Granulocytes in the inflammatory process of BALB/c mice infected by Leishmania amazonensis. A quantitative approach.


:We used previously immunized (partially resistant) and naive (highly susceptible) BALB/c mice infected with Leishmania amazonensis for evaluating the role of granulocytes in the course of murine leishmaniasis. The animals were examined at different times post-infection and granulocytes counted in lesion tissues examined ultra-structurally. Polymorphonuclear granulocytes predominated during the early phase of infection and their number decreased with progression of infection; their number was similar in both groups during the early and intermediate phases of infection, though slightly higher in immunized animals during the late phase. Eosinophils represented approximately 10% of cells in the inflammatory infiltrate, being higher during the intermediate phase, and not differing between the groups. Another approach was the evaluation of granulocyte migration to the peritoneal cavity of susceptible BALB/c mice or resistant C57BL/6 mice under several stimuli. There was no statistically significant difference between resistant and susceptible animals in any of the treatments. Despite the influx of granulocytes to the lesion and its possible role in the initial destruction of injected Leishmania, this aspect does not seem to have an important effect on the outcome of the leishmanial infection.


Acta Trop


Acta tropica


Pompeu ML,Freitas LA,Santos ML,Khouri M,Barral-Netto M




Has Abstract


1991-01-01 00:00:00














  • Nectar protein content and attractiveness to Aedes aegypti and Culex pipiens in plants with nectar/insect associations.

    abstract::We chose five easily propagated garden plants previously shown to be attractive to mosquitoes, ants or other insects and tested them for attractiveness to Culex pipiens and Aedes aegypti. Long term imbibition was tested by survival on each plant species. Both mosquito species survived best on Impatiens walleriana, the...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Chen Z,Kearney CM

    更新日期:2015-06-01 00:00:00

  • Studies on the ecology of Bulinus globosus, the intermediate host of Schistosoma haematobium in the Ifakara area, Tanzania.

    abstract::During a period of 2 years, the ecology of Bulinus globosus was studied in 8 habitats in two streams near Ifakara, SE-Tanzania. The relative Bulinus densities were followed monthly. Two different methods for estimating snail densities (man/time vs. palmleaf traps) gave comparable results. Bulinus densities were consta...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Marti HP,Tanner M,Degrémont AA,Freyvogel TA

    更新日期:1985-06-01 00:00:00

  • Plant products used as mosquito repellents in Guinea Bissau, West Africa.

    abstract::By standardized interviews of people in 23 rural villages, in the Oio region of Guinea Bissau, we collected data on which plant species and plant derived products or methods people use to reduce mosquito biting activity. The following plants were used to reduce numbers of mosquitoes indoors at night: fresh or smoulder...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Pålsson K,Jaenson TG

    更新日期:1999-01-15 00:00:00

  • Magnetic affinity enzyme-linked immunoassay based on recombinant 26 kDa glutathione-S-transferase for serological diagnosis of schistosomiasis japonica.

    abstract::Schistosomiasis remains a serious worldwide public health problem. Improving the diagnostic assay for surveillance and monitoring will contribute to hastening the possible elimination of the disease in endemic regions. Therefore, this study aims to develop magnetic affinity enzyme-linked immunoassay (MEIA) for serolog...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Yu Q,Yang H,Feng Y,Yang X,Zhu Y

    更新日期:2012-12-01 00:00:00

  • Evaluation of the antidiarrhoeal effects of Zizyphus spina-christi stem bark in rats.

    abstract::The antidiarrhoeal effects of the methanol extract of Zizyphus spina-christi stem bark were evaluated in laboratory rodents. Studies on castor oil induced diarrhoea, intraluminal fluid accumulation, and gastrointestinal transit time were carried out. Results obtained revealed that the extract caused a dose dependent p...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Adzu B,Amos S,Amizan MB,Gamaniel K

    更新日期:2003-07-01 00:00:00

  • Blood-feeding performance of nymphs and adults of Triatoma brasiliensis on human hosts.

    abstract::The blood-feeding behaviour of nymphs and adults of Triatoma brasiliensis fed on the forearm of human volunteers was studied by electronic monitoring of the cibarial pump. Parameters of total contact time (TT), initial weight (IW), weight gain (WG), ingestion rate (IR), pump frequency (F), quantity of liquid ingested ...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Guarneri AA,Diotaiuti L,Gontijo NF,Gontijo AF,Pereira MH

