Abstract：
:Thrombangiitis obliterans (TAO), or Buerger's disease, is most likely an endarteritis that is introduced by T-cell-mediated cellular immunity and B-cell-mediated humoral immunity associated with the activation of macrophages or dendritic cells in the intima. There is no specific marker of the disease, and the diagnosis is based on clinical and angiographic criteria. The disease spontaneously leads to tissue loss and major amputations and is self-limiting in the 5th to 6th decades of life. Patients should quit smoking and be offered treatment with prostaglandin or prostacyclin, modern wound management, and pain-relieving drugs. Surgical revascularization may be indicated in elective patients, and amputation should only be the last option. It has been suggested that environmental factors may play a major role in the modification of the disease process. TAO is a typical lower class disease, the social and psychological components of which are widely unexplored. Unfortunately, the last decade has not taught us anything to enable us to improve the treatment of TAO patients.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Kröger Kdoi
10.1016/j.ejim.2005.11.020subject
Has Abstractpub_date
2006-07-01 00:00:00pages
227-34issue
4eissn
0953-6205issn
1879-0828pii
S0953-6205(06)00042-2journal_volume
17pub_type
杂志文章abstract：:BACKGROUND: Antineutrophil cytoplasmic antibodies (ANCA) can be associated with various disorders. However, their association with neutropenia has never been reported. METHODS: Nine patients with chronic unexplained neutropenia and ANCA were studied. Clinical charts were extensively analyzed and all patients underwent...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2004.08.009
更新日期：2004-11-01 00:00:00
abstract：:Oncogenic osteomalacia (OOM) is a rare but curable cause of metabolic bone disease. We report 9 patients with OOM, including 2 patients with occult nasal sinus tumours and 1 in whom a progressive increase in the post-operative FGF23 level heralded the development of metastatic pulmonary disease. The median duration of...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2008.01.011
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:Left ventricular (LV) dysfunction is a predictor of mortality in patients with sepsis. However, whether the adverse impact of LV dysfunction depends on fluid balance remains unclear. We retrospectively investigated the impact of LV dysfunction and fluid balance on various outcomes of patients with sepsis. ME...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2019.11.019
更新日期：2020-04-01 00:00:00
abstract：:Portopulmonary hypertension is a form of pulmonary arterial hypertension that has gained interest in recent years with the development of liver transplantation techniques and new pulmonary vasodilator therapies. Portopulmonary hypertension is defined as pulmonary artery hypertension associated with portal hypertension...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2011.02.018
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Heart failure (HF) with reduced ejection fraction remains a major therapeutic challenge. The aim of this study was to investigate the role of novel cardiovascular biomarkers, i.e. soluble suppression of tumorigenicity (sST2), growth-differentiation factor-15 (GDF-15), soluble urokinase plasminogen activator ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2017.05.027
更新日期：2017-10-01 00:00:00
abstract：:Enteric fever (EF) is the most common bacteremic disease affecting travelers to the tropics. For more than a decade, fluoroquinolones have been considered the drugs of choice for EF. However, recent reports have raised concern about fluoroquinolone resistance. Treatment with ciprofloxacin failed in a traveler with Sal...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.09.016
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:The benefit of reducing the risk of stroke against increasing the risk of renal progression associated with antiplatelet therapy in patients with advanced chronic kidney disease (CKD) is controversial. METHODS:We enrolled 1301 adult patients with advanced CKD treated with erythropoiesis stimulating agents f...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2016.11.009
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Prognostic factors of mortality in elderly patients with dementia with aspiration pneumonia (AP) are scarcely known. We determined the mortality rate and prognostic factors in old patients with dementia hospitalized due to AP. METHODS:We prospectively studied 120 consecutive patients aged ≥ 75 years with de...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2012.08.006
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Patients admitted to general internal medicine wards might receive a large number of drugs and be at risk for drug-related problems (DRPs) associated with increased morbidity and mortality. This study aimed to detect suboptimal drug use in internal medicine by a pharmacotherapy evaluation, to suggest treatme...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.05.012
更新日期：2015-07-01 00:00:00
abstract：:We report two patients with isolated bone marrow non-Hodgkin's lymphoma and we review the additional 23 cases thus far described. Bicytopenia or pancytopenia and an elevated erythrocyte sedimentation rate were universally present. Some 84% of the patients manifested fever of unknown origin (FUO), 64% constitutional sy...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(02)00216-9
更新日期：2003-03-01 00:00:00
abstract：AIM:Intravenous insulin improves clinical outcome in patients hospitalized in intensive care units. Whether glucose control with multiple daily subcutaneous insulin injections (MDI) is beneficial in patients hospitalized in general medical wards is unknown. We tested the feasibility, safety and efficacy of glucose cont...
