[Mechanisms of plasmid-mediated resistance to quinolones].

Abstract:

:Quinolone resistance is caused mainly by chromosomal mutations in gram negative bacteria. In 1998, plasmid-mediated resistance to quinolones in clinical isolates was first reported in a Klebsiella pneumoniae strain. Locus qnr (quinolone resistance) was responsible of the quinolone resistance in this plasmid. qnr codes a protein whose function is protect both DNA-girase and topoisomerase IV from these antimicrobials. Moreover, qnr is located in an integron-like structure upstream of qacEDelta y sul1. A review of the information obtained in the last years about this mechanism of resistance was performed.

authors

Rodríguez-Martínez JM

doi

10.1157/13070406

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

25-31

issue

1

eissn

0213-005X

issn

1578-1852

pii

13070406

journal_volume

23

pub_type

杂志文章,评审
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    authors: Aznar J,Lomas M,Rodríguez-Pichardo A,Pascual A,Perea EJ

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    doi:

    authors: Sánchez C,Matamala A,Salavert M,Cuchí E,Pons M,Anglés F,Garau J

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  • Microbiological methods for surveillance of carrier status of multiresistant bacteria.

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    authors: Oteo J,Bou G,Chaves F,Oliver A

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    authors: Conejo MC,Pérez MJ,Palomares JC

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  • [Food poisoning outbreak due to the consumption of spaghetti a la carbonara caused by Salmonella enteritidis].

    abstract:INTRODUCTION:This paper reports a clinico-epidemiological and microbiological investigation conducted into an outbreak of gastrointestinal infection due to Salmonella enteritidis, where the most likely food vehicle was spaghetti a la carbonara. METHODS:An historic cohort study was conducted out among persons exposed t...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: Godoy P,Artigues A,Usera MA,González JL,Pablo N,Agustí M

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  • [Otomycosis: presentation of 15 cases].

    abstract::Fifteen cases of otomycosis in 11 women and 4 men attending the Clinic Hospital in Salamanca during the period from 1984 to 1988 are discussed. A. niger was the species isolated on the majority of occasions (73.3%). The commonest form of presentation of otomycosis was simple chronic (73.3%). The clinical pictures was ...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: Martín AM,Canut A,Muñoz S,Pescador C,Gómez JL

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  • [Variation of the incidence and antibiotic sensitivity of Neisseria gonorrhoeae in a 7-year period].

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    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: Nebreda T,Merino FJ,Campos A,Vázquez M

    更新日期:1996-08-01 00:00:00

  • Fosamprenavir (GW433908)/ritonavir in HIV-infected patients: efficacy and safety results from the Spanish Expanded Access Program.

    abstract:INTRODUCTION:The use of protease inhibitors (PI) has led to a decrease in HIV-1-related mortality and morbidity. The objective of this study was to collect safety data on treatment with fosamprenavir/ritonavir (FPV/r) 700/100mg BID in HIV-infected patients through an expanded access program. PATIENTS AND METHODS:Prosp...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/j.eimc.2008.05.002

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  • Human papillomavirus (HPV) genotype distribution in women with abnormal cervical cytology in the Basque Country, Spain.

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    pub_type: 杂志文章

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    doi:

    authors: Guerra-Romero L,Noguer I,Bolea A,Suárez M,Parras F

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    abstract:BACKGROUND:Immigration is a recent phenomenon in Spain. Certain subgroups of the immigrant population may be vulnerable to acquiring sexually transmitted infections (STI). MATERIAL AND METHODS:Descriptive study of the seroprevalenceof certain STI (HIV, hepatitis B and syphilis) and the general characteristicsn of pers...

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  • Can MALDI-TOF mass spectrometry be used with intravascular catheters?

