Aortic stiffness is an independent predictor of left ventricular function in patients with coronary heart disease.

Abstract:

:Although aortic stiffness plays an important role in patients with coronary artery disease (CAD), the influence of aortic stiffness on left ventricular systolic function has not yet been fully evaluated. In the present study, we measured brachial-ankle pulse wave velocity (baPWV), which is a new index of aortic stiffness, in patients with CAD (CAD group, n = 170, 67 +/- 9 years old) and without CAD (non-CAD group, n = 81, 63 +/- 8 years old), and evaluated the relationship between baPWV and left ventricular systolic function in patients with CAD. baPWV in the CAD group was significantly higher than that in the non-CAD group (1,794 +/- 350 vs. 1,469 +/- 292 cm/s, p < 0.05), although both systolic and diastolic blood pressure were comparable between the two groups. In the CAD group, the baPWV was higher in patients with three-vessel disease than that in patients with one-vessel disease (1,885 +/- 542 vs. 1,720 +/- 373 cm/s, p < 0.05). In the CAD group, multivariate analysis demonstrated that baPWV and pulse pressure independently correlated with left ventricular ejection fraction (LVEF). In conclusion, in patients with CAD, baPWV, which is a simple marker of aortic stiffness, increases with CAD severity and correlates with left ventricular systolic function independent of CAD severity.

journal_name

Cardiology

journal_title

Cardiology

authors

Sakuragi S,Iwasaki J,Tokunaga N,Hiramatsu S,Ohe T

doi

10.1159/000082472

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

107-12

issue

2

eissn

0008-6312

issn

1421-9751

pii

82472

journal_volume

103

pub_type

杂志文章
  • Comparative hemodynamic effects of intravenous digoxin and enoximone in severe chronic heart failure.

    abstract::In order to compare the acute hemodynamic effects of digoxin (0.01 mg/kg) and enoximone (1 mg/kg), a phosphodiesterase inhibitor inotropic agent, in severe chronic congestive heart failure, 8 patients (male, mean age 56.7 years, sinus rhythm) were investigated with a randomized cross-over study. Peak effect of enoximo...

    journal_title:Cardiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000176702

    authors: Casella G,Cantelli I,Pavesi PC,Barbato G,Bracchetti D

    更新日期:1994-01-01 00:00:00

  • Peripheral arterial-vascular disease in women: prevalence, prognosis, and treatment.

    abstract::Lower extremity atherosclerosis results in significant morbidity in women, particularly in women following the menopause. Up to 25% of women aged 55 to 74 years are affected by this disease. When noninvasive testing is used to determine the prevalence of lower extremity atherosclerosis, and men in this age group are e...

    journal_title:Cardiology

    pub_type: 杂志文章,评审

    doi:10.1159/000176899

    authors: Gerhard M,Baum P,Raby KE

    更新日期:1995-01-01 00:00:00

  • Glycoprotein IIb/IIIa inhibitor-associated thrombocytopenia: clinical predictors and effect on outcome.

    abstract::Glycoprotein IIb/IIIa inhibitors are used as an adjunct to antiplatelet therapy in percutaneous coronary intervention to reduce postprocedural enzyme elevations. Previous studies have shown a risk for thrombocytopenia that is associated with these agents. We sought to evaluate the incidence and outcomes of glycoprotei...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000081008

    authors: George BJ,Eckart RE,Shry EA,Simpson DE

    更新日期:2004-01-01 00:00:00

  • A case of pulmonary alveolar microlithiasis with cardiac constriction secondary to severe adjacent pleural involvement.

    abstract::Pulmonary alveolar microlithiasis (PAM) is a rare disorder of uncertain etiology and pathogenesis that is characterized by tiny calcium phosphate depositions in lung alveoli. Ectopic organ involvement has been reported infrequently. We hereby present a patient with PAM complicated by severe pleural calcification that ...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000095420

    authors: Kacmaz F,Alyan O,Celenk M,Ozdemir O,Turkvatan A,Dogan M,Ilkay E

    更新日期:2007-01-01 00:00:00

  • Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis.

    abstract::We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). T...

    journal_title:Cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000088106

    authors: Lee SH,Ko YG,Jang Y,Kwon HM,Lee SH,Yoon JH,Park SH,Kim BO,Jeon DW,Yang JY,Ryu SK,Korean Multicenter Angioplasty Team (KOMATE) Investigators.

