Abstract:
:Botulism poisoning results in a presynaptic failure of neuromuscular transmission, and may be expected to impair Eustachian tube and stapedius reflex function. The audiologic findings in five normal-hearing patients with type A botulism poisoning are presented. Results were varied. Two patients demonstrated type B or C tympanograms during the early stages, while three with normal middle ear function demonstrated marked bilateral or unilateral stapedius reflux threshold elevation. One patient had a reversible reflex decay, and the superimposition of a second stimulus upon the first resulted in complete recovery of reflex amplitude. A number of possible pathophysiological mechanisms are discussed.
journal_name
Ear Hearjournal_title
Ear and hearingauthors
Pijl Sdoi
10.1097/00003446-199108000-00007subject
Has Abstractpub_date
1991-08-01 00:00:00pages
281-6issue
4eissn
0196-0202issn
1538-4667journal_volume
12pub_type
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