Abstract：
:Recent studies of testicular descent suggest not only that the gubernaculum does not initially attach to the scrotum, but also that it must migrate from the groin. Two findings suggest that the gubernaculum may behave like an embryonic limb bud during this phase. First, the active growth centre is at the distal tip of the gubernaculum. Secondly, the gubernaculum is loose in the subcutaneous tissues beneath Scarpa's fascia. The free protrusion of the gubernaculum from the abdominal wall was so reminiscent of a developing embryonic limb bud, we thought that the biological controls of both processus may be similar. This review examines what is known about vertebrate limb bud development, and compares the mechanisms to what has recently been discovered in the gubernaculum. The hypothesis that both processes may be similar is initially consistent with the current facts, encouraging us to investigate this further experimentally.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Huynh J,Shenker NS,Nightingale S,Hutson JMdoi
10.1007/s00383-007-1907-9subject
Has Abstractpub_date
2007-07-01 00:00:00pages
617-24issue
7eissn
0179-0358issn
1437-9813journal_volume
23pub_type
杂志文章,评审abstract：:Our case report details the clinical course and management of a neonate with acute life-threatening respiratory distress presenting soon after birth. She needed intubation and ventilation. A pericardial cyst was diagnosed after a CT scan and 2D echo investigation. As a temporizing procedure the fluid was tapped and th...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-0970-0
更新日期：2003-11-01 00:00:00
abstract：:70 cases of gastroschisis (GS) were surgically treated at the Pediatric Surgical University Clinic, Münster, from 1984 through 1998. The defect occurred more frequently in males (44) than females (26). The average birth weight was 2,383 g and mean gestational age 36.8 weeks. 9 infants (12.9%) were delivered vaginally ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0799-y
更新日期：2002-09-01 00:00:00
abstract：:The aim of this study was to assess the feasibility of complex minimally invasive surgery in neonates (and infants <5 kg). A systematic search of databases was performed. Inguinal herniotomy and pyloromyotomy were specifically excluded. Various operations were assessed for operative times, conversion rates, complicati...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-008-2318-2
更新日期：2009-03-01 00:00:00
abstract：:Recent reports indicate that extracellular matrix and cytoskeleton plasmalemmal elements are altered in infantile hypertrophic pyloric stenosis (IHPS). Desmin is a cytoskeletal protein that is important for the organization and function of muscular fibers. It has been found to be increased in the smooth muscle in chro...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050745
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:This study reviews the results of our previously described modification of the minimally invasive (Nuss) procedure for correction of pectus excavatum. It utilizes a subxyphoid incision with central fixation to maximize safe bar passage and minimize bar displacement. METHODS:Consecutive patients corrected wi...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4195-z
更新日期：2018-01-01 00:00:00
abstract：:From January 1972 to June 1993, 166 patients with posterior urethral valves (PUV) were treated in our surgical department, 59 with a milder form of PUV (upper urinary tract [UUT] complication rate 29%) and 107 with a severer form (UUT complication rate 96.3%). Only the latter group was studied for long-term (mean 9.3 ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00497807
更新日期：1996-06-01 00:00:00
abstract：PURPOSE:Ghrelin was recently reported to promote recovery from hepatic injury. We hypothesized that it could also be associated with clinical recovery of the transplanted liver from ischemia and reperfusion injury. Our aims were to investigate perioperative ghrelin changes following pediatric living donor liver transpl...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-019-04463-8
更新日期：2019-06-01 00:00:00
abstract：:Umbilical hernias occur frequently in children but complications are very rare and thus surgery is not routinely indicated. In this literature review, we report 19 cases of spontaneous evisceration of abdominal contents through umbilical hernias. Precipitating causes included umbilical ulceration or sepsis, crying, re...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-012-3076-8
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:Rats are common intruders into human settlements. Apart from their role as disease vectors, they can also cause bite injuries. We describe the clinical course of a series of children with rat bites, and characterise the injures. METHODS:A retrospective review of hospital records of children admitted for rat bi...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-020-04799-6
更新日期：2021-01-21 00:00:00
abstract：:A newborn case with cardiac rhabdomyoma is presented to discuss the differential diagnosis of mediastinal tumors around the heart in children. The diagnosis of rhabdomyoma can be suggested by modern visualization methods such as computerized tomography, magnetic resonance imaging and echocardiography. However, surgery...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1875-0
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Cervicovaginal atresia is a rare Mullerian anomaly. The management of cervicovaginal atresia has evolved from historical recommendations of hysterectomy to various reconstructive procedures more recently. The latter carries a risk of significant morbidity and unknown fertility. We present our experience in t...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3550-6
更新日期：2014-10-01 00:00:00
abstract：:The presentation of congenital diaphragmatic hernia (CDH) at birth may fall outside the typical features (cyanosis, tachypnea and respiratory failure), manifesting, instead, also with others pictures that make the diagnosis difficult or even impossible. We report a case of CDH presenting as a pneumothorax and a perfor...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-007-2000-0
更新日期：2008-03-01 00:00:00
abstract：:It is widely accepted that there are degenerative changes and decreased spermatogenesis in the contralateral descended testis (CDT) in unilateral undescended testis (UUDT). While some investigators have postulated that the mechanism may be related to primary (congenital) or secondary (autoimmune, vascular, and neural)...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000532
更新日期：2001-07-01 00:00:00
abstract：AIM:Although liver abscess (LA) is prevalent worldwide, especially in developing countries, there is a paucity of data regarding the protocol for management of LA in children. The aim of this study was to analyze the outcome of a protocol-based management of pediatric LA from a single institution. MATERIALS AND METHOD...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-4009-8
