Abstract:
:Ultraviolet B light (UVB) can have negative phototropic effects on fungi. Candida albicans is often found on human skin exposed to UVB. Therefore, it is of medical interest to know whether a negative phototropic response to UVB irradiation can support an invasive growth of this potentially dangerous agent. In our study we investigated how repeated irradiation with low doses of UVB can influence the hyphal growth of C. albicans. Six randomly chosen strains of C. albicans were tested. Formation of hyphae was induced and maintained within transparent agar plates. The fungi were exposed to UVB three times daily for 7 days from either the observe or the reverse side during incubation. The wavelength spectrum was in the range of 310-315 nm, single doses were between 0.0018 and 0.432 J cm(-2). After 7 days the morphology and growth direction of C. albicans cells were determined microscopically. All six strains showed a common and dose-dependent response to UVB irradiation: the progression of hyphal growth was inhibited, no phototropic effects were seen and as a new finding an increased formation of blastospores was observed. We conclude that an irradiation of human skin colonized by C. albicans with doses of UVB that can occur under natural or artificial conditions is unlikely to trigger skin invasion by C. albicans.
journal_name
Mycosesjournal_title
Mycosesauthors
Brasch J,Kay Cdoi
10.1111/j.1439-0507.2005.01169.xsubject
Has Abstractpub_date
2006-01-01 00:00:00pages
1-5issue
1eissn
0933-7407issn
1439-0507pii
MYC1169journal_volume
49pub_type
杂志文章相关文献
MYCOSES文献大全abstract::The annual incidence of cryptococcosis during 1981-2000 was determined in subscribers of a large integrated health care program in Northern California and in those among them who were HIV positive. The incidence of cryptococcosis had been measured in this setting in the previous decade. The 20-year incidence per milli...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2004.01082.x
更新日期:2005-03-01 00:00:00
abstract::A 29-year-old woman with swelling, multiple nodules and discharging sinuses of her right foot is presented. A single nodule on the sole was excised 15 years ago and since then she has had recurrent attacks of swelling and discharging sinuses that improved partially with antibiotics. Magnetic resonance images (MRI) rev...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2006.01260.x
更新日期:2006-09-01 00:00:00
abstract::Despite appropriate antimicrobial and antifungal therapy (amphotericin B), a disseminated infection with Fusarium oxysporum in a 75-year-old immunocompromised patient (acute myeloid leukaemia, minimal leucocyte count of 0.5 giga l-1) led rapidly to death. A similarly fatal course of an F. oxysporum infection has been ...
journal_title:Mycoses
pub_type: 信件
doi:10.1046/j.1439-0507.2000.00590.x
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:Microsporum canis is a zoophilic species, found to be the most frequently isolated species in animals. M. canis causes sporadic outbreaks of infections in humans, such as the one that occurred in Canada, where more than 1000 human cases were detected over an 8-year period. Despite the medical importance of M...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12986
更新日期:2019-11-01 00:00:00
abstract::In 20 HIV-patients (17 male homosexuals, 1 male and 1 female i.v. drug abuser and 1 female patient with M. Willebrand-Jürgens) Candida esophagitis was diagnosed by esophagogastroduodenoscopy. Clinically they presented retrosternal pain or an exacerbation of oral candidosis under local antimycotics. The diagnosis of Ca...
