Abstract:
:In 20 patients, corneal endothelium was examined by specular microscopy after acute angle-closure glaucoma, and before any surgical treatment in order to assess possible damage during pressure induced abnormal hydration of the cornea. The mean intraocular pressure was elevated to 55 mm Hg and had lasted, on an average, 47 (5--192) hours. The mean endothelial cell density in the affected eye was 1534 and in the nonaffected fellow eye 2243 cells/mm2 (mean decrease 33%, P = 0.002). The amount of cell loss correlates with the duration of the intraocular pressure increase. Thirty-five percent of these patients presented a bilateral cornea guttata. This high incidence of endothelial dystrophy was confirmed in a retrospective specular microscopic study in 20 patients with a history of unilateral acute angle-closure glaucoma. The decreased number of endothelial cells after acute angle-closure glaucoma frequently combined with bilateral cornea guttata, accounts for the corneal degeneration in these patients following a later cataract extraction.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Bigar F,Witmer Rdoi
10.1016/s0161-6420(82)34744-2subject
Has Abstractpub_date
1982-06-01 00:00:00pages
596-9issue
6eissn
0161-6420issn
1549-4713pii
S0161-6420(82)34744-2journal_volume
89pub_type
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