Abstract：
:The aim of this study is to isolate, characterize, and identify the bioactivity of an angiogenesis inhibitor derived from the Dasyatis akajei cartilage. By guanidine hydrochloride extract, refrigerated centrifugation, ultrafiltration, 20%-80% acetone precipitation, dialysis and refrigerated desiccation, the DCGE (Dasyatis akajei cartilage guanidine hydrochloride extract) of molecular weights from 3 kDa to approximately 300 kDa was obtained from the Dasyatis akajei cartilage. DCAI (Dasyatis akajei cartilage angiogenesis inhibitor) from 20%-30% acetone precipitation of DCGE was found to have the strongest angiogenesis inhibitory effect. Protein quantification of DCAI shows the main components were proteins with about 73.5% weight of the total DCAI. The bioactivity of the DCAI was investigated by inhibiting the formation of the blood vessels of the chick embryo chorioallantoic membrane (CAM). The ratio between the vascular area and the non-vascular area (VA/ NVA) in sampling point was used for quantitative analysis of the inhibitory effect of DCAI, which can be obtained by computer image analysis system (CIAS). Compared with the control group, the sampling point of the DCAI group had significantly lower VA/NVA. A large area of blood vessels in sampling point was significantly faded and the vascular structure was blurred with broken branches accompanied by the decreased density of vessels. The inhibitory effect with same dosage of DCAI is about ten times higher than that in the positive control group (chondroitin sulphate group) and the effect increases with the concentration of DCAI. The results from the present study indicates that the DCAI from Dasyatis akajei cartilage has an angiogenesis inhibitory effect, and there is also a positive correlation between the concentration and the inhibitory effect.
journal_name
Asia Pac J Clin Nutrjournal_title
Asia Pacific journal of clinical nutritionauthors
Luo H,Xu J,Yu Xsubject
Has Abstractpub_date
2007-01-01 00:00:00pages
286-9eissn
0964-7058issn
1440-6047journal_volume
16 Suppl 1pub_type
杂志文章abstract：:The existence of 'intestinal failure' was proposed. This pathologic condition may occur in two distinct forms, ie short bowel syndrome marked by a gross reduction in functioning gut mass and impaired intestinal function (impairment of motility and extensive parenchymatous disorders). This has been newly recognized as ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:The centre of origin of the oil palm is the tropical rain forest region of West Africa. It is considered to be the 200-300 kilometre wide coastal belt between Liberia and Mayumbe. The oil palm tree has remained the 'tree of life' of Yoruba land as well as of other parts of southern West Africa to which it is indigenou...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2003-01-01 00:00:00
abstract：:Iron status, prevalence of iron deficiency and elevated iron stores, and the effect of gastrointestinal ulceration on iron status in free-living Taiwanese elderly persons were all assessed in a nationally representative, cross-sectional nutrition survey--the Elderly NAHSIT. The survey included blood measurements of ir...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:This study explored the association between dietary habits and overweight and obesity in adolescents from Xi'an City, China. A cross-sectional sample of 1804 adolescents was recruited in 2004 from 30 junior high schools in six districts of Xi'an City, northwest China. Weight and height was measured and eating habits a...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:For delivery of parenteral nutrition (PN), long-term central access is often required in infants with intestinal failure (IF). Compared to central venous catheters (CVCs), peripherally inserted central catheters (PICCs) are less invasive, as they are smaller, and they can even be placed withou...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.201811_27(6).0008
更新日期：2018-01-01 00:00:00
abstract：:Malnutrition in hospitals often goes unrecognized. At present, no nutrition screening tool provides satisfactory re-sults in identifying nutritional risk. Most tools depend on weight and height as criteria for diagnosing malnutrition. Weight is not recorded in many patients and some tools are time-consuming. An inclus...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2013.22.4.06
更新日期：2013-01-01 00:00:00
abstract：:The health status of Australia's indigenous people remains the worst of any subgroup within the population, and there is little evidence of any significant improvement over the past two decades, a situation unprecedented on a world scale. Compared with non-indigenous Australians, adult life expectancy is reduced by 15...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1046/j.0964-7058.2002.00352.x
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Nutrition and inflammation play a crucial role in the development of cancer. The prognostic value of the prognostic nutritional index (PNI) has been confirmed in some types of human cancers. This study analyzed the prognostic significance of the preoperative PNI in patients with stage III gast...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.072017.03
更新日期：2018-01-01 00:00:00
abstract：AIM:To examine the kinds of changes parents would like to see in those settings where children spend time (kindergartens and schools, child care centres and after-school care facilities, and the local neighbourhood) in policies and practices that impact on children's risk of obesity, and to establish whether parents mi...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Enteral nutrition (EN) plays a vital role in promoting the recovery of patients after surgery. This study aims to clarify the effects of total protein enteral nutrition (TPEN) and short peptide enteral nutrition (SPEN) on the recovery of patients after radical gastrectomy. METHODS AND STUDY D...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.202007_29(2).0005
更新日期：2020-01-01 00:00:00
abstract：:Stress and malnutrition are associated with altered body composition. Extracellular fluid increases, with wt gain, but in response to stress BCM may gradually shrink with wt loss. In catabolic illness there is extracellular fluid expansion and erosion of AT and BCM. In stress, net loss of body fat was associated with ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:The Asia-Pacific region was on track to achieve the Millennium Development Goal of halving the prevalence of extreme poverty by 2015, but recent dramatic rises in the price of rice and other staples have pushed millions of people back into hunger and poverty. This indicates that the region's food supply system is more...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Human milk has nutritional, protective, and developmental advantages for premature infants. However, proteomic information of low abundant protein of donor milk is insufficient. The purpose of this study is to analyze and compare the proteome of low abundant protein of donor milk obtained at d...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.032017.16
