Abstract:
:Attempts at radical excision of craniopharyngioma have been made increasingly possible by progress in neuroradiological imaging and the use of microscopic technique. Between 1977 and 1990, 50 patients of The National Hospital for Neurology and Neurosurgery, London, have undergone radical surgical excision of craniopharyngioma by the temporal route, with a small anterior temporal resection. Surgical mortality was 4%. Thirty-eight (76%) patients remain well at average follow-up of 30 months; 15% had major complications (hypothalamic damage, subdural haematoma, scalp collections requiring shunt drainage). There were three recurrences in those patients where the initial operations were considered as complete microscopic excision. It is concluded that maximal control of tumour recurrence by removal of all tumour accessible and visible to the surgical microscope is best achieved by a radical excision at the first operation.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Symon L,Pell MF,Habib AHdoi
10.3109/02688699109002877subject
Has Abstractpub_date
1991-01-01 00:00:00pages
539-49issue
6eissn
0268-8697issn
1360-046Xjournal_volume
5pub_type
杂志文章abstract::Endosaccular packing of inoperable aneurysms with electrolytic platinum coils was performed in 50 patients. Complete embolization of the aneurysms was achieved in 100% of small, 95% of large and 85% of giant aneurysms, with combined procedural and periprocedural morbidity and mortality rates of 6 and 4%, respectively....
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550040864
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Irrigation may elevate the intracranial pressure (ICP) during neuroendoscopic procedures. It is unlikely that rinsing the ventricles during routine endoscopic ventriculostomy causes persistent neurological impairment or damage, but procedures such as the endoscopic evacuation of intraventricular haematomas (...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.619596
更新日期:2012-04-01 00:00:00
abstract::The use of the flexible neuroendoscope and laser fenestration in the surgical management of a symptomatic cyst of cavum septum pellucidum is reported. Successful communication was established between the cyst cavity and the lateral ventricles using this technique. Satisfactory clinical and radiological improvement as ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550041179
更新日期:1995-01-01 00:00:00
abstract:INTRODUCTION:Intraspinal tumours are rare and principally managed surgically. Laminectomy, employed for access to the spinal canal, destroys the posterior tension band leading to a risk of kyphosis. Hemilaminectomy as an alternative may be less destructive, potentially reducing the risk of deformity and causing less po...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2014.1003026
更新日期:2015-06-01 00:00:00
abstract::The primary objective of neurophysiologic monitoring during surgery is to prevent permanent neurological sequelae. We prospectively evaluated whether the combined use of somatosensory- and motor-evoked potential (SEP/MEP) for intramedullary spinal cord tumor (IMSCT) surgery may be beneficial. Combined SEP/MEP monitori...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690902964744
更新日期:2009-08-01 00:00:00
abstract::Symptomatic, paradoxical intracranial tuberculomas is a rare occurrence. A case of tubercular meningitis, developing paradoxical tuberculomas alongside non-functional ventricular catheter is presented. Catheter removal facilitated removal of these paradoxical lesions, with the patient recovering to near-normal state a...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.690915
更新日期:2012-12-01 00:00:00
abstract::Giant anterior circulation aneurysms and some basilar aneurysms can cause problems due to their size, the presence of clot in the aneurysm and the difficulty of applying a clip without kinking the perforating vessels. By utilising cardiopulmonary bypass via the femoro-femoral perforating vessels. By utilising cardiopu...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698709035310
更新日期:1987-01-01 00:00:00
abstract:INTRODUCTION:Head injury is an important cause of death and disability in young people, with 1.4 million presentations each year in the UK.( 1 ) Extradural haematoma (EDH) is a potentially fatal head injury, which is easily remedied surgically. Several factors influence the mortality of EDH. The mortality of isolated E...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.709555
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:The graft site morbidity following iliac crest harvesting is significant. To overcome this, different bone substitutes like coral dowels, solvent dissolved bovine/human bone substitutes, and carbon fiber/titanium cages have been used. This study was undertaken to assess the postoperative radiological fusion ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2017.1297362
更新日期:2017-06-01 00:00:00
abstract::OBJECTIVES. To analyze the indications of surgical treatment, surgical management strategies and post-surgical outcome in patients with brainstem glioma (BSG). METHODS. In this retrospective study conducted from 1998 to 2012, 58 patients of surgically treated intrinsic BSG, meeting the inclusion criterion were enrolle...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.829562
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:To explore the changes of a series of cytokines before and after percutaneous balloon kyphoplasty (PKP) and prognostic markers for response to PKP. METHODS:From 1 January 2019 to 31 May 2019, all single-level lumbar osteoporotic vertebral compression fracture (OVCF) patients diagnosed by MRI who matched the ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1823941
更新日期:2020-10-14 00:00:00
abstract::Objective: Vaccination therapy using tumour antigen-loaded, autologous dendritic cells (DC) is a promising therapeutic approach alongside standard treatment for glioblastoma (GBM). However, reliable diagnostic criteria regarding therapy monitoring are not established. Here, we analysed the impact of additional 18F-flu...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1639615
更新日期:2019-08-13 00:00:00
abstract::Neuroendoscopy is increasingly used in the management of brain tumours and tumour related hydrocephalus and this study reviews the efficacy of neuroendoscopic interventions in this unit in patients with brain tumours. A series of 87 neuroendoscopic operations carried out in 77 patients with brain tumours over a 6-year...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/0268869021000030276
