journal_volume
45pub_type
杂志文章,评审abstract:INTRODUCTION:In partial seizures, from a clinical point of view or even from electroencephalography characterization of post-ictal period can be difficult. The spectral and complex network analysis could lead to a more accurate definition of its limits, as well as to a great understanding of the seizures. PATIENTS AND...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2017-04-16 00:00:00
abstract:INTRODUCTION:The dysembryoplastic neuroepithelial tumors tend to occur in young patients, with partial complex partial seizures which is refractory to medical treatment. These are stable lesions, with defined histological features, specially with clinical data corroboration. CLINICAL CASES:The clinical, imagiological,...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
abstract::The assessment of memory functions related to medial temporal lobe has become one of the most important issues on current neuropsychology. On this communication, we review the results which our research group has achieved using two functional magnetic resonance Image procedures to assess memory function: Hometown wal...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:Apolipoprotein E (ApoE) gen has been found to confer risk for Alzheimer disease in every population studied. We are interested in analyzed the exonic variants and the promoter polymorphisms in our Canary population. SUBJECTS AND METHODS:By means of PCR RFLP analysis of DNA from patients (NINCS ADRDA criteri...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract:INTRODUCTION:Although subjective memory complaints are one of the most common causes behind visits to health services, there are hardly any validated instruments in Spanish for evaluating their magnitude. Since memory complaint questionnaires usually include items referring to attentional and executive aspects, it has ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2012-02-01 00:00:00
abstract:INTRODUCTION:The efficiency of Cambridge Cognitive Examination' (CAMCOG) is analyzed as a tool to detect dementias in epidemiological studies. PATIENTS AND METHODS:The data were obtained from subjects who enrolled the second phase on a door-to-door field epidemiological study. The tool used was the 'Cambridge Mental D...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1999-02-16 00:00:00
abstract:INTRODUCTION:Examination of the special bilingual student (5% of the bilingual student population of the USA) permits us to use not only (1) the statistical reports of the population coefficients and percentages), (2) measurements of progress or performance (age in years or grades of progress at school) and (3) the neu...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract:INTRODUCTION:Infection of the Central Nervous System by free living amebas is an unusual event, 344 cases have been reported to date. The disease becomes evident in two different clinical fashions: Primary Amebic Meningoencephalitis (PAM) caused by Naegleria fowleri and Granulomatous Amebic Encephalitis (GAE) induced b...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:INTRODUCTION:SPECT, EEG AND CT scan offer information with several pathophysiologic meanings. Their results vary with time and according to the vascular affected territory. OBJECTIVE:We wanted to study how the sensibility varies and the relationship with the clinic of SPECT, qEEG and CT scan in the acute, subacute and...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract:AIMS:We outline a proposal for the structural and functional features needed to develop a registry of dementias which can be used to collect standardised information that is both reliable and valid concerning cases of dementia in the specialised health care centres within a particular geographical area. DEVELOPMENT:Du...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2006-07-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:There are few epidemiological studies specifically directed towards finding the features of the adult epileptic population requiring hospital admission. We proposed to analyze these features in a consecutive series of patients admitted to our department with epilepsy and find the prevalence ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract:INTRODUCTION:Nonconvulsive status epilepticus (NCSE) of frontal origin is a form of partial status epilepticus which has rarely been well-documented. The inespecificity of the symptoms contribute frequently to its misinterpretation being the EEG the most useful tool to make an accurate diagnosis. CLINICAL CASE:We repo...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:INTRODUCTION:The impossibility of treating patients with sleep disorders adequately means that, as specialists, we have to look for new pharmacological treatments and for this reason we examined the information in the paper by Salin Pascual (1999) about the increase in deep sleep when olanzapine is used as an antipsych...
