Abstract：
INTRODUCTION:Cervical cancer, the second most common malignancy in women worldwide, is almost invariably associated with infection by human papillomavirus (HPV). However, although many women are infected with high-risk types of HPV, only a subset of infected women will ever develop cervical cancer. Therefore, host genetic factor may play a role in cervical carcinogenesis. Several studies suggested that immunological components play a key role in the development of cervical cancer. Polymorphism in the IL-1RA gene was associated with various malignant diseases. Data are lacking for cervical cancer. MATERIALS AND METHODS:In a case-control study we analyzed the polymorphism of IL-1RA in 150 women with cervical cancer and 209 healthy controls. Genomic DNA fragments were amplified by PCR. RESULTS:There was a strong significantly protective association between heterozygous AB genotype and HPV 18 (OR = 0.11, 95% CI = 0.04-0.30, p = 0.0000000). Similarly this result was demonstrated, in combined AB + BB genotypes of IL-1RA with HPV 18 (OR = 0.12, 95% CI= 0.05-0.30, p = 0.0000000) and HPV type 16 + 18 (OR = 0.18,95% CI = 0.08-0.38, p = 0.000005). We found high protective significant association between heterozygous genotype AB with adenocarcinoma (OR = 0.19, 95% CI = 0.09-0.40, p = 0.0000002) as well. CONCLUSION:These findings therefore suggest that the IL1-RA polymorphism is associated with cervical cancer.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Tamandani DM,Sobti RC,Shekari M,Kaur S,Huria Adoi
10.1007/s00404-007-0504-4subject
Has Abstractpub_date
2008-06-01 00:00:00pages
527-33issue
6eissn
0932-0067issn
1432-0711journal_volume
277pub_type
杂志文章abstract：PURPOSE:Operative hysteroscopy procedure is extensively used for the treatment of intrauterine abnormalities that can potentially cause infertility. To date, there are little data addressing the effect of operative hysteroscopy that applies electrical current for excision and its subsequent effect on endometrial thickn...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3988-3
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:To evaluate the possibility of using maternal anthropometric measurements for prediction of low birth weight in developing and developed countries. METHODS:Bivariate diagnostic meta-analysis was performed with hierarchical summary receiver operating characteristic curves. Ten databases, i.e., PubMed, EMBASE, C...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,meta分析
doi：10.1007/s00404-015-3721-2
更新日期：2015-10-01 00:00:00
abstract：:We assessed the value of preoperative chest x-rays in gynecological patients. Abnormalities were noted in the chest x-rays of 10% of 1175 patients with genital or breast disorders. When the chest x-ray was abnormal, 48% of patients had no clinical features of intrathoracic disease. Abnormal chest x-ray results did not...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF00932085
更新日期：1988-01-01 00:00:00
abstract：INTRODUCTION:Pectopexy, a laparoscopic method for prolapse surgery, showed promising results in previous transient testing by this group. It was shown that a single suture, yielding an ultimate load of 35 N, was equivalent to continuous suturing. This was demonstrated in an in vitro cadaver study. This transient data w...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05117-9
更新日期：2019-05-01 00:00:00
abstract：:There is no cure currently available for HPV infections, although ablative and excisional treatments of some dysplasias often result in a clinical and virological cure. Effective control measures of HPV-associated cancers rely on the prevention at four different levels. Apart from sexual abstinence, primary prevention...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-013-3011-9
更新日期：2013-11-01 00:00:00
abstract：INTRODUCTION:The aim of the study was to evaluate the factors that may affect experienced pain during office hysteroscopy performed without anesthesia in an outpatient setting. MATERIALS AND METHODS:We enrolled the patients into six groups, differentiated by parity, menopausal status and type of the sheath that was us...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-012-2667-x
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:This study aimed to develop a valid and reliable tool for evaluation of sexual health assessment in infertile women. METHODS:This was a mixed exploratory study consisting of two phases. At phase one, we reviewed the existing instruments and interviewed 20 infertile women to generate an item pool. Then, the res...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05832-8
更新日期：2020-10-19 00:00:00
