Differential expression of genes encoding tight junction proteins in colorectal cancer: frequent dysregulation of claudin-1, -8 and -12.

abstract：:Between 1979 and 1989, 169 patients had a curative operation for right sided colonic cancer. A retrospective analysis of the incidence and degree of lymph node metastasis was performed in all and survival rate was determined in 144 patients who could be followed over a period of 5 years or more. In all patients, disse...

journal_title：International journal of colorectal disease

authors： Tagliacozzo S,Tocchi A

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIMS:The advent of contrast-enhanced ultrasound (CEUS) has called into question the efficacy of standard ultrasonographic techniques. In this study, we evaluated B-mode and color-duplex imaging and CEUS in the detection of liver metastases, using intraoperative and histological findings as a reference. MATE...

journal_title：International journal of colorectal disease

authors： Konopke R,Kersting S,Bergert H,Bloomenthal A,Gastmeier J,Saeger HD,Bunk A

更新日期：2007-02-01 00:00:00

abstract：INTRODUCTION:Cancer survival is related not only to primary malignancy but also to concomitant nonmalignant diseases. The aim of this study was to investigate the prognostic capacity of four comorbidity indices [the Charlson comorbidity index (CCI), the Elixhauser method, the National Institute on Aging (NIA) and Natio...

journal_title：International journal of colorectal disease

authors： Marventano S,Grosso G,Mistretta A,Bogusz-Czerniewicz M,Ferranti R,Nolfo F,Giorgianni G,Rametta S,Drago F,Basile F,Biondi A

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:The UK government target expects all suspected colorectal cancer (CRC) patients to be seen within the Two-Week Referral (TWR) system made by general practitioners. These guidelines originally derived from only level 5 evidence. However, this has significant impact on the workload for colorectal surgeons. The ai...

journal_title：International journal of colorectal disease

authors： Padwick RT,Bajwa AA,Shaw A,Leung E,Francombe J,Stellakis ML

更新日期：2013-11-01 00:00:00

abstract：:Although scintigraphic pelvic pouch emptying scans have been used to evaluate neorectal function in patients who have undergone colectomy, mucosal proctectomy, and ileoanal pouch anastomosis, previous reports have not documented the reliability of this test in measuring pouch volume and emptying. Thus, this study was ...

journal_title：International journal of colorectal disease

authors： Woolfson K,McLeod RS,Walfisch S,Yip K,Cohen Z

更新日期：1991-02-01 00:00:00

abstract：PURPOSE:This study evaluates the erectile function of male patients treated by preoperative radiotherapy followed by surgery and surgery alone for locally advanced rectal cancer. METHODS:A total of 112 men treated by total mesorectal excision with autonomic nerve preservation were included. Seventy-three patients were...

journal_title：International journal of colorectal disease

authors： Song PH,Yun SM,Kim JH,Moon KH

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:Use of biosutures in animal models of colonic anastomoses is associated with decreased adhesions without affecting anastomotic strength. This study aimed to evaluate the effect of biosutures on colonic anastomoses kept free of adhesions by peritoneal instillation of icodextrin 4%. METHODS:Three types of coloni...

journal_title：International journal of colorectal disease

authors： Pascual I,Fernández de Miguel G,García Arranz M,García-Olmo D

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess the effect of a structured hands-on workshop on the detection rate of obstetric anal sphincter injuries. METHODS:All physicians attending the delivery ward in our institution participated in a structured obstetric anal sphincter injury hands-on workshop developed by Dr. ...

journal_title：International journal of colorectal disease

authors： Krissi H,Aviram A,Hiersch L,Ashwal E,Eitan R,Peled Y

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Cervical vagus nerve stimulation (VNS) prevents manipulation-induced intestinal inflammation and improves intestinal transit in a mouse model of postoperative ileus (POI). Cervical VNS, however, is accompanied by cardiovascular and respiratory side effects. In view of potential clinical application, we therefor...

journal_title：International journal of colorectal disease

authors： Wolthuis AM,Stakenborg N,D'Hoore A,Boeckxstaens GE

更新日期：2016-02-01 00:00:00

abstract：:This study evaluated outcome in patients undergoing laparoscopically assisted sigmoid resection for diverticular disease. A total of 29 consecutive patients were treated surgically for colonic diverticulitis; in 27 of these laparoscopy was performed. The review of medical records from a control group of 34 patients un...