更新日期：2017-02-01 00:00:00
abstract：:Pulmonary sequestration is a rare congenital pulmonary malformation. We report a case of a 10-month-old infant with intralobar pulmonary sequestration diagnosed in utero. The lesion had an uncommon blood supply consisting of three large arteries deriving from the thoracic aorta and venous drainage into the inferior ve...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3088-4
更新日期：2012-07-01 00:00:00
abstract：PURPOSE:Recognition of physical child abuse is imperative for ensuring children's safety. Screening tools (ST) may increase identification of physical abuse; however, the extent of their use is unknown. This study assessed use of STs for physical abuse in children's hospitals and determined attitudes regarding STs. ME...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-3916-z
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Sacrococcygeal teratoma (SCT) is a rare childhood malignancy. Although overall survival is favorable, recurrent tumors are associated with poor outcomes. As most recurrences occur within 3 years of presentation, the utility of long-term surveillance is uncertain. METHODS:Patients with SCTs evaluated and man...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4132-1
更新日期：2017-11-01 00:00:00
abstract：:Robotic assisted minimal invasive surgery (RMIS) is a new resource popular in some surgical specialties but not yet in pediatric surgery. There are numerous advantages of robotic surgical technology in adult patients well documented in the literature. The purpose of this study is to define the feasibility, safety, and...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2901-9
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:Lgr5+ intestinal epithelial stem cells (ISCs) crucial for intestinal epithelial regeneration are impaired during necrotizing enterocolitis. This study aims to investigate the influence of different stressors on intestinal epithelial injury and regeneration in vitro. METHODS:Intestinal epithelial cells (IEC-18)...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4183-3
更新日期：2018-02-01 00:00:00
abstract：:The authors report two patients with extrahepatic portal hypertension and repeated massive bleeding from esophageal varices who underwent urgent distal splenorenal shunting (DSRS) after having proved refractory to medical treatment, endoscopic sclerotherapy, and ligation of esophageal varices. Their ages and weights w...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830100014
更新日期：2001-11-01 00:00:00
abstract：:This article describes five cases of congenital epulis, a rare and benign swelling in the mouth of a newborn, which is not widely known. We present five cases: four cases presented as single pedunculated nodules of the gingiva and in one case two nodules were present. Of all, 50% were located at the maxilla. Excision ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-008-2304-8
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:The goal of this study was to determine the degree of consensus in the management of spinal cord tethering (TC) in patients with anorectal malformation (ARM) in a large cohort of European pediatric centers. METHODS:A survey was sent to pediatric surgeons (one per center) members of the ARM-Net Consortium. RES...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-017-4105-4
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:This study aimed to characterize the surgical complications, especially gastroesophageal reflux disease (GERD), intestinal adhesion obstruction (IAO), and diaphragmatic hernia recurrence, in patients with congenital diaphragmatic hernia (CDH). METHODS:Between January 1995 and December 2013, we determined the i...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3575-x
更新日期：2014-09-01 00:00:00
abstract：:This report describes three children, age range 7 weeks to 5 months, who presented with obstructive jaundice secondary to gallstones. Previous Escherichia coli septicaemia and frusemide therapy were predisposing risk factors in two of the patients. All three were successfully treated with cholecystectomy and explorati...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:In order to evaluate the gubernaculum (GN) abnormalities quantitatively in patients with undescended testes (UDT), the area and attachment site of the gubernaculum were evaluated. PATIENTS AND METHODS:Sixty-seven testes from 61 patients with an undescended testis treated in the past 11 years at our institution...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3597-4
更新日期：2014-11-01 00:00:00
abstract：:The occurrence of a coexisting congenital diaphragmatic hernia (CDH) and esophageal atresia (EA) with distal tracheoesophageal fistula is extremely rare and is considered highly lethal. Only 19 cases of CDH with EA have been reported in the world literature to date. This is a very challenging clinical problem, and the...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s003830050448
更新日期：1998-11-01 00:00:00
abstract：BACKGROUND:The natural history of patients with antenatally diagnosed congenital cystic adenomatoid malformation of the lung (CCAM) is still fully unknown. In symptomatic patients with respiratory distress, an operation is performed during the neonatal period. However, in asymptomatic patients, the optimal timing of th...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2431-x
更新日期：2009-09-01 00:00:00
abstract：:Sixty-seven patients with resected Wilms' tumour>1.0 kg are reported. Surgery in this group is difficult, may result in the sacrifice of adjacent structures, and frequently upstages the patient. Mortality is related to tumour burden. Whilst there is little agreement on the therapeutic implications of failure to respon...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1678-8
更新日期：2006-05-01 00:00:00
abstract：:Children with chronic idiopathic constipation (CIC) often end up at the surgeon when medical treatments have failed. This opinion piece discusses a recently described pattern of CIC called 'Rapid transit constipation (RTC)' first identified in 2011 as part of surgical workup. RTC was identified using a nuclear medicin...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-019-04587-x
更新日期：2020-01-01 00:00:00
abstract：:Measurement of testicular volume is a more readily available method of estimating spermatogenesis in adolescence. Traditionally, testicular volumes have been measured with different type of orchidometers or calipers. The most widely used orchidometer is the Prader orchidometer introduced in 1966. This type of orchidom...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1470-1
更新日期：2005-07-01 00:00:00