    更新日期:2003-08-01 00:00:00

  • Detection of Leishmania (Viannia) braziliensis complex in wild mammals from Colombian coffee plantations by PCR and DNA hybridization.

    abstract::The small mammal fauna of coffee plantations in SW Colombia was surveyed to determine which of the species present were infected with parasites of the Leishmania (Viannia) braziliensis complex and might therefore act as reservoirs of human cutaneous leishmaniasis. Fifty animals of seven different species were captured...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Alexander B,Lozano C,Barker DC,McCann SH,Adler GH

    更新日期:1998-03-01 00:00:00

  • Transfusion transmitted Chagas disease: is it really under control?

    abstract::Transfusion transmitted Chagas disease was recognized as a medical problem more than 50 years ago. However, little attention was paid to it by Transfusion Medicine, medical authorities or regulatory agencies as a major problem and threat (especially after the advent of HIV/AIDS); perhaps because it was mainly restrict...

    journal_title:Acta tropica

    pub_type: 杂志文章,评审


    authors: Wendel S

    更新日期:2010-07-01 00:00:00

  • Schistosoma rodhaini: intramolluscan larval development, migration and replication processes of daughter sporocysts.

    abstract::The larval development of Schistosoma rodhaini in Biomphalaria glabrata presents two features of interest. The first concerns the migration of daughter sporocysts: only a fraction of the daughter sporocysts produced by the mother sporocyst migrate directly towards the digestive gland of the snail and become cercarioge...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Théron A,Touassem R

    更新日期:1989-01-01 00:00:00

  • A study of host preference in tsetse flies using a modified heteroduplex PCR-based method.

    abstract::A study of host preference in tsetse flies using a modified heteroduplex PCR-based method is described. Domestic and wild animal blood samples were collected to extract the corresponding reference DNAs. In Campo (south Cameroon), tsetse flies (mainly Glossina palpalis palpalis) were trapped and 41 bloodmeals were coll...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Njiokou F,Simo G,Mbida Mbida A,Truc P,Cuny G,Herder S

    更新日期:2004-07-01 00:00:00

  • Detection of Trypanosoma cruzi infection in naturally infected dogs and cats using serological, parasitological and molecular methods.

    abstract::Domestic dogs and cats are major domestic reservoir hosts of Trypanosoma cruzi and a risk factor for parasite transmission. In this study we assessed the relative performance of a polymerase chain reaction assay targeted to minicircle DNA (kDNA-PCR) in reference to conventional serological tests, a rapid dipstick test...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Enriquez GF,Cardinal MV,Orozco MM,Schijman AG,Gürtler RE

    更新日期:2013-06-01 00:00:00

  • Extraction of Schistosoma haematobium antigens from infected human urine and generation of potential diagnostic monoclonal antibodies to urinary antigens.

    abstract::Proteins in Schistosoma haematobium infected human urine were concentrated by precipitation with saturated ammonium sulphate 50% (v/v) and various fractions obtained at different stages of precipitation tested for presence of schistosome antigens (ShAgs) by dot-ELISA. The protein fraction (UP2S) obtained following two...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Bosompem KM,Arishima T,Yamashita T,Ayi I,Anyan WK,Kojima S

    更新日期:1996-10-01 00:00:00

  • Effects of carbon dioxide anaesthetic on Glossina.

    abstract::Exposure of 2 day old virgin females of Glossina fuscipes fuscipes, G. pallidipes, G. brevipalpis, and G. morsitans centralis to carbon dioxide anaesthesia for 15 sec has the effect of suppressing their subsequent insemination frequency. This insemination-inhibitory effect of the gas is more pronounced in G. f. fuscip...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Moloo SK,Kutuza SB

    更新日期:1975-01-01 00:00:00

  • Towards elimination of schistosomiasis after 5000 years of endemicity in Egypt.

    abstract::Schistosomiasis is a snail-transmitted infectious disease caused by a long lasting infection with a blood fluke of the genus Schistosoma. S. haematobium and S. mansoni are the species endemic in Egypt. The country has been plagued and seriously suffered from schistosomiasis over the past 5000 years. Great strides had ...

    journal_title:Acta tropica

    pub_type: 杂志文章,评审


    authors: Abou-El-Naga IF

    更新日期:2018-05-01 00:00:00

  • First report on the occurance of intestinal Entamoeba spp. In pigs In China.

