Tenecteplase to treat pulmonary embolism in the emergency department.

abstract：:On stimulation of platelets with agonists, for example, thrombin, a rapid rise in intracellular pH is observed. This alkalinization is mediated by an increase in transport activity of the Na(+)/H(+) exchanger isoform NHE1. In addition to this Na(+)/H(+) exchange mechanism, platelets express bicarbonate/chloride exchan...

journal_title：Journal of thrombosis and thrombolysis

authors： Rosskopf D

更新日期：1999-07-01 00:00:00

abstract：:Warfarin is the most widely prescribed oral anticoagulant, but large interindividual variations exist in the dose required to achieve comparable therapeutic effects. Several clinical and genetic variables have been identified that influence warfarin dosing. However, interactions between genotype and nutrition remain u...

journal_title：Journal of thrombosis and thrombolysis

authors： Saito R,Takeda K,Yamamoto K,Nakagawa A,Aoki H,Fujibayashi K,Wakasa M,Motoyama A,Iwadare M,Ishida R,Fujioka N,Tsuchiya T,Akao H,Kawai Y,Kitayama M,Kajinami K

更新日期：2014-07-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening thrombotic microangiopathy caused by severely reduced activity of the von-Willebrand factor-cleaving protease ADAMTS13, mainly caused by anti-ADAMTS-13 antibodies. Although several test systems for ADAMTS13 measurement exist, long turn-around times hamper...

journal_title：Journal of thrombosis and thrombolysis

authors： Stratmann J,Ward JN,Miesbach W

更新日期：2020-10-01 00:00:00

abstract：:Moderate use of alcohol has shown protective effects in coronary artery disease, while excessive use has been associated with cardiomyopathy and hypertension. Since alcohol is a vasodilator, we postulated that it might have protective effects when administered acutely in the setting of ischemia/reperfusion. Therefore,...

journal_title：Journal of thrombosis and thrombolysis

authors： Bellows SD,Hale SL,Kloner RA

更新日期：1996-01-01 00:00:00

abstract：:One of the major mechanisms of action of chemo-radiation is to induce cellular senescence, which exerts crucial roles in age-related pathology. The concept of senescence is evolved, and the novel understanding of senescence-associated reprogramming/stemness has emerged. This new concept emphasizes senescence as not on...

journal_title：Journal of thrombosis and thrombolysis

authors： Dominic A,Hamilton D,Abe JI

更新日期：2020-10-20 00:00:00

abstract：:We describe a case of a 67-year-old woman with a history of cerebral infarction and pulmonary embolism that presented with chest pain. Subsequent evaluation resulted in a diagnosis of acute myocardial infarction and occult DVT, and imaging revealed a rare congenital absence of the infra-renal portion of the inferior v...

journal_title：Journal of thrombosis and thrombolysis

authors： Takehara N,Hasebe N,Enomoto S,Takeuchi T,Takahashi F,Ota T,Kawamura Y,Kikuchi K

更新日期：2005-04-01 00:00:00

abstract：:Recent gene knockout studies on mice have shown the role of toll-like receptor 9 (TLR9) in resolution of venous thromboembolism (VTE) through sterile inflammation. However, the role of a putative functional TLR9 polymorphism (rs5743836) in risk assessment of VTE recurrence remains unknown. The aim of our study was to ...

journal_title：Journal of thrombosis and thrombolysis

authors： Ahmad A,Sundquist K,Zöller B,Svensson PJ,Sundquist J,Memon AA

更新日期：2017-07-01 00:00:00

abstract：UNLABELLED:Compression therapy is still not widely used for patients with deep vein thrombosis (DVT). This report provides information on Italian doctors' use of elastic stockings (ES) after acute DVT and identifies some predictors of prescription. MATERIAL AND METHODS:The MASTER multicenter registry collected informa...

