Abstract:
OBJECTIVE:A polymorphism in the promoter region of the NPY gene at position -399 C > T was recently reported to be associated with schizophrenia in a Japanese population and with treatment refractory unipolar depression in a Swedish population. The objective of this study was to investigate potential associations between the polymorphism and three psychiatric disorders in a Danish population. METHOD:We investigated the occurrence of the polymorphism in patients with schizophrenia (n = 291), unipolar depression (n = 256) and panic disorder (n = 142) compared with controls (n = 716). RESULTS:We detected the polymorphism -399 C > T at a frequency of 48% in controls. No significant differences were found between genotype or allele frequencies in controls vs. the patient groups. CONCLUSION:The lack of association between the -399 C > T polymorphism and schizophrenia, unipolar depression or panic disorder, respectively, suggests that the polymorphism is not involved in the etiology of these disorders in the Danish population.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
Lindberg C,Koefoed P,Hansen ES,Bolwig TG,Rehfeld JF,Mellerup E,Jørgensen OS,Kessing LV,Werge T,Haugbøl S,Wang AG,Woldbye DPdoi
10.1111/j.1600-0447.2005.00648.xsubject
Has Abstractpub_date
2006-01-01 00:00:00pages
54-8issue
1eissn
0001-690Xissn
1600-0447pii
ACP648journal_volume
113pub_type
杂志文章abstract::A self-assessment scale has been developed and found to be a reliable instrument for detecting states of depression and anxiety in the setting of an hospital medical outpatient clinic. The anxiety and depressive subscales are also valid measures of severity of the emotional disorder. It is suggested that the introduct...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1983.tb09716.x
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abstract::Beck's Depression Inventory was administered in a study of all students aged 16-17 years in the first year of high school in a Swedish town, and was completed by 93% of them (n = 2270). Cronbach's reliability coefficient alpha was 0.89, and there were strong correlations between item scores and total scores. A diagnos...
journal_title:Acta psychiatrica Scandinavica
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doi:10.1111/j.1600-0447.1997.tb09632.x
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journal_title:Acta psychiatrica Scandinavica
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doi:10.1034/j.1600-0447.2003.00103.x
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb02739.x
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,随机对照试验
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb05073.x
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journal_title:Acta psychiatrica Scandinavica
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doi:10.1111/j.1600-0447.1988.tb05138.x
更新日期:1988-04-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.2008.01271.x
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb06234.x
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb02693.x
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abstract::Trends in death rates from all suicides and specific methods of suicide in Italy over the period 1955-79 were analysed on the basis of age-specific and age-standardised rates, and through a log-linear Poisson model to isolate the effects of age, birth cohort and calendar period. In both sexes, a large decrease in mort...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb10597.x
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pub_type: 杂志文章,评审
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1995.tb09735.x
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journal_title:Acta psychiatrica Scandinavica
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doi:10.1111/j.1600-0447.1989.tb10275.x
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journal_title:Acta psychiatrica Scandinavica
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更新日期:1984-01-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb05142.x
更新日期:1988-04-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1993.tb03461.x
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journal_title:Acta psychiatrica Scandinavica
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journal_title:Acta psychiatrica Scandinavica
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journal_title:Acta psychiatrica Scandinavica
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journal_title:Acta psychiatrica Scandinavica
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doi:10.1111/j.1600-0447.1987.tb02933.x
更新日期:1987-12-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-0447.1989.tb10298.x
更新日期:1989-06-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.1999.tb00984.x
更新日期:1999-06-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,meta分析,评审
doi:10.1111/acps.12556
更新日期:2016-05-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb06285.x
更新日期:1986-12-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12652
更新日期:2016-12-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/acps.12531
更新日期:2016-05-01 00:00:00
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journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0447.2001.00289.x
更新日期:2001-08-01 00:00:00
abstract::Patients receiving lithium who had noticed changes in hair texture since starting that drug, described variously as hair losing its curl or wave, have a greater lithium concentration in hair than patients on lithium with no such complaints. ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02626.x
更新日期:1985-10-01 00:00:00
abstract:OBJECTIVE:Ethnicity is a risk factor for tardive dyskinesia (TD) and other antipsychotic drug-induced movement disorders (ADIMD). It is unclear whether this association is mediated through genetic, environmental or cultural factors individually or in combination. This pilot study aimed to explore this interaction by de...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.2008.01183.x
更新日期:2008-06-01 00:00:00