当前位置： SCI文献检索 > PSYCHIATRY AND CLINICAL NEUROSCIENCES期刊下所有文献 > Behavioral and psychological symptoms of dementia characteristic of mild Alzheimer patients.

Behavioral and psychological symptoms of dementia characteristic of mild Alzheimer patients.

Abstract：

:In order to clarify the characteristics of Behavioral and Psychological Symptoms of Dementia (BPSD) in patients with mild Alzheimer's disease (AD), BPSD among the severities of Clinical Dementia Rating (CDR) in 74 patients with AD were compared using the Neuropsychiatric inventory (NPI). The result, when compared between mild (CDR = 0.5, 1) and moderate or severe (CDR = 2, 3) AD, was a significant difference in frequency of euphoria, disinhibition and aberrant motor behavior, but no significant difference was found in frequency of delusions, hallucinations, agitation, dysphoria, anxiety, apathy and irritability. In addition, a significant difference was found in the mean scores of the composite score for euphoria, apathy, disinhibition and aberrant motor behavior, but no significant difference was found in the mean scores of the composite score for delusions, hallucinations, agitation, dysphoria, anxiety and irritability. That is, the mild AD groups (CDR 0.5 or 1) had delusions, hallucinations, agitation, dysphoria, anxiety, apathy and irritability as frequently as the moderate or severe AD groups (CDR 2 or 3), and had the equivalent level of composite scores to the moderate or severe AD groups (CDR 2 or 3) in delusion, hallucination, agitation, dysphoria, anxiety and irritability. Therefore, it was supposed that psychotic symptoms (delusion, hallucination) and emotional symptoms (agitation, dysphoria, anxiety, irritability) are important BPSD in patients with mild AD as well as those with moderate or severe AD, and there are needs for health, welfare and medical services for these symptoms.

journal_name

Psychiatry Clin Neurosci

journal_title

Psychiatry and clinical neurosciences

authors

Shimabukuro J,Awata S,Matsuoka H

doi

10.1111/j.1440-1819.2005.01371.x

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

274-9

issue

3

eissn

1323-1316

issn

1440-1819

pii

PCN1371

journal_volume

59

pub_type

临床试验,杂志文章

相关文献

PSYCHIATRY AND CLINICAL NEUROSCIENCES文献大全
  • Usefulness of near-infrared spectroscopy to detect brain dysfunction in children with autism spectrum disorder when inferring the mental state of others.

    abstract：AIMS:The purpose of this study was to examine the usefulness of near-infrared spectroscopy (NIRS) for identifying abnormalities in prefrontal brain activity in children with autism spectrum disorders (ASD) as they inferred the mental states of others. METHODS:The subjects were 16 children with ASD aged between 8 and 1...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/pcn.12052

    authors： Iwanaga R,Tanaka G,Nakane H,Honda S,Imamura A,Ozawa H

    更新日期：2013-05-01 00:00:00

  • Effect of age and gender on schizotypal personality traits in the normal population.

    abstract：AIM:There is some evidence that age and gender influence expression of schizotypal traits in the normal population. One important limitation of previous studies, however, is the restricted age range of subjects. The aim of the present study was therefore to investigate the effect of gender and age on schizotypal person...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2009.02011.x

    authors： Bora E,Baysan Arabaci L

    更新日期：2009-10-01 00:00:00

  • Prefrontal GABA and glutamate levels correlate with impulsivity and cognitive function of prescription opioid addicts: A 1 H-magnetic resonance spectroscopy study.

    abstract：AIM:Prescription opioids are psychoactive substances that can elicit many neuropsychological effects. There are no studies that directly demonstrate the effects of prescription opioid addiction (POA) on the human brain. This study aimed to quantify γ-aminobutyric acid (GABA) and glutamate (Glu) levels in the prefrontal...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/pcn.12940

    authors： Li JN,Liu XL,Li L

    更新日期：2020-01-01 00:00:00

  • Plasma nitrate values in patients with obsessive-compulsive disorder.

