Review article: complete gastro-oesophageal reflux monitoring - combined pH and impedance.

abstract：:The United Network for Organ Sharing database revealed that over the last 4-5 years, an average of 1800 patients were removed from the cadaveric waiting list annually because of patients' death and an additional 400-500 were removed from the list because of the severity of their illnesses. The pre-transplant evaluatio...

journal_title：Alimentary pharmacology & therapeutics

authors： Pham PT,Pham PC,Rastogi A,Wilkinson AH

更新日期：2005-04-15 00:00:00

abstract：BACKGROUND:Recent studies in adults have shown that polymeric (whole protein) diets are as effective as semi-elemental and elemental formulae for the induction of remission in small bowel Crohn's disease. Whole protein diets are more palatable and cheaper. There have been no studies confirming efficacy in children. PA...

journal_title：Alimentary pharmacology & therapeutics

authors： Beattie RM,Schiffrin EJ,Donnet-Hughes A,Huggett AC,Domizio P,MacDonald TT,Walker-Smith JA

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Data on liver transplantation (LT) in acute on chronic liver failure (ACLF) are scanty. AIM:To perform meta-analysis on outcomes after LT for ACLF compared with ACLF patients not receiving LT or with LT recipients for indications other than ACLF. METHODS:We pooled data from 12 studies on LT outcomes among ...

journal_title：Alimentary pharmacology & therapeutics

authors： Abdallah MA,Waleed M,Bell MG,Nelson M,Wong R,Sundaram V,Singal AK

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Although enteral nutrition is a recognized form of treatment for intestinal Crohn's disease, there are persisting problems with feed palatability and only limited data as to its mode of action. AIM:To assess the effects of a specific oral polymeric diet (CT3211; Nestle, Vevey, Switzerland), which is rich in...

journal_title：Alimentary pharmacology & therapeutics

authors： Fell JM,Paintin M,Arnaud-Battandier F,Beattie RM,Hollis A,Kitching P,Donnet-Hughes A,MacDonald TT,Walker-Smith JA

更新日期：2000-03-01 00:00:00

abstract：:Studies from the Western hemisphere have established the efficacy and safety of tegaserod in women with irritable bowel syndrome and constipation. This review summarizes the results of recent studies from around the world that confirm the efficacy and safety of tegaserod, and expand our understanding of the role of th...

journal_title：Alimentary pharmacology & therapeutics

authors： Chey WD

更新日期：2004-11-01 00:00:00

abstract：:The effect of 7 days of oral dosing with 5 mg day-1 and 20 mg day-1 omeprazole on basal and pentagastrin-stimulated gastric acid output was studied in nine duodenal ulcer patients. Basal acid output measured 5-6 h post-dosing was decreased by a mean of 75% on 5 mg omeprazole and by 90% on 20 mg omeprazole (P less than...

journal_title：Alimentary pharmacology & therapeutics

authors： McLauchlan G,Crean GP,McColl KE

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Both simple proportions and statistical tests are utilised for symptom-reflux association. We systematically compared three such tests in a clinical setting. AIM:To compare the three commonly used symptom reflux association tests in a large cohort of patients undergoing ambulatory pH monitoring for the eval...

journal_title：Alimentary pharmacology & therapeutics

authors： Kushnir VM,Sathyamurthy A,Drapekin J,Gaddam S,Sayuk GS,Gyawali CP

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Peristomal wound infections are common complications of percutaneous endoscopic gastrostomy (PEG), especially in hospitals where methicillin-resistant Staphylococcus aureus (MRSA) is endemic. Evidence suggests that antibiotic prophylaxis at PEG insertion may reduce infection rates. AIM:To examine rates of p...

journal_title：Alimentary pharmacology & therapeutics

authors： Thomas S,Cantrill S,Waghorn DJ,McIntyre A

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection may persist after both first- and second-line current treatments. AIM:To assess the efficacy of a third-line, culture-guided treatment approach for the eradication of H. pylori. METHODS:Patterns of resistance were analysed in H. pylori isolates from 94 consecutive patients in ...

journal_title：Alimentary pharmacology & therapeutics

authors： Cammarota G,Martino A,Pirozzi G,Cianci R,Branca G,Nista EC,Cazzato A,Cannizzaro O,Miele L,Grieco A,Gasbarrini A,Gasbarrini G

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:CagA protein is encoded by the cagA gene, which is part of the cag pathogenicity island (PAI) in Helicobacter pylori. Insertion sequence (IS) elements are a diverse set of specialized DNA segments that can move to new sites in bacterial genomes. AIM:To determine the role of cagPAI and IS605 in the developme...