journal_title:Revista de neurologia
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:AIM:To estimate the prevalence of dementia in the population aged above 65 in the district of Mungialde, Vizcaya. SUBJECTS AND METHODS:We conducted a two-phase door-to-door populational study. The Minimental State Examination and the Pfeiffer questionnaire were used in the screening phase. The Clinical Dementia Rating...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2008-01-16 00:00:00
abstract::We have carried out an overall analysis of the diagnostic approach to generalized epileptic crises in children. It is emphasized that the clinical history is an essential factor in reaching the correct diagnosis. This is inevitably followed by a general and then a specifically neurological physical examination. Four p...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:1998-02-01 00:00:00
abstract::Different therapeutic models have been presented with which to treat the condition of attention deficit hyperactivity disorder (ADHD) and the scientific literature speaks of the benefits linked to multimodal approaches. The National Institute of Mental Health report grants combined treatments an essential role. Throug...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:To obtain better understanding of the neurophysiology of sleep and of depression, together with any relationship there might be between them. DEVELOPMENT:We review the mechanisms of action of the neurotransmitters involved in the sleep-waking cycle, and also the antidepressive drugs, concentrating on those ...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-16 00:00:00
abstract:INTRODUCTION:Meningioma is one of the most frequent tumours affecting the central nervous system, with an estimated incidence of between 15 and 20% of all brain tumours. They are generally benign and slow growing. Their appearing as a cerebral infarction is very rare. CASE REPORT:A right-handed 75-year-old female pati...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract:INTRODUCTION:The advance in the achievement of effective therapies for multiple sclerosis (MS), the definition of appropriate therapeutic windows and to establish better diagnostic and prognostic biomarkers have become a challenging task for both researchers and clinicians. Some pitfalls in clinical trials might be rel...
journal_title:Revista de neurologia
pub_type: 指南,杂志文章
doi:
更新日期:2012-01-16 00:00:00
abstract:INTRODUCTION:Temporal orientation is a component of most screening tests for diagnosing cognitive impairment. Correct temporal orientation involves activating both semantic information (concepts of the calendar date) and episodic information (remembering the current date). AIMS:The aim of this study was to assess the ...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2011-03-16 00:00:00
abstract::The neuropathology of haemorrhagic and hypoxic-ischaemic perinatal encephalopathies and their effect on the post-natal development of the brain, has been studied in children who survived with these lesions (for days, weeks, months and even years). Eventually some children developed neurological sequelae, including epi...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
abstract::Autism spectrum disorder (autism) is a highly prevalent and heterogeneous family of neurodevelopmental disorders of genetic origins with potentially devastating implications for child, family, health and educational systems. Despite advances in paper-and-pencil screening and in standardization of diagnostic procedures...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2015-02-25 00:00:00
abstract:TITLE:Facilitar el acceso a toda la informacion debe ser una obligacion para las revistas medicas. : ...
journal_title:Revista de neurologia
pub_type: 信件
doi:
更新日期:2018-02-16 00:00:00
abstract:INTRODUCTION:Progressive supranuclear palsy is a disease that normally presents only sporadically in adults and courses in a progressive, chronic manner. It is characterised by the presence of supranuclear ophthalmoplegia, postural instability, a Parkinsonian syndrome, pseudobulbar affect, cervical dystonia and cogniti...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract:INTRODUCTION:CLIPPERS syndrome (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids) is an inflammatory process of the central nervous system whose distinguishing features are the enhancing punctiform lesions in the brainstem that appear in the magnetic resonance images. Clinic...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2013-10-16 00:00:00
abstract::In order to evaluate the degree of neurological knowledge in a general practitioner (GP), and given the lack of a useful instrument with which to do so, we propose the drawing up of a neurological knowledge test which would give adequate psychometric guarantees. By using a broad-based sample of professionals working i...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::It was recently suggested that lacunar strokes presenting with headache may be due to large intracranial artery disease. From the stroke database of the Neurology department, Hospital Sta Maria, we retrieved all lacunar strokes who had investigations of the intracranial circulation. Forty seven of the 208 lacunar stro...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:INTRODUCTION:The new 2015 criteria for neuromyelitis optica spectrum disorders (NMOSD) have been recently incorporated in the study of different international cohorts. AIM:To describe clinical-radiological characteristics and prognostic factors in patients with NMOSD according to the 2015 criteria. PATIENTS AND METHO...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2017-09-01 00:00:00
abstract:INTRODUCTION:Acute vascular lesions limited to the midbrain can yield varied disturbances of eye movements. They are more often infarcts than hemorrhages. CLINICAL CASE:We present the case of a 49 year old, non-hypertensive man who presented with sudden onset of bilateral up and down gaze palsy. CT defined a unilatera...
journal_title:Revista de neurologia
pub_type: 杂志文章
doi:
更新日期:2000-02-16 00:00:00
abstract::Brainstem dysgenesis designates all those patients with congenital dysfunction of cranial nerves and muscle tone due to prenatal lesions or malformations of the brainstem. This generic term has the advantage over the eponyms Moebius 'expanded' or 'unrestricted', Robin, Cogan or Carey-Fineman-Ziter syndromes in that it...
journal_title:Revista de neurologia
pub_type: 杂志文章,评审
doi:
更新日期:2018-04-01 00:00:00