    abstract：:Recently there has been increasing evidence that free oxygen species may play an important role in the pathophysiology of various neuropsychiatric disorders. The present study was performed to assess the changes in plasma nitric oxide (NO) levels in patients with obsessive-compulsive disorder (OCD) compared to age- an...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2005.01426.x

    authors： Atmaca M,Tezcan E,Kuloglu M,Ustundag B

    更新日期：2005-10-01 00:00:00

  • Attentional dysfunction of chronic schizophrenia: No association with long-term institutionalization.

    abstract：:Attentional processes play a central role in information selection, which is impaired in schizophrenic patients. In the present study, we attempted to characterize the attentional performance of chronic schizophrenics using a computerized assessment of the multiple components of attentional function. Two comparable sa...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1046/j.1440-1819.2002.01031.x

    authors： Cremasco L,Cappa SF

    更新日期：2002-08-01 00:00:00

  • Social support and pregnancy: I. Factorial structure and psychosocial correlates of perceived social support.

    abstract：:In a questionnaire survey among 1329 first-trimester pregnant women, social support providers were divided by factor analysis into husband, 'premarital network' (parents and friends) and 'postmarital network' (children and mother-in-law), while social support contents were divided into 'given' (emotional, informationa...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.1998.tb00969.x

    authors： Kitamura T,Toda MA,Shima S,Sugawara K,Sugawara M

    更新日期：1998-02-01 00:00:00

  • Spinal tract degeneration confined to the bilateral posterior columns in malnutrition: report of an autopsy.

    abstract：:An autopsy case of malnutrition with spinal tract degeneration confined to the bilateral posterior columns is reported. The patient had schizophrenia in adolescence, and suffered from aplastic anemia in late middle age. Subsequently, he took little food due to delusions for 18 months until his death. He had malnutriti...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.1995.tb01862.x

    authors： Fukutani Y,Katsukawa K,Ishizaki K,Takeshima T,Kobayashi K,Yamaguchi N,Nakamura I,Watanabe K

    更新日期：1995-03-01 00:00:00

  • A longitudinal study of diurnal variation in baseline fetal heart rate in one dichorionic-diamniotic twin pregnancy.

    abstract：:A longitudinal study to analyse the diurnal variations in baseline fetal heart rate (FHR) and sustained fetal tachycardia (SFT) in twin pregnancy was performed on one dichorionic twin. Twenty-four hour FHR recordings on twins were made at 32, 34 and 36 weeks of gestation simultaneously. Significant diurnal variations ...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1046/j.1440-1819.2001.00834.x

    authors： Muro M,Shono H,Shono M,Ito Y,Iwasaka T

    更新日期：2001-06-01 00:00:00

  • Tardive dystonia provoked by concomitantly administered risperidone.

    abstract：:Two cases of tardive dystonia are reported. The first case was an 18-year-old schizophrenic woman suffering from parkinsonism and hypotension induced by antipsychotic drugs. Risperidone (4 mg/day) was added to her drug regimen and after increasing the dosage to 6 mg/day, she began to exhibit retrocollis. The second ca...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1046/j.1440-1819.2000.00743.x

    authors： Tachikawa H,Suzuki T,Kawanishi Y,Hori M,Hori T,Shiraishi H

    更新日期：2000-08-01 00:00:00

  • Efficacy of open-system social skills training in inpatients with mood, neurotic and eating disorders.

    abstract：:Open-system social skills training (SST) was performed in an open psychiatric ward of the hospital of Yokohama City University. Between June 1998 and March 2000, 223 patients were being treated for various mental disorders and 136 of these patients voluntarily participated in the open-system SST at least once. The SST...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 临床试验,杂志文章

    doi：10.1046/j.1440-1819.2003.01120.x

    authors： Takahashi M,Kosaka K

    更新日期：2003-06-01 00:00:00

  • Recurrent brief episodes with psychotic features in adolescence: periodic psychosis of puberty revisited.

