Cystic fibrosis in adults: an overview for the internist.

abstract：:Anticonvulsant hypersensitivity syndrome, a potentially fatal but rare reaction, manifests as rash, fever, tender lymphadenopathy, hepatitis, and eosinophilia. To manage hypersensitivity syndrome successfully, one must recognize the symptoms early, stop the offending drug immediately, and substitute a safe, alternativ...

journal_title：Cleveland Clinic journal of medicine

authors： Hamer HM,Morris HH

更新日期：1999-04-01 00:00:00

abstract：:The Women's Health Initiative found that the risks of hormone replacement therapy (HRT) exceeded its benefits in a large group of older postmenopausal women, but did not consider the efficacy of HRT in relieving vasomotor symptoms. Another recent study found that low-dose HRT was as effective as standard-dose HRT whil...

journal_title：Cleveland Clinic journal of medicine

authors： Thacker HL

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Mediastinal extension of pancreatic pseudocysts has caused rare cases of cardiac compression, but to our knowledge, congestive heart disease due to cardiac compression by a pancreatic pseudocyst has never been reported. SUMMARY:A 48-year-old man presented with dyspnea, swelling of both lower limbs, left-sid...

journal_title：Cleveland Clinic journal of medicine

authors： Lee FY,Wang YT,Poh SC

更新日期：1994-03-01 00:00:00

abstract：:The treatment of hepatitis C has evolved rapidly since the identification of the hepatitis C virus (HCV) in 1989. Since the first accepted therapy for HCV infection, recombinant interferon, received marketing approval a little more than a decade ago, it has come to be used in combination with ribavirin for improved ra...

journal_title：Cleveland Clinic journal of medicine

authors： Saadeh S,Davis GL

更新日期：2004-05-01 00:00:00

abstract：:Women with heart failure differ from their male counterparts in a number of ways, including etiology, pattern of cardiac remodeling, and prognosis. They may even respond differently to medical therapy. But until prospective, sex-specific studies show that we should do otherwise, we recommend that women with heart fail...

journal_title：Cleveland Clinic journal of medicine

authors： Mezu U,Bott-Silverman C,Hsich E

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Nicotinic acid, widely used to lower serum cholesterol levels, may rarely cause cholestatic jaundice. SUMMARY:A 61-year-old white man with hypercholesterolemia complained of marked pruritus and became jaundiced after taking 3.0 g of crystalline nicotinic acid daily for 13 months. His total serum bilirubin l...

journal_title：Cleveland Clinic journal of medicine

authors： Patel SD,Taylor HC

更新日期：1994-01-01 00:00:00

abstract：:Increased levels of human growth hormone (HGH) may correlate with the severity of psoriasis and native somatostatin (SRIF) may improve it by inhibiting HGH release. The synthetic SRIF analog, SMS 201-995, is a potent and long-lasting HGH inhibitor. Nine patients with chronic plaque psoriasis completed 12 weeks of open...

journal_title：Cleveland Clinic journal of medicine

authors： Camisa C,O'Dorisio TM,Maceyko RF,Schacht GE,Mekhjian HS,Howe BA

更新日期：1990-01-01 00:00:00

abstract：:Obesity is epidemic and dangerous. Weight loss is difficult but worth the effort. Although new weight-loss drugs are available, there are no magic bullets: to lose weight and keep it off, people must eat less and exercise more. This article presents a practical approach on how physicians can help their patients lose w...

journal_title：Cleveland Clinic journal of medicine

authors： Weiss D

更新日期：2000-10-01 00:00:00

abstract：:Lifestyle modifications in conjunction with antidiabetes medications can produce near-normal blood glucose concentrations in patients with type 2 diabetes mellitus (T2DM). Because these patients have increased cardiovascular morbidity and mortality, treatment strategies should also address the cardiovascular aspects o...

journal_title：Cleveland Clinic journal of medicine

authors： Peters AL

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Coronary artery disease is a major cause of death in transplant recipients. PURPOSE:To review current approaches for the detection, evaluation, and treatment of coronary artery disease in transplant recipients. SUMMARY:Renal transplantation promotes the development of coronary artery disease primarily beca...

