Complementary and alternative medicine and gastrointestinal diseases.

abstract：:In spite of expanding knowledge of cellular and molecular mechanisms of intestinal inflammation, the etiology and pathogenesis of inflammatory bowel disease (IBD) remain obscure. The link between the environment and IBD is still circumstantial, but definite progress is occurring in defining genetic susceptibility loci...

journal_title：Current opinion in gastroenterology

authors： Katz JA,Itoh J,Fiocchi C

更新日期：1999-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Cholangiocarcinoma (CCA) are heterogeneous tumors that arise from the malignant transformation of cholangiocytes along the biliary tree. CCA heterogeneity occurs at multiple levels and results in resistance to therapy and poor prognosis. Here, we review the molecular classification of CCA by focusing ...

journal_title：Current opinion in gastroenterology

authors： Louis C,Papoutsoglou P,Coulouarn C

更新日期：2020-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Rotavirus infection is the leading cause of severe dehydrating gastroenteritis, responsible for an estimated 440,000 deaths per year in children less than 5 years of age worldwide. There was great optimism when the first rotavirus vaccine was licensed in the United States in July 1998 (rhesus rotaviru...

journal_title：Current opinion in gastroenterology

authors： Bines JE

更新日期：2005-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To review important manuscripts published over the previous 2 years relative to sphincter of Oddi dysfunction (SOD). RECENT FINDINGS:The long-term outcomes of the Evaluating Predictors and Interventions of SOD (EPISOD) trial further substantiated results from the initial EPISOD study, reinforcing tha...

journal_title：Current opinion in gastroenterology

authors： Hyun JJ,Kozarek RA

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Food addiction has been implicated as a putative causal factor in chronic overeating, binge eating, and obesity. The concept of food addiction has been controversial historically due to definitional and conceptual difficulties and to a lack of rigorous scientific data. RECENT FINDINGS:Support for the...

journal_title：Current opinion in gastroenterology

authors： Corsica JA,Pelchat ML

更新日期：2010-03-01 00:00:00

abstract：:Recently, much progress has been made in the field of tumor immunology. Much of this work has focused on understanding and exploiting the innate immune response to tumor cells. A novel human receptor-ligand system that mediates natural killer (NK) and gammadelta T-cell killing of carcinoma cells has been identified, a...

journal_title：Current opinion in gastroenterology

authors： Golby SJ,Spencer J

更新日期：2001-11-01 00:00:00

abstract：:The treatment of inflammatory bowel disease is a continually evolving area and a major focus of the current literature in gastroenterology. As further information is gained in the areas of etiology, pathophysiology, and natural history of the disease, new agents are developed, and management strategies are revised. Th...

journal_title：Current opinion in gastroenterology

authors： Nash CL,Sutherland LR

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The introduction of novel molecular imaging modalities that can not only define disease states on the basis of structural changes and morphology, but also allow in-vivo visualization and characterization of molecular and biochemical alterations on a cellular level add a new dimension to our current di...

journal_title：Current opinion in gastroenterology

authors： Atreya R,Neurath MF

更新日期：2014-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Virulence factors are related to the ability of a microbe to induce disease. True virulence factors must therefore have a disease association, an in-vivo correlate with disease such as increased mucosal inflammation, or both. RECENT FINDINGS:The cytotoxin-associated gene pathogenicity island; the out...

journal_title：Current opinion in gastroenterology

authors： Lu H,Yamaoka Y,Graham DY

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Eosinophilic colitis is a rare condition, with a prevalence rate in the USA of 2-3/100 000 persons (0.003%), but diagnosed in 0.1% of biopsies in those colonoscoped for diarrhoea. Secondary colonic eosinophilia is more common and associated with systemic, colonic and infectious diseases. In this revie...

journal_title：Current opinion in gastroenterology

authors： Walker MM,Potter MD,Talley NJ

更新日期：2019-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Research in celiac disease is unraveling new findings at a high rate, and major advances seem to occur in all areas such as genetics, environmental factor, pathophysiology, and even prospective therapeutic implications. RECENT FINDINGS:New insight is being gained into the interplay between genetic an...

journal_title：Current opinion in gastroenterology

authors： Guandalini S,Setty M

更新日期：2008-11-01 00:00:00

abstract：:Over the last year, several interesting studies have been published on the treatment of esophageal carcinoma. Surprisingly, none of them was a randomized phase III trial. The debate on the necessary extent of a potentially curative surgical resection is ongoing. After initially disappointing results, the innovative te...

journal_title：Current opinion in gastroenterology

authors： van Lanschot JJ,González González D,Richel DJ

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To critically appraise evidence on probiotic use for prevention and treatment of diarrhea in children and adults. RECENT FINDINGS:Several randomized controlled trials and meta-analyses suggested that probiotics are effective in primary and secondary prevention of gastroenteritis and its treatment. Se...

journal_title：Current opinion in gastroenterology

authors： Guarino A,Lo Vecchio A,Canani RB

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Recently, a new class of intracellular pattern recognition receptors belonging to the family of nucleotide binding and oligomerization domain (NOD)-like receptors that includes NOD1, NOD2 and IPAF has been described. These proteins are involved in recognizing bacterial components or their degradation ...

journal_title：Current opinion in gastroenterology

authors： Rescigno M,Nieuwenhuis EE

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To review evidence relating to the strength of associations that have appeared in largely observational studies, between high-dose or long-term use of proton pump inhibitor drugs and certain possibly attributable side-effects, which emerge from studies confounded by other variables. In retrospective s...