    更新日期:2005-01-01 00:00:00

  • Haemodynamic changes in essential hypertension in young subjects.

    abstract::The haemodynamic changes in essential hypertension were investigated in 7 girls and 4 boys under the age of 18 years. The Fick method was used for the estimation of cardiac output (CO). The cardiac indices (CIs) ranged form 2.8 to 6.6 litres/min/m2 and the total peripheral resistance (TPR) from 1,100 to 2,860 dyn/s/cm...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000173507

    authors: Uhari M,Paavilainen T

    更新日期:1982-01-01 00:00:00

  • Sleep quality and quality of life in patients with hypertrophic cardiomyopathy.

    abstract:OBJECTIVES:To evaluate clinical predictors of poor sleep quality and quality of life (QOL) in patients with hypertrophic cardiomyopathy (HCM). METHODS:Consecutive stable patients with HCM were evaluated for the risk of obstructive sleep apnea (OSA) by the Berlin Questionnaire, daytime sleepiness by the Epworth Sleepin...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000321718

    authors: Pedrosa RP,Lima SG,Drager LF,Genta PR,Amaro AC,Antunes MO,Arteaga E,Mady C,Lorenzi-Filho G

    更新日期:2010-01-01 00:00:00

  • The multitasking role of macrophages in Stanford type A acute aortic dissection.

    abstract:OBJECTIVES:The aim of the study was to determine whether the release by macrophages of matrix metalloproteinase (MMP)-12 and vascular endothelial growth factor (VEGF) - leading to inflammation, matrix degradation and neoangiogenesis - represents an effective pathway that underlies aortic wall remodeling in Stanford typ...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000355253

    authors: Del Porto F,di Gioia C,Tritapepe L,Ferri L,Leopizzi M,Nofroni I,De Santis V,Della Rocca C,Mitterhofer AP,Bruno G,Taurino M,Proietta M

    更新日期:2014-01-01 00:00:00

  • Digitalis Therapy and Risk of Recurrent Ventricular Tachyarrhythmias and ICD Therapies in Atrial Fibrillation and Heart Failure.

    abstract:OBJECTIVE:This study sought to assess the impact of treatment with digitalis on recurrences of ventricular tachyarrhythmias in implantable cardioverter defibrillator (ICD) recipients with atrial fibrillation (AF) and heart failure (HF). BACKGROUND:The data regarding outcomes of digitalis therapy in ICD recipients are ...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000497271

    authors: Schupp T,Behnes M,Weiss C,Nienaber C,Reiser L,Bollow A,Taton G,Reichelt T,Ellguth D,Engelke N,Rusnak J,Weidner K,Akin M,Mashayekhi K,Borggrefe M,Akin I

    更新日期:2019-01-01 00:00:00

  • Recurrent preexcited reciprocating tachycardia, concealed ventricular preexcitation and conduction disturbances in the normal atrioventricular pathway in a newborn.

    abstract::We describe a newborn infant with concealed ventricular preexcitation in sinus rhythm on the early ECGs, and who developed recurrent episodes of preexcited reciprocating tachycardia. Manifestation of the ventricular preexcitation and initiation of the tachycardias were dependent on the presence of severe conduction di...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000173991

    authors: Belhassen B,Pardo J,Peled B,Blieden L,Laniado S

    更新日期:1986-01-01 00:00:00

  • Advanced atrioventricular block and complete left bundle branch block in a case of Takayasu's aortitis.

    abstract::A 56-year-old woman, who had received an aortic valve replacement suffered from complete left bundle branch block and advanced atrioventricular block. On the basis of marked systemic inflammatory findings on admission and histopathological findings on previous cardiac surgery, this patient was considered to have condu...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000174579

    authors: Naitoh M,Chino M,Sakai T,Saitoh S,Ohkura M,Nishikawa K

    更新日期:1990-01-01 00:00:00

  • Prognostic information from on-line vectorcardiography in unstable angina pectoris.

    abstract::The prognostic information from 24-hour monitoring with on-line vectorcardiography (VCG) was assessed in 100 patients with a clinical diagnosis of unstable angina pectoris. ST change vector magnitude, ST vector magnitude and QRS vector difference were monitored. During a follow-up period of 343 +/- 77 days, 7 patients...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000176832

    authors: Lundin P,Eriksson SV,Fredrikson M,Rehnqvist N

    更新日期:1995-01-01 00:00:00

  • Clinical, angiographic and hemodynamic characteristics of patients with a strongly positive exercise test.

    abstract::To determine the clinical, angiographic and hemodynamic characteristics of patients with a strongly positive exercise test, 37 subjects demonstrating greater than or equal to 3 mm S-T segment depression were identified among 892 consecutive diagnostic treadmill evaluations. Typical angina by history was present in 78%...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000170871

    authors: Williams DO,Most AS

    更新日期:1980-01-01 00:00:00

  • The use of ticagrelor in a patient at increased risk of stent thrombosis resistant to multiple thienopyridines.

