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Thrombosis of sinus sagitalis during puerperium caused by thrombophilic gene mutation.

Abstract：

:Cerebral veno-sinus thrombosis (CVT) during puerperium may have fatal consequences. A nonspecific clinical picture must be complete with computed tomography of the brain and digital substract angiography of the brain blood vessels, and, once the clinical diagnosis is confirmed, coagulation tests and genetic analysis of the coagulation factor are to be made as well. Genetic polymorphisms associated with thrombophilia such as factor V Leiden, prothrombin G20210A, MTHFR C677T, ACE and PIA1/A2 may be the cause of the hypercoagulability that results in CVT.

journal_name

J Thromb Thrombolysis

journal_title

Journal of thrombosis and thrombolysis

authors

Titlic M,Pavelin S,Tonkic A,Jukic I,Buca A,Andelinovic S

doi

10.1007/s11239-007-0061-5

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

270-2

issue

3

eissn

0929-5305

issn

1573-742X

journal_volume

25

pub_type

杂志文章

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