    abstract：:There are many reports of adolescents with periodic episodes, each followed by complete remission within 2 weeks; however, the nosology and long-term prognosis of such cases have not been elucidated. A prospective follow-up study on 11 cases (nine girls and two boys) who met predetermined criteria is reported. The fir...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.1998.tb03255.x

    authors： Abe K,Ohta M

    更新日期：1998-12-01 00:00:00

  • Pharmacokinetics and efficacy of a direct switch from conventional depot to risperidone long-acting injection in Chinese patients with schizophrenic and schizoaffective disorders.

    abstract：AIMS:This 12-week open-label study was designed to investigate the pharmacokinetics and efficacy of a direct switch from a conventional depot to long-acting injectable risperidone in patients with schizophrenia and schizoaffective disorder. METHODS:Men or women from 18 to 65 years old with a diagnosis of schizophrenia...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2009.01977.x

    authors： Lai YC,Huang MC,Chen CH,Tsai CJ,Pan CH,Chiu CC

    更新日期：2009-08-01 00:00:00

  • A case of insufficient sleep syndrome.

    abstract：:All night polysomnographic evaluation (PSG) soon after admission and at the late period of admission revealed an atypically high sleep efficiency and a prolonged total sleep time. Sleep onset latency and distribution of REM and NREM sleep stages were like those of normal sleepers. On REM latency, while it was remarkab...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.1998.tb01029.x

    authors： Yoshikawa N,Suzuki S,Ishimoto T,Matsumoto M,Miyagishi T

    更新日期：1998-04-01 00:00:00

  • Dissociation and alexithymia among men with alcoholism.

    abstract：AIM:The aim of the present study was to evaluate the relationship between alexithymia and dissociation among men with alcoholism. METHODS:Participants were 176 patients consecutively admitted to the inpatient unit of a addiction treatment center. The Toronto Alexithymia Scale, the Symptom Checklist-Revised, the Dissoc...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2007.01775.x

    authors： Evren C,Sar V,Evren B,Semiz U,Dalbudak E,Cakmak D

    更新日期：2008-02-01 00:00:00

  • Perception metamorphosis phenomenon in autism.

    abstract：:It is well known that various perceptual abnormalities exist in autism. However, because perceptual phenomena are intersubjective, a phenomenological approach is required for getting hold of the reality of the modes of perception involved in autism. From this standpoint, the author has proposed the concept of 'percept...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1046/j.1440-1819.1998.00460.x

    authors： Kobayashi R

    更新日期：1998-12-01 00:00:00

  • One-year prevalence and incidence of depression among first-year university students in Japan: a preliminary study.

    abstract：:A structured interview was used to examine the 1-year incidence and prevalence of depression among 116 first-year university students. While 24 of the subjects (20.7%) met the Diagnostic and Statistical Manual of Mental Disorders 4th ed. (DSM-IV) criteria for Major Depressive Episode (MDE), 62 (53.4%) met the Diagnost...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1046/j.1440-1819.2000.00757.x

    authors： Tomoda A,Mori K,Kimura M,Takahashi T,Kitamura T

    更新日期：2000-10-01 00:00:00

  • Increased densities of white matter neurons as a cross-disease feature of neuropsychiatric disorders.

    abstract：:While neurons of the human cerebral cortex are mainly distributed in the gray matter, the white matter (WM) also contains some excitatory and inhibitory neurons, so-called WM neurons. Studies on the cytoarchitectural alterations in the brains of patients with neuropsychiatric disorders have repeatedly reported increas...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章,评审

    doi：10.1111/pcn.12962

    authors： Kubo KI

    更新日期：2020-03-01 00:00:00

  • Automatic classification of major depression disorder using arterial spin labeling MRI perfusion measurements.

