Corneal endothelial changes in primary acute angle-closure glaucoma.

Abstract:

:In 20 patients, corneal endothelium was examined by specular microscopy after acute angle-closure glaucoma, and before any surgical treatment in order to assess possible damage during pressure induced abnormal hydration of the cornea. The mean intraocular pressure was elevated to 55 mm Hg and had lasted, on an average, 47 (5--192) hours. The mean endothelial cell density in the affected eye was 1534 and in the nonaffected fellow eye 2243 cells/mm2 (mean decrease 33%, P = 0.002). The amount of cell loss correlates with the duration of the intraocular pressure increase. Thirty-five percent of these patients presented a bilateral cornea guttata. This high incidence of endothelial dystrophy was confirmed in a retrospective specular microscopic study in 20 patients with a history of unilateral acute angle-closure glaucoma. The decreased number of endothelial cells after acute angle-closure glaucoma frequently combined with bilateral cornea guttata, accounts for the corneal degeneration in these patients following a later cataract extraction.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Bigar F,Witmer R

doi

10.1016/s0161-6420(82)34744-2

subject

Has Abstract

pub_date

1982-06-01 00:00:00

pages

596-9

issue

6

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(82)34744-2

journal_volume

89

pub_type

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