journal_title：Journal of thrombosis and thrombolysis

authors： Arpaia G,Carpenedo M,Pistelli R,Mastrogiacomo O,Cimminiello C,Agnelli G

更新日期：2009-11-01 00:00:00

abstract：:We describe the results of a novel complete care package using point-of-care INR testing and computerized decision support for the management of oral anticoagulation by nurse-led primary care clinics in the United Kingdom. We found such therapy to be as safe and effective as traditional hospital-based care for oral an...

journal_title：Journal of thrombosis and thrombolysis

authors： Fitzmaurice DA

更新日期：2006-02-01 00:00:00

abstract：:In vascular access practices, the internal vessel size is considered important, and a catheter to vessel ratio (CVR) is recommended to assist clinicians in selecting the most appropriate-sized device for the vessel. In 2016, new practice recommendations stated that the CVR can increase from 33 to 45% of the vessels di...

journal_title：Journal of thrombosis and thrombolysis

authors： Spencer TR,Mahoney KJ

更新日期：2017-11-01 00:00:00

abstract：:The initial treatment of acute venous thrombosis using low-molecular-weight heparin (LMWH) in the outpatient setting has been shown to be feasible, effective, and safe for selected patients when compared with in-hospital treatment using continuous intravenous heparin. There will always be a significant population of p...

journal_title：Journal of thrombosis and thrombolysis

authors： Pineo GF,Hull RD

更新日期：1998-01-01 00:00:00

abstract：:Stroke and venous thromboembolism (VTE) are serious and preventable thrombotic events in patients with atrial fibrillation (AF) and who undergo surgery or hospitalization, respectively. Nevertheless, thromboprophylaxis remains greatly underused. The National Quality Forum, the Agency for Healthcare Research and Qualit...

journal_title：Journal of thrombosis and thrombolysis

authors： Eymin G,Jaffer AK

更新日期：2014-01-01 00:00:00

abstract：:To assess the effect of cessation of dual antiplatelet therapy (DAPT) regimens containing 2nd generation P2Y12 inhibitors on platelet reactivity, in patients who completed 12 months of DAPT following an acute myocardial infarction. Clinical data has shown an increased cardiovascular risk in the 90 days following cessa...

journal_title：Journal of thrombosis and thrombolysis

authors： Witberg G,Bathish J,Bental T,Leshem-Lev D,Assali A,Kornowski R,Lev E

更新日期：2018-10-01 00:00:00

abstract：:The benefits of thrombolytic therapy in the treatment of acute myocardial infarction are incontrovertible. Large-scale studies combining angiographic and clinical end-points have demonstrated a perfusion-mortality relationship, with the highest survival rate among patients with early restoration of TIMI grade 3 corona...

journal_title：Journal of thrombosis and thrombolysis

authors： Moliterno DJ,Harrington RA,Califf RM,Rapold HJ,Topol EJ

更新日期：1995-01-01 00:00:00

abstract：:Postmortem studies reported plaque erosion is frequent in young women. Recent in vivo studies failed to show age and sex differences in the plaque erosion prevalence. The aim of this study was to investigate the prevalence of plaque erosion by age and sex among acute coronary syndromes (ACS) patients. From 1699 ACS pa...

journal_title：Journal of thrombosis and thrombolysis

authors： Kim HO,Kim CJ,Kim W,Cho JM,Soeda T,Takano M,Yan BP,Crea F,Niccoli G,Vergallo R,Minami Y,Higuma T,Kimura S,Boeder NF,Nef H,Adriaenssens T,Kurihara O,Thondapu V,Russo M,Yamamoto E,Sugiyama T,Lee H,Kakuta T,Yon

更新日期：2020-04-01 00:00:00

abstract：:Thromboembolism afflicts millions of patients annually in the United States and is associated with a significant cost burden. Recent advances in oral anticoagulation have provided clinicians with more options for management of these diseases. Accordingly, regulatory, legislative, and policy-making organizations have i...