    abstract：AIM:Neuroimaging-based multivariate pattern-recognition methods have been successfully used to develop diagnostic algorithms to distinguish patients with major depressive disorder (MDD) from healthy controls (HC). We developed and evaluated the accuracy of a multivariate classification method for the differentiation of...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/pcn.12862

    authors： Ramasubbu R,Brown EC,Marcil LD,Talai AS,Forkert ND

    更新日期：2019-08-01 00:00:00

  • Pharmacokinetic interaction between tandospirone and fluvoxamine in the rat contextual conditioned fear stress model and its functional consequence: Involvement of cytochrome P450 3A4.

    abstract：AIMS:In a previous study it was demonstrated that the anxiolytic action of tandospirone, a 5-hydroxytryptamine (5-HT)(1A) receptor agonist, is facilitated by cytochrome P450 (CYP) 3A4 inhibitors, such as ketoconazole and cimetidine. It is also known that fluvoxamine, a selective serotonin re-uptake inhibitor (SSRI), in...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2008.01853.x

    authors： Nishikawa H,Inoue T,Masui T,Izumi T,Nakagawa S,Koyama T

    更新日期：2008-10-01 00:00:00

  • Resequencing and association analysis of MIR137 with schizophrenia in a Japanese population.

    abstract：:MicroRNA may play a role in the pathophysiology of schizophrenia. A recent meta-analysis of genome-wide association studies indicated a significant association between schizophrenia and a common intronic variation in MIR137HG (microRNA 137 host gene) encoding the primary microRNA-137. To explore additional risk variat...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/pcn.12047

    authors： Egawa J,Nunokawa A,Shibuya M,Watanabe Y,Kaneko N,Igeta H,Someya T

    更新日期：2013-05-01 00:00:00

  • Deterioration of intelligence in methamphetamine-induced psychosis: comparison with alcohol dependence on WAIS-III.

    abstract：AIMS:Long-term use of methamphetamine could induce psychosis, but consequences with regards to intelligence have seldom been investigated. Long-term use of alcohol could also result in intellectual deterioration. METHODS:The IQ of 34 methamphetamine-induced psychosis (MIP) patients (age, 28.7 +/- 6.1 years) and 34 alc...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2009.02035.x

    authors： Lin SK,Huang MC,Lin HC,Pan CH

    更新日期：2010-02-01 00:00:00

  • One-year rehospitalization rates of patients with first-episode bipolar mania receiving lithium or valproate and adjunctive atypical antipsychotics.

    abstract：AIM:We compared the 1-year rehospitalization rates of first-episode bipolar manic patients who were discharged while being treated with lithium or valproate in combination with an atypical antipsychotic. METHODS:We investigated the rehospitalization status of first-episode bipolar manic patients who were discharged be...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/pcn.12145

    authors： Woo YS,Bahk WM,Jung YE,Jeong JH,Lee HB,Won SH,Lee KH,Jon DI,Yoon BH,Kim MD,Min KJ

    更新日期：2014-06-01 00:00:00

  • Effect of organizational strategy on visual memory in patients with schizophrenia.

    abstract：AIMS:The aim of the present study was to examine how copy organization mediated immediate recall among patients with schizophrenia using the Rey-Osterrieth Complex Figure Test (ROCF). METHODS:The Boston Qualitative Scoring System (BQSS) was applied for qualitative and quantitative analyses of ROCF performances. Subjec...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2008.01821.x

    authors： Kim MS,Namgoong Y,Youn T

    更新日期：2008-08-01 00:00:00

  • Estimation of premorbid IQ in individuals with Alzheimer's disease using Japanese ideographic script (Kanji) compound words: Japanese version of National Adult Reading Test.