journal_title：Cleveland Clinic journal of medicine

authors： Braun WE,Marwick TH

更新日期：1994-09-01 00:00:00

abstract：:Focal acantholytic dyskeratosis consistent with the clinical and histological features of Darier's type of transient acantholytic dermatosis occurred in a man with myelodysplasia. Topical steroids and systemic antihistamines provided temporary and moderate relief from pruritus, but failed to control the dermatosis. ...

journal_title：Cleveland Clinic journal of medicine

authors： Rockley PF,Bergfeld WF,Tomecki KJ,Brydon JK

更新日期：1990-09-01 00:00:00

abstract：:Obesity is associated with higher rates of death due to cancer. Possible explanations for this association include physiological factors associated with obesity, lower cancer screening rates in obese people, and technical difficulties in treating obese patients. These problems represent opportunities to improve the ca...

journal_title：Cleveland Clinic journal of medicine

authors： Bordeaux BC,Bolen S,Brotman DJ

更新日期：2006-10-01 00:00:00

abstract：:Much scientific and anecdotal data demonstrate favorable metabolic responses to very-low-carbohydrate diets. We believe that very-low-carbohydrate diets merit further study for weight loss, and that criticisms of these diets lack scientific evidence. ...

journal_title：Cleveland Clinic journal of medicine

authors： Volek JS,Westman EC

更新日期：2002-11-01 00:00:00

abstract：:Cyclospora cayetanensis, an emerging pathogen with worldwide distribution, causes diarrhea in both immunocompetent and HIV-infected patients. We review the epidemiology of Cyclospora infection and how to diagnose and treat it. ...

journal_title：Cleveland Clinic journal of medicine

authors： Gumbo T,Gordon SM,Adal KA

更新日期：1997-06-01 00:00:00

abstract：:Exercise, in conjunction with diet, is critical to losing weight and maintaining health in obese patients. While it can be challenging for an obese person to transition to a healthy lifestyle, the physical and emotional benefits of a regular exercise program make it worth the effort. ...

journal_title：Cleveland Clinic journal of medicine

authors： Higgins JP,Higgins CL

更新日期：2016-02-01 00:00:00

abstract：:Evidence is mounting that depression is a risk factor for the development of cardiovascular disease and portends a worse outcome in cardiac patients. Depression can be easily diagnosed and safely treated in cardiac patients, but it is undertreated. ...

journal_title：Cleveland Clinic journal of medicine

authors： Kemp DE,Malhotra S,Franco KN,Tesar G,Bronson DL

更新日期：2003-09-01 00:00:00

abstract：:Newer theories suggest that patients with fibromyalgia have a biologic predisposition to perceiving pain with more sensitivity than people without fibromyalgia. Several biologic triggers are implicated as possibly initiating or worsening the symptoms of fibromyalgia. Treatments to manage pain, help with sleep, and, wh...

journal_title：Cleveland Clinic journal of medicine

authors： Clauw DJ

更新日期：2001-10-01 00:00:00

abstract：:Recommendations exist for preparticipation physical examinations, but there is no national standard, and the recommendations are not widely followed. The most common reasons for denying clearance to play are musculoskeletal conditions, hypertension, and visual acuity problems. Although detecting potentially life-threa...

journal_title：Cleveland Clinic journal of medicine

authors： Mick TM,Dimeff RJ

更新日期：2004-07-01 00:00:00

abstract：:Studies published during the past year on the treatment of several infectious diseases provide valuable information that should enable us to treat our patients more effectively. Among those findings: Oral vancomycin (Vancocin) is superior to oral metronidazole (Flagyl) for treating patients with severe Clostridium dif...

journal_title：Cleveland Clinic journal of medicine

authors： Longworth DL

更新日期：2008-08-01 00:00:00

abstract：:Coronary artery disease is different in women than in men in its pathogenesis, symptoms, and prognosis. Needed is a strategy for detecting and assessing coronary disease specifically in women. This review highlights recent evidence on sex differences in coronary artery disease. ...

journal_title：Cleveland Clinic journal of medicine

authors： Bellasi A,Raggi P,Merz CN,Shaw LJ

更新日期：2007-08-01 00:00:00

abstract：:The focus of palliative care is to alleviate pain and suffering for patients, potentially while they concurrently pursue life-prolonging or curative therapy. The potential breadth of palliative care is recognized by the Medicare program, but the Medicare hospice benefit is narrowly defined and limited to care that is ...

