Distinct roles for sarcolemmal and mitochondrial adenosine triphosphate-sensitive potassium channels in isoflurane-induced protection against oxidative stress.

abstract：BACKGROUND:Sympathetic nerve activity was recorded in the leg during high thoracic epidural anesthesia with a segmental sensory blockade of the upper thoracic dermatomes to test the hypothesis that the sympathetic blockade accompanying thoracic epidural anesthesia includes caudal parts of the sympathetic nervous system...

journal_title：Anesthesiology

authors： Magnúsdóttir H,Kirnö K,Ricksten SE,Elam M

更新日期：1999-11-01 00:00:00

abstract：:The effect on measured potassium values of a number of factors involved in sample acquisition and preparation were investigated. Measured potassium values in either plasma or serum were not influenced by the site of sample withdrawal, the presence of a tourniquet, or the time elapsed between blood sampling and analysi...

journal_title：Anesthesiology

authors： Hill AB,Nahrwold ML,Noonan D,Northrop P

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:Perioperative ischemic optic neuropathy (ION) causes visual loss in spinal fusion. Previous case-control studies are limited by study size and lack of a random sample. The purpose of this study was to study trends in ION incidence in spinal fusion and risk factors in a large nationwide administrative hospita...

journal_title：Anesthesiology

authors： Rubin DS,Parakati I,Lee LA,Moss HE,Joslin CE,Roth S

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Propofol and isoflurane anesthesia were studied previously with functional brain imaging in humans to begin identifying key brain areas involved with mediating anesthetic-induced unconsciousness. The authors describe an additional positron emission tomography study of halothane's in vivo cerebral metabolic e...

journal_title：Anesthesiology

authors： Alkire MT,Pomfrett CJ,Haier RJ,Gianzero MV,Chan CM,Jacobsen BP,Fallon JH

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) formed from L-arginine is exhaled by mammals and regulates pulmonary vascular tone. Little is known about how its formation is stimulated. METHODS:The concentration of NO in exhaled air was monitored by chemiluminescence in pentobarbital-anesthetized rabbits receiving mechanical ventilatio...

journal_title：Anesthesiology

authors： Persson MG,Lönnqvist PA,Gustafsson LE

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:During muscular exercise, a negative correlation has been demonstrated between the value of mixed venous oxygen saturation (SvO2) and the level of muscular work, expressed at each level as the ratio of oxygen uptake (VO2) to each subject's maximal oxygen uptake (VO2max). Because the immediate postoperative p...

journal_title：Anesthesiology

authors： Viale JP,Annat G,Lehot JJ,Quard S,Quintin L,Parlow J,Durand PG,Zabot JM,Villard J,Estanove S

更新日期：1994-02-01 00:00:00

abstract：:The authors used pharmacokinetic and pharmacodynamic modeling to explain the time course of neuromuscular blockade following single or multiple doses of three nondepolarizing muscle relaxants. Published and unpublished pharmacokinetic and pharmacodynamic data for 13 normal subjects were used to simulate the duration o...

journal_title：Anesthesiology

authors： Fisher DM,Rosen JI

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Awareness during anesthesia is foremost assessed with postoperative interviews, which may underestimate its incidence. On-line monitors such as the Bispectral Index and patient response to verbal command are not necessarily commonly used. This study investigated response to command during deep sedation (Bisp...

journal_title：Anesthesiology

authors： Kerssens C,Klein J,Bonke B

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:To assess the performance of transcranial Doppler (TCD) in predicting neurologic worsening after mild to moderate traumatic brain injury. METHODS:The authors conducted a prospective observational study across 17 sites. TCD was performed upon admission in 356 patients (Glasgow Coma Score [GCS], 9 to 15) with...

journal_title：Anesthesiology

authors： Bouzat P,Almeras L,Manhes P,Sanders L,Levrat A,David JS,Cinotti R,Chabanne R,Gloaguen A,Bobbia X,Thoret S,Oujamaa L,Bosson JL,Payen JF,Asehnoune K,Pes P,Lefrant JY,Mirek S,Albasini F,Scrimgeour C,Thouret JM,Char

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Amyloid deposition is a potential contributor to postoperative cognitive dysfunction. The authors hypothesized that 6-week global cortical amyloid burden, determined by F-florbetapir positron emission tomography, would be greater in those patients manifesting cognitive dysfunction at 6 weeks postoperatively....

journal_title：Anesthesiology

authors： Klinger RY,James OG,Borges-Neto S,Bisanar T,Li YJ,Qi W,Berger M,Terrando N,Newman MF,Doraiswamy PM,Mathew JP,Alzheimer’s Disease Neuroimaging Initiative (ADNI) Study Group.,Neurologic Outcomes Research Group (NORG).

