The relation between chronic obstructive pulmonary disease and coronary collateral vessels.


:Coronary collateral vessels can provide a perfusion reserve in case of increased myocardial oxygen demand. Development of coronary collateral vessels (CCV) is triggered by the pressure gradient between the coronary bed of arteries caused by an obstruction and myocardial ischemia. Myocardial hypoxia can facilitate development of CCVs. There is a chronic hypoxemia in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to evaluate the effect of COPD on CCVs. The study included 98 patients with COPD who underwent coronary angiography. Those patients in whom coronary angiography is normal or severity of coronary artery stenosis in thought not to be sufficient for the development of CCVs (<80%) were excluded from the study. A total of 98 patients (mean age, 62 +/-9 years) met the criteria for the COPD group. For case-control matching, 98 consecutive without COPD patients (mean age 62 +/-10) who had one or more diseased vessels with 80% or greater stenosis were included in the control group. The CCVs were graded according to the Rentrop scoring system, and the collateral score was calculated by summing the Rentrop numbers of every patient. The mean number of diseased vessels in patients with COPD and without COPD were 1.61 +/-0.69 and 1.77 +/-0.89 (p=0.155), respectively. The mean collateral score was 2.15 +/-2.03 in the COPD group and 1.32 +/-1.54 in the control group. After confounding variables were controlled for, the collateral score in patients with COPD group was significantly different from that in patients without COPD group (p=0.002). These findings suggest that CCV development is better in patients with COPD than in those patients without COPD. Thus, COPD may be an important factor affecting CCV development, which may be related to the presence of chronic hypoxemia in patients with COPD.






Topsakal R,Eryol NK,Abaci A,Oymak S,Ozdoğru I,Yilmaz Y,Seyfeli E,Oğuzhan A,Ergin A




Has Abstract


2005-11-01 00:00:00












  • Electrophysiologic properties of ethacrynic acid in man.

    abstract::Ethacrynic acid is a potent oral diuretic and saluretic agent. It has been used extensively in the treatment of heart failure and its effects on cardiovascular dynamics are well established. The clinical relief of the symptoms of pulmonary congestion frequently precedes any demonstrable diuretic effect suggesting that...


    pub_type: 杂志文章


    authors: Gould L,Gopalaswamy C,Chandy F,Abdou O

    更新日期:1983-11-01 00:00:00

  • Methodological issues in the quantitative assessment of quality of life.

    abstract::The term quality of life can be identified in Aristotle's classical writings of 330 BC. In his Nichomachian ethics he recognises the multiple relationships between happiness, well-being, "eudemonia" and quality of life. Historically the concept of quality of life has undergone various interpretations. It involves pers...


    pub_type: 社论


    authors: Panagiotakos DB,Yfantopoulos JN

    更新日期:2011-10-01 00:00:00

  • Circumferential spontaneous coronary artery dissection in an elderly man: a case report.

    abstract::An 82-year-old man developed acute inferior myocardial infarction. Emergent coronary angiography demonstrated thrombotic occlusion in the right coronary artery. Intracoronary thrombolytic therapy was performed with successful recanalization. However, circumferential dissection with luminal stenosis was revealed at the...


    pub_type: 杂志文章


    authors: Koga T,Sakamoto A,Nakamura Y,Kawazoe N,Sadoshima S,Onoyama K,Fujishima M

    更新日期:1998-01-01 00:00:00

  • Preservation of skin vasoconstrictor responses in chronic atherosclerotic peripheral vascular disease.

    abstract::Peripheral neuropathy is often found in ischemic limbs with nondiabetic atherosclerotic peripheral vascular disease (PVD). Sensory symptoms such as burning pain are common in severely ischemic limbs, and sympathectomy has been undertaken for ischemic rest pain. The authors assessed noninvasive quantitative skin vasomo...


    pub_type: 杂志文章


    authors: Nukada H,van Rij AM,Packer SG,Patterson A

    更新日期:1998-03-01 00:00:00

  • The role of antiendothelial cell antibodies in the development and follow-up of coronary and peripheral arterial diseases.

    abstract::Occlusive lesions in the arterial endothelium are often caused by formation of intimal hyperplasia and fibrinoid necrosis. The objective of this study was to investigate the association between antiendothelial cell antibodies (AECAs) and the development of coronary artery disease (CAD) and peripheral artery disease (P...


    pub_type: 杂志文章


    authors: Aslim E,Hakki Akay T,Bastürk B,Ozkan S,Gültekin B,Ozcobanoglu S,Sirvan S,Aslamaci S

