Results of buccal mucosal grafting for patients with medically controlled ocular cicatricial pemphigoid.

Abstract:

:Eyelid surgery for patients with ocular cicatricial pemphigoid is risky when there is unchecked perioperative inflammation. The authors performed buccal mucosal grafts on 42 eyelids (23 eyes) of 17 patients with ocular cicatricial pemphigoid whose disease was controlled by systemic immunosuppression. Results were graded as: improved (12 cases, 16 eyes); satisfactory (2 cases, 2 eyes); or poor (5 patients, 5 eyes). Complications included breakthrough trichiasis, surface keratinization of the graft, blepharoptosis, phimosis, depressed eyelid blink, incomplete eyelid closure, submucosal abscess formation, and persistent nonhealing epithelial defects of the cornea. Technical errors at surgery accounted for two complications. Secondary corneal ulceration developed in two patients. The immunologic aspect of the disease flared or progressed in five patients in the postoperative period and necessitated an increase or change in systemic medication for immunosuppression. Buccal mucosal grafting shows promise in temporarily rehabilitating eyelids of some ocular cicatricial pemphigoid patients whose disease is controlled by immunosuppressive therapy.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Shore JW,Foster CS,Westfall CT,Rubin PA

doi

10.1016/s0161-6420(92)31962-1

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

383-95

issue

3

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(92)31962-1

journal_volume

99

pub_type

杂志文章
  • Orbital fat removal. Decompression for Graves orbitopathy.

    abstract:BACKGROUND:Orbital decompression has been used to describe surgical procedures that remove some portion of the orbital walls to reduce pressure on the orbital contents. Substantial morbidity associated with these procedures includes infraorbital anesthesia, worsened extraocular motility, globe displacement, and blindne...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(93)31589-7

    authors: Trokel S,Kazim M,Moore S

    更新日期:1993-05-01 00:00:00

  • Corneal endothelial changes in primary acute angle-closure glaucoma.

    abstract::In 20 patients, corneal endothelium was examined by specular microscopy after acute angle-closure glaucoma, and before any surgical treatment in order to assess possible damage during pressure induced abnormal hydration of the cornea. The mean intraocular pressure was elevated to 55 mm Hg and had lasted, on an average...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(82)34744-2

    authors: Bigar F,Witmer R

    更新日期:1982-06-01 00:00:00

  • Repair of the superior sulcus deformity using autogenous costal cartilage.

    abstract::Superior sulcus deformity is a late sequela of surgical anophthalmos. Many methods have been proposed to treat this difficult problem. A technique using autogenous costal cartilage that has resulted in satisfactory repair is presented. In addition to standard photographs and exophthalmometry measurements to follow the...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(82)34772-7

    authors: Sutula FC,Thomas O

    更新日期:1982-05-01 00:00:00

  • Genetic and Dietary Factors Influencing the Progression of Nuclear Cataract.

    abstract:PURPOSE:To determine the heritability of nuclear cataract progression and to explore prospectively the effect of dietary micronutrients on the progression of nuclear cataract. DESIGN:Prospective cohort study. PARTICIPANTS:Cross-sectional nuclear cataract and dietary measurements were available for 2054 white female t...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2016.01.036

    authors: Yonova-Doing E,Forkin ZA,Hysi PG,Williams KM,Spector TD,Gilbert CE,Hammond CJ

    更新日期:2016-06-01 00:00:00

  • Effect of topical trifluridine on Thygeson's superficial punctate keratitis.

    abstract::Six eyes of four patients with Thygeson's superficial punctate keratitis were treated with trifluridine 1% drops. Five of the six treated eyes responded favorably to topical trifluridine therapy. Symptoms and later the signs of the disease disappeared, but more slowly than observed following topical corticosteroid the...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34170-7

    authors: Nesburn AB,Lowe GH 3rd,Lepoff NJ,Maguen E

    更新日期:1984-10-01 00:00:00

  • Time course of development of posterior vitreous detachments after phacoemulsification surgery.

    abstract:PURPOSE:To determine when posterior vitreous detachments (PVDs) develop after phacoemulsification and aspiration combined with foldable intraocular lens implantation. DESIGN:Prospective, consecutive case series. PARTICIPANTS:A total of 575 eyes without a PVD preoperatively were studied prospectively and followed for ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.03.050

    authors: Hikichi T

    更新日期:2012-10-01 00:00:00

  • Ocular presentation of polyarteritis nodosa. Clinical course and management with steroid and cytotoxic therapy.

