Acute dystonic reaction to bethanechol--a direct acetylcholine receptor agonist.

Abstract:

:Bethanechol is a direct agonist of the acetylcholine receptor that was recently introduced in the therapy of gastro-oesophageal reflux. Acute dystonic reactions to bethanechol were observed in a 10-month-old infant who also demonstrated similar dystonic reactions to dopamine receptor blocking agents of two different classes. This first report of acute dystonic reaction to cholinergic agonists in human is in accord with the current theories of the rôle of acetylcholine and dopamine in the pathogenesis of acute dystonic reactions.

journal_name

Dev Med Child Neurol

authors

Shafrir Y,Levy Y,Beharab A,Nitzam M,Steinherz R

doi

10.1111/j.1469-8749.1986.tb03909.x

subject

Has Abstract

pub_date

1986-10-01 00:00:00

pages

646-8

issue

5

eissn

0012-1622

issn

1469-8749

journal_volume

28

pub_type

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