Detection of IgM and IgG antibodies to Cryptococcus neoformans proteins in blood donors and HIV patients with active cryptococcosis.

Abstract:

:The serological responses to Cryptococcus neoformans proteins of blood donors and HIV patients with active cryptococcosis from a tropical region were investigated in this study. Exposure to C. neoformans, an organism ubiquitous in the environment, contributes to the antibody responses observed in the blood donors. IgG responses to cryptococcal proteins were stronger than IgM responses in most sera tested in this study. A 53-kDa cryptococcal protein fragment was identified as the most immunoreactive protein on the IgM immunoblots of both blood donors and patients. Overall, there was no obvious difference in IgG responses of patients when compared with blood donors. Some immunogenic protein fragments (27.5, 76, 78 and 91.5 kDa) were detected at least two times more frequently on IgM immunoblots of patients compared with those of blood donors. It is yet to be investigated whether the proteins identified in this study may have any potential to be used as biomarker for cryptococcosis.

journal_name

Mycoses

journal_title

Mycoses

authors

Chai HC,Tay ST

doi

10.1111/j.1439-0507.2008.01549.x

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

166-70

issue

2

eissn

0933-7407

issn

1439-0507

pii

MYC1549

journal_volume

52

pub_type

杂志文章

相关文献

MYCOSES文献大全
  • Evaluation and comparison of the growth and viability of yeast-like cells of Paracoccidioides brasiliensis.

    abstract::The growth and viability of two Paracoccidioides brasiliensis strains were evaluated in PYG and MMcM media containing no boric acid. The two P. brasiliensis strains exhibited a similar growth pattern in PYG medium, which was considered to be good compared with the growth curves in defined MMcM medium without boric aci...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1996.tb00108.x

    authors: de Moraes Borba C,Mendes da Silva AM,Cunha de Oliveira P

    更新日期:1996-03-01 00:00:00

  • Posaconazole: clinical pharmacokinetics and drug interactions.

    abstract::Posaconazole represents an antifungal extended-spectrum triazole whose absolute bioavailability following oral drug administration is considerably variable. Special conditions including increased gastric pH values, malabsorption syndrome, diarrhoea, intake on an empty stomach and some concomitantly administered potent...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2010.01984.x

    authors: Lipp HP

    更新日期:2011-01-01 00:00:00

  • Yeast associated with human infections in south-eastern Nigeria.

    abstract::A total of 1921 specimens from nine clinical sources were examined by direct microscopy and culture to recover yeast associated with human infection. Identification of yeast was based on their carbon assimilation patterns, using API 20C AUX and ID 32 C (bioMérieux, France) commercial kits. A total of 178 specimens (9....

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2006.01282.x

    authors: Abia-Bassey LN,Utsalo SJ

    更新日期:2006-11-01 00:00:00

  • In vitro activities of 15 antifungal drugs against a large collection of clinical isolates of Microsporum canis.

    abstract:BACKGROUND:Microsporum canis is a zoophilic species, found to be the most frequently isolated species in animals. M. canis causes sporadic outbreaks of infections in humans, such as the one that occurred in Canada, where more than 1000 human cases were detected over an 8-year period. Despite the medical importance of M...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12986

    authors: Abastabar M,Jedi A,Guillot J,Ilkit M,Eidi S,Hedayati MT,Shokohi T,Daie Ghazvini R,Rezaei-Matehkolaei A,Katiraee F,Javidnia J,Ahmadi B,Badali H

    更新日期:2019-11-01 00:00:00

  • Xanthothecium peruvianum isolated from human stratum corneum: A case report, characterisation and short review that suggest emendation of Arachnomyces peruvianus.

    abstract::From stratum corneum samples of a palmar eczema, a fungus was isolated that developed white colonies with a yellowish dark reverse, suggestive of dermatophytes. The isolate produced numerous chlamydospores and sparse aleuroconidia, was resistant to cycloheximide, grew well on human stratum corneum samples and was posi...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/myc.12613

    authors: Brasch J,Beck-Jendroscheck V,Voss K,Yurkov A,Stchigel AM,Gräser Y

    更新日期:2017-07-01 00:00:00

  • Dermatophytosis in schoolchildren in Ekpoma, Nigeria.

    abstract::Of 1400 pupils from two public primary schools in Ekpoma, Edo State, Nigeria, who were screened for dermatophyte infection, 188 (13.4%) were infected. The causative agents isolated included Microsporum audouinii in 88 (46.8%), Trichophyton mentagrophytes in 48 (25.5%), T. rubrum in 40 (21.3%), T. tonsurans in four (2....

