Intrathecal baclofen in children with spastic cerebral palsy: a double-blind, randomized, placebo-controlled, dose-finding study.

abstract：:This randomized double blind AB/BA cross-over trial evaluates the effect of oral modafinil versus placebo on spasticity, function, and quality of life in children with cerebral palsy (CP). Outcomes were measured at the start and end of both 8-week treatment periods (modafinil and placebo). The order of the treatment p...

journal_title：Developmental medicine and child neurology

authors： Murphy AM,Milo-Manson G,Best A,Campbell KA,Fehlings D

更新日期：2008-07-01 00:00:00

abstract：:This study retrospectively evaluated the safety and efficacy of selective dorsal rhizotomy (SDR) in participants who underwent a rigorous selection process, uniform surgical procedure, and a standardized postoperative rehabilitation process. Outcome measures assessed were the Ashworth scale for spasticity, the Gillett...

journal_title：Developmental medicine and child neurology

authors： Trost JP,Schwartz MH,Krach LE,Dunn ME,Novacheck TF

更新日期：2008-10-01 00:00:00

abstract：:Endogenous opioid dysfunction hypotheses for the development of autism are reviewed, along with clinical empirical studies of opiate antagonists in autism and self-injurious behaviour. There is not yet sufficient evidence to suggest the use of opiate antagonists in the treatment of autism. Further research, particular...

journal_title：Developmental medicine and child neurology

authors： Gillberg C

更新日期：1995-03-01 00:00:00

abstract：AIM:This population-based study aimed to estimate the impact of neonatal seizures on subsequent neurological outcomes, regardless of underlying etiology. METHOD:We performed a retrospective cohort study (1st January 2009-31st December 2014), using a USA nationwide claims database. Newborn infants enrolled in 2009 were...

journal_title：Developmental medicine and child neurology

authors： Oh A,Thurman DJ,Kim H

更新日期：2019-06-01 00:00:00

abstract：:The clinical importance of intermittent intracranial pressure (ICP) elevations during sleep in hydrocephalic children is unclear. Eight studies of continuous ICP monitoring with simultaneous cerebral blood-flow velocity (CBFV) measurements were recorded during sleep in seven hydrocephalic children aged between one and...

journal_title：Developmental medicine and child neurology

authors： Goh D,Minns RA,Pye SD,Steers AJ

更新日期：1992-08-01 00:00:00

abstract：:Perinatal hypoxic-ischaemic encephalopathy (HIE) occurs in 1 to 3 per 1000 term births. HIE is not preventable in most cases, and therapies are limited. Hypothermia improves outcomes and is the current standard of care. Yet, clinical trials suggest that 44-53% of infants who receive hypothermia will die or suffer mode...

journal_title：Developmental medicine and child neurology

authors： Wu YW,Gonzalez FF

更新日期：2015-04-01 00:00:00

abstract：AIM:Apolipoprotein E (APOE, protein; [ApoE, gene]) is a lipid transport protein abundantly present in brain cells. We investigated whether the APOE genotype is associated with cerebral palsy (CP) and whether patients with CP with comorbid conditions and more severe neurological deficits are likely to have a particular ...

journal_title：Developmental medicine and child neurology

authors： Braga LW,Borigato EV,Speck-Martins CE,Imamura EU,Gorges AM,Izumi AP,Dantas RC,Nunes LG

更新日期：2010-07-01 00:00:00

abstract：:Epilepsy has a significant impact on a child's life, the extent to which is based on four factors: epilepsy, cognition, behavioral, and physical/neurologic function. This study evaluates the ability of the 44-item Impact of Childhood Neurologic Disability Scale (ICND) to assess each of these four realms. Parents of ch...

journal_title：Developmental medicine and child neurology

authors： Camfield C,Breau L,Camfield P

更新日期：2003-03-01 00:00:00

abstract：AIM:The aim of this study was to assess whether any memory impairment co-occurring with language impairment is global, affecting both verbal and visual domains, or domain specific. METHOD:Visual and verbal memory, learning, and processing speed were assessed in children aged 6 years to 16 years 11 months (mean 9 y 9 m...

journal_title：Developmental medicine and child neurology

authors： Baird G,Dworzynski K,Slonims V,Simonoff E

更新日期：2010-06-01 00:00:00

abstract：:Twenty-three Swedish children aged five to 18 years who fulfilled specific criteria for Asperger syndrome were examined and compared with an age- and IQ-matched group with infantile autism. The boy:girl ratio was 10:1. Less than 10 per cent were mentally retarded and 17 per cent were of above-average intelligence. Apa...

journal_title：Developmental medicine and child neurology

authors： Gillberg C

更新日期：1989-08-01 00:00:00

abstract：AIM:Controversy surrounds the distinction between high-functioning autism (HFA) and Asperger disorder, but motor abnormalities are associated features of both conditions. This study examined motor cortical inhibition and excitability in HFA and Asperger disorder using transcranial magnetic stimulation (TMS). METHOD:Pa...