    abstract:BACKGROUND:Polyarteritis nodosa is a necrotizing vasculitis affecting medium and small-sized arteries throughout the body, including ocular tissues. Untreated polyarteritis nodosa carries a very poor prognosis. Treatment with steroids increases the 5-year survival to 48%, whereas addition of cytotoxic immunosuppressive...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(93)31405-3

    authors: Akova YA,Jabbur NS,Foster CS

    更新日期:1993-12-01 00:00:00

  • Periocular Skin Cancer in Solid Organ Transplant Recipients.

    abstract:PURPOSE:To determine the proportion of solid organ transplant recipients developing periocular nonmelanoma skin cancer and to describe the morbidity of these cancers in transplant recipients. DESIGN:Cohort study. PARTICIPANTS:Consecutive patients undergoing solid organ transplantation at the Cleveland Clinic between ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2015.09.030

    authors: Perry JD,Polito SC,Chundury RV,Singh AD,Fritz MA,Vidimos AT,Gastman BR,Koyfman SA

    更新日期:2016-01-01 00:00:00

  • Management of infectious endophthalmitis.

    abstract::Diagnostic anterior chamber and vitreous aspiration confirmed an infectious etiology in 78 of 140 eyes (56%) with suspected endophthalmitis. In 27 eyes the vitreous aspirate was positive, while the anterior chamber aspirate was negative. Intraocular antibiotics were used in 88 eyes including 50 which underwent therape...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(80)35241-x

    authors: Forster RK,Abbott RL,Gelender H

    更新日期:1980-04-01 00:00:00

  • Results at 2 Years after Gene Therapy for RPE65-Deficient Leber Congenital Amaurosis and Severe Early-Childhood-Onset Retinal Dystrophy.

    abstract:PURPOSE:To provide an initial assessment of the safety of a recombinant adeno-associated virus vector expressing RPE65 (rAAV2-CB-hRPE65) in adults and children with retinal degeneration caused by RPE65 mutations. DESIGN:Nonrandomized, multicenter clinical trial. PARTICIPANTS:Eight adults and 4 children, 6 to 39 years...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1016/j.ophtha.2016.03.003

    authors: Weleber RG,Pennesi ME,Wilson DJ,Kaushal S,Erker LR,Jensen L,McBride MT,Flotte TR,Humphries M,Calcedo R,Hauswirth WW,Chulay JD,Stout JT

    更新日期:2016-07-01 00:00:00

  • Diagnostic accuracy of pattern electroretinogram optimized for glaucoma detection.

    abstract:PURPOSE:To assess the ability of the new pattern electroretinogram optimized for glaucoma detection (PERGLA) paradigm to discriminate between healthy individuals and individuals with glaucomatous optic neuropathy (GON). DESIGN:Cross-sectional study. PARTICIPANTS:One hundred forty-two eyes of 71 participants (42 healt...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2008.10.026

    authors: Bowd C,Vizzeri G,Tafreshi A,Zangwill LM,Sample PA,Weinreb RN

    更新日期:2009-03-01 00:00:00

  • Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.

    abstract:PURPOSE:To analyze the prevalence, incidence, and clinical characteristics of eyes with geographic atrophy (GA) in age-related macular degeneration (AMD), including clinical and genetic factors affecting enlargement. DESIGN:Prospective cohort study within a controlled clinical trial. PARTICIPANTS:Age-Related Eye Dise...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2018.05.028

    authors: Keenan TD,Agrón E,Domalpally A,Clemons TE,van Asten F,Wong WT,Danis RG,Sadda S,Rosenfeld PJ,Klein ML,Ratnapriya R,Swaroop A,Ferris FL 3rd,Chew EY,AREDS2 Research Group.

    更新日期:2018-12-01 00:00:00

  • Diabetes can alter the interpretation of visual dysfunction in ocular hypertension.

    abstract:PURPOSE:The authors examined the influences of diabetes on the results of visual function testing in patients with ocular hypertension (OHT). METHODS:Color vision (desaturated D-15), contrast sensitivity together with both transient and steady-state pattern electroretinogram (PERG) findings from patients with document...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(96)30489-2

    authors: Vesti E,Trick GL

    更新日期:1996-09-01 00:00:00

  • The Increasing Burden of Myopia in Israel among Young Adults over a Generation: Analysis of Predisposing Factors.

    abstract:PURPOSE:To determine the trends in prevalence of myopia in Israeli young adults over approximately a generation, as well as associated factors and variation in the impact of these factors on myopia prevalence in this region over time. DESIGN:Retrospective, cross-sectional study. PARTICIPANTS:One hundred four thousand...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2019.06.025

    authors: Shapira Y,Mimouni M,Machluf Y,Chaiter Y,Saab H,Mezer E

    更新日期:2019-12-01 00:00:00

  • Influence of the vitreomacular interface on outcomes of ranibizumab therapy in neovascular age-related macular degeneration.