journal_title:Mycoses
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Cryptococcal meningitis has fatality rates of 40%-70%, resulting in 200 000 deaths each year. The best outcomes are achieved with amphotericin combined with flucytosine but flucytosine is expensive and unavailable where most disease occurs. More effective and affordable treatments are needed. Tamoxifen, a se...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12955
更新日期:2019-09-01 00:00:00
abstract::The effect of four media or media combinations on the growth and the in vitro susceptibility to amphotericin B, 5-fluorocytosine, fluconazole and itraconazole of 51 isolates of Cr. neoformans was studied. The drug concentration producing a 50% decrease in OD405 (IC50) was determined in microtiter format. The following...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1996.tb00125.x
更新日期:1996-05-01 00:00:00
abstract::A valid and reliable measure that captures onychodystrophy disease severity is important for both clinical and research applications. Three hundred and twenty-two patients at two Veterans Affairs Medical Centers with clinical evidence of onychodystrophy suggesting onychomycosis (at least 25% in a distal subungual patt...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2007.01444.x
更新日期:2008-01-01 00:00:00
abstract::Disseminated histoplasmosis (DH) is the most current revelation mode of AIDS in French Guiana. We describe the clinical and paraclinical presentation of DH, diagnostic tools, evolution and factors associated with 1-year mortality in HIV-infected patients from western French Guiana. Microbiologically proven AIDS-relate...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12293
更新日期:2015-03-01 00:00:00
abstract::Candida species constitute the majority of nosocomial fungal pathogens in non-neutropenic patients. Candida infections are still connected with substantial mortality. Recent epidemiological observations indicate a shift to non-albicans species, especially because of a rise of infections caused by C. glabrata, which fr...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0507.2008.01527.x
更新日期:2008-01-01 00:00:00
abstract::This retrospective study reviews the occurrence and treatment of various forms of tinea capitis at the out-patient clinic for Dermatology and Pediatric Dermatology of the University Hospital Sophia/Dijkzigt over the period 1977-1988. Tinea capitis was diagnosed in 64 children. Trichophyton violaceum was the pathogen m...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.1990.33.1.46
更新日期:1990-01-01 00:00:00
abstract::Despite several chemotherapeutic and preventative advances, opportunistic fungal infections remain common unintended consequences of cancer treatment. Currently, cancer patients spend most of their time between treatments at home, where they can inadvertently come across potential hazards from environmental and food s...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/myc.12167
更新日期:2014-06-01 00:00:00
abstract::This is an observational-retrospective study comparing the real-world outcomes associated with posaconazole vs itraconazole as prophylaxis treatments. Two hundred and ninety-three patient admissions attributable to 174 patients were included in the study. Patients were treated with itraconazole (n = 114 admissions; 39...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12728
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Candida glabrata is the third leading cause of candidaemia in Turkey; however, the data regarding antifungal resistance mechanisms and genotypic diversity in association with their clinical implication are limited. OBJECTIVES:To assess genotypic diversity, antifungal susceptibility and mechanisms of drug re...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.13104
更新日期:2020-09-01 00:00:00
abstract::The aim was to evaluate the in vitro activity of voriconazole compared with those of amphotericin B, itraconazole and fluconazole against 132 bloodstream isolates of Candida non-albicans and Saccharomyces cerevisiae species. The minimal inhibitory concentrations (MICs) were determined by an adapted National Committee ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2004.00971.x
更新日期:2004-06-01 00:00:00
abstract::The serological responses to Cryptococcus neoformans proteins of blood donors and HIV patients with active cryptococcosis from a tropical region were investigated in this study. Exposure to C. neoformans, an organism ubiquitous in the environment, contributes to the antibody responses observed in the blood donors. IgG...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2008.01549.x
更新日期:2009-03-01 00:00:00
abstract:UNLABELLED:This multicentre observational study evaluated the feasibility, efficacy and toxicity of antifungal combination therapy (combo) as treatment of proven or probable invasive fungal diseases (IFDs) in patients with haematological malignancies. Between January 2005 and January 2010, 84 cases of IFDs (39 proven a...
