Abstract:
:Interferon is an immunomodulating cytokine used to treat patients with different diseases, such as hepatitis C chronic infection. Pegylated interferon is a new type of interferon, developed to increase the half-life of the drug. Many side effects have been related to its use, including ocular toxicity and retinopathy. The most reported ocular findings are cotton-wool spots and hemorrhages located at the posterior pole and surrounding optic nerve head. We describe one case of pegylated interferon-associated retinopathy with visual loss. The patient had visual acuity improvement four weeks after discontinuation of the medication and the ocular findings became much more subtle.
journal_name
Arq Bras Oftalmoljournal_title
Arquivos brasileiros de oftalmologiaauthors
Avila MP,Freitas AM,Isaac DL,Bastos AL,Pena RVdoi
10.1590/s0004-27492006000200022subject
Has Abstractpub_date
2006-03-01 00:00:00pages
255-9issue
2eissn
0004-2749issn
1678-2925pii
S0004-27492006000200022journal_volume
69pub_type
杂志文章abstract:PURPOSE:To report the outcomes of bupivacaine injection for the treatment of comitant horizontal strabismus and evaluate clinical effectiveness and associated radiological changes. METHODS:This prospective observational clinical study was conducted on 10 patients with comitant horizontal strabismus of up to 40 prism d...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20200032
更新日期:2020-06-01 00:00:00
abstract::The main purpose of this report is to describe a case of ectopia lentis et pupillae syndrome, highlighting the secondary ocular complications and their differential diagnoses. A 27-year-old man presented with complaint of low visual acuity. No evidence of the syndrome was found at presentation. The results of suppleme...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492005000600024
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To evaluate the effectiveness of mitomycin C (MMC) in preventing recurrence of pterygium following conjunctival autograft transplantation (CAT). Ki-67 antigen to evaluate epithelial cell proliferation and fibroblast nuclear kariometry were used to assist treatment evaluation. METHODS:Twenty-nine patients with ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,随机对照试验
doi:10.1590/s0004-27492008000400019
更新日期:2008-07-01 00:00:00
abstract::A 43-year-old male with a history of eosinophilic angiocentric fibrosis presented with headache and double vision since 48 h. Idiopathic hypertrophic pachymeningitis was diagnosed based on nuclear magnetic resonance and comprehensive systemic study findings. Eosinophilic angiocentric fibrosis and idiopathic hypertroph...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 信件
doi:10.5935/0004-2749.20180050
更新日期:2018-06-01 00:00:00
abstract::Permanent visual loss can be caused by improper use of immunosuppressive therapy in cases of uveitis without differential diagnosis of syphilitic uveitis. We present four cases of syphilitic uveitis that were incorrectly diagnosed as being secondary to rheumatic diseases and were subsequently treated with immunosuppre...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20150047
更新日期:2015-05-01 00:00:00
abstract:PURPOSES:To investigate the intra-laboratory reproducibility of clinical features and to evaluate corneal optical anisotropies in a rabbit model of limbal stem cell deficiency. METHODS:Limbal injury was induced in the right eye of 23 adult New Zealand White rabbits using a highly aggressive protocol that combined 360 ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20180076
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:To report the impression cytology features of conjunctival nevi reported as more noticeable. METHODS:35 patients who reported that a conjunctival lesion had become more noticeable after color or size change were enrolled. On slit-lamp examination, a clinical diagnosis of nevus was made and lesions underwent im...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492009000200014
更新日期:2009-03-01 00:00:00
abstract::Trichoepithelioma is a benign skin tumor and is most commonly found on the face, however, there are few reports about its occurrence on the eyelids. It is not usually recognized because of its rarity, origin, biological potential, and controversial classification. The purpose of this paper is to report two cases of so...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492005000100026
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To investigate the reliability of ultrasound in determining the size and identify the sonographic features and artifacts generated by intraocular foreign bodies of different materials. METHODS:Experimental study using 36 enucleated porcine eyes. Fragments of nine different compositions (wood, glass, plastic, c...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492013000100005
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:To determine the incidence of positive corneoscleral rim cultures preserved in Optisol GS medium, to identify pathogens involved and possible recipient eye infection. METHODS:A hundred sixty-three corneoscleral rim cultures penetrating keratoplasties performed from January 2001 to January 2003 in the Hospital ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000100003
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To analyze the benefits after cataract surgery in professional activities. METHODS:A prospective, randomized study was conducted at the Clinical Hospital of the University of São Paulo. The patients had cataract surgery by phacoemulsification (PHACO) and by extracapsular extraction (EECP). RESULTS:The sample ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,随机对照试验
doi:10.1590/s0004-27492010000600003
更新日期:2010-11-01 00:00:00
abstract::Fungal endophthalmitis is a rare condition often associated with poor prognosis. We present a case of postoperative acute fungal endophthalmitis caused by the yeast-like fungus Stephanoascus ciferrii (Candida ciferrii). The fungus was resistant to fluconazole, voriconazole, and amphotericin B but susceptible to caspof...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20170048
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:To describe an outbreak of Pseudomonas aeruginosa endophthalmitis post cataract surgery. Clinical findings, treatment and outcome are discussed. METHODS:Clinical charts review of forty-five patients treated for endophthalmitis in a two-day period. The patients underwent primary vitrectomy, anterior chamber irr...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492012000500010
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To evaluate the fitting and use of a soft contact lens in keratoconic patients. METHODS:Retrospective study on 80 eyes of 66 patients, fitted with a special soft contact lens for keratoconus, at the Contact Lens Section of UNIFESP and private clinics. Keratoconus was classified according to degrees of disease ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492006000400018