journal_title：International journal of colorectal disease

authors： Köhler L,Rixen D,Troidl H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND AIMS:This study used postoperative defecography to characterize morphological features of defecatory disorders in patients following rectal resection. We also evaluated differences in dynamic defecatory condition depending on reconstruction methods for sphincter-saving surgery. MATERIALS AND METHODS:Sub...

journal_title：International journal of colorectal disease

authors： Morihiro M,Koda K,Seike K,Miyauchi H,Miyazaki M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Colorectal anastomoses created in a contaminated environment result in a high leakage rate. This study investigated whether using anastomotic sealants (TissuCol(®), Histoacryl(®) Flex, and Duraseal(®)) prevents leakage in a rat peritonitis model. STUDY DESIGN:Sixty-seven Wistar rats were divided into contro...

journal_title：International journal of colorectal disease

authors： Wu Z,Vakalopoulos KA,Boersema GS,Kroese LF,Lam KH,van der Horst PH,Mulder IM,Bastiaansen-Jenniskens YM,Kleinrensink GJ,Jeekel J,Lange JF

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Acute mesenteric ischemia (AMI) is still associated with very high morbidity and mortality while the rareness and heterogeneity hamper the establishment of evidence-based guidelines. We sought to help standardize contemporary treatment by a cohort study at our tertiary center in the rising endovascular age. ME...

journal_title：International journal of colorectal disease

authors： Matthaei H,Klein A,Branchi V,Kalff JC,Koscielny A

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:Crohn's disease (CD) commonly recurs after surgery, and a number of patients need repeated surgery, especially smokers and those with repeated surgeries or penetrating disease. Whether infliximab prevents postsurgical recurrence in high-risk CD remains unknown. In the present pilot open-labeled study, we invest...

journal_title：International journal of colorectal disease

authors： Sakuraba A,Sato T,Matsukawa H,Okamoto S,Takaishi H,Ogata H,Iwao Y,Hibi T

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:Tumor grade is a traditional prognostic parameter in colorectal cancer. Remarkably, however, there is still no generally accepted consensus how to perform tumor grading. In this study, we systematically compared the prognostic value of traditional grading based upon histological features, that is, gland formati...

journal_title：International journal of colorectal disease

authors： Resch A,Harbaum L,Pollheimer MJ,Kornprat P,Lindtner RA,Langner C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Postoperative ileus is a significant clinical challenge lacking effective management strategies. Ghrelin-receptor stimulation has promotility effects in the upper and lower gastrointestinal tract. OBJECTIVE:This proof-of-concept, phase 2, randomized study evaluated the safety and efficacy of the ghrelin-rec...

journal_title：International journal of colorectal disease

authors： Beck DE,Sweeney WB,McCarter MD,Ipamorelin 201 Study Group.

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:The purposes of this study were to assess the working definition of a colorectal anastomotic leak among colorectal surgeons and to survey the current approach to investigation and management of a patient with a suspected anastomotic leak. METHODS:Online survey consisting of nine questions regarding the definit...

journal_title：International journal of colorectal disease

authors： Adams K,Papagrigoriadis S

更新日期：2013-07-01 00:00:00

abstract：UNLABELLED:The long-term role of laparoscopy in the treatment of rectal cancer is still controversial. The aim of the present study was to evaluate the safety, the feasibility, the perioperative outcome, and the long-term results of laparoscopic total mesorectal excision (TME) for extraperitoneal rectal cancer consider...

journal_title：International journal of colorectal disease

authors： Martellucci J,Bergamini C,Bruscino A,Prosperi P,Tonelli P,Todaro A,Valeri A

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:Inflammation is an important driver of abdominal pain in inflammatory bowel disease (IBD). However, some patients in remission still experience pain. We aimed to identify risk factors associated with abdominal pain in quiescent IBD (QP-IBD) and to characterize differences from patients with active disease ex...

journal_title：International journal of colorectal disease

authors： Coates MD,Johri A,Gorrepati VS,Maheshwari P,Dalessio S,Walter V,Stuart A,Koltun W,Bernasko N,Tinsley A,Williams ED,Clarke K

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the clinical presentation, diagnosis and management of patients with intussusception, with special regard to the duration of symptoms, referral from other hospitals, outcome and complications related to delayed diagnosis. METHODS:This retrospective study was performed usin...