journal_title:Mycoses
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/myc.12161
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:The incidence of fungal keratitis has increased in recent years. While the epidemiology and clinical roles of various Candida and Fusarium species have been relatively well-identified in infections of the eye, data regarding keratitis caused by Aspergillus species are scant. Accurate and rapid diagnosis is i...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12855
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Patients undergoing allogeneic stem cell transplantation (aSCT) are at high risk to develop an invasive fungal disease (IFD). Optimisation of antifungal prophylaxis strategies may improve patient outcomes and reduce treatment costs. OBJECTIVES:To analyse the clinical and economical impact of using continuou...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.13232
更新日期:2020-12-22 00:00:00
abstract::Mucormycosis mostly affects immunocompromised patients and is associated with a high morbidity and mortality despite currently available treatments. In that context, combination therapy might be the key to a better outcome for these patients. Purpose of this review is to summarise and to discuss the current combinatio...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/myc.12909
更新日期:2019-09-01 00:00:00
abstract::Terbinafine was remarkably effective in tinea barbae due to Trichophyton rubrum on the cheek in front of the right ear in a 75-year-old man. This patient also showed tinea pedis and unguium, but these were due to Trichophyton mentagrophytes and were unrelated to the tinea in the cheek. This patient showed an atypical ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.1998.tb00382.x
更新日期:1998-01-01 00:00:00
abstract::Between May 1, 1988 and January 1, 1990, 10 patients were treated for Candida peritonitis. Origins of the infections were lesions and perforations of the gastrointestinal tract. Risk factors promoting the disease were tumours, diabetes mellitus and extensive antibiotic therapy. The mean classification by the APACHE sc...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.1990.33.9-10.441
更新日期:1990-09-01 00:00:00
abstract::A mycological survey was conducted on non-neutropenic patients in three distinct intensive care units in two hospitals in Marseille (France) from November 1993 to November 1995. Candida albicans positive cultures from 62 patients were included in this study. Every first isolate of each patient was typed by multilocus ...
journal_title:Mycoses
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1439-0507.2000.00552.x
更新日期:2000-01-01 00:00:00
abstract::To determine the ecological and epidemiological significance of pigeon excrement in cryptococcosis in Mexico City, 251 samples of pigeon droppings were studied. These were collected from houses, public buildings, churches, parks and pigeon nests. Each sample was suspended 1:10 in isotonic saline solution and then cult...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.1994.37.9-10.325
更新日期:1994-09-01 00:00:00
abstract::The mould collection of the Centraalbureau voor Schimmelcultures, Baarn, The Netherlands, was screened for isolates originating from warm-blooded animals. The range of species indicates that distribution of clinically relevant, pathogenic or opportunistic strains over the fungal kingdom is non-random. Some opportunist...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0507.1992.tb00849.x
更新日期:1992-09-01 00:00:00
abstract::Although case series of talaromycosis have been reported in China, their detailed clinical and microbiological characteristics have never been systematically profiled. In this study, we report the clinical characteristics, molecular epidemiology, rapid identification and antifungal susceptibilities of talaromycosis in...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/myc.12887
更新日期:2019-05-01 00:00:00
abstract::A 36-year-old HIV-infected male patient presented with relapsing fever episodes to 39 degrees C, night sweats and weight loss. Computerized tomography of the abdomen showed enlarged multiple lymph nodes. After surgical resection of multiple lymph nodes, disseminated infection with Histoplasma capsulatum was diagnosed....
journal_title:Mycoses
pub_type: 信件
doi:10.1046/j.1439-0507.1999.00262.x
更新日期:1999-04-01 00:00:00
abstract::Histoplasmosis is an important systemic mycosis in the Americas, Asia, and Africa. Increasingly cases are recognised in nonendemic areas. Proper management requires recognition of the clinical syndromes caused by Histoplasma capsulatum infection, familiarity with the uses and limitations of the diagnostic tests, an un...
journal_title:Mycoses
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0507.2006.01253.x
更新日期:2006-07-01 00:00:00
abstract::Fifty-four patients with human immunodeficiency virus (HIV) infection were studied to assess the load of oral carriage of Candida spp. The mean oral Candida carriage density (30,305.93 +/- 56,643.93 CFU ml(-1)) in HIV patients was significantly higher than that seen in the control population (93.48 +/- 358.48 CFU ml(-...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2008.01534.x
更新日期:2009-01-01 00:00:00
abstract::Adherence of Candida has been implicated as the first step in the pathogenesis of oral candidosis, and germ tube formation, a contributory attribute. While chlorhexidine gluconate is by far the most common antiseptic mouthwash prescribed in dentistry, its intraoral concentration fluctuates considerably because of the ...
journal_title:Mycoses
pub_type: 杂志文章
doi:10.1111/j.1439-0507.2010.01915.x
更新日期:2011-09-01 00:00:00