    abstract::Three Entamoeba spp. including E. suis, zoonotic E. polecki, and E. histolytica, have been described in pigs to date. However, little is known about the molecular epidemiology of these neglected parasites in pigs globally. In this study we surveyed the occurrence and molecular epidemiology of porcine Entamoeba spp. in...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Li WC,Geng JZ,Chen C,Qian L,Zhang T,Liu JL,Luo JX,Gu YF

    更新日期:2018-09-01 00:00:00

  • Phylogeography of human lymphatic filarial parasite, Wuchereria bancrofti in India.

    abstract::Wuchereria bancrofti, a nematode parasite causing human lymphatic filariasis is widely distributed in India. The phylogeography of this parasite was studied by constructing RAPD profiles of parasite populations collected from 71 microfilaria carriers residing in different geoclimatic regions of India. The analysis sho...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Thangadurai R,Hoti SL,Kumar NP,Das PK

    更新日期:2006-07-01 00:00:00

  • High-resolution remote sensing-based spatial modeling for the prediction of potential risk areas of schistosomiasis in the Dongting Lake area, China.

    abstract::The geographical distribution of snail (i.e., the intermediate host of schistosomiasis) is consistent with that of endemic areas. The suitable snail habitus requires necessary environmental conditions for snail population. The high-resolution remote sensing provides an important tool for the spatio-temporal analysis o...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Xue JB,Xia S,Zhang LJ,Abe EM,Zhou J,Li YY,Hao YW,Wang Q,Xu J,Li SZ,Zhou XN

    更新日期:2019-10-01 00:00:00

  • Anthropogenic environmental change and the emergence of infectious diseases in wildlife.

    abstract::By using the criteria that define emerging infectious diseases (EIDs) of humans, we can identify a similar group of EIDs in wildlife. In the current review we highlight an important series of wildlife EIDs: amphibian chytridiomycosis; diseases of marine invertebrates and vertebrates and two recently-emerged viral zoon...

    journal_title:Acta tropica

    pub_type: 杂志文章,评审


    authors: Daszak P,Cunningham AA,Hyatt AD

    更新日期:2001-02-23 00:00:00

  • The mosquito problem and type and costs of personal protection measures used in rural and urban communities in Pondicherry region, South India.

    abstract::Personal protection measures have become an important tool against mosquito nuisance. The severity of mosquito nuisance and the type and costs of personal protection measures in the Pondicherry region in South India have been investigated, using a structured questionnaire. The number of respondents sampled was 300 in ...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Snehalatha KS,Ramaiah KD,Vijay Kumar KN,Das PK

    更新日期:2003-09-01 00:00:00

  • The electronic song "Scary Monsters and Nice Sprites" reduces host attack and mating success in the dengue vector Aedes aegypti.

    abstract::Sound and its reception are crucial for reproduction, survival, and population maintenance of many animals. In insects, low-frequency vibrations facilitate sexual interactions, whereas noise disrupts the perception of signals from conspecifics and hosts. Despite evidence that mosquitoes respond to sound frequencies be...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Dieng H,The CC,Satho T,Miake F,Wydiamala E,Kassim NFA,Hashim NA,Morales Vargas RE,Morales NP

    更新日期:2019-06-01 00:00:00

  • Detection of Plasmodium knowlesi using recombinase polymerase amplification (RPA) combined with SYBR Green I.

    abstract::In this study, recombinase polymerase amplification (RPA) combined with SYBR Green I was developed for the detection of Plasmodium knowlesi. Positive samples were indicated with a green color while negative samples were orange. To increase the efficiency of amplification, an interval mixing step of samples after 3 to ...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Lai MY,Lau YL

    更新日期:2020-05-15 00:00:00

  • Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.

    abstract::Access to low-cost, effective diagnosis for leptospirosis is urgently needed in developing countries. The EIE-IgM-Leptospirose, a kit produced for public health laboratories in Brazil, was shown to have a sensitivity of 76% (77 of 102 patients) and 100% (102 of 102 patients) during acute and convalescent-phase leptosp...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: McBride AJ,Pereira FA,da Silva ED,de Matos RB,da Silva ED,Ferreira AG,Reis MG,Ko AI

    更新日期:2007-06-01 00:00:00

  • Clinical presentation and treatment outcome of sleeping sickness in Sudanese pre-school children.