    abstract::Ticagrelor has been shown to be superior to clopidogrel in patients presenting with acute myocardial infarction who undergo early invasive treatment. We discuss a hitherto unreported use of ticagrelor in the management of a patient resistant to multiple thienopyridines at high risk of stent thrombosis. ...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000329916

    authors: Morgan KP,More RS,Chauhan A

    更新日期:2011-01-01 00:00:00

  • Accessory mitral valve tissue: report of two asymptomatic cases.

    abstract::Accessory mitral valve tissue is a rare anomaly of embryologic development of the endocardial cushion and may cause substantial and progressive obstruction of the left ventricular outflow tract. Subaortic obstruction resulting from accessory mitral tissue is most likely due to systolic ballooning of the tissue into th...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000091290

    authors: Uslu N,Gorgulu S,Yildirim A,Eren M

    更新日期:2006-01-01 00:00:00

  • QT prolongation and torsade de pointes induced by fluoroquinolones: infrequent side effects from commonly used medications.

    abstract::Although very useful agents, fluoroquinolones are associated with a number of adverse events, some with considerable clinical significance. Prolongation of the QT interval, for example, is an adverse effect associated with the use of fluoroquinolones. Fluoroquinolones prolong the QT interval by blocking voltage-gated ...

    journal_title:Cardiology

    pub_type: 杂志文章,评审

    doi:10.1159/000334441

    authors: Briasoulis A,Agarwal V,Pierce WJ

    更新日期:2011-01-01 00:00:00

  • Soluble VCAM-1 and E-selectin, but not ICAM-1 discriminate endothelial injury in patients with documented coronary artery disease.

    abstract::It has been shown that endothelial cell adhesion molecules play an important role in the development of coronary atherosclerosis and inflammatory disease. We sought to test whether soluble vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1) and E-selectin are increased in patients wi...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000006995

    authors: Semaan HB,Gurbel PA,Anderson JL,Muhlestein JB,Carlquist JF,Horne BD,Serebruany VL

    更新日期:2000-01-01 00:00:00

  • The value of combining CYP2C19*2 polymorphism with classic risk factors in prediction of clinical prognosis in acute coronary syndrome patients.

    abstract:OBJECTIVES:To assess the impact of different CYP2C19*2 polymorphisms on clinical outcomes and the effects of CYP2C19*2 polymorphism on predicting clinical outcomes in association with classic risk factors in patients with acute coronary syndromes (ACS). METHODS:Between July 2008 and September 2009, 497 consecutive pat...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000329048

    authors: Yan SD,Chen M,Li Q,Liu XJ,Peng Y,Chai H,Xu YN,Wei JF,Huang DJ

    更新日期:2011-01-01 00:00:00

  • Sex Influence on the Efficacy and Safety of Sacubitril/Valsartan.

    abstract:BACKGROUND:Women are underrepresented in sacubitril/valsartan (SV) clinical trials. The aim of this study was to assess sex-specific differences in efficacy, tolerability, and safety of SV in real-world heart failure with reduced ejection fraction (HFrEF) patients. METHODS:A prospective registry in 10 centers includin...

    journal_title:Cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000498984

    authors: Vicent L,Ayesta A,Esteban-Fernández A,Gómez-Bueno M,De-Juan J,Díez-Villanueva P,Iniesta ÁM,Rojas-González A,Bover-Freire R,Iglesias D,García-Aguado M,Perea-Egido JA,Martínez-Sellés M

    更新日期:2019-01-01 00:00:00

  • Detection of the earliest ventricular contraction site in patients with Wolff-Parkinson-White syndrome using two-dimensional guided M-mode tissue Doppler echocardiography.

    abstract:OBJECTIVE:The purpose of this study was to examine the feasibility of M-mode tissue Doppler imaging for localizing the accessory pathway in patients with Wolff-Parkinson-White (WPW) syndrome. METHODS:Two-dimensional guided tissue Doppler M-mode was recorded at the mitral and tricuspid annular levels in 13 WPW patients...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000006970

    authors: Nagai H,Takata S,Sakagami S,Furusho H,Takamura M,Yuasa T,Kobayashi K

    更新日期:1999-01-01 00:00:00

  • Early Repolarization Pattern and Left Ventricular Mass in Hypertrophic Cardiomyopathy.

    abstract:BACKGROUND:J-point elevation in the inferior and/or lateral leads is associated with an increased incidence of sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM), although the exact underlying mechanism is not known. As severe left ventricular hypertrophy and late gadolinium enhancement (LGE) are important...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000505639

    authors: Azevedo PMO,Guerreiro C,Ladeiras-Lopes R,Ferreira N,Faria R,Barbosa R,Primo J,Braga J

    更新日期:2020-01-01 00:00:00

  • Ventriculo-atrial conduction associated with ventricular premature beats. Study with his bundle electrography.

