Abstract：
:Apoptotic cell death in animals is regulated by cysteine proteinases called caspases. Recently, vacuolar processing enzyme (VPE) was identified as a plant caspase. VPE deficiency prevents cell death during hypersensitive response and cell death of limited cell layers at the early stage of embryogenesis. Because plants do not have macrophages, dying cells must degrade their materials by themselves. VPE plays an essential role in the regulation of the lytic system of plants during the processes of defense and development. VPE is localized in the vacuoles, unlike animal caspases, which are localized in the cytosol. Thus, plants might have evolved a regulated cellular suicide strategy that, unlike animal apoptosis, is mediated by VPE and the vacuoles.
journal_name
Curr Opin Plant Bioljournal_title
Current opinion in plant biologyauthors
Hara-Nishimura I,Hatsugai N,Nakaune S,Kuroyanagi M,Nishimura Mdoi
10.1016/j.pbi.2005.05.016subject
Has Abstractpub_date
2005-08-01 00:00:00pages
404-8issue
4eissn
1369-5266issn
1879-0356pii
S1369-5266(05)00077-4journal_volume
8pub_type
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