    更新日期:2008-04-01 00:00:00

  • The natural history of unexpected Doppler mitral regurgitation.

    abstract::It is common for patients to be diagnosed as having valvular regurgitation by Doppler echo when no such murmur has been heard by the referring clinician. To test the hypothesis that such patients have clinically unimportant heart disease, the authors evaluated the records of 213 consecutive men in whom mitral regurgit...


    pub_type: 杂志文章


    authors: Kinney EL,Wright RJ

    更新日期:1989-05-01 00:00:00

  • Effects of atorvastatin on vascular intimal hyperplasia: an experimental rodent model.

    abstract:INTRODUCTION:Vascular intimal hyperplasia is associated with increased mortality and morbidity. The authors investigated the effects of atorvastatin on vascular intimal hyperplasia. MATERIALS AND METHODS:Rats were divided into 4 groups. Groups 1, 2, and 3 had experimental aortic injury and received intraperitoneal inj...


    pub_type: 杂志文章


    authors: Aydin U,Ugurlucan M,Gungor F,Ziyade S,Inan B,Banach M,Kalko Y,Yasar T

    更新日期:2009-06-01 00:00:00

  • Multiple lead ECG submaximal treadmill exercise tests in angiographically documented coronary heart disease.

    abstract::One hundred patients underwent submaximal exercise tolerance testing and coronary cineangiography. Sixty-six percent of the exercise tests were diagnostic including 48 positive and 18 negative tests; 34 patients had indeterminate test results. The occurrence of exercise induced ventricular premature beats was not rela...


    pub_type: 杂志文章


    authors: Tucker SC,Kemp VE,Holland WE,Horgan JH

    更新日期:1976-03-01 00:00:00

  • Coronary flow reserve measurements with a new Judkins-style Doppler angiographic catheter.

    abstract::The authors assessed whether measurements obtained by Judkins-style Doppler catheters are comparable to those achieved with the intracoronary Doppler technique in 42 patients with normal coronary arteries on angiography (19 syndrome X and 23 heart transplant patients). Resting coronary flow velocity and response to a ...


    pub_type: 杂志文章


    authors: Chauhan A,Mullins PA,Thuraisingham S,Taylor G,Petch MC,Schofield PM

    更新日期:1993-12-01 00:00:00

  • Common carotid artery wall properties in Takayasu's arteritis.

    abstract::The vessel wall properties of the common carotid artery have been noninvasively and quantitatively assessed with an ultrasonic instrument. Stiffness parameter beta, which represents the mechanical properties of the vessel, was calculated from the relationship between blood pressure and the diameter of the artery. Ther...


    pub_type: 杂志文章


    authors: Wada T,Kodaira K,Fujishiro K,Maie K,Tsukiyama E,Fukumoto T,Uchida T,Yamazaki S

    更新日期:1996-07-01 00:00:00

  • Clinical efficacy of micronized purified flavonoid fraction (MPFF) in edema.

    abstract::Swelling is one of the most frequent complaints of patients in daily clinical practice; leg edema is its objective confirmation. It can be associated with several diseases. Micronized purified flavonoid fraction (MPFF) is a phlebotropic drug commonly used to treat the signs and symptoms associated with chronic venous ...


    pub_type: 杂志文章


    authors: Olszewski W

    更新日期:2000-01-01 00:00:00

  • Left ventricular remodeling and function in adult aortic stenosis.

    abstract::The aim of this study was to analyze the left ventricular (LV) geometric changes occurring in chronic pressure overload due to valvular aortic stenosis (AS). Fifty-six adult patients (30 women, 26 men, mean age seventy-two +/- nine years, range forty-five to eighty-five years) with isolated AS (mean valve area by Dopp...


    pub_type: 杂志文章


    authors: Faggiano P,Rusconi C,Ghizzoni G,Sabatini T

    更新日期:1994-12-01 00:00:00

  • Prognostic improvement by multidisciplinary therapy in patients with critical limb ischemia.

    abstract::Although limb salvage rate has improved in critical limb ischemia (CLI), an improvement in CLI prognosis has been scarcely reported. Multidisciplinary therapy (MT) including revascularization, wound bed preparation, treatment of comorbidity, and education of patients with CLI may improve prognosis. The aim of this stu...


    pub_type: 杂志文章


    authors: Hioki H,Miyashita Y,Miura T,Ebisawa S,Motoki H,Izawa A,Tomita T,Koyama J,Ikeda U

    更新日期:2015-02-01 00:00:00

  • A young girl with vasospastic angina associated with mutation in endothelial nitric oxide synthase gene--a case report.