更新日期：2018-04-01 00:00:00

abstract：INTRODUCTION:Opioids are powerful analgesics, but are also common drugs of abuse. Few studies have examined how neuropathic pain alters the pharmacology of opioids in modulating limbic pathways that underlie abuse liability. METHODS:Rats with or without spinal nerve ligation (SNL) were implanted with electrodes into t...

journal_title：Anesthesiology

authors： Ewan EE,Martin TJ

更新日期：2011-03-01 00:00:00

abstract：:Five healthy, nonpregnant volunteers were studied before and after induction of lumbar epidural anesthesia to determine the cause of central hypothermia during epidural anesthesia. Cutaneous heat loss was measured from 10 area-weighted sites using thermal flux transducers. Oxygen consumption was measured and converted...

journal_title：Anesthesiology

authors： Hynson JM,Sessler DI,Glosten B,McGuire J

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Factor VII is the most affected clotting factor during the early phase of warfarin therapy. An international normalized ratio (INR) of more than 1.4 is considered unsafe for epidural catheter placement or removal, according to the American Society of Regional Anesthesia and Pain Medicine. The authors tested ...

journal_title：Anesthesiology

authors： Benzon HT,Avram MJ,Benzon HA,Kirby-Nolan M,Nader A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The distribution and elimination of 0.9% saline given by intravenous infusion has not been compared between the conscious state and during inhalational anesthesia. METHODS:Six adult sheep received an intravenous infusion of 25 ml/kg of 0.9% saline over 20 min in the conscious state and also during isofluran...

journal_title：Anesthesiology

authors： Brauer KI,Svensén C,Hahn RG,Traber LD,Prough DS

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Due to potential neurologic sequelae, the risk:benefit ratio of thoracic epidural analgesia is controversial. Surprisingly, however, few available data address neurologic complications. The incidence of neurologic complications occurring after thoracic epidural catheterization was studied in patients schedul...

journal_title：Anesthesiology

authors： Giebler RM,Scherer RU,Peters J

更新日期：1997-01-01 00:00:00

abstract：:The serum and urinary concentrations of fluorinated metabolites of isoflurane after inhalation of three different concentrations of isoflurane were studied in 18 ASA physical status 1 or 2 patients, scheduled for orthopedic or otolaryngeal surgery. Isoflurane was administered for 60 min during fentanyl-nitrous oxide-o...

journal_title：Anesthesiology

authors： Davidkova T,Kikuchi H,Fujii K,Mukaida K,Sato N,Kawachi S,Morio M

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Intraspinally administered alpha 2-adrenergic agonists may relieve pain in sympathetically maintained pain (SMP) syndromes, such as reflex sympathetically dystrophy (RSD), by spinal, peripheral, and central nervous system actions. This study examined analgesic efficacy and side effects of epidurally administ...

journal_title：Anesthesiology

authors： Rauck RL,Eisenach JC,Jackson K,Young LD,Southern J

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Single lung transplantation has become a viable therapy for treatment of end-stage pulmonary disease. We previously observed that left lung autotransplantation (LLA) results in a chronic increase in pulmonary vascular resistance and enhanced pulmonary vascular reactivity to sympathetic alpha adrenoreceptor a...

journal_title：Anesthesiology

authors： Lennon PF,Murray PA

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The authors compared the intubation success rate of straight reinforced tracheal tubes emerging from the Airtraq laryngoscope (Prodol Meditec S.A., Vizcaya, Spain) with standard preformed polyvinyl chloride tracheal tubes in anesthetized patients. METHODS:The authors randomly allocated 347 adult patients to...

journal_title：Anesthesiology

authors： Dimitriou VK,Zogogiannis ID,Douma AK,Pentilas ND,Liotiri DG,Wachtel MS,Karakitsos D

更新日期：2009-12-01 00:00:00

abstract：:Four volunteers judged eight levels of thermal stimuli induced by a Hardy dolorimeter, varying in intensity from extremely painful to a low level seldom even perceived. Half of the 406 stimuli were applied during acupuncture and half either before insertion or after removal of the needles. The experimental design mini...

