C-344T polymorphism of the aldosterone synthase gene and blood pressure in the elderly: a population-based study.

abstract：:Cardiovascular risk increases with chronological as well as biological aging, and one marker of this might be telomere length. The telomere cap is located at the end of the DNA helix and serves to protect its end. This is an evolutionary adaptation which has resulted in stabilization of the DNA strand within the chrom...

journal_title：Journal of hypertension

authors： Nilsson PM

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To verify the benefit of renin-angiotensin system blockade in hypertension, the effects of 24 weeks' losartan and ramipril treatment, both alone and in combination, on urinary albumin excretion (UAE) and circulating transforming growth factor beta1 (TGF beta1) have been evaluated in hypertensive subjects with...

journal_title：Journal of hypertension

authors： Scaglione R,Argano C,Corrao S,Di Chiara T,Licata A,Licata G

更新日期：2005-03-01 00:00:00

abstract：CONTEXT:There is a growing prevalence of cardiovascular disease (CVD) risk factors in West Africa and among its migrants to industrialized countries. Despite this, no study has reviewed CVD risk factor prevalence among West Africans in Africa and industrialized countries. OBJECTIVE:To appraise studies on the prevalenc...

journal_title：Journal of hypertension

authors： Commodore-Mensah Y,Samuel LJ,Dennison-Himmelfarb CR,Agyemang C

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:The main objective was to examine the role of hemodynamics in rat aortic and left ventricular hypertrophy produced by sinoaortic denervation (SAD). DESIGN AND METHODS:Rats were examined at different times after SAD or sham operation (Sham). Hemodynamics were recorded continuously in conscious unrestrained ra...

journal_title：Journal of hypertension

authors： Miao CY,Su DF

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:Arterial stiffness is an independent cardiovascular risk factor. Aging, high blood pressure and increased renin-angiotensin system activity contribute to increased arterial stiffness in patients with atherosclerotic renovascular hypertension (aRVH). A literature search failed to identify any study related to ...

journal_title：Journal of hypertension

authors： Fodor L,Premužić V,Ivković V,Perkov D,Laganović M,Vrkić TZ,Dika Z,Zivko M,Jelaković B

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:Guidelines recommend lower threshold and goal blood pressure (BP) for patients with proteinuria. BP reduction could be accompanied by a different fall in proteinuria depending of the antihypertensive drug. The objective was to compare proteinuria reduction when BP is lowered to the same level with different d...

journal_title：Journal of hypertension

authors： PROCOPA Study Group.

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To assess the diagnostic accuracy of recommendations for self-monitoring blood pressure (BP) for diagnosing hypertension in primary care. METHODS:Two hundred and forty-seven consecutive participants with raised (≥130 mmHg systolic) BP measured by their general practitioner from four primary care practices in...

journal_title：Journal of hypertension

authors： Nunan D,Thompson M,Heneghan CJ,Perera R,McManus RJ,Ward A

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that vascular beta 2-adrenoceptor hyporesponsiveness in spontaneously hypertensive rats (SHR) is not induced by increased blood pressure or venous hypertrophy. DESIGN:We compared the attenuating effects or isoprenaline, sodium nitroprusside and verapamilon the portal veins from Wistar-...

journal_title：Journal of hypertension

authors： Doggrell SA,Surman AJ

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:Studies of experimental animals show glomerular hypertension to be important in the progression of glomerular disease. We evaluated this connection clinically by examining the relationship between glomerular hemodynamics and histological changes in patients with immunoglobulin (Ig)A nephropathy. METHODS:The ...

journal_title：Journal of hypertension

authors： Konishi Y,Imanishi M,Okamura M,Yoshioka K,Okumura M,Okada N,Tanaka S,Fujii S,Kimura G

更新日期：2000-01-01 00:00:00

abstract：:Many physiological variables known or thought to affect erythrocyte Na+,K+-cotransport are altered in pregnancy. The interrelationships of Na+,K+-cotransport and pregnancy were therefore examined. Values were elevated by more than 30% in both second and third trimesters with a return towards non-pregnant levels in the...

journal_title：Journal of hypertension

authors： Gallery ED,Esber RP,Brown MA,Hawkins MR,Ross M

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVES:Enhanced central sympathetic outflow is an indicator of the prognosis of heart failure. Although the central sympatholytic drug moxonidine is an established therapeutic strategy for hypertension, its benefits for hypertensive heart failure are poorly understood. In the present study, we investigated the effe...