journal_title：International journal of colorectal disease

authors： Lehnert T,Sorge I,Till H,Rolle U

更新日期：2009-10-01 00:00:00

abstract：:Cryosurgery is one of the palliative treatment options to decrease local symptoms due to rectal carcinoma. A total of 106 patients (aged 45-92 years) underwent palliative cryosurgery for primary rectal cancer. Inclusion criteria were prohibitive surgical risk, unresectability, distant metastases, patient refusal of su...

journal_title：International journal of colorectal disease

authors： Meijer S,Rahusen FD,van der Plas LG

更新日期：1999-08-01 00:00:00

abstract：PURPOSE:In patients with advanced lower rectal cancer, the complex pelvic anatomy renders lateral pelvic lymph node dissection to be challenging. Therefore, we evaluated the utility of printing a three-dimensional (3D) pelvic model for lateral pelvic lymph node dissection. METHODS:We included 22 patients who underwent...

journal_title：International journal of colorectal disease

authors： Hojo D,Murono K,Nozawa H,Kawai K,Hata K,Tanaka T,Ishihara S

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:Aberrant activation of the Wnt/β-catenin pathway plays a major role in the development of colorectal carcinoma (CRC). Axin 2 is a key protein of this pathway and is upregulated in CRC. Here, we investigated RNA- and protein expression of axin 2 in CRC tissues at the single cell level. Moreover, the association ...

journal_title：International journal of colorectal disease

authors： Schaal U,Grenz S,Merkel S,Rau TT,Hadjihannas MV,Kremmer E,Chudasama P,Croner RS,Behrens J,Stürzl M,Naschberger E

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:The aim of this pilot study was to compare the performance and safety of the newly developed sodium phosphate (NaP) tablet (with and without laxatives) and polyethylene glycol (PEG), as bowel-cleansing regimens prior to colonoscopy. METHODS:A total of 35 patients were randomized to one of the following three g...

journal_title：International journal of colorectal disease

authors： Aihara H,Saito S,Arakawa H,Imazu H,Omar S,Kaise M,Tajiri H

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:It is controversial whether patients fare better with conservative or surgical treatment in certain stages of acute diverticulitis (AD), in particular when phlegmonous inflammation or covered micro- or macro-perforation are present. The aim of this study was to determine long-term quality of life (QoL) for AD p...

journal_title：International journal of colorectal disease

authors： Brandlhuber M,Genzinger C,Brandlhuber B,Sommer WH,Müller MH,Kreis ME

更新日期：2018-03-01 00:00:00

abstract：:Recurrence of pilonidal sinus disease after surgical intervention is not a very rare problem although sophisticated reconstruction procedures have been developed. Recurrence is thought to be related to the anatomical status of the patients, i.e., depth of the intergluteal groove. Obese patients have deeper interglutea...

journal_title：International journal of colorectal disease

authors： Cubukçu A,Gönüllü NN,Paksoy M,Alponat A,Kuru M,Ozbay O

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND AIMS:This pilot study examines whether single-dose intravenous metronidazole preoperatively is at least as effective as a broad-spectrum multi-drug regimen in preventing infection-related wound complications following excision of pilonidal sinuses with primary closure. PATIENTS AND METHODS:A double-blin...

journal_title：International journal of colorectal disease

authors： Chaudhuri A,Bekdash BA

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:There is scant data assessing the consequences of staging restorative proctocolectomy for ulcerative colitis. The aim of the study is to compare outcomes of initial vs. staged restorative proctocolectomy. METHODS:Patients completing restorative proctocolectomy, including ileostomy reversal, during 2006-2012 we...

journal_title：International journal of colorectal disease

authors： Gu J,Stocchi L,Ashburn J,Remzi FH

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) of the rectum are rarely found, and radical surgery such as abdominoperineal resection would be necessary for large rectal GIST. On the other hand, therapy for GIST has changed significantly with the use of imatinib. Neoadjuvant imatinib therapy may reduce tumor size a...

journal_title：International journal of colorectal disease

authors： Fujimoto Y,Akiyoshi T,Konishi T,Nagayama S,Fukunaga Y,Ueno M

更新日期：2014-01-01 00:00:00

abstract：:The biomechanical properties and intestinal wall composition of left colon were studied in 4-month-old, 14-month-old, and 27-month-old male rats. The hydroxyproline content and hydroxyproline concentration in old rats were increased by 36% and 26%, respectively, compared with young rats and by 20% and 17%, respectivel...

journal_title：International journal of colorectal disease

authors： Christensen H,Andreassen TT,Oxlund H

更新日期：1992-06-01 00:00:00