Yeast associated with human infections in south-eastern Nigeria.

Abstract:

:A total of 1921 specimens from nine clinical sources were examined by direct microscopy and culture to recover yeast associated with human infection. Identification of yeast was based on their carbon assimilation patterns, using API 20C AUX and ID 32 C (bioMérieux, France) commercial kits. A total of 178 specimens (9.3%) were positive for yeast. Most of the yeast isolates were recovered from urine samples and genital swabs. Prevalence was significantly higher in women (14.7%) than in men (1.4%) (P < 0.05). The age group 21-30 years recorded the highest prevalence of yeast infection (65.2%) followed by age group 11-20 years (16.9%) and > 40 years (9.0%). When genital samples were considered, prevalence was significantly higher in the age group 21-30 years than that in older ones (P < 0.05). Isolates recovered included seven species of Candida and Trichosporon inkin. C. albicans accounted for the highest number of isolates (128) followed by C. tropicalis (23) and C. parapsilosis (9). Two isolates each of C. famata and C. norvegensis were recorded and are reported for the first time in Nigeria. The two isolates of T. inkin were recovered from perianal lesions and are also reported for the first time from Nigeria. C. albicans, C. glabrata, C. parapsilosis and C. krusei were found to be the most common yeast species that act as agents of human disease in south-eastern Nigeria.

journal_name

Mycoses

journal_title

Mycoses

authors

Abia-Bassey LN,Utsalo SJ

doi

10.1111/j.1439-0507.2006.01282.x

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

510-5

issue

6

eissn

0933-7407

issn

1439-0507

pii

MYC1282

journal_volume

49

pub_type

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