journal_title：Journal of hypertension

authors： Honda N,Hirooka Y,Ito K,Matsukawa R,Shinohara K,Kishi T,Yasukawa K,Utsumi H,Sunagawa K

更新日期：2013-11-01 00:00:00

abstract：AIM:Since canine hereditary essential hypertension has been previously reported in a colony of Siberian husky dogs, we tested the suitability of this model for use in studies on the platelet defect identified in humans with essential hypertension. METHODS:Platelet aggregation and dense granule ATP secretion were measu...

journal_title：Journal of hypertension

authors： Thomas JS,McConnell MF,Bell TG,Padgett GA

更新日期：1992-12-01 00:00:00

abstract：OBJECTIVES:To evaluate the clinic and ambulatory blood pressure (BP)-lowering efficacy and safety of an aliskiren/amlodipine/hydrochlorothiazide (HCT) triple combination compared with the component dual combinations, in patients with moderate-to-severe hypertension. METHODS:This 8-week, double-blind, randomized, activ...

journal_title：Journal of hypertension

authors： Lacourcière Y,Taddei S,Konis G,Fang H,Severin T,Zhang J

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:This study analyzed regional differences in blood pressure (BP) distribution and management in Germany 2008-2011 in a nationwide study. METHODS:The analyses were based on standardized BP measurements and anatomical therapeutic chemical classification-coded medication from the population-based German Health I...

journal_title：Journal of hypertension

authors： Diederichs C,Neuhauser H

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Cardiovascular risk prediction is deemed fundamental and the assessment of organ damage is emerging as a potentially 'downstream' picture of individual risk. Our aim was to assess the feasibility and value of prediction of coronaropathy [coronary artery disease (CAD)] of integrated cardiovascular ultrasound e...

journal_title：Journal of hypertension

authors： Moreo A,Gaibazzi N,Faggiano P,Mohammed M,Carerj S,Mureddu G,Pigazzani F,Muiesan L,Salvetti M,Cesana F,Faden G,Facchetti R,Giannattasio C,Rigo F

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to estimate the prevalence and risk factors of prehypertension (Pre-HTN) and hypertension (HTN) among the adult population of Iran. METHODS:A nationwide cross-sectional survey was conducted from December 2004 to February 2005. The selection was conducted by stratified probability cl...

journal_title：Journal of hypertension

authors： Janghorbani M,Amini M,Gouya MM,Delavari A,Alikhani S,Mahdavi A

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To evaluate autonomic nervous function by power-spectral analysis of heart-rate variability in salt-sensitive and non-salt-sensitive patients with essential hypertension under the conditions of low and high salt intakes. DESIGN AND METHODS:The blood pressures, heart rates, and electrocardiogram R-R intervals...

journal_title：Journal of hypertension

authors： Minami J,Kawano Y,Ishimitsu T,Takishita S

更新日期：1997-07-01 00:00:00

abstract：:To elucidate whether a difference exists in blood pressure (BP) elevation during isometric handgrip exercise (IHG) between essential hypertensives (EHT) and normotensives (NT), IHG was carried out in 12 NT and 46 EHT under constant sodium intake using a new instrument. The acute effects of propranolol and prazosin on ...

journal_title：Journal of hypertension

authors： Hamada M,Kazatani Y,Shigematsu Y,Ito T,Kokubu T,Ishise S

更新日期：1987-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the consistency between a randomly recruited Western European population and the participants of the Framingham Heart Study, with respect to the rates and determinants of progression to hypertension. METHODS:Among the non-hypertensive individuals enrolled in the Flemish Study on Environment, Gene...

journal_title：Journal of hypertension

authors： Zhang H,Thijs L,Kuznetsova T,Fagard RH,Li X,Staessen JA

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:Hypertension and fractures related to osteoporosis are major public health problems that often coexist. This study examined the associations between exposure to different antihypertensive drug classes and the risk of hip fracture in hypertensive patients. METHOD:We included 59 246 individuals, 50 years and o...

journal_title：Journal of hypertension

authors： Bokrantz T,Schiöler L,Boström KB,Kahan T,Mellström D,Ljungman C,Hjerpe P,Hasselström J,Manhem K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence and associated risks of white-coat hypertension (WCH) are still a matter of debate. We aimed to assess differences in prevalence and associated conditions of WCH defined on the basis of the normality of all daytime, night-time, and 24-h blood pressure (BP), only daytime, or only 24-h B...