    abstract:BACKGROUND:Existing data on human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense among children are limited. Here, we described the demographic, clinical, diagnostic, treatment and outcome characteristics of HAT in pre-school children from Kajo-Keji County, South Sudan in comparison with older patien...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Eperon G,Schmid C,Loutan L,Chappuis F

    更新日期:2007-01-01 00:00:00

  • Developing health research capability in Tanzania: from a Swiss Tropical Institute Field Laboratory to the Ifakara Centre of the Tanzanian National Institute of Medical Research.

    abstract::The paper summarizes the evolution of a biomedical field research station in Tanzania, established by a European institute, into a national health research and resource centre. The Swiss Tropical Institute Field Laboratory was founded in Ifakara in the Kilombero District in southeastern Tanzania in 1957. It has evolve...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Tanner M,Kitua A,Degrémont AA

    更新日期:1994-08-01 00:00:00

  • Immunogenicity of homogenates of the developmental stages of Litomosoides carinii in albino rats.

    abstract::Homogenates of different developmental stages of the filarial parasites, L. carinii, emulsified in Freund's complete adjuvant have been examined for their efficacy in conferring immunity to the infection in the albino rats. The results revealed that sonicated preparations of microfilariae and infective larvae induce h...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Mehta K,Subrahmanyam D,Sindhu RK

    更新日期:1981-09-01 00:00:00

  • Field evaluation of a semi-automatic funnel trap targeted the medically important non-biting flies.

    abstract::Bait-trapping is a useful approach for monitoring fly population dynamics, and it is an effective tool for physical control of pest species. The aim of this study was to test a newly developed semi-automatic funnel fly trap with some modifications of the former prototype fly trap to study medically important fly popul...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Klong-Klaew T,Sontigun N,Sanit S,Samerjai C,Sukontason K,Kurahashi H,Koehler PG,Pereira RM,Limsopatham K,Suwannayod S,Thanapornpoonpong SN,Chareonviriyaphap T,Sukontason KL

    更新日期:2017-12-01 00:00:00

  • Sequence analysis in partial genes of five isolates of Angiostrongylus cantonensis from Taiwan and biological comparison in infectivity and pathogenicity between two strains.

    abstract::Angiostrongylus cantonensis is the most common infectious agent causing eosinophilic meningitis and is present in Taiwan, Thailand and the Pacific islands. Clinical symptoms vary within different endemic regions, and their severity is probably dependent on the number of ingested parasites and the diversity among strai...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Lee JD,Chung LY,Wang LC,Lin RJ,Wang JJ,Tu HP,Wu ZD,Yen CM

    更新日期:2014-05-01 00:00:00

  • Spatial analysis of scrub typhus infection and its association with environmental and socioeconomic factors in Taiwan.

    abstract::We analyzed the spatial distribution of human cases of scrub typhus on the main island of Taiwan from 2003 to 2008 and implemented an island-wide survey of scrub typhus vectors (trombiculid chiggers) in 2007 and 2008. The standardized incidence rate 'SIR' incorporating inter-district variations in population, gender a...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Kuo CC,Huang JL,Ko CY,Lee PF,Wang HC

    更新日期:2011-10-01 00:00:00

  • Albendazole in treatment of human cystic echinococcosis: 12 years of experience.

    abstract::This review paper examines the evidence from published and previously unpublished sources for the efficacy and safety of albendazole (ABZ) obtained in the last 12 years. Benzimidazole treatment alone is not ideal, requiring prolonged administration over many weeks, with an unpredictable outcome in terms of response ra...

    journal_title:Acta tropica

    pub_type: 杂志文章,评审


    authors: Horton RJ

    更新日期:1997-04-01 00:00:00

  • A procedure for isolating and freezing metacyclic Trypanosoma brucei gambiense forms in the field.

    abstract::An adaptation of a modified procedure using anion-exchange centrifugation was evaluated to isolate and freeze in field conditions a high number of bloodstream forms of Trypanosoma brucei gambiense for direct in vitro culture. Pellets of trypanosomes were obtained from 62 patients in Central Africa. The presence of try...

    journal_title:Acta tropica

    pub_type: 杂志文章


    authors: Truc P,Likeufack CL,Mbongo N,Ebo'o Enyenga V

    更新日期:2004-04-01 00:00:00