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1996.tb00143.x

    authors: Enweani IB,Ozan CC,Agbonlahor DE,Ndip RN

    更新日期:1996-07-01 00:00:00

  • Tinea pedis acquired in mosques?

    abstract::We present four cases of interdigital tinea pedis in Italian tourists which was probably acquired in Turkish mosques and holy Muslim places. In all patients mycological examinations were positive for Trichophyton rubrum. All patients were successfully treated with bifonazole cream (one application/day for three weeks)...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12775

    authors: Veraldi S,Esposito L,Gorani A

    更新日期:2018-11-01 00:00:00

  • Case of femoral pseudarthrosis due to Scedosporium apiospermum in an immunocompetent patient with successful conservative treatment and review of literature.

    abstract::Scedosporium apiospermum is a ubiquitous filamentous fungus, commonly found in soil, sewage and polluted waters. It is rarely pathogenic but can cause a broad spectrum of clinical diseases, which can be localised or disseminate to distant organs. The disseminated form of the disease is mostly seen among immunocompromi...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/myc.12739

    authors: Dinh A,Demay O,Rottman M,Gaudot F,Bougnoux ME,Bouchand F,Coignard H,Rouzaud C,Davido B,Duran C,Nich C

    更新日期:2018-06-01 00:00:00

  • Anti-Malassezia furfur antibodies in the population.

    abstract::The authors carried out research into anti-Malassezia precipitating antibodies in the population, specifying the distribution by age and sex. A total of 868 serum specimens from subjects of both sexes, aged between 0 and 80 years, were studied. An immunoelectroprecipitation reaction was used using a M. furfur culture ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1998.tb00337.x

    authors: Faggi E,Pini G,Campisi E,Gargani G

    更新日期:1998-09-01 00:00:00

  • Genetic diversity and antifungal susceptibility of Fusarium isolates in onychomycosis.

    abstract::Fusarium species have emerged as an important human pathogen in skin disease, onychomycosis, keratitis and invasive disease. Onychomycosis caused by Fusarium spp. The infection has been increasingly described in the immunocompetent and immunosuppressed hosts. Considering onychomycosis is a difficult to treat infection...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12638

    authors: Rosa PD,Heidrich D,Corrêa C,Scroferneker ML,Vettorato G,Fuentefria AM,Goldani LZ

    更新日期:2017-09-01 00:00:00

  • Empirical caspofungin therapy in clinical practice for suspected invasive fungal disease in adults with acute lymphoblastic leukaemia.

    abstract::Patients with acute lymphoblastic leukaemia (ALL) after cytotoxic chemotherapy or haematopoietic stem cell transplantation (HSCT) are at risk for life-threatening invasive fungal disease (IFD). The aim was to evaluate the characteristics, antifungal therapy and outcome of adult patients with ALL after chemotherapy or ...

    journal_title:Mycoses

    pub_type: 杂志文章,多中心研究

    doi:10.1111/myc.12277

    authors: Kiehl MG,Egerer G,Engelhardt M,Gross B

    更新日期:2015-02-01 00:00:00

  • Stress response in medically important Mucorales.

    abstract::Mucorales are saprobes, ubiquitously distributed and able to infect a heterogeneous population of human hosts. The fungi require robust stress responses to survive in human host. We tested the growth of Mucorales in the presence of different abiotic stress. Eight pathogenic species of Mucorales, including Rhizopus arr...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12512

    authors: Singh P,Paul S,Shivaprakash MR,Chakrabarti A,Ghosh AK

    更新日期:2016-10-01 00:00:00

  • A universal DNA extraction and PCR amplification method for fungal rDNA sequence-based identification.

    abstract::Accurate identification of fungal pathogens using a sequence-based approach requires an extraction method that yields template DNA pure enough for polymerase chain reaction (PCR) or other types of amplification. Therefore, the objective of this study was to develop and standardise a rapid, inexpensive DNA extraction p...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12208

    authors: Romanelli AM,Fu J,Herrera ML,Wickes BL

    更新日期:2014-10-01 00:00:00

  • Fluconazole: optimized antifungal therapy based on pharmacokinetics.

    abstract::Fluconazole, a triazole, inhibits synthesis of ergosterol. The key enzyme of antifungal activity is C-14-Demethylase, which itself depends on Cytochrom-P-450. So drugs that inhibit or induce this enzyme lead to interactions that have to be considered when dosing fluconazole. Oral bioavailability is more than 90% after...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0507.2002.tb04768.x

    authors: Silling G

    更新日期:2002-01-01 00:00:00

  • Case report. Rosacea-like Tinea incognito.