abstract：PURPOSE:Pentraxin 3 (PTX3) is a locally secreted, quicker responsive pro-inflammatory protein than C-reactive protein (CRP). We evaluated the value of PTX3 in the prediction of ovarian hyperstimulation syndrome (OHSS), a severe complication of in vitro fertilization (IVF). METHODS:This two-year prospective follow-up s...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05556-9
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:To revisit risk factors of major obstetric hemorrhage in a large obstetric center. STUDY DESIGN:A retrospective case control study was conducted based on institutional electronic database and blood bank registry of a single center, 2005-2014. The major obstetric hemorrhage event was defined as transfusion of ≥...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3725-y
更新日期：2015-10-01 00:00:00
abstract：PURPOSE:To evaluate intracytoplasmic sperm injection (ICSI) outcome of women over age 39 and to determine when to discourage such couples to undergo IVF using their own oocytes. METHODS:Four hundred ninety-five consecutive women (n=668 cycles) over age 39 were evaluated by year-by-year age increments to discriminate t...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1116-y
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVE:Aim of the study was to evaluate Evra use in adolescents and compare the outcome with adult users. METHODS:A total of 80 adolescents and 178 adults were followed-up at 1-, 3-, and 6-month interval with their compliance, satisfaction, cycle control, and adverse events being assessed. RESULTS:Compliance rate ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1368-6
更新日期：2011-03-01 00:00:00
abstract：PURPOSE:WHO sets 24 months as the ideal minimum interpregnancy interval (IPI) to minimize maternal and perinatal adverse outcomes. Some studies suggest that an interval longer than 59 months may affect these outcomes, but little is known about its influence on labor. The primary objective of this study was to compare t...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05347-x
更新日期：2019-12-01 00:00:00
abstract：:A 51-year-old woman presented with lumbar backache leading to the preoperative diagnosis of a right solid adnexal mass with calcification on computed tomographic scan. Histological examination revealed a right ovarian luteinized thecoma characterized by extensive calcification and metaplastic ossification. Osteoblasts...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-001-0282-3
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:To compare pregnancy outcomes following induction of labor with prostaglandins versus extra-amniotic balloon catheter indicated for term isolated oligohydramnios. STUDY DESIGN:Retrospective cohort study of all women who underwent induction of labor due to term isolated oligohydramnios at a university affilia...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05080-5
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to evaluate whether induction of breech delivery at term is feasible and safe for mother and child compared with spontaneous vaginal breech delivery. STUDY DESIGN:A total of 268 singleton term breech deliveries with an attempted vaginal delivery were identified in a single-center ret...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3853-4
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:To investigate the efficacy of wide local excision as a surgical treatment for early-stage vulvar melanomas. METHODS:Wide local excision with or without lymph node dissection was performed in three patients with stage I vulvar melanoma (American Joint Committee on Cancer classification, 1992). RESULTS:All thr...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-009-1134-9
更新日期：2010-02-01 00:00:00
abstract：PURPOSE:In spite of several policies aiming to decrease cesarean rates and related complications such as uterine rupture, data show that uterine rupture and associated morbidity are increasing along the years. Whether previously unidentified risk factors are currently playing an important role on these trends is unknow...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-017-4508-4
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:To assess changing trends, role of the triad patient-pregnancy-health professionals and health care cost in emergency peripartum hysterectomy (EPH). METHODS:Demographics, indications, perinatal outcomes, perioperative complications in EPH cases performed in a 10-year period were extracted from the local birth ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-020-05504-7
更新日期：2020-05-01 00:00:00
abstract：:Plasma and erythrocyte zinc concentrations in 45 proteinuric pre-eclamptic Chinese women were measured. There was no difference in either the plasma or erythrocyte zinc concentration between pre-eclamptic patients with and without intrauterine growth retardation. There was no correlation between either plasma or eryth...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF02389541
