Abstract:
:We used a combination of 4 monoclonal antibodies (BM7, BM8 against MUC1, 5D3 against CK8,18,19 and HEA125 against human epithelial antigen) and a sensitive immunocytochemical staining using cytospin preparation to identify breast tumor cells in leukapheresis products (LP). This assay allowed detection of one tumor cell in 1x10(6) mononuclear cells (MC). In clinical specimens, tumor cells were detected in LP from 6 of 42 (14.3%) patients in the adjuvant treatment group, from 2 of 11 (18.2%) patients in the neoadjuvant treatment group and from 9 of 43 (20.1%) in the group of patients with metastatic disease. Tumor cell counts ranged from 0.25-5 cells in 1x10(6) normal cells per LP. The median tumor cell concentration was higher in specimens from patients with metastatic disease (median=0.96) than in specimens from patients in the adjuvant and neoadjuvant treatment groups (median=0.5 and 0.75). No significant differences between the epithelial cell positive group and the epithelial cell negative group with respect to tumor size, lymph nodes involvement, tumor grade, histological type and receptor were found. We conclude that immunocytochemical staining of cytospin preparation is a sensitive and simple method to detect and quantitate breast cancer cells in LP.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Lin YS,Zhong XY,Hohaus S,Kaul S,Haas Rdoi
10.1007/s004040050009subject
Has Abstractpub_date
2000-02-01 00:00:00pages
119-25issue
3eissn
0932-0067issn
1432-0711journal_volume
263pub_type
杂志文章abstract:OBJECTIVE:We aimed to evaluate perinatal outcome of seven pregnancies with twin reserve arterial perfusion sequence. MATERIALS AND METHODS:Study group included seven cases of acardiac twins. Out of seven acardiac twins, two cases were followed without interventions. We performed four alcohol ablation and one bipolar c...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-008-0746-9
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the outcome of hysteroscopic myomectomy in patients with infertility and recurrent abortions. MATERIALS AND METHODS:This was a retrospective clinical analysis of 186 patients who underwent hysteroscopic myomectomy by monopolar electrode loop. A second-look diagnostic hysteroscopy was performed i...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1531-0
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To evaluate maternal-fetal outcomes in women of advanced maternal age (AMA; >35 years old) and women of physiological maternal age as controls (C; <35 years old). METHODS:Single-center, retrospective case-control analysis, from January 1 to December 31, 2013. For each group, we evaluated obstetric history, num...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3367-5
更新日期:2014-12-01 00:00:00
abstract:UNLABELLED:The aim of this study was to determine the frequency of, indications for and clinical epidemiological characteristics in patients having their first cesarean section (FCS) and then to compare the data with that found in patients with repeated cesarean section (RCS). PATIENTS AND METHODS:A cross-sectional st...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-001-0255-6
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:To assess changing trends, role of the triad patient-pregnancy-health professionals and health care cost in emergency peripartum hysterectomy (EPH). METHODS:Demographics, indications, perinatal outcomes, perioperative complications in EPH cases performed in a 10-year period were extracted from the local birth ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05504-7
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:Laparoscopic-assisted myomectomy (LAM) is a minimally invasive procedure with many advantages. However, progressive formation of uterine arteriovenous fistula (AVF) after LAM is not described as a significant complication. CASE REPORT:A 39-year-old nulligravida underwent LAM for multiple myomas. On ultras...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-0981-8
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:Aggressive angiomyxoma (AAM) is a rare and often misdiagnosed tumor that is characterized by frequent local recurrences. This study aimed to investigate the clinicopathological characteristics, surgical experiences, and prognosis for aggressive angiomyxoma to improve the accuracy of diagnosis and develop treatm...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-020-05592-5
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To assess the main neonatal morbidity results in relation to induced labour indications. METHODS:Historical groups from a total of 3,817 deliveries over a three year period (2009, 2010 and 2011) in "Mancha-Centro" Hospital (Alcázar de San Juan) formed the study group. All programmed and non-avoidable caesarean...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3349-7
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:Laparoscopy has become the standard of care in the management of ovarian benign mucinous cystadenomas. One concern of the operative approach is the risk of recurrence. A previous study has found intraoperative cyst rupture and cystectomy to be the risk factors for recurrence. Our objective was to assess the inc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3543-7
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:As limited data among German women exist about HPV, Chlamydia trachomatis (CT) and Neisseria gonorrhoeae, we report the prevalence of these genital infections and general baseline demographics of the young German women enrolled in the phase III trials of the quadrivalent HPV vaccine. MATERIALS AND METHODS...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-008-0806-1
更新日期:2009-06-01 00:00:00
abstract:OBJECT:The aim of this study was to evaluate the lipid and protein oxidation and antioxidant function in preeclampsia patients and in normotensive pregnant women, as well as, to assess an association with the severity of the disease. METHOD:The study was carried out in 30 patients with mild preeclampsia, 30 with sever...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-002-0302-y
更新日期:2003-04-01 00:00:00
abstract:INTRODUCTION:Morbid obesity is perhaps the most common nutritional disorder seen in pregnancy, and morbidly obese parturients have more pregnancy complication than normal body mass index (BMI) pregnant patients. Combined spinal epidural anesthesia (CSEA) has become a well-established alternative to epidural analgesia f...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-004-0634-x
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:This prospective study was carried out in order to investigate changes in nutritional intake during pregnancy with regard to caloric intake and macronutrient composition in normal-weight pregnant women. METHODS:Using food scales, 32 healthy pregnant women estimated their food intake over a period of 2 days at ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1328-1