journal_title：Journal of hypertension

authors： de la Sierra A,Vinyoles E,Banegas JR,Segura J,Gorostidi M,de la Cruz JJ,Ruilope LM

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Transport activities of cardiac sodium-calcium exchange and sarcoplasmic reticulum calcium ATPase were measured biochemically in spontaneously hypertensive rats (SHR) with hypertrophied myocardium and in normotensive Wistar-Kyoto (WKY) rats and it was tested whether possible differences have consequences for ...

journal_title：Journal of hypertension

authors： Lammerich A,Günther J,Pfitzer G,Storch E,Vetter R

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVES:Lower parental education is associated with higher adolescent blood pressure (BP). We examined the contribution of modifiable risk factors from infancy to adolescence that could potentially explain the link between parental education and SBP and DBP in the offspring. METHODS:In a prospective Chinese birth c...

journal_title：Journal of hypertension

authors： Kwok MK,Schooling CM,Subramanian SV,Leung GM,Kawachi I

更新日期：2016-09-01 00:00:00

abstract：:The effects of i.v. injection of intact digoxin antibody (0.3 mg/rat) and of its Fab fragment (40 mg/rat) on blood pressure, cardiac output and total peripheral resistance were measured in conscious spontaneously hypertensive and deoxycorticosterone hypertensive rats. In vitro findings showed that Fab fragment bound r...

journal_title：Journal of hypertension

authors： Mann JF,Miemietz R,Ganten U,Ritz E

更新日期：1987-10-01 00:00:00

abstract：:Adequate evaluation of automated sphygmomanometers, in terms of safety, accuracy, mechanical reliability, patient acceptability and ability to record ambulatory blood pressure is essential before these devices are used in clinical practice and in clinical trials. We have evaluated the accuracy and performance of the A...

journal_title：Journal of hypertension

authors： Jamieson MJ,Fowler G,MacDonald TM,Webster J,Witte K,Lawson L,Crichton W,Jeffers TA,Petrie JC

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:Molecular variants of the angiotensinogen (AGT) and the angiotensin II type 1 receptor (ATR) genes have been associated with the risk of coronary artery disease (CAD) and myocardial infarction (MI), but data so far available are conflicting. The primary object of the paper is to verify this possible associati...

journal_title：Journal of hypertension

authors： Olivieri O,Stranieri C,Girelli D,Pizzolo F,Grazioli S,Russo C,Pignatti PF,Corrocher R

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Few data are available comparing the effects of monotherapy and combination therapy on target organ damage. The PICXEL study compared the efficacy of a strategy based on first-line combination with perindopril/indapamide versus monotherapy with enalapril in reducing left ventricular hypertrophy (LVH) in hyper...

journal_title：Journal of hypertension

authors： Dahlöf B,Gosse P,Guéret P,Dubourg O,de Simone G,Schmieder R,Karpov Y,García-Puig J,Matos L,De Leeuw PW,Degaute JP,Magometschnigg D,PICXEL Investigators.

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVE:Optimal medication use obscures the impact of physical activity on traditional cardiometabolic risk factors. We evaluated the relationship between step counts and carotid-femoral pulse wave velocity (cfPWV), a summative risk indicator, in patients with type 2 diabetes and/or hypertension. RESEARCH DESIGN AND...

journal_title：Journal of hypertension

authors： Dasgupta K,Rosenberg E,Joseph L,Trudeau L,Garfield N,Chan D,Sherman M,Rabasa-Lhoret R,Daskalopoulou SS

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To examine in a population with a high prevalence of hypertension, the association between six cardiovascular polymorphisms, arterial stiffness and medication use. METHODS:In this cross-sectional study (Hypertension: Interaction and Prevalence of POlymorphisms related to Cardiovascular Risk and the Associati...

journal_title：Journal of hypertension

authors： Plat AW,Stoffers HE,de Leeuw PW,van Schayck CP,Soomers FL,Kester AD,Aretz K,Kroon AA

更新日期：2009-01-01 00:00:00

abstract：:Systolic blood pressure was measured on a total of 1855 occasions in 1307 children aged four and five years, and compared with values obtained since birth in the same children. There was a rapid rise in blood pressure in the first month of life. The mean blood pressure then only rose from 93 mmHg at six months to 98 m...

journal_title：Journal of hypertension

authors： de Swiet M,Fayers PM,Shinebourne EA

更新日期：1984-10-01 00:00:00