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:To analyze the clinical outcomes of the ocular surface in patients with vitamin D deficiency after oral replacement. METHODS:A total of 40 patients with vitamin D deficiency were enrolled in the study. The patients received 50,000 units of oral vitamin D weekly over a period of 8 weeks. After 8 weeks, 1,500-2,...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20200043
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:To evaluated the retinal nerve fiber layer in chloroquine patients with optical coherence tomography (OCT). METHODS:Nerve fibers layer thickness was measured by a proprietary OCT Stratus through the fast retinal nerve fiber layer protocol in ninety-four eyes of 48 patients exposed to chloroquine for at least o...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492010000100005
更新日期:2010-01-01 00:00:00
abstract::Nature has always provided an unlimited source of biologically-active compounds. Since the beginning of mankind, humans have sought resources in fauna and flora to treat eye diseases. However, it was only after the Industrial Revolution that extracts of plants and substances of animal origin could be used safely, as h...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,评审
doi:10.5935/0004-2749.20180086
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:To report the impression cytologic results after corneal cross-linking and insertion of intrastromal corneal ring segments for keratoconus. METHODS:Thirty-nine eyes were distributed into two groups: 1) cross-linking group (patients underwent corneal cross-linking procedure), and 2) riboflavin eyedrops group (p...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,随机对照试验
doi:10.1590/s0004-27492012000200006
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To report a 16-year long-term follow-up of a patient with acute multifocal hemorrhagic retinal vasculitis (Blumenkranz syndrome). A 21-year old male was seen in 1994 with acute multifocal hemorrhagic retinal vasculitis (Blumenkranz syndrome), first in the left eye, and later in the right eye. He was treated wit...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492011000500013
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To assess the intraocular pressure (IOP) and ocular rigidity (E) at 1, 3, 6 and 24 postoperative months in eyes that underwent LASIK. METHODS:The IOP measured by Goldmann applanation tonometer (GAT) and by the 5.5 and 10 gm. weights of a standardized Schioetz tonometer (ST) and the E measured by differential t...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492009000400003
更新日期:2009-07-01 00:00:00
abstract:PURPOSES:To validate a teleophthalmology mobile system aimed at improving and providing eye urgency screenings in remote and poor area settings in Brazil. The system enables one or more ophthalmologists to remotely examine a patient's condition and submit a decision describing the gravity of the case. If necessary, the...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20140055
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To evaluate the biopsychosocial profile of patients with anophthalmia, with emphasis on the psychological and functional impact of eye loss and the social reintegration of this population. METHODS:Prospective analyses of 84 patients (50 males and 34 females), rehabilitated or in the rehabilitation process with...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000600017
更新日期:2008-11-01 00:00:00
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journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,多中心研究
doi:10.5935/0004-2749.20140089
更新日期:2014-11-01 00:00:00
abstract::Regardless of significant progress in the field of corneal transplantation to treat corneal opacification, some cases of corneal blindness still present a poor prognosis for conventional penetrating keratoplasty. In patients with repeated graft failure and/or with severe ocular surface disease, the Boston type I kerat...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,评审
doi:10.1590/s0004-27492012000300016
更新日期:2012-05-01 00:00:00
abstract::A 49-year-old woman with acute loss of vision in her left eye was examined in our clinic. Two months before arriving at out clinic, she was diagnosed with pancreatic endothelial carcinoma. Her visual acuities were 20/20 for the right and 20/200 for the left eye. Fundus examination and fundus fluorescein angiography sh...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20140065
更新日期:2014-08-01 00:00:00
abstract::The present study reports two cases of symptomatic essential trichomegaly. Trichomegaly may develop in various diseases, including anorexia nervosa, hypothyroidism, pregnancy, pretibial myxedema, systemic lupus erythematosus, vernal keratoconjunctivitis, and uveitis. The exact incidence trichomegaly is unknown, and th...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492013000100015
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:The outcomes of the treatment of retinopathy of prematurity (ROP) seem to be better in inborn patients than in those patients who were referred for ROP treatment. This study aims to investigate the timing of treatment and the outcomes in inborn patients and in patients referred for treatment to the Hospital de ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492011000400004
更新日期:2011-07-01 00:00:00
abstract::Report on the development of pseudohypopyon immediately after intravitreal injection of triamcinolone acetonide (TAAC). Two phakic patients presenting with a transient pseudohypopyon after having been treated with intravitreal triamcinolone. One had a clinically significant macular edema with cystoid component (CSME w...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492005000200018
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:To investigate whether the time interval between type 2 diabetes mellitus (DM) diagnosis and the first fundoscopic examination is related with the presence and the severity of diabetic retinopathy (DR) observed. METHODS:A survey of 105 type 2 DM patients referred to ophthalmologic evaluation in the "Hospital d...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492010000300006
更新日期:2010-05-01 00:00:00
abstract:Purpose::To evaluate whether reducing eyelid muscular force through the administration of botulinum toxin type A (BTX-A) to the orbicularis oculi muscles of patients with keratoconus affected corneal parameters indicative of disease progression. Methods::In this prospective parallel randomized clinical trial, 40 eyes ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,随机对照试验
doi:10.5935/0004-2749.20170022
更新日期:2017-03-01 00:00:00