journal_title：Developmental medicine and child neurology

authors： Enticott PG,Rinehart NJ,Tonge BJ,Bradshaw JL,Fitzgerald PB

更新日期：2010-08-01 00:00:00

abstract：:The results are presented of a follow-up study of 155 Dutch children after the first febrile seizure. Of these initially untreated children 37 per cent had had at least one, 30 per cent at least two and 17 per cent at least three subsequent seizures. The vulnerable period for recurrent seizures after the first febrile...

journal_title：Developmental medicine and child neurology

authors： Offringa M,Derksen-Lubsen G,Bossuyt PM,Lubsen J

更新日期：1992-01-01 00:00:00

abstract：:The purpose of this study was to compare the cumulative efficacy (three treatment sessions) of botulinum toxin A (BTX-A) alone, casting alone, and the combination of BTX-A and casting in the management of dynamic equinus in ambulatory children with spastic cerebral palsy (CP). Thirty-nine children with spastic CP (mea...

journal_title：Developmental medicine and child neurology

authors： Ackman JD,Russman BS,Thomas SS,Buckon CE,Sussman MD,Masso P,Sanders J,D'Astous J,Aiona MD,Shriners Hospitals BTX-A Study Group.

更新日期：2005-09-01 00:00:00

abstract：AIM:In children with Friedreich ataxia (FRDA), ataxia is assessed using the surrogate marker the International Cooperative Ataxia Rating Scale (ICARS). We aimed to determine whether ICARS scores in children with FRDA are confounded by muscle weakness. METHOD:In 12 children with FRDA (10 males, two females; mean age 13...

journal_title：Developmental medicine and child neurology

authors： Sival DA,Pouwels ME,Van Brederode A,Maurits NM,Verschuuren-Bemelmans CC,Brunt ER,Du Marchie Sarvaas GJ,Verbeek RJ,Brouwer OF,Van Der Hoeven JH

更新日期：2011-06-01 00:00:00

abstract：AIM:To determine whether assisted reproductive technologies (ART) were more likely to be the method of conception in singletons with cerebral palsy (CP) than in those without CP. METHOD:Singletons with CP born between 1991 and 2004 were selected from the Victorian Cerebral Palsy Register and matched for birth year to ...

journal_title：Developmental medicine and child neurology

authors： Reid SM,Jaques AM,Susanto C,Breheny S,Reddihough DS,Halliday J

更新日期：2010-07-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the efficacy and effectiveness of exercise interventions that may improve postural control in children with cerebral palsy (CP). METHOD:A systematic review was performed using American Academy of Cerebral Palsy and Developmental Medicine (AACPDM) and Preferred Reporting Items ...

journal_title：Developmental medicine and child neurology

authors： Dewar R,Love S,Johnston LM

更新日期：2015-06-01 00:00:00

abstract：AIM:Parental report is often relied on to measure performance of activities in children with cerebral palsy (CP). This study examined whether the Functional Mobility Scale (FMS) accurately reflects performance of mobility in children with CP. METHOD:Eighteen children with spastic CP (11 males, seven females; mean age ...

journal_title：Developmental medicine and child neurology

authors： Harvey A,Baker R,Morris ME,Hough J,Hughes M,Graham HK

更新日期：2010-02-01 00:00:00

abstract：:This study compared the results of reflex modification (RM)--an objective technique for assessing brainstem sensorineural processing--with those of auditory brainstem response (ABR) for a group of high-risk infants at comparable postconceptional ages. For the RM procedure, an eyeblink-eliciting tap to the glabella was...

journal_title：Developmental medicine and child neurology

authors： Anday EK,Cohen ME,Hoffman HS

更新日期：1991-02-01 00:00:00

abstract：:Sixty-seven consecutive patients (59 females, eight males; mean age 13.6 years, age range 8.1 to 18 years) with adolescent idiopathic scoliosis were evaluated for segmental dystonia, thermal and vibratory thresholds, and cortical somatosensory evoked potentials (cSEPs). Clinically, there were no signs of segmental dys...

journal_title：Developmental medicine and child neurology

authors： Olafsson Y,Odergren T,Persson HE,Saraste H

更新日期：2002-02-01 00:00:00

abstract：:We report two sisters with extensive bilateral periventricular haemorrhagic infarction (PVHI) causing cerebral palsy (CP). The older sister presented at 20 months with cortical visual blindness, spastic diplegia, and purpura fulminans. The younger sister presented aged 3 days old with apnoeas and multifocal seizures. ...