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:Transversus abdominis plane (TAP) block has been shown to provide pain relief after abdominal procedures. However, TAP block combined with multimodal analgesia technique have not been assessed in a randomized controlled trial. This randomized, controlled, observer-blinded study was designed to evaluate the a...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00404-012-2698-3
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:The aim of this study was to investigate the impact of bacterial vaginal flora on life-birth rate during ICSI and influence of metronidazole as antibiotic treatment course before ICSI. METHOD:We enrolled 71 women who were undergoing ICSI. At embryo transfer (ET), all of the women had quantitative vaginal cultu...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-011-1857-2
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVES:The influence a job--including its physical and psychological aspects--has on pregnant woman's chances of delivering prematurely. METHODS:Seven hundred and seven women who had given birth participated. Statements regarding her job and its stresses were obtained with a standardised questionnaire. RESULTS:Tw...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s00404-003-0487-8
更新日期：2003-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare a low-dose aspirin treatment on placental and perinatal effects in the patients with poor obstetric history such as preeclampsia, intrauterine growth retardation (IUGR) in previous pregnancy. STUDY DESIGN:This retrospective study of 86 pregnant women was conducted between...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章
doi：10.1007/s00404-006-0162-y
更新日期：2006-07-01 00:00:00
abstract：PURPOSE:In developed countries, around 25% of all births involve labour induction. Studies have indicated that labour induction negatively influences the birth experience as well as the birth process. However, the impact of labour induction when only considering vaginal deliveries has not been studied yet, which was th...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05150-8
更新日期：2019-07-01 00:00:00
abstract：:Intrauterine devices are a very effective form of contraception used worldwide for more than 2 centuries. One of the serious, but rare, complications of intrauterine contraception is perforation through the uterine wall into the pelvic or abdominal cavity. In this report we describe, persistent periumbilical discharge...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-007-0477-3
更新日期：2008-05-01 00:00:00
abstract：:We used a combination of 4 monoclonal antibodies (BM7, BM8 against MUC1, 5D3 against CK8,18,19 and HEA125 against human epithelial antigen) and a sensitive immunocytochemical staining using cytospin preparation to identify breast tumor cells in leukapheresis products (LP). This assay allowed detection of one tumor cel...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s004040050009
更新日期：2000-02-01 00:00:00
abstract：AIM:Breast cancer 2, early onset (BRCA2) has been reported to be associated with familial breast and ovarian cancer. Several proteins interact with conserved regions of BRCA2, which play significant roles in DNA damage repair and centrosomal localization. This study was aimed to identify a novel protein, Wilms tumor 1 ...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-016-4176-9
更新日期：2016-11-01 00:00:00
abstract：INTRODUCTION:In the western world, cannabis is the most widely used drug of abuse. Cannabinoid hyperemesis syndrome, which seems to be a rare paradoxical reaction in individuals with a particular predisposition, is characterized by cyclic severe nausea and vomiting in long-term cannabis users. While the symptoms are un...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-010-1811-8
更新日期：2011-11-01 00:00:00
abstract：:Hypertensive disorders of pregnancy are associated with an increased risk of maternal and fetal morbidity and mortality. The cause and the pathogenesis of the pregnancy-induced syndrome, preeclampsia, is still poorly understood. Published evidence of altered biomarkers for the endothelial dysfunction suggests that the...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
doi：10.1007/s00404-010-1538-6
更新日期：2010-11-01 00:00:00
abstract：PURPOSE:Prematurity is the most common cause of infant mortality and morbidity. To prevent this, the timing of parturition and its mechanisms should be understood. It is likely that inhibitor CD94/NKG2A positive decidual natural killer cells (uNK) provide for the continuation of pregnancy. Here, we aimed to evaluate wh...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-015-3978-5
更新日期：2016-08-01 00:00:00