更新日期：2018-01-01 00:00:00
abstract：:The study was undertaken to assess the prevalence of obesity in Taiwanese aborigines and to identify the associated factors. Data for this study were from the "2001 National Health Interview Survey (NHIS)" that conducted in-home, face-to-face, interviews on 6,592 households (26,658 persons) of a national probability s...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:The present study was undertaken in two backward districts namely Phulbani and Sundargarh, of Orissa State, India, to study operational aspects of the distribution programme of iron fortified salt (IFS), and the extent of any overlap with the ongoing National Nutritional Anaemia Control Programme (NNACP) and possible ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:The Malaysian government recently introduced a ban on fast food advertisements targeting children on television. This study reports on data covering 6 months of television food advertising targeting children. Six out of seven of the Nation's commercial television networks participated (response rate = 85.7%). Based on...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:A computer system, called SERVE-NZ Nutririon Management System, for use in diabetes management, addresses the problem of concurrently controlling postprandial glycaemic response and nutrient intake in meals containing a number of foods, is described. It converts the weight and relative glycaemic potency of each food t...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2000.00146.x
更新日期：2000-06-01 00:00:00
abstract：:Activation of the NO-cGMP pathway is associated with myocardial protection against ischemia. During ischemia, function of this pathway is disturbed. Little is known about the effects of supplements such as Red Palm Oil (RPO) on the myocardial NO- cGMP- signalling pathway. RPO consists of saturated (SFAs), mono-unsatur...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：:Evidence indicates that dietary trans fatty acids (TFA) obtained from partially hydrogenated vegetable oils (PHVO) increase the risk of coronary heart disease (CHD). Studies have implicated TFA in increasing the risk and incidence of diabetes. Furthermore, TFA may compromise fetal and early infant growth and developme...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:There is very limited published data on Tibetan dietary patterns and its association with nutrient intakes and socioeconomic factors. The aim of this study was to identify and describe the dietary patterns and the associations with nutrient intakes in rural Tibetan pregnant, lactating mothers....
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.012016.13
更新日期：2017-05-01 00:00:00
abstract：:D-lactic acidosis is a rare complication in children with short bowel syndrome. It results from fermentation of dietary carbohydrate by luminal bacteria in the small bowel caused by bacterial overgrowth. We present the case of a 14-year-old boy who had been diagnosed with short bowel syndrome from surgical treatment o...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Cultural and/or environmental barriers make the assessment of dietary intake in rural populations challenging. We aimed to assess the accuracy of a meal recall questionnaire, adapted for use with impoverished South Indian populations living in rural areas. METHODS AND STUDY DESIGN:Dietary dat...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2016.25.1.19
更新日期：2016-01-01 00:00:00
abstract：:Our aim has been to construct a portable prototype instrument for measuring the whole body composition in vivo of growing lambs in terms of fat. protein and water by determining the mass of carbon, nitrogen and oxygen present. A small and compact sealed tube neutron generator which has the capability of exploiting the...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Recent studies have analyzed dietary patterns to assess overall dietary habits, but there have been no studies of dietary patterns among the contemporary Japanese population nationwide. The objective of this study was to identify dietary patterns based on consumption of food items among Japane...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.042018.06
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Short bowel syndrome (SBS) is a rare and life-threatening disease. Few studies have investigated risk factors for parenteral nutrition (PN)-dependence and death in SBS. Accordingly, the aim of this study was to investigate the risk factors for PN-dependence and long-term mortality in SBS. MET...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.102017.03
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Data suggest that genetic factors are associated with BMI. The fat mass and obesity- associated (FTO) gene modulates adipogenesis through alternative splicing and m6A demethylation. Individuals with FTO rs9939609 gene polymorphism have a preference for energy-dense foods. This study investigat...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.201903_28(1).0024
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:A key measure for classifying bacteria as a probiotic is the ability to survive gastric transport and be recoverable in faeces. The aim of this study was to determine whether Lactobacillus casei strain Shirota (LcS) could be recovered in the faeces of healthy young Australian adults following ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 临床试验,杂志文章
doi：10.6133/apjcn.201912_28(4).0009
更新日期：2019-01-01 00:00:00
abstract：:It is important to elucidate the dietary factors contributing to the development of metabolic syndrome among middle-aged women to better prevent and manage the syndrome. The objective was to determine the relationship between dietary intake and metabolic syndrome in urban Babolian middle-aged women. Systematic random ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Obesity has become a public health problem and is a cause of some preventable illnesses. Among several methods for treating obesity, the use of food supplements is highly common. A commonly used food supplement is green coffee bean extract. The objective of this study was to evaluate the effic...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：10.6133/apjcn.022017.03
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Universal salt iodization (USI) was introduced in China in 1995, but whether the iodine status is optimal is questionable. This study was conducted to assess the iodine nutrition among Zhejiang population in coastal regions in China. METHODS:A cross-sectional survey for iodine nutritional status was conduct...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2015.24.2.08
更新日期：2015-01-01 00:00:00