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    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2014.01.011

    authors: Guembe M,Rodríguez-Sánchez B,Ruiz A,Martín-Rabadán P,Rodríguez-Créixems M,Bouza E

    更新日期:2014-06-01 00:00:00

  • [Orthopedic device-related infections].

    abstract::Prosthetic joint infection is an increasing public health problem. The bacterial biofilms that form on these foreign bodies are resistant to host defence mechanisms and antimicrobial therapy. Sixty per cent of prosthetic joint infections are caused by Staphylococcus sp., and they are usually acquired during surgery or...

    journal_title:Enfermedades infecciosas y microbiologia clinica

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    authors: Ariza J,Euba G,Murillo O

    更新日期:2008-06-01 00:00:00

  • [Empirical treatment of febrile episodes in patients with neutropenia in bone marrow transplantation].

    abstract::The results of therapy of febrile episodes during the pregraft phase in bone marrow transplant was retrospectively evaluated in 84 granulocytopenic patients. Most patients received co-trimoxazole and i.v. ticarcillin as antibacterial prophylaxis. 47 episodes were treated with a third generation cephalosporin plus an a...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: Pérez M,Muruzábal MJ,Gómez Casares MT,Alsar MJ,Conde E,Iriondo A,Garijo J,Richard C,Baro J,Aguado JM

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  • [Hepatitis B virus (HBV) infection in Sub-Saharan immigrants in Almería (Spain)].

    abstract:INTRODUCTION:There is scant information available in Spain regarding virological markers and clinical status in Sub-Saharan patients infected with HVB. METHODS:A cross-sectional and retrospective study of virological markers and clinical status of HBV infection in 510 adult patients from Sub-Saharan Africa, not co-inf...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2010.07.013

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  • [Colonic tuberculosis as a cause of rectal bleeding in 2 patients with HIV infection].

    abstract:BACKGROUND:Extrapulmonary tuberculosis is a relatively frequent disease in patients with HIV infection. This may be observed coinciding with pulmonary involvement or without diagnostic data of the same. Within extrapulmonary involvement, gastrointestinal involvement is one of the least frequently observed and its diagn...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:

    authors: Pintor E,Piret MV,Velasco M,Barreiro P,Ruiz M,Blanco J

    更新日期:1996-11-01 00:00:00

  • [Antibiotic ointments and methicillin-resistant Staphylococcus aureus with a reservoir in a healthcare worker in a tertiary hospital].

    abstract:BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) has become an important hospital-acquired pathogen, with transfer of the organism from a carrier or infected patient to uninfected patients by the hands or clothing of staff as the main mode of transmission. METHODS:Investigation of a cluster of new cases o...

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    pub_type: 杂志文章

    doi:10.1016/j.eimc.2012.10.002

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    pub_type: 杂志文章,实务指引

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  • [Prevalence of hepatitis virus infection markers in HIV-infected patients in Southern Spain].

    abstract:OBJECTIVES:To determine: (a) The prevalence of active infection by the hepatitis C virus (HCV) and hepatitis B virus (HBV) in HIV-infected patients, as well as previous exposure to hepatitis A virus (HAV), HBV and HCV. (b) The proportion of patients who have been vaccinated against HAV and/or HBV. (c) The HCV genotype ...

    journal_title:Enfermedades infecciosas y microbiologia clinica

    pub_type: 杂志文章

    doi:10.1016/j.eimc.2011.12.008

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  • [Demyelinating disease in human immunodeficiency virus-infected patients without severe immunodepression].

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  • [Up to date in sexually transmitted infections: epidemiology, diagnostic approaches and treatments].

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    authors: Correia S,Ponce P,Jones-Dias D,Caniça M,Igrejas G,Poeta P

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  • [Measles, mumps, and rubella vaccine. Resurgence of measles in Europe].

    abstract::Measles is a rash illness of moderate severity and high risk of serious complications, with recovery in several weeks. It is a viral disease caused by one of the most infectious and contagious pathogens that exists, whose only known reservoir is human. In 1998, the European Region of the WHO set a target of eliminatin...

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