    abstract::We report a case of dermatophytosis of the face due to Microsporum canis that was exacerbated and altered clinically by a long-term application of topical corticosteroids. We considered this case a rosacea-like tinea incognito of the beard area. ...

    journal_title:Mycoses

    pub_type: 信件

    doi:10.1046/j.1439-0507.2002.00742.x

    authors: Gorani A,Schiera A,Oriani A

    更新日期:2002-04-01 00:00:00

  • [Pharmacokinetics of itraconazole].

    abstract::Itraconazole is a lipophilic triazole antifungal with a broad spectrum of activity. Most of the important fungal pathogens respond to itraconazole concentrations of 100 ng/ml. Therefore, itraconazole is suitable for treatment of a variety of systemic mycoses, as aspergillosis, cryptococcosis, candidosis as well as non...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:

    authors: Cauwenbergh G

    更新日期:1994-01-01 00:00:00

  • Comparison of 12 liquid media for germ tube production of Candida albicans and C. tropicalis.

    abstract::Infections caused by yeast of the genus Candida are the most common fungal infections, being Candida albicans the most common isolated species among them. The rapid identification of this yeast is mostly based on the production of germ tube in human or animal serum. This study describes the use of 12 different liquid ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2007.01359.x

    authors: Hilmioglu S,Ilkit M,Badak Z

    更新日期:2007-07-01 00:00:00

  • Antifungal susceptibility of Candida species isolated from patients with candidemia in southern Taiwan, 2007-2012: impact of new antifungal breakpoints.

    abstract::The Clinical and Laboratory Standard Institute (CLSI) revised the clinical breakpoints (CBPs) for the azoles and echinocandins against Candida species in 2012. We aimed to report the epidemiology of candidemia and antifungal susceptibility of Candida species and evaluate the impact of new CBPs on antifungal susceptibi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12553

    authors: Chen YC,Kuo SF,Chen FJ,Lee CH

    更新日期:2017-02-01 00:00:00

  • Osteomyelitis due to Cryptococcus neoformans in advanced age. Case report and review of literature.

    abstract::In an 84-year-old man cryptococcosis with a pronounced osteomyelitic course (involvement of a rib, two thoracic vertebrae, the sacrum and a femur) was diagnosed histologically post mortem, thus directing attention to cryptococcosis in advanced age. The presumptive chronic course of the Cryptococcus neoformans (Cr. n.)...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/myc.1990.33.4.157

    authors: Kromminga R,Staib F,Thalmann U,Jautzke G,Seibold M,Hochrein H,Witt H,Bürger H

    更新日期:1990-04-01 00:00:00

  • Severe fungal sclerokeratitis caused by Metarhizium anisopliae: a case report and literature review.

    abstract::To date, there has been only one published report on the infectious sclerokeratitis caused by Metarhizium anisopliae, which is an entomopathogenic fungus. Regarding corneal infection, three reports have been published to date. Although the prognoses of the corneal infections are favourable, prognosis when scleral infe...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/myc.12279

    authors: Eguchi H,Toibana T,Hotta F,Miyamoto T,Mitamura Y,Yaguchi T

    更新日期:2015-02-01 00:00:00

  • Retrospective evaluation of caspofungin therapy in invasive aspergillosis (RECAM-IA).

    abstract::To evaluate caspofungin in high-risk invasive aspergillosis (IA) patient, a retrospective review of patient characteristics, antifungal therapies and clinical outcomes on hospitalised patients at sites in Russia, Canada, Germany, and Thailand was performed. Fifty-five patients were included, six with proven and 49 wit...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2010.01861.x

    authors: Wisniewski T,Klimko N,Laverdiere M,Kiertiburanakul S,Kliasova G,Trenschel R,Kumar RN

    更新日期:2011-07-01 00:00:00

  • An atypical isolate of Paracoccidioides brasiliensis.

    abstract::An atypical strain of Paracoccidioides brasiliensis was obtained from a patient with disseminated paracoccidioidomycosis. This isolate, which has been maintained in the laboratory for 4 years by successive subcultures (30-40 days) in Fava Netto medium, produces cerebriform colonies characteristic of the yeast phase of...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1995.tb00024.x

    authors: Hamdan JS,Ferrari TC

    更新日期:1995-11-01 00:00:00

  • [Controversies in the standardization of susceptibility testing on yeasts to azole antimycotics].