    abstract::A 13-year-old girl was successfully recuperated from cardiopulmonary arrest shortly after running 80 m in a competition. The electrocardiogram, echocardiogram and 123I-MIBG myocardial scintigraphic imaging indicated myocardial ischemia in the anteroseptal wall of the left ventricle. Coronary angiography during the rec...


    pub_type: 杂志文章


    authors: Fukuda N,Kurokawa S,Maeda K,Iseki S,Takahasi M,Niwano H,Nakazato K,Niwano S,Kurosawa T,Izumi T

    更新日期:2003-03-01 00:00:00

  • Reversal of gangrenous lesions in the blue toe syndrome with lovastatin--a case report.

    abstract::A seventy-six-year-old man with ischemic heart disease, peripheral vascular disease, and chronic renal failure developed bilateral cyanotic toes, which upon muscle biopsy, were shown to be caused by atheromatous emboli. The probable source was atheromatosis of the abdominal aorta. The toes became gangrenous, but surgi...


    pub_type: 杂志文章


    authors: Cabili S,Hochman I,Goor Y

    更新日期:1993-10-01 00:00:00

  • Efficacy and tolerability of liposomal heparin spraygel as an add-on treatment in the management of superficial venous thrombosis.

    abstract::Superficial venous thrombosis usually resolves spontaneously in a few weeks. In most cases, treatment includes peroral analgesics or nonsteroidal anti-inflammatory drugs accompanied by the recommendation to wear elastic stockings and perform regular mild ambulation. In contrast to this "standard treatment," a recent A...


    pub_type: 杂志文章,随机对照试验


    authors: Katzenschlager R,Ugurlouglu A,Sipos G,Bihari I,Anyova EB,Hirschl M,Maruszynski M,Noszczyk W,Rybak Z,Cencora A

    更新日期:2007-04-01 00:00:00

  • The antihypertensive effects of a pure and selective serotonin-receptor blocking agent (R 41 468) in elderly patients.

    abstract::In a first experiment, an acute intravenous administration of 10 mg R 41 468, a pure serotonin-receptor blocking agent with high selectivity for blood vessels and thrombocytes and devoid of central effects, dramatically reduced systolic and diastolic blood pressure in 23 elderly hypertensive patients. Heart rate and c...


    pub_type: 临床试验,杂志文章


    authors: De Cree J,Leempoels J,De Cock W,Geukens H,Verhaegen H

    更新日期:1981-02-01 00:00:00

  • Relation between postpacing T wave changes and myocardial scintigraphic characteristics in patients with ventricular demand pacemaker.

    abstract::The aim of this study was to elucidate the cause of T wave changes after ventricular pacing using thallium 201 single photon emission computed tomography (Tl-SPECT). Tl-SPECT was performed in 20 patients with sick sinus syndrome who had negative T wave after ventricular pacing and had had a ventricular demand pacemake...


    pub_type: 杂志文章


    authors: Abe M,Hamada M,Matsuoka H,Shigematsu Y,Sumimoto T,Okayama H,Kawakami H,Nakata S,Hiwada K

    更新日期:1995-06-01 00:00:00

  • Classification of Aortic Stenosis by Flow and Gradient Patterns Provides Insights into the Pathophysiology of Disease.

    abstract::Different patterns of flow and valve gradients can lead to diagnostic uncertainty about the severity of aortic stenosis (AS). Consecutive patients with severe AS (valve area <1 cm(2)) underwent echocardiography and computed tomography. Patients were classified into 4 groups (high-gradient/normal flow [HGNF], high-grad...


    pub_type: 杂志文章


    authors: Bhattacharyya S,Mittal T,Abayalingam M,Kabir T,Dalby M,Cleland JG,Baltabaeva A,Rahman Haley S

    更新日期:2016-08-01 00:00:00

  • Association of 5 Well-Defined Polymorphisms in the Gene Encoding Transforming Growth Factor-β1 With Coronary Artery Disease Among Chinese Patients With Hypertension.

    abstract::We assessed the association between 5 well-defined polymorphisms of the transforming growth factor-β1 (TGFB1) gene and coronary artery disease (CAD) among patients with hypertension from northeast China. All study participants were classified into patients with CAD (n = 679) and controls (n = 686) according to angiogr...


    pub_type: 杂志文章


    authors: Xu J,Yu X,Huang C,Qin R,Peng F,Lin J,Niu W

    更新日期:2015-08-01 00:00:00

  • Enlargement of the superior thyroid artery: an unusual cause for a cervical bruit.