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to evaluate whether induction of breech delivery at term is feasible and safe for mother and child compared with spontaneous vaginal breech delivery. STUDY DESIGN:A total of 268 singleton term breech deliveries with an attempted vaginal delivery were identified in a single-center ret...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-015-3853-4
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Reactive oxygen species (ROS) are an array of molecules including oxygen-centered radicals, which are endowed with one or more unpaired electrons and non-radical oxygen derivatives such as hydrogen peroxide, which behave, to a large extent, like a double-edged sword in human sperm biology. This study aimed t...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-013-2801-4
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Ovarian pregnancy (OP) is a rare form of ectopic pregnancy and is still a medical challenge. Therefore, more studies about the time trends, risk factors and diagnostic measurements are needed for the efficient treatment of OP. METHODS:The datum of OP patients who were treated at the Second Hospital of Hebei...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05648-6
更新日期:2020-10-01 00:00:00
abstract::Pregnancy zone protein (PZP, alpha 2-PAG, SP3) was found to bind to plasmin in crossed affino-immunoelectrophoresis using sodium caseinate in the first dimension gel. The plasmin presence in the PZP-plasmin complex was confirmed by addition of antiserum against plasminogen to the gel. In crossed affino-immunoelectroph...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF00932082
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:We sought to evaluate the impact of obesity on the risk of spontaneous and medically indicated preterm birth in young women compared to adult women. METHODS:Florida vital records from 2004 to 2007 were used to obtain data. The study sample consisted of 290,807 mothers of whom 4,739 were adolescent girls < or =...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1213-y
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:As inconsistency exists concerning the rate and risk factors for re-laparotomy after cesarean section (CS), we aimed to determine the incidence, risk factors and indications for re-laparotomy after CS. METHODS:This is a retrospective study. Women underwent re-laparotomy following CS were compared to a contro...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3156-1
更新日期:2014-07-01 00:00:00
abstract:UNLABELLED:Does local injection with lidocaine plus epinephrine prior to vaginal reconstructive surgery with synthetic mesh affect exposure rates? A retrospective comparison. PURPOSE:To determine if local injection, prior to incision with lidocaine plus epinephrine (L + E) influences the rate of mesh exposure in the e...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1715-7
更新日期:2011-09-01 00:00:00
abstract::Primary malignant melanoma (MM) of the uterine cervix is a rare neoplasm. Historically all MMs of the cervix were thought to be metastatic. But after the discovery of melanocytes in the cervix in 1959, it was recognized that primary MM of the cervix exists as a separate entity. The treatment of this condition is not y...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-008-0912-0
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:Atosiban has been shown to be an effective tocolytic agent with a low rate of side effects during 24 to 33 weeks of gestation. Atosiban acts through selective, competitive inhibition of both oxytocin and vasopressin, so that there are reasons to assume that a tocolytic effect can also be achieved earlier in t...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-004-0652-8
更新日期:2005-06-01 00:00:00
abstract:PURPOSE:In a series of publications, we had developed the concept that uterine adenomyosis and pelvic endometriosis as well as endometriotic lesions at distant sites of the body share a common pathophysiology with endometriosis constituting a secondary phenomenon. Uterine auto-traumatization and the initiation of the m...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3437-8
更新日期:2015-04-01 00:00:00
abstract::Our case report describes a patient with clear cell fallopian tube carcinoma (histological grade 3; stage (FIGO): III c.) associated with an endometrial cyst of the tube wall. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040100223
更新日期:2002-07-01 00:00:00
abstract:PURPOSE:To investigate the precipitating factors of heart failure (HF) and to investigate the maternal and neonatal outcomes in pregnant women with HF. METHODS:We reviewed the medical records of pregnant women with HF who were treated at West China Second University Hospital between September 2012 and September 2017. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05350-2
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:To evaluate the role of Helicobacter pylori (H. pylori) in the pathogenesis of hyperemesis gravidarum (HG) and the value of adding a non teratogenic regimen for its treatment in intractable cases. METHODS:Eighty hyperemesis gravidarum cases were recruited from Ain Shams University out patient clinics. A comple...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-010-1759-8
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:The purpose of this investigation was to explore changes in patient preference regarding gynecologist's gender. METHODS:Using a standardized questionnaire, distributed in 1997 and 2018, a total of 1000 women were interviewed about preferences in terms of their choice of gynecologist and perceptions regarding g...
journal_title:Archives of gynecology and obstetrics
pub_type: 历史文章,杂志文章
doi:10.1007/s00404-019-05315-5
更新日期:2019-11-01 00:00:00
abstract::The fertility and pregnancy outcomes of the patients were studied, who previously underwent preservative operation for malignant tumors, including those of borderline malignancy, in our ward from 1981 to 1995. For each of the 9 patients, unilateral ovary was preserved, the range of their ages before operation was 10 t...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040000094
更新日期:2000-11-01 00:00:00
abstract:PURPOSE:Fetal akinesia deformation sequence (FADS) is a clinically and genetically heterogenous disorder. In this study, the different sonographic abnormalities are described in a larger number of affected fetuses. METHODS:This retrospective study included 79 cases of suspected FADS observed in our tertiary referral c...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-016-4017-x
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:Giant oocytes are potential sources of chromosomal abnormalities and should thus never be used in in vitro fertilization and embryo transfer (IVF-ET) procedures. The presence of giant oocytes may indicate the efficiency of the ovarian stimulation and can refer to the quality of sibling oocytes. METHODS:IVF cyc...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-015-3679-0
更新日期:2015-09-01 00:00:00