    abstract:PURPOSE:To investigate the influence of the vitreomacular interface (VMI) on the functional and anatomic efficacy of ranibizumab therapy in patients with neovascular age-related macular degeneration (AMD). DESIGN:Subanalysis of a prospective, 12-month, multicenter, phase IIIb trial. PARTICIPANTS:A total of 353 treatm...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2013.05.032

    authors: Mayr-Sponer U,Waldstein SM,Kundi M,Ritter M,Golbaz I,Heiling U,Papp A,Simader C,Schmidt-Erfurth U

    更新日期:2013-12-01 00:00:00

  • Severity of scleritis and episcleritis.

    abstract:PURPOSE:Inflammation of the wall of the eyeball may extend to adjacent ocular tissues with blinding consequences and may be associated with potentially lethal systemic disorders. This study was undertaken to evaluate the ocular complications and systemic disease associations of the different types of scleritis and epis...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(94)31325-x

    authors: Sainz de la Maza M,Jabbur NS,Foster CS

    更新日期:1994-02-01 00:00:00

  • Treatment outcomes in malignant glaucoma.

    abstract:PURPOSE:To report treatment outcomes in malignant glaucoma. DESIGN:Retrospective case series. PARTICIPANTS:Twenty-eight eyes of 26 patients who were treated for malignant glaucoma between 1991 and 2009. METHODS:Malignant glaucoma was diagnosed based on the presence of a shallow or flat central and peripheral anterio...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.10.024

    authors: Dave P,Senthil S,Rao HL,Garudadri CS

    更新日期:2013-05-01 00:00:00

  • Methotrexate treatment for sarcoid-associated panuveitis.

    abstract:OBJECTIVE:To determine the safety and efficacy of low-dose methotrexate (MTX) for sarcoid-associated panuveitis. DESIGN:Retrospective noncomparative case series. PARTICIPANTS:Twenty eyes from 11 patients were analyzed. Eight patients had sarcoidosis. Three patients were clinically suspected of sarcoidosis despite neg...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章

    doi:10.1016/S0161-6420(99)90011-8

    authors: Dev S,McCallum RM,Jaffe GJ

    更新日期:1999-01-01 00:00:00

  • The Endophthalmitis Vitrectomy Study. Relationship between clinical presentation and microbiologic spectrum.

    abstract:PURPOSE:The authors determine if specific features of the clinical presentation of acute postoperative endophthalmitis correlated with the microbiologic culture results. METHODS:A total of 420 patients who had clinical evidence of endophthalmitis within 6 weeks after cataract surgery or secondary intraocular lens impl...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0161-6420(97)30326-1

    authors: Johnson MW,Doft BH,Kelsey SF,Barza M,Wilson LA,Barr CC,Wisniewski SR

    更新日期:1997-02-01 00:00:00

  • Comparison of optical coherence tomography assessments in the comparison of age-related macular degeneration treatments trials.

    abstract:OBJECTIVE:To determine agreement between spectral-domain (SD) and time-domain (TD) optical coherence tomography (OCT) image assessments by certified readers in eyes treated for neovascular age-related macular degeneration (AMD). DESIGN:Cross-sectional study within the Comparison of AMD Treatments Trials (CATT). PARTI...

    journal_title:Ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ophtha.2014.04.020

    authors: Folgar FA,Jaffe GJ,Ying GS,Maguire MG,Toth CA,Comparison of Age-Related Macular Degeneration Treatments Trials Research Group.

    更新日期:2014-10-01 00:00:00

  • Bilateral orbital involvement in fatal giant cell polymyositis.

    abstract::The case of a young woman with giant cell polymyositis is described. She had bilateral, severe, midly painful proptosis and ophthalmoplegia. Extensive pharyngeal, laryngeal, and cardiac muscle involvement occurred 18 months later coincident with fatal cardiac arrhythmia. At autopsy, extensive muscle necrosis and giant...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(90)32554-x

    authors: Kattah JC,Zimmerman LE,Kolsky MP,Chrousos G,Chavis R,Jaffe G,Manz HJ

    更新日期:1990-04-01 00:00:00

  • Plaque radiotherapy in the management of retinoblastoma. Use as a primary and secondary treatment.

    abstract:BACKGROUND:Radioactive episcleral plaque brachytherapy is a treatment method for selected retinoblastomas. The authors have used this technique since 1976 as both a primary and a secondary treatment method after other methods failed to achieve tumor control. METHODS:A review of the records of 400 consecutive children ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(93)31667-2

    authors: Shields CL,Shields JA,De Potter P,Minelli S,Hernandez C,Brady LW,Cater JR

    更新日期:1993-02-01 00:00:00

  • Initial experience using the transconjunctival sutureless vitrectomy system for vitreoretinal surgery.

