Abstract：
:In a multicenter study, the overall correlation between two variables can be broken down into a within- and a between-group correlation reflecting associations at the individual and aggregate levels, respectively. A random-effects model is used to estimate variance components of nutrition-related variables and the within- and between-group correlation coefficients. Using data from the European Prospective Investigation into Cancer and Nutrition (EPIC), the authors analyzed the association between levels of three plasma carotenoids (alpha-carotene, beta-cryptoxanthin, and lycopene) and dietary intake of three items (total fruits, carrots, and tomatoes), assessed through dietary questionnaire and single 24-hour dietary recall measurements, in a cross-sectional study involving 3,089 subjects from nine European countries. Intraclass correlation coefficients were 0.178 for alpha-carotene, 0.216 for beta-cryptoxanthin, and 0.299 for lycopene. The between-group correlation coefficients were higher than the within-group coefficients for all three carotenoids. For beta-cryptoxanthin and fruit intake, the between-group versus the within-group correlations were 0.78 and 0.26 for the dietary questionnaire and 0.85 and 0.19 for the 24-hour dietary recall. Results indicate that variability of exposure is driven mainly by the individual compared with the aggregate variation and that biomarker levels perform fairly accurately in discriminating population-level consumption of fruits and vegetables.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Ferrari P,Al-Delaimy WK,Slimani N,Boshuizen HC,Roddam A,Orfanos P,Skeie G,Rodríguez-Barranco M,Thiebaut A,Johansson G,Palli D,Boeing H,Overvad K,Riboli Edoi
10.1093/aje/kwi242subject
Has Abstractpub_date
2005-09-15 00:00:00pages
591-8issue
6eissn
0002-9262issn
1476-6256pii
kwi242journal_volume
162pub_type
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