journal_title：Cleveland Clinic journal of medicine

authors： Labson MC,Sacco MM,Weissman DE,Gornet B,Stuart B

更新日期：2013-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is an important cause of death in patients with liver disease, and its incidence appears to be rising in the United States. Because early diagnosis improves the chances of survival, it is important to identify patients who would benefit from surveillance. Once HCC is suspected on surveil...

journal_title：Cleveland Clinic journal of medicine

authors： Murali AR,Romero-Marrero C,Aucejo F,Menon KV

更新日期：2013-10-01 00:00:00

abstract：:Thirty-four young patients (28 male and 6 female) underwent aortic valve replacement between 1972 and 1988. Ages ranged from 11 to 20 years (mean 17.7 years). Including reimplantation in the follow-up period, 40 valves were implanted, among which were 17 (43%) St. Jude, 7 (16%) Bjork-Shiley, and 4 (10%) Carpentier-Edw...

journal_title：Cleveland Clinic journal of medicine

authors： Moodie DS,Hanhan U,Sterba R,Murphy DJ Jr,Rosenkranz ER,Kovacs AM

更新日期：1992-09-01 00:00:00

abstract：:Interleukin 1 (IL-1) is a potential target of therapy in COVID-19 during the severe respiratory-inflammatory phase ("cytokine release syndrome"), when pulmonary macrophages are hyperactivated, releasing IL-1 and other cytokines. Preliminary evidence indicates that anakinra and canakinumab, drugs that block the action ...

journal_title：Cleveland Clinic journal of medicine

authors： Calabrese LH,Calabrese C

更新日期：2020-07-09 00:00:00

abstract：:Up to two-thirds of patients who have had a stroke have obstructive sleep apnea (OSA) afterward. These patients have worse outcomes than those without OSA in terms of short-term morbidity, functional and cognitive recovery, and mortality rates over the long term. Following a stroke, identifying OSA and treating it wit...

journal_title：Cleveland Clinic journal of medicine

authors： McKee Z,Auckley DH

更新日期：2019-06-01 00:00:00

abstract：:Glomerulonephritis (GN) is a common manifestation of the antineutrophil cytoplasmic antibody-associated systemic vasculitides (AASV), which include granulomatosis with polyangiitis and microscopic polyangiitis. The level of renal involvement at presentation is highly predictive of survival and should be assessed early...

journal_title：Cleveland Clinic journal of medicine

authors： de Groot K

更新日期：2012-11-01 00:00:00

abstract：:Evidence of a neurophysiologic mechanism that involves hormones from adipocytes, pancreatic islet cells, and the gastrointestinal tract implicated in both obesity and diabetes has led to a search for drugs that not only either target obesity and diabetes or reduce hemoglobin A1c, but also have weight loss as a potenti...

journal_title：Cleveland Clinic journal of medicine

authors： Esquivel MA,Lansang MC

更新日期：2017-07-01 00:00:00

abstract：:Treatment of anemia in the perioperative period of major orthopedic surgery decreases the need for blood transfusion and improves perioperative outcomes. Use of epoetin alfa in this setting is FDA-approved and provides significant benefit to qualified and carefully chosen patients. ...

journal_title：Cleveland Clinic journal of medicine

authors： Kumar A,Dimov V

更新日期：2006-09-01 00:00:00

abstract：:During a 10-year period, 60 patients with confirmed diagnoses of pheochromocytoma underwent a total of 63 surgical procedure. To control extreme blood pressure elevations, 6 patients received phenoxybenzamine preoperatively and 28 patients received prazosin. The remaining 29 patients received neither drug. Intravenous...

journal_title：Cleveland Clinic journal of medicine

authors： Boutros AR,Bravo EL,Zanettin G,Straffon RA

更新日期：1990-10-01 00:00:00

abstract：:Intravascular ultrasonography (IVUS) can precisely measure plaque burden and is being used to test new drug therapies. Other imaging tests may also prove useful to monitor treatment of atherosclerosis and identify populations at risk for coronary artery disease (CAD). ...

journal_title：Cleveland Clinic journal of medicine

authors： Schoenhagen P,Nissen SE

更新日期：2005-06-01 00:00:00