    abstract:OBJECTIVE:To describe the initial experience and to evaluate the safety and feasibility of using the 25-gauge Transconjunctival Sutureless Vitrectomy System (TSV) for a variety of vitreoretinal procedures. DESIGN:Retrospective review of a consecutive interventional case series. PARTICIPANTS:Thirty-five eyes of 33 pat...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(02)01119-3

    authors: Fujii GY,De Juan E Jr,Humayun MS,Chang TS,Pieramici DJ,Barnes A,Kent D

    更新日期:2002-10-01 00:00:00

  • Evaluation of retinal nerve fiber layer progression in glaucoma: a comparison between the fast and the regular retinal nerve fiber layer scans.

    abstract:OBJECTIVE:To compare the performance of the fast (256 A-scans in each scan circle) and the regular (512 A-scans in each scan circle) retinal nerve fiber layer (RNFL) scan protocols for detection of glaucoma progression using the Stratus optical coherence tomography (OCT) device (Carl Zeiss Meditec, Dublin, CA). DESIGN...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2010.08.014

    authors: Leung CK,Cheung CY,Weinreb RN,Liu S,Ye C,Lai G,Liu N,Pang CP,Tse KK,Lam DS

    更新日期:2011-04-01 00:00:00

  • Palpebral fissure height and downgaze in patients with Graves upper eyelid retraction and congenital blepharoptosis.

    abstract:PURPOSE:To compare the relation between vertical eyelid fissure height and downgaze in healthy subjects and in patients with Graves upper eyelid retraction and congenital blepharoptosis. METHODS:With a caliper rule, the authors measured the vertical eyelid fissure height of 25 patients with no previous history of eye ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(95)30887-1

    authors: Guimarães FC,Cruz AA

    更新日期:1995-08-01 00:00:00

  • A phase I/II study of subconjunctival carboplatin for intraocular retinoblastoma.

    abstract:PURPOSE:To evaluate the efficacy and toxicity of subconjunctival carboplatin for intraocular retinoblastoma. DESIGN:A phase I/II clinical trial (noncomparative case series). PARTICIPANTS:Eleven children with bilateral retinoblastoma who had 13 eyes containing active tumor. METHODS:Subconjunctival carboplatin (1.4-2....

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章

    doi:10.1016/S0161-6420(99)90406-2

    authors: Abramson DH,Frank CM,Dunkel IJ

    更新日期:1999-10-01 00:00:00

  • Growth features of choroidal neovascular membranes in age-related macular degeneration.

    abstract::The authors studied 80 eyes of patients with choroidal neovascular membranes (CNVMs) associated with age-related macular degeneration between 1982 and 1988. In each case, fluorescein angiography was done on two occasions separated by an interval of 2 days to 11 weeks (average, 13 days) without intervening photocoagula...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(89)32741-2

    authors: Klein ML,Jorizzo PA,Watzke RC

    更新日期:1989-09-01 00:00:00

  • Phacoemulsification and silicone oil removal through a single corneal incision.

    abstract:OBJECTIVE:Cataracts are a frequent complication after silicone oil infusion for the repair of complicated retinal detachments, occurring in up to 100% of eyes retaining silicone oil for 6 months or more. The authors devised a combined procedure for cataract and silicone oil removal with intraocular lens (IOL) implantat...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(98)91119-8

    authors: Larkin GB,Flaxel CJ,Leaver PK

    更新日期:1998-11-01 00:00:00

  • Orbital Angiogenesis and Lymphangiogenesis in Thyroid Eye Disease: An Analysis of Vascular Growth Factors with Clinical Correlation.

    abstract:PURPOSE:The human orbit is an environment that is vulnerable to inflammation and edema in the setting of autoimmune thyroid disease. Our study investigated the tenet that orbital adipose tissue lacks lymphatic vessels and analyzed the clinicopathologic differences between patients with acute and chronic thyroid eye dis...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2016.05.052

    authors: Wong LL,Lee NG,Amarnani D,Choi CJ,Bielenberg DR,Freitag SK,D'Amore PA,Kim LA

    更新日期:2016-09-01 00:00:00

  • Prognostic factors in vitrectomy for epiretinal membranes of the macula.

    abstract::A retrospective multivariate analysis of 264 consecutive cases of vitrectomy for removal of epiretinal membranes of the macula was performed. Two main preoperative prognostic factors were identified that were associated with the visual outcome of surgery: (1) the preoperative visual acuity, and (2) the duration of blu...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(86)33689-3

    authors: Rice TA,De Bustros S,Michels RG,Thompson JT,Debanne SM,Rowland DY

    更新日期:1986-05-01 00:00:00