Selection of controls in case-control studies. III. Design options.

Abstract:

:Several design options available in the planning stage of case-control studies are examined. Topics covered include matching, control/case ratio, choice of nested case-control or case-cohort design, two-stage sampling, and other methods that can be used for control selection. The effect of potential problems in obtaining comparable accuracy of exposure is also examined. A discussion of the difficulty in meeting the principles of study base, deconfounding, and comparable accuracy (S. Wacholder et al. Am J Epidemiol 1992;135:1019-28) in a single study completes this series of papers.

journal_name

Am J Epidemiol

authors

Wacholder S,Silverman DT,McLaughlin JK,Mandel JS

doi

10.1093/oxfordjournals.aje.a116398

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

1042-50

issue

9

eissn

0002-9262

issn

1476-6256

journal_volume

135

pub_type

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