journal_title：Current opinion in gastroenterology

authors： McCarthy DM

更新日期：2010-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapy for inflammatory bowel diseases (IBD) has changed dramatically in recent years with a wider use of immunomodulators and the introduction of antitumor necrosis factor (anti-TNF) agents. This article reviews the existing data on the long-term efficacy of biologics, that is, anti-TNF agents, for ...

journal_title：Current opinion in gastroenterology

authors： Sokol H,Seksik P,Cosnes J

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Esophageal varices and Mallory Weiss syndrome are the two major esophageal bleeding disorders. Although there have been major breakthroughs in the treatment of peptic ulcer bleeding, the management of esophageal bleeding disorders remains a challenging problem. This review focuses on studies published...

journal_title：Current opinion in gastroenterology

authors： Wu JC,Chan FK

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The gastroduodenum has multiple means by which it resists injury from intrinsic and extrinsic factors, including gastric acid, nonsteroidal anti-inflammatory drugs, and Helicobacter pylori. We review recent insights into the mechanisms by which the gastroduodenum resists injury and discuss factors con...

journal_title：Current opinion in gastroenterology

authors： Nayeb-Hashemi H,Kaunitz JD

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This focused, narrative review summarizes human clinical trial data for direct-acting antimicrobials in development for the treatment of gastrointestinal infections that were published in the past 18 months (1 January 2019 to 30 June 2020). RECENT FINDINGS:Antimicrobial agents for Clostridioides diff...

journal_title：Current opinion in gastroenterology

authors： Carlson TJ,Gonzales-Luna AJ,Garey KW

更新日期：2021-01-01 00:00:00

abstract：PURPOSE OF REVIEW:According to the current paradigm, ulcerative colitis and Crohn's disease occur in genetically predisposed individuals because of dysregulated immune responses against intraluminal bacterial antigens. Data have recently accumulated supporting alternative hypotheses for the pathogenesis of inflammatory...

journal_title：Current opinion in gastroenterology

authors： Bamias G,Cominelli F

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevalence of allergic diseases continues to rise globally in developed countries. Since the initial proposal of the hygiene hypothesis, there has been increasing evidence to suggest that the intestinal microbiota, particularly during early infancy, plays a critical role in regulating immune respo...

journal_title：Current opinion in gastroenterology

authors： Russell SL,Finlay BB

更新日期：2012-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Autoimmune hepatitis (AIH) is a chronic disease characterized by a lymphocyte infiltrate in the liver. For decades, nonspecific immunosuppression has been used to limit chronic liver inflammation. The high risk of relapse, the treatments side effects, and the significant number of refractory patients ...

journal_title：Current opinion in gastroenterology

authors： Cardon A,Conchon S,Renand A

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Primary biliary cholangitis (PBC) is a rare autoimmune liver disease that increasingly is diagnosed at early stages of disease. Although survival has improved, a majority suffers from one or more symptom complexes associated with PBC. Much remains unknown about the mechanisms, significance, or effecti...

journal_title：Current opinion in gastroenterology

authors： Kuo A,Kuo A,Bowlus CL

更新日期：2016-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent investigations into the regulation of pancreatic acinar cell function have led to a more detailed understanding of the mechanisms regulating digestive enzyme synthesis and secretion. This review identifies and puts into context those articles which further our understanding in this area. RECEN...

journal_title：Current opinion in gastroenterology

authors： Williams JA

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal is to review the most recent literature about biosimilars in inflammatory bowel disease (IBD), with emphasis on controversial regulatory issues. RECENT FINDINGS:Although biosimilars have been in use in Europe since 2005, the recent approval of CT-P13 (Remsima, Inflectra), a biosimilar of the...

journal_title：Current opinion in gastroenterology

authors： Gomollón F

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The human gut is the natural habitat for a large and dynamic bacterial community. There is a substantial body of evidence implicating the resident flora in the pathogenesis of chronic intestinal inflammation. This review discusses the possible role of a microbial imbalance in the pathophysiology of in...

journal_title：Current opinion in gastroenterology

authors： Guarner F

更新日期：2005-07-01 00:00:00

abstract：:Advances in cellular and molecular biology of extrahepatic cholangiocarcinoma and gallbladder adenocarcinoma are providing innovative means for the diagnosis and treatment of biliary tract cancer. Similarly, refinements in noninvasive studies--including helical computed tomography, magnetic resonance cholangiopancreat...

journal_title：Current opinion in gastroenterology

authors： Abdalla EK,Vauthey JN

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the advances in diagnostic modalities and management options for defecatory dysfunction and highlight the areas in need of further research. RECENT FINDINGS:The diagnostic utility of high-resolution anorectal manometry (ARM), which has emerged as a promising tool for the diagnosis of def...

journal_title：Current opinion in gastroenterology

authors： Neshatian L

更新日期：2018-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The most relevant studies concerning the diagnosis of esophageal varices, primary and secondary prophylaxis and treatment of variceal bleeding published in the last year are reported. RECENT FINDINGS:The specific areas reviewed are those that refer to studies on the noninvasive or minimally invasive ...

journal_title：Current opinion in gastroenterology

authors： de Franchis R,Dell'Era A

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Our objective was to review advances in bile acids in health and disease published in the last 2 years. Bile acid diarrhea (BAD) is recognized as a common cause of chronic diarrhea, and its recognition has been facilitated by development of new screening tests. RECENT FINDINGS:Primary BAD can account...

journal_title：Current opinion in gastroenterology

authors： Oduyebo I,Camilleri M

更新日期：2017-05-01 00:00:00