journal_title：Anesthesiology

authors： Day RL,Kitahata LM,Kao FF,Motoyama EK,Hardy JD

更新日期：1975-11-01 00:00:00

abstract：:To study the effect of needle bevel direction on the incidence and severity of headache following inadvertent dural puncture occurring during the identification of the epidural space, the authors randomly assigned obstetric anesthesia residents to identify epidural space with the bevel of the epidural needle oriented ...

journal_title：Anesthesiology

authors： Norris MC,Leighton BL,DeSimone CA

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Opioids are used by patients who have conditions ranging from the acute pain of surgery and chronic cancer pain to substance abuse. Despite their widespread use and considerable experimental data about them, little is known about how opioids may alter in vivo immunity in humans. This study was designed to ev...

journal_title：Anesthesiology

authors： Yeager MP,Colacchio TA,Yu CT,Hildebrandt L,Howell AL,Weiss J,Guyre PM

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:There is an increasing interest in the use of dexmedetomidine for anesthesia and sedation. Here, we used the mouse organotypic hippocampal slice culture to investigate whether dexmedetomidine exhibits postconditioning properties against oxygen and glucose deprivation (OGD). The role of the focal adhesion and...

journal_title：Anesthesiology

authors： Dahmani S,Rouelle D,Gressens P,Mantz J

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The Pediatric Craniofacial Collaborative Group established the Pediatric Craniofacial Surgery Perioperative Registry to elucidate practices and outcomes in children with craniosynostosis undergoing complex cranial vault reconstruction and inform quality improvement efforts. The aim of this study is to determ...

journal_title：Anesthesiology

authors： Stricker PA,Goobie SM,Cladis FP,Haberkern CM,Meier PM,Reddy SK,Nguyen TT,Cai L,Polansky M,Szmuk P,Fiadjoe J,Soneru C,Falcon R,Petersen T,Kowalczyk-Derderian C,Dalesio N,Budac S,Groenewald N,Rubens D,Thompson D,Wat

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:The analgesic activity of morphine-6-glucuronide (M-6-G) is well recognized for its contribution to the effects of morphine and its possible use as an opioid analgesic with a wider therapeutic range than morphine. The present study attempted to quantify the relative contribution of M-6-G to analgesia observe...

journal_title：Anesthesiology

authors： Lötsch J,Kobal G,Stockmann A,Brune K,Geisslinger G

更新日期：1997-12-01 00:00:00

abstract：:Pain perception to minor physical stimuli has been hypothesized to be related to subsequent pain ratings after surgery. The objective of this systematic review was to evaluate the correlation between preoperative pain sensitivity and postoperative pain intensity. After a literature search of MEDLINE, EMBASE, and meeti...

journal_title：Anesthesiology

authors： Abrishami A,Chan J,Chung F,Wong J

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:An initial pilot study of 300 sub-Tenon local anesthetic blocks (STBs) for intraocular surgery established the effectiveness and patient acceptability of the technique. Following this, a decision was made in 1995 to change from sharp needle techniques to STB for all eye surgeries performed during local anest...

journal_title：Anesthesiology

authors： Guise PA

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Drugs used for sedation in anesthesia and intensive care may cause pharyngeal dysfunction and increased risk for aspiration. In this study, the authors investigate the impact of sedative doses of morphine and midazolam on pharyngeal function during swallowing and coordination of breathing and swallowing. ME...

journal_title：Anesthesiology

authors： Hårdemark Cedborg AI,Sundman E,Bodén K,Hedström HW,Kuylenstierna R,Ekberg O,Eriksson LI

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The linearity of cisatracurium elimination and its concentration-effect relation were determined as part of a traditional rich data study with three dose levels in patients receiving balanced anesthesia. METHODS:Forty-eight adults with American Society of Anesthesiologists status I-II were randomized to rec...

journal_title：Anesthesiology

authors： Bergeron L,Bevan DR,Berrill A,Kahwaji R,Varin F

更新日期：2001-08-01 00:00:00

abstract：:Previous investigators have identified an aortic-to-radial artery pressure gradient thought to develop during rewarming and discontinuation of cardiopulmonary bypass. The authors measured mean aortic and radial artery pressures before, during, and after cardiopulmonary bypass in 30 patients, to determine when the pres...

journal_title：Anesthesiology

authors： Rich GF,Lubanski RE Jr,McLoughlin TM

更新日期：1992-07-01 00:00:00