    abstract::Due to the different physical-chemical conditions of the therapeutical azoles it is necessary to choose an adequate testing procedure. In the group of azoles caused by its hydrophilia fluconazole susceptibility testing can be handled easily. However it is not possible to take the same test conditions for itraconazole ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1996.tb00523.x

    authors: Tintelnot K,Seibold M

    更新日期:1996-01-01 00:00:00

  • Onychomycosis is no longer a rare finding in children.

    abstract::Onychomycosis was considered uncommon in children. This survey was carried out to estimate the frequency of fungal nail infections in children and adolescents (0-18 years of age) attending our clinic in the last decade and gain more insight into the aetiology and clinics of this entity in the paediatric age group. Thi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2005.01186.x

    authors: Lange M,Roszkiewicz J,Szczerkowska-Dobosz A,Jasiel-Walikowska E,Bykowska B

    更新日期:2006-01-01 00:00:00

  • Preparation of antigens from Trichophyton mentagrophytes using a new semi-solid culture medium and their characterization by SDS-PAGE and immunological techniques.

    abstract::A new semi-solid culture medium was developed by substituting the agar in Sabouraud glucose medium by Lutrol FC 127 (BASF, Ludwigshafen, Germany). This culture medium can be liquefied by cooling it down from the incubation temperature to 5-10 degrees C, thus allowing the full harvest of fungal mycelium without any con...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.1992.tb00893.x

    authors: Garg AP,Müller J

    更新日期:1992-11-01 00:00:00

  • First isolation of Trichophyton raubitschekii (syn. T. rubrum) in Europe.

    abstract::Trichophyton raubitschekii is a rare dermatophyte which belongs to the Trichophyton rubrum species complex. Since 1981, only a few cases of dermatophytosis due to this anthropophilic causative agent were published. In this paper the authors report the first cases of Tinea corporis caused by Trichophyton raubitschekii ...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:

    authors: Tietz HJ,Hopp M,Gräser Y

    更新日期:2002-02-01 00:00:00

  • Clinical mycology in Latin America and the Caribbean: A snapshot of diagnostic and therapeutic capabilities.

    abstract::Despite the existence of endemic mycoses in Latin America and the Caribbean, in addition to a large population of patients at risk for invasive mycoses, the capability of medical centres to perform a proper diagnosis in mycology has not been studied in the region. Moreover, availability of antifungal drugs in the regi...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.12890

    authors: Falci DR,Pasqualotto AC

    更新日期:2019-04-01 00:00:00

  • Detection of Candida dubliniensis in oropharyngeal samples from human immunodeficiency virus infected and non-infected patients and in a yeast culture collection.

    abstract::The incidence of Candida dubliniensis in oropharyngeal swabs of 132 human immunodeficiency virus (HIV)-positive and 89 HIV-negative patients was determined. The samples were plated onto CHROMagar Candida medium and 82 strains, presumptively identified as C. albicans or C. dubliniensis, were further investigated (tempe...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/j.1439-0507.2005.01129.x

    authors: Faggi E,Pini G,Campisi E,Martinelli C,Difonzo E

    更新日期:2005-05-01 00:00:00

  • Unilateral renal phaeohyphomycosis due to Bipolaris spicifera in an immunocompetent child - rare case presentation and review of literature.

    abstract::Phaeohyphomycosis refers to infections caused by phaeoid fungi that can have an aggressive course in normal hosts. We report a case of left-sided renal phaeohyphomycosis due to Bipolaris spicifera in a 7-year-old immunocompetent male child. He presented with fever, dysuria, nausea, vomiting and flank pain. Examination...

    journal_title:Mycoses

    pub_type: 杂志文章,评审

    doi:10.1111/myc.12335

    authors: Kaur R,Bala K

    更新日期:2015-07-01 00:00:00

  • Geographical distribution of mycetoma cases in senegal over a period of 18 years.

    abstract:BACKGROUND:Mycetoma is a pathological process in which fungal or actinomycotic agents of exogenous origin produce grains. In the absence of data on the global burden, it is important to map mycetoma cases, which are useful to implement control strategies. OBJECTIVE:The objective of this study was to map mycetoma cases...

    journal_title:Mycoses

    pub_type: 杂志文章

    doi:10.1111/myc.13037

    authors: Badiane AS,Ndiaye M,Diongue K,Diallo MA,Seck MC,Ndiaye D

    更新日期:2020-03-01 00:00:00