    abstract：:The National Adult Reading Test (NART) is widely used as a measure of premorbid IQ of the English-speaking patients with dementia. The purpose of the present study was to develop a Japanese version of the NART (JART), using 50 Japanese irregular words, all of which are Kanji (ideographic script) compound words. Readin...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2006.01510.x

    authors： Matsuoka K,Uno M,Kasai K,Koyama K,Kim Y

    更新日期：2006-06-01 00:00:00

  • Predictors of fluoxetine remission for hospitalized patients with major depressive disorder.

    abstract：AIM:The goal of treating major depressive disorder is to achieve remission. This prospective study aimed to identify predictors of remission in a cohort of depressive inpatients who received fluoxetine. METHODS:A total of 131 newly hospitalized patients with major depressive disorder received a fixed dose of 20 mg/day...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1440-1819.2011.02235.x

    authors： Lin CH,Lane HY,Chen CC,Juo SH,Yen CF

    更新日期：2011-08-01 00:00:00

  • Substance abuse, conduct disorder and crime: assessment in a juvenile detention house in Istanbul, Turkey.

    abstract：:The purpose of the present study was to determine the rate of substance abuse in the juvenile detention house and to determine the relationship between crime and substance abuse and conduct disorder. Two hundred and thirty cases in the biggest juvenile detention house in Istanbul, Turkey were assessed according to Dia...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1440-1819.2005.01350.x

    authors： Copur M,Turkcan A,Erdogmus M

    更新日期：2005-04-01 00:00:00

  • On the role of quantitative brain imaging in the differential diagnosis of speech disorders.

    abstract：:We present the case of a 71-year-old woman with an 11-year history of slowly progressive decline of motor speech. Normal clinical investigations including routine magnetic resonance imaging (MRI) at 7, 8 and 10 years after the onset of speech dysfunction led to the suggestion of a psychogenic disorder. Extensive clini...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1046/j.1440-1819.2002.00938.x

    authors： Tebartz van Elst LH,Juengling FD,Kassubek J,Schmidtke K,Thiel T,Ebert D,Dykierek P,Hüll M

    更新日期：2002-02-01 00:00:00

  • Alcohol use in Australia during the early days of the COVID-19 pandemic: Initial results from the COLLATE project.

    abstract：AIM:The effects of social isolation measures used to control the spread of COVID-19 are negatively impacting the mental health of many. One of the consequences of exposure to disasters/pandemics is an increase in alcohol use. The current study aimed to examine what predisposing (distal) and pandemic-related (proximal) ...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/pcn.13099

    authors： Neill E,Meyer D,Toh WL,van Rheenen TE,Phillipou A,Tan EJ,Rossell SL

    更新日期：2020-10-01 00:00:00

  • Neuropsychiatric symptoms predict change in quality of life of Alzheimer disease patients: a two-year follow-up study.

    abstract：AIM:To examine the effect of neuropsychiatric symptoms on longitudinal changes in the quality of life (QOL) of patients with Alzheimer disease (AD). METHODS:First, we investigated whether neuropsychiatric symptoms at baseline predict changes in the QOL of AD patients over time. Then we examined the associations betwee...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1111/j.1440-1819.2009.01955.x

    authors： Tatsumi H,Nakaaki S,Torii K,Shinagawa Y,Watanabe N,Murata Y,Sato J,Mimura M,Furukawa TA

    更新日期：2009-06-01 00:00:00

  • Widespread expression of Fos protein induced by acute haloperidol administration in the rat brain.

    abstract：:The effect of acute haloperidol administration on Fos protein expression was examined immunohistochemically in discrete regions of the rat brain. Male Wistar rats were injected subcutaneously (s.c.) with 0.1, 0.25, or 1.0 mg/kg of haloperidol. Two h after the injection, the rats were perfused, and the numbers of Fos i...

    journal_title：Psychiatry and clinical neurosciences

    pub_type： 杂志文章

    doi：10.1046/j.1440-1819.1998.00391.x

    authors： Suzuki M,Sun YJ,Murata M,Kurachi M

    更新日期：1998-06-01 00:00:00