Modeling and simulations of the pharmacokinetics of fluorophore conjugated antibodies in tumor vicinity for the optimization of fluorescence-based optical imaging.

abstract：BACKGROUND AND OBJECTIVE:Alternative treatments are needed to achieve consistent and more complete port wine stain (PWS) removal, especially in darker skin types; photodynamic therapy (PDT) is a promising alternative treatment. To this end, we previously reported on Talaporfin Sodium (TS)-mediated PDT. It is essential ...

journal_title：Lasers in surgery and medicine

authors： Moy WJ,Yao J,de Feraudy SM,White SM,Salvador J,Kelly KM,Choi B

更新日期：2017-10-01 00:00:00

abstract：:Progress in the young field of laser recanalization of occluded arteries and applications in cardiovascular disease to which many investigators have contributed is briefly summarized. Specific problems remaining to be solved are set forth. In conclusion, the author makes a cautious prediction of success for the percut...

journal_title：Lasers in surgery and medicine

authors： Choy DS

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We reported the use of Holmium-YAG laser in the management of a foreign body impacted in the esophagus. STUDY DESIGN/PATIENTS AND METHODS:Esophagoscopy was performed on a man with a denture impacted in the esophagus. The denture was disimpacted into the stomach and fractured with Holmium-YAG l...

journal_title：Lasers in surgery and medicine

authors： Lam YH,Ng EK,Chung SC,Li AK

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Laser-induced photo thermal damage has been combined with photodynamic therapy (PDT) using a systemic photosensitiser to treat vascular lesions. The efficacy of PDT using systemic 5-aminolaevulinic acid (5-ALA) as the photosensitiser and pulsed dye laser (PDL) as the light source in port wine ...

journal_title：Lasers in surgery and medicine

authors： Evans AV,Robson A,Barlow RJ,Kurwa HA

更新日期：2005-04-01 00:00:00

abstract：:The time constant model, as an approximation to the bio-heat equation, was tested for non-ablating, deep penetrating (argon) laser beams in absorbing tissue phantoms (polyacrylamide) in air. Temperature responses were measured with a thermal camera, both during laser irradiation as well as after the laser beam was swi...

journal_title：Lasers in surgery and medicine

authors： Meijering LJ,van Gemert MJ,Gijsbers GH,Welch AJ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The risk of adverse skin effects following light-based hair removal is greater in pigmented skin based on the theory of selective photothermolysis. Thus sunlight-induced pigment i.e., facultative pigmentation, increases the risk of adverse skin effects, perhaps disproportionately. The aim of t...

journal_title：Lasers in surgery and medicine

authors： Thaysen-Petersen D,Lin JY,Nash J,Beerwerth F,Wulf HC,Philipsen PA,Haedersdal M

更新日期：2014-02-01 00:00:00

abstract：:Our experiments on transmitting high-power excimer laser pulses through optical fibers and our investigations on excimer laser ablation of hard tissue show the feasibility of using the excimer laser as an additional instrument in general and accident surgery involving minimal invasive surgery. By combining XeCl-excime...

journal_title：Lasers in surgery and medicine

authors： Dressel M,Jahn R,Neu W,Jungbluth KH

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The pulsed holmium laser is a promising tool for tissue ablation but possesses some limitations. For example, it is capable of producing significant mechanical damage in certain tissues in the form of fissures and fractures. Because longer pulse durations should reduce mechanical damage, this s...

journal_title：Lasers in surgery and medicine

authors： Domankevitz Y,McMillan K,Nishioka NS

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Pulsed dye laser (PDL) is the first choice for treatment of port wine stains (PWS). However, outcome is highly variable and only a few patients achieve complete clearance. The objective of the study was to compare efficacy and safety of single pass PDL with double pass PDL at a 6 minute interval. METHODS:We...

journal_title：Lasers in surgery and medicine

authors： Peters MA,van Drooge AM,Wolkerstorfer A,van Gemert MJ,van der Veen JP,Bos JD,Beek JF

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Inhibition of cyclooxygenase (COX) and prostaglandin E(2) (PGE(2)) protects cells against cell injury in specific pathophysiological situations: inflammation and oxidative stress. Although the anti-inflammatory effects have been reported in clinical fields for specific wavelength irradiation d...