    abstract::In a group of eight patients with ventricular premature beats, ventriculoatrial conduction, with retrograde activation of the His bundle and the atria could be demonstrated by His bundle electrograms in four subjects. All had early ventricular premature beats with coupling indices between 210 and 350 msec. In the othe...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000169687

    authors: Gavrilescu S,Luca C

    更新日期:1974-01-01 00:00:00

  • When an MI is not an MI: a case of varicella zoster myocarditis.

    abstract::A sixteen-year-old male presented with symptoms and investigations suggestive of acute myocardial infarction. The patient had suffered from a varicella zoster infection 5 days prior to presentation. Varicella myocarditis was suspected and diagnosed following treatment and positive varicella serology. This case highlig...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000106682

    authors: Kelly E,Cullen G,McGurk C

    更新日期:2008-01-01 00:00:00

  • Congenital prolongation of Q-T interval: a family study of three generations.

    abstract::Three generations of a family with the Romano-Ward syndrome are described. Of all the affected members, only 1 was symptomatic, experiencing episodes of syncope proven to be due to polymorphous ventricular tachycardia (PMVT) induced by chlorimipramine treatment for depression. During treatment of an episode of PMVT wi...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000173500

    authors: Flugelman MY,Pollack S,Hammerman H,Riss E,Barzilai D

    更新日期:1982-01-01 00:00:00

  • Cardiovascular changes in awake dogs caused by suddenly induced aortic hypertension.

    abstract::Cardiovascular adaptation to the sudden inflation of a balloon in the descending aorta was investigated in intact awake, standing dogs. The balloon inflation raised pressure in the arterial bed proximal from the balloon. Initially, it lowered heart rate and cardiac output. After 4 sec, heart rate and cardiac output be...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000169905

    authors: Ehrlich W,Rodriguez-Lopez E

    更新日期:1978-01-01 00:00:00

  • Short- and long-term prognosis after coronary artery bypass grafting in relation to smoking habits.

    abstract::We describe the 2- and 5-year prognoses following coronary artery bypass grafting (CABG) in relation to smoking habits among consecutive patients being operated on in western Sweden during a 3-year period. Among the 2,121 patients, 10.2% admitted smoking at coronary angiography as compared with 7.5% 2 years after CABG...

    journal_title:Cardiology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1159/000177397

    authors: Herlitz J,Haglid M,Albertsson P,Westberg S,Karlson BW,Hartford M,Lurje L,Caidahl K

    更新日期:1997-11-01 00:00:00

  • Burden of late repeat hospitalization in patients undergoing angioplasty or bypass surgery. A long-term (13 years) report from the Lady Davis Carmel Medical Center registry.

    abstract::We investigated the incidence and determinants of early and late repeat hospitalization for cardiac causes in 378 patients following myocardial revascularization [199 coronary balloon angioplasty (PTCA), 179 coronary bypass surgery (CABG)] in a single cardiovascular center and followed for a median period of 13 years....

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000064681

    authors: Halon DA,Rennert HS,Flugelman MY,Jaffe R,Lewis BS

    更新日期:2002-01-01 00:00:00

  • Diabetic nephropathy, percutaneous coronary interventions, and blockade of the renin-angiotensin system.

    abstract::Since recent studies demonstrated an impaired outcome after percutaneous coronary interventions (PCI) in patients with chronic renal failure but did not address the aetiology of renal failure, we now analysed the outcome of patients with diabetic nephropathy in 721 consecutive patients undergoing PCI. Diabetic nephrop...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000086050

    authors: Reinecke H,Matzkies F,Fobker M,Breithardt G,Schaefer RM

    更新日期:2005-01-01 00:00:00

  • Protection of the ventricular parasystolic focus due to interference of sinus and parasystolic impulses in the ventricular-ectopic junction.

    abstract::A 50-year-old man with intermittent ventricular parasystolic bigeminy is reported in whom the parasystolic focus was protected from late intervening sinus impulses. This is the first report to suggest the presence of protection due to interference in parasystolic bigeminy. The findings in this case suggest that when a...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000174583

    authors: Kinoshita S,Konishi G,Kinoshita Y

    更新日期:1990-01-01 00:00:00

  • Frequency, risk factors and prognosis of postoperative hyperbilirubinemia after heart valve surgery.

    abstract:OBJECTIVES:Despite recent advances in cardiovascular surgery, hyperbilirubinemia after heart valve surgery occurs often and the mechanism is not well clarified. We evaluated the incidence and nature of postoperative hyperbilirubinemia in heart valve surgery patients to analyze its risk factors and to identify its clini...

    journal_title:Cardiology

    pub_type: 杂志文章

    doi:10.1159/000338142

    authors: Nishi H,Sakaguchi T,Miyagawa S,Yoshikawa Y,Fukushima S,Saito S,Ueno T,Kuratani T,Sawa Y

    更新日期:2012-01-01 00:00:00