journal_title：Journal of thrombosis and thrombolysis

authors： Fanikos J,Buckley LF,Aldemerdash A,Terry KJ,Piazza G,Connors JM,Goldhaber SZ

更新日期：2015-04-01 00:00:00

abstract：:There were limited studies comparing the anterior (AC) and posterior (PC) circulation acute ischemic strokes (AIS). Our study aimed to evaluate distinct features of AC and PC strokes regarding clinical, vascular risk, pathogenesis and outcome factors after endovascular procedures. This multicenter prospective study re...

journal_title：Journal of thrombosis and thrombolysis

authors： Huo X,Raynald,Gao F,Ma N,Mo D,Sun X,Song L,Jia B,Pan Y,Wang Y,Liu L,Zhao X,Wang Y,Miao Z,ANGEL investigators.

更新日期：2020-05-01 00:00:00

abstract：:Drug-eluting stents (DES) reduce the incidence of in-stent restenosis (ISR) after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). Whether the use of biomarkers might be of utility to identify patients who remain at risk for DES ISR after primary PCI has never been exami...

journal_title：Journal of thrombosis and thrombolysis

authors： Claessen BE,Stone GW,Mehran R,Witzenbichler B,Brodie BR,Wöhrle J,Witkowski A,Guagliumi G,Zmudka K,Henriques JP,Tijssen JG,Sanidas EA,Chantziara V,Hakim D,Leon S,Xu K,Dangas GD

更新日期：2012-08-01 00:00:00

abstract：:Heparin induced thrombocytopenia (HIT) is a life and limb-threatening complication of heparin exposure. The misdiagnosis of this disease can have major consequences on the patients. The objective of this study was to evaluate a diagnostic strategy that combines the 4Ts score with the result of HemosIL® AcuStar HIT-IgG...

journal_title：Journal of thrombosis and thrombolysis

authors： Marashi-Sabouni Z,Vayne C,Ibrahim-Kosta M,Guidon C,Loundou A,Guery EA,Morange PE,Camoin-Jau L

更新日期：2021-01-01 00:00:00

abstract：:The predictive value of and the influencing factors associated with early neurological improvement (ENI) among patients with acute basilar artery occlusion (BAO) have not been well studied. The present study aimed to evaluate whether ENI predicted a better functional outcome and to identify the influencing factors of ...

journal_title：Journal of thrombosis and thrombolysis

authors： Sun X,Zhang H,Tong X,Gao F,Deng Y,Ma G,Ma N,Mo D,Song L,Liu L,Huo X,Miao Z

更新日期：2021-01-01 00:00:00

abstract：:The exact relationship between primary percutaneous coronary intervention (PCI) volume and mortality remains unclear. No data are available on how this relationship could be affected by time-to-presentation. The primary aim of this study was to evaluate the impact of hospital primary PCI volume on in-hospital mortalit...

journal_title：Journal of thrombosis and thrombolysis

authors： Navarese EP,De Servi S,Politi A,Martinoni A,Musumeci G,Boschetti E,Belli G,D'Urbano M,Piccaluga E,Lettieri C,Klugmann S

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:To describe and compare warfarin therapy use and outcomes between warfarin-receiving patients in hospice or palliative care (HPC) and not in HPC. METHODS:This retrospective, matched analysis examined warfarin-receiving patients who did (study cohort) and did not receive (control cohort) HPC services between 20...

journal_title：Journal of thrombosis and thrombolysis

authors： Hill RR,Martinez KD,Delate T,Witt DM

更新日期：2009-04-01 00:00:00

abstract：:Differences in genetic makeup or polymorphisms can affect individual drug response. Detecting genetic variation may help predict how a patient will respond to a drug and could be used as a tool to select optimal therapy, tailor dosage regimens, and improve clinical outcomes. The data are replete relative to the therap...