journal_title：Lasers in surgery and medicine

authors： Lim W,Lee S,Kim I,Chung M,Kim M,Lim H,Park J,Kim O,Choi H

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To investigate the morphology of cementum and root dentin after Er:YAG laser irradiation with and without water coolant, compared to that after CO(2) laser irradiation and an untreated surface. STUDY DESIGN/MATERIALS AND METHODS:Ten extracted healthy human teeth were used. Er:YAG and CO(2) la...

journal_title：Lasers in surgery and medicine

authors： Sasaki KM,Aoki A,Ichinose S,Ishikawa I

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Endoscopic examination followed by tissue biopsy is the gold standard in the evaluation of lesions of the upper aerodigestive tract. However, it can be difficult to distinguish between healthy mucosa, dysplasia, and invasive carcinoma. Optical coherence tomography (OCT) is a non-invasive technique which acqui...

journal_title：Lasers in surgery and medicine

authors： Englhard AS,Betz T,Volgger V,Lankenau E,Ledderose GJ,Stepp H,Homann C,Betz CS

更新日期：2017-07-01 00:00:00

abstract：:Percutaneous endoscopic approaches to cholelithiasis would be facilitated by methods for welding gallbladder tissues. We evaluated the bursting pressure and histologic appearance of canine gallbladder tissue welded with a thulium-holmium-chromium:YAG (THC:YAG) laser producing a 2.15 microns pulsed output. The tissue a...

journal_title：Lasers in surgery and medicine

authors： Popp HW,Oz MC,Bass LS,Chuck RS,Trokel SL,Treat MR

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Lasers are used for caries removal in enamel and dentin, but are currently limited in their ability to remove sound tooth structure. In this study plasma interaction regimes are investigated as the principal factor determining the ablation characteristics. STUDY DESIGN/MATERIALS AND METHODS:Th...

journal_title：Lasers in surgery and medicine

authors： Neev J,Pham K,Lee JP,White JM

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Moraxella catarrhalis is a significant cause of pediatric otitis media (OM), which is the most prevalent bacterial infection in children and primary reason for antibiotic administration in this population. Moreover, biofilm formation has been implicated as a primary mechanism of chronic or recu...

journal_title：Lasers in surgery and medicine

authors： Luke-Marshall NR,Mang TS,Hansen LA,Campagnari AA

更新日期：2014-11-01 00:00:00

abstract：:We hypothesized that autologous clot deposited on the luminal surface of laser vascular welds immediately after creation would produce higher time zero bursting pressures that could be achieved in welds perfused with saline alone. To test this hypothesis, we compared bursting pressures of welds created in isolated rab...

journal_title：Lasers in surgery and medicine

authors： Oz MC,Bass LS,Chuck RS,Johnson JP,Parangi S,Nowygrod R,Treat MR

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This laboratory animal study is a comparison of Nd:YAG 1064 nm and diode 810 nm laser wavelengths in brain interstitial laser photocoagulation (ILP). Specific goals were to identify potential complications and physical characteristics of the thermal damage at both wavelengths prior to undertaki...

journal_title：Lasers in surgery and medicine

authors： Wyman DR,Schatz SW,Maguire JA

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Most women with early stage breast cancer have the option of breast conserving therapy, which involves a partial mastectomy for removal of the primary tumor, usually followed by radiotherapy. The presence of tumor at or near the margin is strongly correlated with the risk of local tumor recurre...

journal_title：Lasers in surgery and medicine

authors： Keller MD,Majumder SK,Kelley MC,Meszoely IM,Boulos FI,Olivares GM,Mahadevan-Jansen A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Various yellow light lasers have been used over the past decade in an attempt to eradicate facial telangiectasia. Based on their power output, spot size, and pulsing characteristics, these lasers belong to one of two categories that exist at either end of a spectrum--high power, short pulse, an...

journal_title：Lasers in surgery and medicine

authors： McCoy SE

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Infrared neural stimulation (INS) has recently evoked interest as an alternative to electrical stimulation. The mechanism of activation is the heating of water, which induces changes in cell membrane potential but may also trigger heat sensitive receptors. To further elucidate the mechanism, wh...

journal_title：Lasers in surgery and medicine

authors： Liljemalm R,Nyberg T,von Holst H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To evaluate the antiallergic effect of low-level laser irradiation (LLLI) at 650 nm in a mouse model of allergic rhinitis (AR), and to examine the underlying mechanisms. STUDY DESIGN/MATERIALS AND METHODS:BALB/c mice were sensitized with ovalbumin (OVA) and alum and challenged intranasally wi...

