Abstract:
:Botulinum toxin A (BTX-A) is increasingly being used in early management of spasticity in ambulant children with cerebral palsy (CP), with the aim of improving function, promoting muscle growth, and delaying the need for surgical intervention. However, there is a lack of evidence about the long-term outcome of BTX-A injections. The focus on spasticity as the predominant problem in younger children with spastic CP may not fully consider the associated muscle weakness. It also raises concern that although BTX-A may improve function in the short term, it has the potential to affect muscle growth and function adversely in the long term. A cautious approach to the early use of BTX-A, with the use of objective outcome measures within a specialized multidisciplinary setting, is recommended, particularly in ambulant children with spastic diplegic CP, until further evidence is available on the long-term outcome of early BTX-A injections in children with CP.
journal_name
Dev Med Child Neuroljournal_title
Developmental medicine and child neurologyauthors
Gough M,Fairhurst C,Shortland APdoi
10.1017/S0012162205001453subject
Has Abstractpub_date
2005-10-01 00:00:00pages
709-12issue
10eissn
0012-1622issn
1469-8749pii
S0012162205001453journal_volume
47pub_type
杂志文章,评审abstract::Neural reuse is the process by which neural elements originally developed for one purpose are put to many different subsequent uses. In this brief review I will outline the role of neural reuse in the development of the brain. Special attention will be paid to elucidating and differentiating between two different mech...
journal_title:Developmental medicine and child neurology
pub_type: 杂志文章,评审
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journal_title:Developmental medicine and child neurology
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更新日期:1996-05-01 00:00:00
abstract:AIM:To investigate the underlying factor structure of the 46-item Flemish cerebral visual impairment (CVI) questionnaire, differentiate the factor scores of children with and without CVI, and examine the impact of comorbidities on factor scores. METHOD:The records of 630 children (386 males, 244 females; median age 77...
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章
doi:10.1111/j.1469-8749.1989.tb04072.x
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章,评审
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章
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更新日期:1984-04-01 00:00:00
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journal_title:Developmental medicine and child neurology
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doi:10.1017/s0012162204000635
更新日期:2004-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:1984-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1469-8749.1990.tb08105.x
更新日期:1990-10-01 00:00:00
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更新日期:2015-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2011-03-01 00:00:00
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章
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更新日期:1990-07-01 00:00:00
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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journal_title:Developmental medicine and child neurology
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journal_title:Developmental medicine and child neurology
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pub_type: 杂志文章
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更新日期:2004-10-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章
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更新日期:1986-10-01 00:00:00
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journal_title:Developmental medicine and child neurology
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:1988-04-01 00:00:00