journal_title：Journal of thrombosis and thrombolysis

authors： Cambria-Kiely JA,Gandhi PJ

更新日期：2002-08-01 00:00:00

abstract：:The home prothrombin time/international normalized ratio (PT/INR) self-management could be convenient for patients, enhancing treatment compliance and improving the quality of the oral anticoagulation. However, patient self-management (PSM) of oral anticoagulation may not be feasible for up to half of the patients due...

journal_title：Journal of thrombosis and thrombolysis

authors： da Silva Saraiva S,Orsi FA,Santos MP,Machado T,Montalvão S,Costa-Lima C,de Paula EV,Colella MP,Annichino-Bizzacchi J

更新日期：2016-07-01 00:00:00

abstract：:A main underlying pathology of coronary artery disease is the deposition of cholesterol in the arteries supplying blood to the heart that leads to stenosis and myocardial infarction. We tested if dyslipidemia is a risk factor for coronary artery disease in the Lebanese population, and studied the role of the total cho...

journal_title：Journal of thrombosis and thrombolysis

authors： Platt DE,Ghassibe-Sabbagh M,Youhanna S,Hager J,Cazier JB,Kamatani Y,Salloum AK,Haber M,Romanos J,Doueihy B,Mouzaya F,Kibbani S,Sbeite H,Deeb ME,Chammas E,El Bayeh H,Khazen G,Gauguier D,Zalloua PA,Abchee AB,FGENTCA

更新日期：2015-01-01 00:00:00

abstract：UNLABELLED:Coronary artery calcification may play a significant role in the pathophysiology of plaque progression and healing. We hypothesized that osteoprotegerin, an inhibitor of osteoclastogenesis, may participate in the calcification of coronary plaques or the response to injury after coronary stenting. A prospecti...

journal_title：Journal of thrombosis and thrombolysis

authors： Gogo PB Jr,Schneider DJ,Terrien EF,Sobel BE,Dauerman HL

更新日期：2006-12-01 00:00:00

abstract：:The concept of a pulmonary embolism response team (PERT) is multidisciplinary, with the hope that it may positively impact patient care, hospital efficiency, and outcomes in the treatment of patients with intermediate and high risk pulmonary embolism (PE). Clinical characteristics of a baseline population of patients ...

journal_title：Journal of thrombosis and thrombolysis

authors： Wright C,Elbadawi A,Chen YL,Patel D,Mazzillo J,Acquisto N,Groth C,Van Galen J,Delehanty J,Pietropaoli A,Trawick D,James White R,Cameron P,Gosev I,Barrus B,Kumar NG,Cameron SJ

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Venous thromboembolism (VTE) is a significant cause of mortality and morbidity in medical patients. Although thromboprophylaxis with enoxaparin reduces the risk of VTE in these patients, the optimal duration of therapy is not currently known. The EXCLAIM (EXtended CLinical prophylaxis in Acutely Ill Medical ...

journal_title：Journal of thrombosis and thrombolysis

authors： Hull RD,Schellong SM,Tapson VF,Monreal M,Samama MM,Turpie AG,Wildgoose P,Yusen RD

更新日期：2006-08-01 00:00:00

abstract：:Since the reports by Weismann and Tobin in 1958 and Roberts et al. in 1964 called attention to paradoxical thrombosis in patients treated with heparin, the thrombotic aspect of the heparin-induced thrombocytopenia syndrome (HIT) has been emphasized. Yet to this day, the mechanism of thrombosis associated with HIT (HIT...

journal_title：Journal of thrombosis and thrombolysis

authors： Walenga JM,Jeske WP,Messmore HL

更新日期：2000-11-01 00:00:00

abstract：:While outpatient anticoagulation services (AMS) have existed extensively for a number of years, inpatient AMS have only recently begun to be implemented on a widespread basis. This is in direct response to anticoagulation regulations set forth by entities such as the Joint Commission (TJC) and the Centers for Medicare...

journal_title：Journal of thrombosis and thrombolysis

authors： Burnett A,D'Angio R,Earl LE,Garcia D

更新日期：2011-04-01 00:00:00