journal_title：Alimentary pharmacology & therapeutics

authors： Deguchi R,Igarashi M,Watanabe K,Takagi A

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Two variants in the organic cation transporter gene cluster have been recently reported to confer susceptibility to Crohn's disease (CD). AIM:To investigate these variants in CD and ulcerative colitis (UC), and their interaction with CARD15 gene and correlation to clinical subphenotypes. METHODS:Case-contr...

journal_title：Alimentary pharmacology & therapeutics

authors： Palmieri O,Latiano A,Valvano R,D'Incà R,Vecchi M,Sturniolo GC,Saibeni S,Peyvandi F,Bossa F,Zagaria C,Andriulli A,Devoto M,Annese V

更新日期：2006-02-15 00:00:00

abstract：:The present study examined whether histamine could affect the growth of the enterochromaffin-like (ECL) cell and the parietal cell. The effects of the unsurmountable histamine H2-receptor antagonist loxtidine (80 mg/kg) and the H+, K(+)-ATPase inhibitor omeprazole (100 mumol/kg) were compared in female Sprague-Dawley ...

journal_title：Alimentary pharmacology & therapeutics

authors： Brenna E,Waldum HL,Sandvik AK,Schulze Søgnen B,Kristensen A

更新日期：1992-06-01 00:00:00

abstract：:This review summarizes the clinical evidence to support current therapies in irritable bowel syndrome (IBS). Fibre is indicated at a dose of at least 12 g per day in patients with constipation-predominant IBS. Loperamide (and probably other opioid agonists) are of proven benefit in diarrhoea-predominant IBS; loperamid...

journal_title：Alimentary pharmacology & therapeutics

authors： Camilleri M

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:The use of proton pump inhibitors (PPIs) is extensive. While the incidence of new treatments remains stable, the prevalence of long-term treatment is rising. Studies have shown that up to 70% of patients on chronic acid suppression lack a verified indication for treatment. AIMS:To investigate primary care p...

journal_title：Alimentary pharmacology & therapeutics

authors： Reimer C,Bytzer P

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The use of healthcare resources for the management of constipation is not well-known. AIM:To analyse healthcare seeking for constipation, defined by three different criteria, and its related factors and to assess the frequency of use of laxatives, suppositories and enemas for the treatment of constipation. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Gálvez C,Garrigues V,Ortiz V,Ponce M,Nos P,Ponce J

更新日期：2006-07-15 00:00:00

abstract：AIM:To investigate the efficacy of two omeprazole triple therapies for the eradication of Helicobacter pylori, ulcer healing and ulcer relapse during a 6-month treatment-free period in patients with active duodenal ulcer. METHODS:This was a double-blind, randomized study in 15 centres across Canada. Patients (n = 149)...

journal_title：Alimentary pharmacology & therapeutics

authors： Zanten SJ,Bradette M,Farley A,Leddin D,Lind T,Unge P,Bayerdörffer E,Spiller RC,O'Morain C,Sipponen P,Wrangstadh M,Zeijlon L,Sinclair P

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:The various components of pain and quality of life in duodenal ulcer patients receiving antisecretory drugs have not been studied to date. METHODS:Ninety-five patients with epigastric pain and duodenal ulcer at endoscopy completed this prospective, multicenter, open-study. All were treated with effervescent...

journal_title：Alimentary pharmacology & therapeutics

authors： Rampal P,Ruszniewski P,Boureau F,Richard A,Slama A

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Data on whether long-acting somatostatin analogue octreotide causes or prevents pancreatic injury following endoscopic retrograde cholangiopancreatography (ERCP) are controversial. AIM:This multicentre, prospective trial studied the effect of octreotide on pancreatic injury in a large unselected group of pa...

journal_title：Alimentary pharmacology & therapeutics

authors： Tulassay Z,Döbrönte Z,Prónai L,Zágoni T,Juhász L

更新日期：1998-11-01 00:00:00

abstract：:The effects of treatment with the Chinese herbal medicine Liu-Jun-Zi-Tang (TJ-43) on gastric emptying and gastrointestinal symptoms were investigated in 42 patients with chronic idiopathic dyspepsia. By random allocation, 22 patients received oral treatment with 2.5 g TJ-43 three times daily, and 20 patients received ...

journal_title：Alimentary pharmacology & therapeutics

authors： Tatsuta M,Iishi H

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Cross-sectional imaging techniques, including ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI), are increasingly used for evaluation of Crohn's disease (CD). Aim  To perform an assessment of the diagnostic accuracy of cross-sectional imaging techniques for diagnosis of CD, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Panés J,Bouzas R,Chaparro M,García-Sánchez V,Gisbert JP,Martínez de Guereñu B,Mendoza JL,Paredes JM,Quiroga S,Ripollés T,Rimola J