journal_title：Developmental medicine and child neurology

authors： Fong CY,Mumford AD,Likeman MJ,Jardine PE

更新日期：2010-05-01 00:00:00

abstract：:Cerebral palsy (CP) is a complex disorder and children frequently have multiple impairments. Dystonia is a particularly frustrating impairment that interferes with rehabilitation and function and is difficult to treat. Of the available treatments, deep brain stimulation (DBS) has emerged as an option with the potentia...

journal_title：Developmental medicine and child neurology

authors： Sanger TD

更新日期：2020-01-01 00:00:00

abstract：AIM:To evaluate construct and predictive validity of the Communication Function Classification System (CFCS) for use with preschool children with a range of speech and language disorders. METHOD:Seventy-seven preschool children with speech and language disorders (50 males, 27 females; mean 2y 7mo, standard deviation [...

journal_title：Developmental medicine and child neurology

authors： Hidecker MJ,Cunningham BJ,Thomas-Stonell N,Oddson B,Rosenbaum P

更新日期：2017-05-01 00:00:00

abstract：AIM:To examine self- and proxy-reported symptoms of depression in children with epilepsy. METHOD:This was a prospective longitudinal cohort study of children with epilepsy. Participants were treated at six Canadian tertiary-care centers and followed over 28 months with repeated assessments of child self-reported sympt...

journal_title：Developmental medicine and child neurology

authors： Rosic T,Avery L,Streiner DL,Ferro MA,Rosenbaum P,Cunningham C,Ronen GM

更新日期：2020-05-01 00:00:00

abstract：AIM:Difficult-to-treat epilepsies and attention-deficit-hyperactivity disorder (ADHD) often co-occur. Because of concerns about the use of stimulants in children with this comorbidity, the impact of ADHD treatment on seizure frequency and severity is not known. This pilot study evaluated the safety and efficacy of meth...

journal_title：Developmental medicine and child neurology

authors： Santos K,Palmini A,Radziuk AL,Rotert R,Bastos F,Booij L,Fernandes BS

更新日期：2013-07-01 00:00:00

abstract：:We assessed the influence of equinus gait treatments on the vertical displacement of the body's centre of mass (COM) in 21 patients with cerebral palsy (14 males, 7 females; mean age 8 y 9 mo [SD 2 y]; range 3 y 7 mo-17 y) presenting different topographical types (quadriplegia, n = 1; diplegia, n = 6; right hemiplegia...

journal_title：Developmental medicine and child neurology

authors： Massaad F,van den Hecke A,Renders A,Detrembleur C

更新日期：2006-10-01 00:00:00

abstract：:The aim of this study was to evaluate cognitive development at the onset of West syndrome (WS) with regard to electroencephalogram (EEG) patterns and visual function. Twenty-five patients (14 males, 11 females) at the onset of spasms (T0) in WS and 2 months later (T1) underwent a full clinical evaluation, including ne...

journal_title：Developmental medicine and child neurology

authors： Randò T,Baranello G,Ricci D,Guzzetta A,Tinelli F,Biagioni E,La Torre G,Epifanio R,Signorini S,Fazzi E,Mercuri E,Cioni G,Guzzetta F

更新日期：2005-11-01 00:00:00

abstract：AIM:Scoliosis is a frequently occurring and serious complication of severe cerebral palsy (CP). This systematic review aims to the assess the risk factors associated with the emergence and progression of scoliosis in children with CP functioning at level IV or V of the Gross Motor Function Classification System (GMFCS)...

journal_title：Developmental medicine and child neurology

authors： Loeters MJ,Maathuis CG,Hadders-Algra M

更新日期：2010-07-01 00:00:00

abstract：AIM:To describe the long-term outcomes of children by the time they reached school age with vein of Galen aneurysmal malformation (VGAM). METHOD:This was a retrospective observational study on a consecutive cohort of patients with VGAM. We included patients with at least one Francophone parent, aged between 6 and 11 y...

journal_title：Developmental medicine and child neurology

authors： Taffin H,Maurey H,Ozanne A,Durand P,Husson B,Knebel JF,Adamsbaum C,Deiva K,Saliou G

更新日期：2020-06-01 00:00:00

abstract：:A group of 102 neurologically normal neonates with gestations between 26 and 40 weeks, without abnormality on cranial ultrasound, underwent evoked response testing. Satisfactory results were obtained for 90 per cent of the infants. Normal ranges with 95 per cent tolerance limits for the short-latency N1 component of t...

journal_title：Developmental medicine and child neurology

authors： Klimach VJ,Cooke RW

更新日期：1988-04-01 00:00:00

abstract：:This study examined the social and academic implications of mainstream, mainstream and special (combined) or special-class education for 31 adolescents with spina bifida, and for their primary caretakers. The Peabody Picture Vocabulary Test and the UCLA Loneliness Scale (adolescents) and the Personality Inventory for ...

journal_title：Developmental medicine and child neurology

authors： Lord J,Varzos N,Behrman B,Wicks J,Wicks D

更新日期：1990-01-01 00:00:00