journal_title：Lasers in surgery and medicine

authors： Bae JS,Kim SH,Kim JH,Kim EH,Lyu L,Chung PS,Mo JH

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Facial teleangectasias can be a relevant cosmetic problem, which the patient usually hides with a thick layer of makeup. This study will describe the response on these vascular lesions using the intense pulsed light (IPL) source. METHODS:Five hundred eighteen consecutive patients were treated...

journal_title：Lasers in surgery and medicine

authors： Clementoni MT,Gilardino P,Muti GF,Signorini M,Pistorale A,Morselli PG,Cavina C

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:LED photomodulation has been shown to profoundly influence cellular behavior. A variety of parameters with LED photomodulation can alter cellular response in vitro. The effects of one visible and one infrared wavelength were evaluated to determine the optimal ratio to produce a net increase in ...

journal_title：Lasers in surgery and medicine

authors： McDaniel DH,Weiss RA,Geronemus RG,Mazur C,Wilson S,Weiss MA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cutaneous and mucocutaneous leishmaniasis are diseases characterized by skin or mucosal manifestations. In the new world, Leishmania braziliensis is the main etiological agent of cutaneous leishmaniasis, condition that may evolve to the mucocutaneous form. The therapeutic arsenal routinely empl...

journal_title：Lasers in surgery and medicine

authors： Barbosa AF,Sangiorgi BB,Galdino SL,Barral-Netto M,Pitta IR,Pinheiro AL

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:5-Aminolevulinic acid based photodynamic therapy (5-ALA-PDT) has revealed promising results in the treatment of inflammatory joint diseases due to the sensitivity of inflamed synovial tissue. For 5-ALA-PDT to be safe and beneficial for intra-articular applications, resistance of chondrocytes is essential to p...

journal_title：Lasers in surgery and medicine

authors： Egli RJ,Di Criscio A,Hempfing A,Schoeniger R,Ganz R,Hofstetter W,Leunig M

更新日期：2008-04-01 00:00:00

abstract：:One carotid from each dog underwent a laser anastomosis and the other carotid an interrupted suture repair. One or eight weeks later (n greater than or equal to 4 dogs/time period); four rings (1 mm in length) containing the laser or suture anastomosis or the normal artery (two/dog) were removed. Using a photoelectric...

journal_title：Lasers in surgery and medicine

authors： Dalsing MC,Packer CS,Kueppers P,Griffith SL,Davis TE

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Pores in the sclera are a candidate pathway for aqueous transport and therefore can be utilized to decrease the intraocular pressure (IOP) in glaucomatous eyes. Since pore formation is a well-known mechanism for stress relaxation in solids, laser-induced creation of pores in cartilage increase...

journal_title：Lasers in surgery and medicine

authors： Baum OI,Sobol EN,Bolshunov AV,Fedorov AA,Khomchik OV,Omelchenko AI,Shcherbakov EM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) using topical aminolevulinic acid (ALA) depends on local drug uptake, metabolism to porphyrins, and depth of light penetration using different wavelengths. Topical ALA-PDT has limited depth of drug penetration. We studied induced porphyrin distribution and PDT after intradermal ALA...

journal_title：Lasers in surgery and medicine

authors： Sakamoto FH,Doukas AG,Farinelli WA,Tannous Z,Su Y,Smith NA,Zurakowski D,Anderson RR

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:Intravascular photoacoustic (IVPA) imaging is being developed to image atherosclerotic plaques, a leading cause of morbidity and mortality in the United States. However, the safety of this imaging modality, which requires repeated irradiation with short laser pulses, has not yet been investigated. This study...

journal_title：Lasers in surgery and medicine

authors： Sowers T,VanderLaan D,Karpiouk A,Donnelly EM,Smith E,Emelianov S

更新日期：2018-10-10 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Herein an overview is provided of the causes, consequences, and significance of photodynamic therapy (PDT)-mediated effects on tumor oxygenation and blood flow during illumination. STUDY DESIGN/MATERIALS AND METHODS:Techniques particularly valuable to this research have included tissue oxygen ...

journal_title：Lasers in surgery and medicine

authors： Busch TM

更新日期：2006-06-01 00:00:00