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Infection with the hepatitis C virus (HCV) has been considered a major cause of mortality, morbidity and resource utilisation in the US. In addition, HCV is the main cause of hepatocellular cancer (HCC) in the US. Recent developments in the diagnosis and treatment of HCV, including new recommendations pertai...

journal_title：Alimentary pharmacology & therapeutics

authors： Younossi ZM,Kanwal F,Saab S,Brown KA,El-Serag HB,Kim WR,Ahmed A,Kugelmas M,Gordon SC

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Efficacy and safety of antiviral combination therapy in patients with Crohn's disease (CD) and chronic hepatitis C (CHC) is presently not established and consequently CHC is rarely treated in CD patients. AIM:To analyse the efficacy and tolerability of antiviral interferon/ribavirin therapy in patients with...

journal_title：Alimentary pharmacology & therapeutics

authors： Scherzer TM,Staufer K,Novacek G,Steindl-Munda P,Schumacher S,Hofer H,Ferenci P,Vogelsang H

更新日期：2008-09-15 00:00:00

abstract：BACKGROUND:Symptoms of irritable bowel syndrome are often cyclical and thus may require repeated rather than continuous therapy. Tegaserod is effective and well-tolerated for irritable bowel syndrome with constipation but data on retreatment are lacking. AIM:To assess whether tegaserod retreatment is as efficacious an...

journal_title：Alimentary pharmacology & therapeutics

authors： Müller-Lissner S,Holtmann G,Rueegg P,Weidinger G,Löffler H

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Although a few adult cases of fulminant-type autoimmune hepatitis have been reported, their clinical features and prognosis have remained uncertain. AIM:To assess the clinical features and prognosis of patients with fulminant-type autoimmune hepatitis. METHODS:Eleven patients (10%) diagnosed with fulminant...

journal_title：Alimentary pharmacology & therapeutics

authors： Miyake Y,Iwasaki Y,Terada R,Onishi T,Okamoto R,Sakai N,Sakaguchi K,Shiratori Y

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Some of mucosal defensive agents have anti-Helicobacter pylori activities. However, their effectiveness in eradicating H. pylori infection has not been evaluated. AIM:To assess the additive effect of mucosal defensive agents in eradication regimens using statistical analysis. METHODS:Pertinent studies were...

journal_title：Alimentary pharmacology & therapeutics

authors： Hojo M,Miwa H,Kikuchi S,Sato N

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Although incrimination of the intestinal microbiota in the pathogenesis of IBD is widely accepted, few data are available about the role of specific bacteria. Potentially, Faecalibacterium prausnitzii, bacteria with anti-inflammatory properties, might be deficient in ulcerative colitis (UC). AIM:To quantify...

journal_title：Alimentary pharmacology & therapeutics

authors： Varela E,Manichanh C,Gallart M,Torrejón A,Borruel N,Casellas F,Guarner F,Antolin M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The outbreak of coronavirus disease 2019 (COVID-19) is a critical challenge for public health. The effect of COVID-19 on liver injury has not been fully established. AIMS:To evaluate the dynamic changes in liver function and the relationship between liver damage and prognosis in patients with COVID-19. MET...

journal_title：Alimentary pharmacology & therapeutics

authors： Huang H,Chen S,Li H,Zhou XL,Dai Y,Wu J,Zhang J,Shao L,Yan R,Wang M,Wang J,Tu Y,Ge M

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Following a nil per os (NPO) regimen, most patients with acute pancreatitis (AP) can resume normal oral intake within 1 week. If not tolerated, it is recommended to initiate artificial feeding, preferably by the enteral route. AIM:To evaluate the nutritional management of patients with AP in a Dutch cohort ...

journal_title：Alimentary pharmacology & therapeutics

authors： Spanier BW,Mathus-Vliegen EM,Tuynman HA,Van der Hulst RW,Dijkgraaf MG,Bruno MJ,EARL Study Group.

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Drug toxicity is the leading cause of acute liver failure in the United States. Further understanding of hepatotoxicity is becoming increasingly important as more drugs come to market. AIMS:(i) To provide an update on recent advances in our understanding of hepatotoxicity of select commonly used drug classe...

journal_title：Alimentary pharmacology & therapeutics

authors： Chang CY,Schiano TD

更新日期：2007-05-15 00:00:00

abstract：BACKGROUND:In behavioural economics, a 'nudge' describes configuration of a choice to encourage a certain action without taking away freedom of choice. AIM:To determine the impact of a 'nudge' strategy - prefilling either 3mL or 5mL syringes with midazolam - on endoscopic sedation practice. METHODS:Consecutive patien...

journal_title：Alimentary pharmacology & therapeutics

authors： Harewood GC,Clancy K,Engela J,Abdulrahim M,Lohan K,O'Reilly C

更新日期：2011-07-01 00:00:00