    abstract::An enlarged superior thyroid artery with increased blood flow to a large benign adenomatous goiter was found to be the cause of a bruit in the region of the right carotid bifurcation. We have not been able to find mention of this cause for a cervical bruit in the literature. ...


    pub_type: 杂志文章


    authors: Healy JF,Brault T

    更新日期:1984-09-01 00:00:00

  • Microcirculatory efficacy of topical treatment with aescin + essential phospholipids gel on transcutaneous PO2 in venous insufficiency.

    abstract::A gel including aescin, essential phospholipids (EPL), and heparin (EG) has been used for many years for local treatment of venous, microcirculatory alterations (varicose veins, chronic venous insufficiency). Bruises, swelling, thrombophlebitis, and contusions are effectively treated with this compound. The aim of thi...


    pub_type: 杂志文章


    authors: Cesarone MR,Belcaro G,Ippolito E,Ricci A,Ruffini M,Dugall M

    更新日期:2004-05-01 00:00:00

  • Screening for deep vein thrombosis in asymptomatic high-risk patients: a comparison between digital photoplethysmography and venous ultrasonography.

    abstract:OBJECTIVE:To determine the role of digital photoplethysmography in screening asymptomatic patients who are susceptible for developing deep vein thrombosis. METHODS:Three hundred and thirty-seven limbs in 169 patients who were high risk for development of deep vein thrombosis were assessed by ultrasonography digital ph...


    pub_type: 杂志文章


    authors: Sharif-Kashani B,Behzadnia N,Shahabi P,Sadr M

    更新日期:2009-06-01 00:00:00

  • Is color-flow duplex a good diagnostic test for detection of isolated calf vein thrombosis in high-risk patients?

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    pub_type: 杂志文章


    authors: Eskandari MK,Sugimoto H,Richardson T,Webster MW,Makaroun MS

    更新日期:2000-09-01 00:00:00

  • From Femoral to Radial Approach in Coronary Intervention.

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    pub_type: 杂志文章,评审


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    更新日期:2017-04-01 00:00:00

  • Persons with varicose veins have a high subsequent incidence of arterial disease: a population-based study in Tampere, Finland.

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    pub_type: 杂志文章


    authors: Mäkivaara LA,Ahti TM,Luukkaala T,Hakama M,Laurikka JO

    更新日期:2007-12-01 00:00:00

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    abstract::This study was undertaken to observe coronary thrombus formation serially from an antegrade perspective by means of a new thin flexible angioscope that has an inflatable balloon at the distal tip and an angulation mechanism. To test its capabilities, thrombi were induced in the left anterior descending coronary artery...


    pub_type: 杂志文章


    authors: Mizuno K,Miyamoto A,Isojima K,Kurita A,Senoo A,Arai T,Kikuchi M,Nakamura H

    更新日期:1992-02-01 00:00:00

  • Impact of Diabetes Mellitus on Critical Limb Ischemia With Below the Knee Disease: Japan Below-the-Knee Artery Treatment Subanalysis.

    abstract:BACKGROUND:A strong association exists between diabetes mellitus and critical limb ischemia. METHODS AND RESULTS:We performed endovascular therapy on 1060 limbs in 884 patients with below knee lesions only. The patients were divided into diabetes (DG) and nondiabetes groups (NDG). Limb salvage was poorer in the DG (79...


    pub_type: 杂志文章,多中心研究


    authors: Suzuki K,Iida O,Yamauchi Y,Nakano M,Soga Y,Kawasaki D,Tazaki J,Yamaoka T,Suematsu N,Shintani Y,Miyashita Y,Inoue N,Meguro T

    更新日期:2020-05-01 00:00:00

  • Pentoxifylline for intermittent claudication. A critical review.

    abstract::Pentoxifylline was first introduced in Germany twenty years ago. Today it is the best researched oral drug for intermittent claudication. A total of seventeen placebo-controlled trials could be retrieved from the world literature. The majority of these studies show that pentoxifylline will prolong the walking distance...


    pub_type: 杂志文章,评审


    authors: Ernst E

    更新日期:1994-05-01 00:00:00

  • Headache, thrombolytic therapy, and chronic subdural hemorrhage--a case report.

    abstract::Subdural hematomas are well known but infrequent complications of thrombolytic therapy. Although these are usually associated with head trauma, the authors describe a case of a patient who received a particularly aggressive thrombolytic regimen and presented six months later with complaints of nothing more than a head...


    pub_type: 杂志文章


    authors: Nathan PE,Sonenblick D,Chakote V,Wolf R,Sacchi TJ

    更新日期:1994-01-01 00:00:00