journal_title：European journal of internal medicine
pub_type： 临床试验,杂志文章
doi：10.1016/j.ejim.2008.12.010
更新日期：2009-07-01 00:00:00
abstract：:Background: Cases of lipodystrophy syndrome and metabolic disorders have been described since the onset of highly active antiretroviral therapy in HIV-infected patients. The aim of our study was to estimate the prevalence of lipodystrophy (LD) and to define the associated lipid profile of these patients. Methods: The ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(00)00103-5
更新日期：2000-10-01 00:00:00
abstract：:Pattern recognition of the long-term disease course before, during, and after pregnancy can provide us with data about the influence of pregnancy on IBD, and vice versa. Determinants that predict an indolent versus an aggressive disease course are currently being sought. Our intention is to analyze the disease course ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(00)00088-1
更新日期：2000-08-01 00:00:00
abstract：BACKGROUND:Anemia may have important deleterious effects on patients with heart failure. We investigated the presence and causes of anemia among patients admitted because of new-onset congestive heart failure. The prognostic value of anemia was also evaluated. METHODS:We evaluated the presence of anemia, which was def...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2005.11.015
更新日期：2006-05-01 00:00:00
abstract：:In recent years, new concepts of educational theory and practice have stimulated new approaches to medical education in many countries. For various reasons, medical education in Ireland has been slow to change such that there are now increasing concerns about educational standards. In addition, Ireland currently produ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.09.001
更新日期：2007-03-01 00:00:00
abstract：:Background: Big cities were particularly affected by tuberculosis in the 1990s. Methods: We studied 141 cases of extrapulmonary tuberculosis in patients not infected by HIV in the northeastern suburbs of Paris. Results: A total of 84 men and 57 women were included in the study. Their average age at diagnosis was 42.2 ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(00)00076-5
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND:Low serum levels of alkaline phosphatase (ALP) are a hallmark of hypophosphatasia. However, the clinical significance and the underlying genetics of low ALP in unselected populations are unclear. METHODS:In order to clarify this issue, we performed a clinical, biochemical and genetic study of 42 individuals...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.12.019
更新日期：2016-04-01 00:00:00
abstract：:Anthracosis is a form of pneumoconiosis caused by coal dust or by a smoky and polluted environment. Anthracosis often presents in pulmonary form; only rarely are extrathoracic, esophageal, and mediastinal anthracoses documented. We report a rare case of anthracosis with multiple mediastinal lymphadenopathy. ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2003.09.001
更新日期：2003-11-01 00:00:00
abstract：:Kingella kingae is an aerobic gram-negative coccobacillus that has been associated predominantly with bone and joint infection but also with septicemia and endocarditis. Until now, only four cases of proven K. kingae meningitis have been reported. We describe a case of a K. kingae meningitis in a male adolescent who p...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(00)00115-1
更新日期：2000-12-20 00:00:00
abstract：:Background: Thrombomodulin (TM) is a membrane glycoprotein in the vascular endothelium. It may be cleaved from endothelial cells and released into the circulation. The plasma TM level depends on the integrity of the endothelium and the clearance of the molecule. The physiological role of soluble TM forms is still uncl...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(00)00066-2
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:Diabetic patients with renal disease have increased mortality, largely from cardiovascular disease. This could be related to insulin resistance or to other inherited factors. The aim of the present study was to investigate whether there is evidence of the familial aggregation of increased mortality, even in ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2005.07.005
更新日期：2005-11-01 00:00:00
abstract：:Angiomyolipomas are very common in patients with tuberous sclerosis complex (TSC) and cause substantial morbidity. Until now, arterial embolization has been the recommended treatment for symptomatic patients. We report the case of a woman with TSC and giant angiolipomas in whom sirolimus induced a dramatic reduction i...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.07.017
更新日期：2007-01-01 00:00:00
abstract：:Most patients above 60 years with acute myeloid leukemia (AML) will die from their disease. Nevertheless, the treatment concepts in elderly patients with myelodysplastic syndromes (MDS) and AML are rapidly evolving. A number of recent reports have identified better survival rates with intensive induction chemotherapy ...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2018.05.026
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Penicillamine (PA) treatment may be associated with a wide spectrum of adverse effects. There are many case reports and small series of PA-induced nephrotic syndrome (NS). In addition to our patient, in this study, we review all the cases of NS due to PA treatment in the English literature. METHODS:A retros...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.03.001
更新日期：2006-08-01 00:00:00
abstract：:CHF is a disease of high incidence and prevalence in the elderly. Anemia is associated with an increased mortality in these patients. Erythropoietin secretion is reduced in these patients due to complexed mechanisms. Although some improvement in quality of life has been shown when using ESAs it has not been found any ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2013.12.011
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:The value of salivary cortisol measurement to study stress-related adrenal response is controversial. The study aim was to assess the role of salivary cortisol measurement to detect time-related changes of adrenal response in critically ill patients. PATIENTS AND METHODS:Patients with organ failure, sepsis ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2019.08.001
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:The activation of complement system is associated with the development of hepatitis B virus-associated membranous nephropathy (HBV-MN) and heparin could inhibit the activation of complement system. METHODS:This was a three-center trial. Seventy-nine patients with HBV-MN participated in the study. The follow...
journal_title：European journal of internal medicine
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ejim.2016.04.017
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Bleeding assessment tools (BATs) have been developed to quantify bleeding severity. Their ability to predict for the diagnosis of a bleeding disorder has not been thoroughly investigated. OBJECTIVES:To evaluate the ability of the Vicenza BAT and the ISTH BAT to distinguish patients with an established bleed...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2020.04.023
更新日期：2020-08-01 00:00:00
abstract：:BACKGROUND: The aim of this retrospective study was to determine the clinical, laboratory, and radiological features of all adult patients with varicella-zoster virus pneumonia (VZVP) treated in our departments during the last 5 years. Important therapeutic and evolutionary features are also reported. METHODS: Fourtee...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2004.04.016
更新日期：2004-10-01 00:00:00
abstract：OBJECTIVE OF THE STUDY:To report on the results of two projects on chronic hepatitis B in Western Balkans lead by Ioannina, Northwest Greece and Tirana, Albania. METHODS:In two prospective projects, HEPAGA I and HEPAGA II which lasted 4 years. In HEPAGA I, serum samples from 410 Albanians were tested for HBV. In HEPAG...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2009.07.016
更新日期：2009-11-01 00:00:00