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND CONTEXT:Transforaminal epidural steroid injection (TFESI) is recognised as a treatment for symptomatic lumbar disc herniation, whilst surgical decompression is generally thought to be the most effective treatment option for lumbar spinal stenosis. There is little available literature examining the effect of ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2016.1206188
更新日期:2017-04-01 00:00:00
abstract::In the first prospective comparison of 'scan-negative' (n=11) and 'scan-positive' (n=7) patients with cauda equina syndrome (CES) we found that Hoover's sign of functional leg weakness but not routine clinical features differentiated the two groups (p<0.02). This offers a new direction of study in this area, although ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2014.1003032
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:The placement of external ventricular drain (EVD) is a common neurosurgical procedure to drain cerebrospinal fluid (CSF) in many acute neurosurgical conditions that disrupt the normal CSF absorption pathway. Infection is the primary complication with infection rates ranging between 0% and 45%, and this is ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.578770
更新日期:2011-10-01 00:00:00
abstract::Growing skull fractures indicate underlying brain damage which is an important aetiological factor in their development. Two cases of growing skull fractures managed successfully with shunt surgery are presented. In one, the growing skull fracture was associated with an underlying tense occipital porencephalic cyst an...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699108998454
更新日期:1991-01-01 00:00:00
abstract::The objective was to measure metabolic changes monitored by bedside microdialysis during impending and manifest hypoxia in traumatic brain injury. In 41 patients, a PtiO2-catheter (Licox; 1/min) was placed into non-lesioned frontal white matter together with a microdialysis catheter (CMA, hourly). Data were analysed f...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690310001601234
更新日期:2003-08-01 00:00:00
abstract::Purpose: To depict the specific brain networks that are modulated by deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson's disease (PD), using diffusion tensor imaging-based fibre tractography (DTI-FT).Materials and methods: Nine patients who received bilateral STN-DBS for PD were included. Elec...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1701630
更新日期:2020-04-01 00:00:00
abstract::Despite advances in imaging of the brain, an accurate diagnosis of brain lesions requires tissue sampling and histological verification. A series of CT-directed procedures has been performed in 300 patients with deep sited, multiple, diffuse, extensive, small or inflammatory lesions, brain stem haematomas and tumours ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698909002810
更新日期:1989-01-01 00:00:00
abstract::Gliomatosis cerebri (GC), which mainly consists of oligodendroglial tumour cells, is rare and six cases have been documented to date. We present a new case of oligodendroglial gliomatosis cerebri with a favourable response to combination treatment using surgery, radiotherapy and chemotherapy. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690410001732823
更新日期:2004-06-01 00:00:00
abstract::Non-traumatic 'spontaneous' CSF fistulae are uncommon. The clinical features of 23 patients treated for non-traumatic CSF fistulae are presented. Twenty of these patients had normal CSF pressure and six developed meningitis. Surgical repair of these fistulae is recommended in order to reduce the risk of meningitis. Fo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699109005187
更新日期:1991-01-01 00:00:00
abstract::The objective of this study was to investigate if there are possible gender differences in relation to outcome following closed severe traumatic brain injury (TBI) in a predominantly Asian population. A study was conducted using our prospectively maintained TBI database of 672 patients with severe TBI admitted into ou...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690600682259
更新日期:2006-04-01 00:00:00
abstract::OCT4 expresses variably in primary intracranial germinomas. In this study, we tested our hypothesis that such variation of OCT4 is predictive of outcome in primary intracranial germinomas. Thirty-one histologically identified CNS germinoma patients were enrolled in our study. We collected medical data, immunohistochem...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.605483
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:To assess the clinical and radiographic outcomes and complications of anterior lumbar interbody fusion (ALIF) versus transforaminal lumbar interbody fusion (TLIF). METHODS:A systematic literature search was conducted from six electronic databases. The relative risk and weighted mean difference (WMD) were used ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,meta分析,评审
doi:10.3109/02688697.2015.1036838
更新日期:2015-01-01 00:00:00
abstract::A case of dysplastic cerebellar gangliocytoma recurring after 20 years and representing with subarachnoid haemorrhage is described. Evidence in favour of a neoplastic pathogenesis is presented. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699209002919
更新日期:1992-01-01 00:00:00
abstract::Modern cancer therapy has improved the prognosis for several tumour types. This, however, does not apply to the largest group of brain tumours, the malignant astrocytomas grades III-IV. Hence, there is need for new ideas to improve treatment. Ca2+ and the Ca(2+)-binding protein calmodulin have been shown to be involve...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699409027965
更新日期:1994-01-01 00:00:00
abstract::Multicentre gliomas are a well recognized entity but the occurrence of such tumours both above and below the tentorium remains uncommon. We report the case of an 11-year-old boy who underwent stereotactic biopsy of a brain stem ring enhancing tumour with histology of an anaplastic astrocytoma (Grade 3). Nine months fo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699109002887
更新日期:1991-01-01 00:00:00
abstract::The results from the Danish model of acoustic neuroma surgery are presented. In the period from 1976 to 1985, 300 patients with acoustic neuromas were operated upon using the translabyrinthine procedure. Only one small intrameatal tumour was encountered; 96 tumours were medium sized and 203 were larger than 25 mm. Of ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698909002815
更新日期:1989-01-01 00:00:00
abstract::Background: The chronic constriction injury (CCI) of the infraorbital nerve (ION) has been used to establish an animal mode of trigeminal neuralgia (TN), but key parameters of the model have not been quantified until now. Objective: The aim of the study was to quantify a standard of pain threshold to evaluate a succes...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1538483
更新日期:2019-08-01 00:00:00