The lethality of Euphorbia conspicua to adults of Biomphalaria glabrata, cercaria of Schistosoma mansoni and larvae of Artemia salina.

Abstract:

:Leaf extracts of Euphorbia conspicua (Euphorbiaceae), together with the latex and fractions derived therefrom, were evaluated for their molluscicidal and cercaricidal activities and their toxicities to brine shrimps. Whilst the leaf extracts were inactive against Biomphalaria glabrata, the latex, its triterpenic fraction and irritant fractions I and II exhibited high activities against adult snails with LC90 values of 4.87, 10.55, 0.64 and 0.10 microg/mL, respectively. The latex and its derived fractions were considered lethal to the cercaria of Schistosoma mansoni at concentrations of 100 microg/mL. The toxicities of the latex and the irritant fractions, but not of the triterpenic fraction, against Artemia salina were high with LC50 values < 10 microg/mL. The possible application of the latex of E. conspicua as an alternative natural molluscicide is considered.

journal_name

Bioresour Technol

journal_title

Bioresource technology

authors

dos Santos AF,de Azevedo DP,dos Santos Mata Rda C,de Mendonça DI,Sant'Ana AE

doi

10.1016/j.biortech.2005.11.020

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

135-9

issue

1

eissn

0960-8524

issn

1873-2976

pii

S0960-8524(05)00545-6

journal_volume

98

pub_type

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