Effectiveness of bupropion as an aid to stopping smoking before elective surgery: a randomised controlled trial.

Abstract:

:Smoking is a risk factor for complications during and after surgery, but most smokers are unable to quit before elective surgery. We tested the efficacy of bupropion in improving smoking cessation rates in this setting by enrolling 47 patients from the elective surgery waiting list in a double-blind randomised controlled trial. Patients receiving bupropion had a lower daily cigarette consumption at the time of hospital admission, median (IQR) cigarettes per day: 6 (2-7) vs. 15 (9-20), p = 0.046. They also had a reduction in end-expired carbon monoxide (p = 0.004), a known contaminant of cigarette smoke, and increased arterial oxygen saturation on pulse oximetry (p = 0.011). They were more likely to have stopped smoking at the 3-week visit (p = 0.036), but not at the 6-week visit (p = 0.25) or at the time of hospital admission for surgery (p > 0.99). This study found that smokers waiting for elective surgery are more likely to reduce or stop smoking when treated with bupropion.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Myles PS,Leslie K,Angliss M,Mezzavia P,Lee L

doi

10.1111/j.1365-2044.2004.03943.x

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

1053-8

issue

11

eissn

0003-2409

issn

1365-2044

pii

2004357

journal_volume

59

pub_type

临床试验,杂志文章,多中心研究,随机对照试验
  • The relationship between anaesthetic uptake and cardiac output.

    abstract::The hypothesis that anaesthetic uptake during maintenance of anaesthesia is related to cardiac output was tested on 21 patients undergoing cardiac surgery. Using a computer-controlled closed breathing system, enflurane was administered to maintain an end-expired concentration of 1%. Cardiac output was measured by ther...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1996.tb07648.x

    authors: Watt SJ,Cook LB,Ohri S,Lockwood GG

    更新日期:1996-01-01 00:00:00

  • Prediction of prolonged laryngoscopy.

    abstract::Duration of laryngoscopy must be kept as short as possible to prevent disturbances of oxygenation and ventilation. Because the factors associated with prolonged laryngoscopy are not well known, we studied 1000 patients undergoing tracheal intubation under general anaesthesia to determine the possible effects of their ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2001.02084-5.x

    authors: Saghaei M,Safavi MR

    更新日期:2001-12-01 00:00:00

  • Haemodynamic and catecholamine stress responses to the Laryngeal Tube-Suction Airway and the Proseal Laryngeal Mask Airway.

    abstract::Supraglottic airway devices such as the ProSeal Laryngeal Mask Airway (PLMA) and Laryngeal Tube-Suction Airway (LTS) that provoke the least stress responses could be beneficial in many situations, especially in patients with cardiovascular disease. We compared the haemodynamic and catecholamine stress response of the ...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2006.04548.x

    authors: Dahaba AA,Prax N,Gaube W,Gries M,Rehak PH,Metzler H

    更新日期:2006-04-01 00:00:00

  • Effect site concentration during propofol TCI sedation: a comparison of sedation score with two pharmacokinetic models.

    abstract::Target controlled infusion (TCI) pumps function using a programme based on a pharmacokinetic/pharmacodynamic model. We compared the Marsh and Schnider models to find out which better correlates with the clinically observed effect of propofol as assessed by the Observer Assessment of Alertness/Sedation (OAAS) score and...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2007.05059.x

    authors: Barakat AR,Sutcliffe N,Schwab M

    更新日期:2007-07-01 00:00:00

  • The incidence of Horner's syndrome during lumbar extradural for elective Caesarean section and provision of analgesia during labour.

    abstract::One hundred and fifty women in labour provided with extradural analgesia were monitored and an incidence of Horner's syndrome of 1.33% was noted. Fifty women undergoing Caesarean section under extradural analgesia were also monitored and an incidence of Horner's syndrome of 4% was noted. From the results we found it i...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:

    authors: Clayton KC

    更新日期:1983-06-01 00:00:00

  • Pleural surgery in patients with cystic fibrosis. A review of anaesthetic management.

    abstract::Eighteen patients with advanced cystic fibrosis complicated by pneumothorax required either pleurectomy or abrasion pleurodesis. Anaesthesia with nitrous oxide and oxygen was combined with controlled ventilation to both lungs, usually through a double lumen endobronchial tube. Spontaneous ventilation was restored at t...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1984.tb06473.x

    authors: Robinson DA,Branthwaite MA

    更新日期:1984-07-01 00:00:00

  • Insertion methods of the laryngeal mask airway. A survey of current practice in Wales.

    abstract::The efficacy of the laryngeal mask is widely accepted, but there is a lack of consensus on the best insertion method and on the use of the mask for certain surgical procedures. We sent a questionnaire to all anaesthetists in Wales to discover the frequency of use of the laryngeal mask and the preferred insertion metho...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1996.tb12575.x

    authors: Dingley J,Asai T

    更新日期:1996-06-01 00:00:00

  • Vecuronium--a variable dose technique.

    abstract::Vecuronium was administered to patients in doses of 100, 150, 200 and 250 micrograms/kg and the duration of action recorded by noting the time to recovery of the first twitch in a train-of-four to 10% of the control twitch. The recovery times ranged from a mean of 28.4 minutes (100 micrograms/kg) to 72.4 minutes (250 ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1987.tb03000.x

    authors: Feldman SA,Liban JB

    更新日期:1987-02-01 00:00:00

  • Anticipated difficult airway during obstetric general anaesthesia: narrative literature review and management recommendations.

    abstract::We reviewed the literature on management of general and regional anaesthesia in pregnant women with anticipated airway difficulty. We identified 138 publications comprising 158 cases; these either described equipment or techniques for the provision of general anaesthesia, or the management of women with regional analg...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/anae.15007

    authors: Mushambi MC,Athanassoglou V,Kinsella SM

    更新日期:2020-07-01 00:00:00

  • Tracheal versus intravenous atropine. A comparison of the effects on heart rate.

    abstract::Atropine 600 micrograms was given either intravenously or intratracheally and the change in heart rate noted in a double-blind, randomised study of 40 anaesthetised patients. There was no significant difference between the two groups in the maximum increase in heart rate, 20.3 beats/minute in the tracheal compared to ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1987.tb05226.x

    authors: Bray BM,Jones HM,Grundy EM

    更新日期:1987-11-01 00:00:00

  • A randomised comparison between ultrasound and nerve stimulation for infraclavicular catheter placement.

    abstract::We conducted this study to determine if placement of infraclavicular catheters guided by ultrasound is quicker than placement guided by nerve stimulation. Infraclavicular brachial plexus catheters were inserted in 210 randomly allocated patients who were scheduled for elective hand or elbow surgery. Needle and cathete...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/anae.13302

    authors: Dhir S,Armstrong K,Armstrong P,Bouzari A,Mall J,Yu J,Ganapathy S,King G

    更新日期:2016-02-01 00:00:00

  • Detecting awareness during general anaesthetic caesarean section. An evaluation of two methods.

    abstract::Seventy-four patients received general anaesthesia for Caesarean section. Seven percent of the elective group and 28% of the emergency patients reported dreaming or recall of voices during the procedure (p less than 0.05) at postoperative interview. One patient from each group reported feeling pain or suffocation. All...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1990.tb14732.x

    authors: Bogod DG,Orton JK,Yau HM,Oh TE

    更新日期:1990-04-01 00:00:00

  • Patient-controlled analgesia--the need for caution. A case report and review of adverse incidents.

    abstract::Respiratory depression and oversedation occurred during the administration of patient-controlled analgesia because of a broken syringe barrel. Possible complications in the use of patient-controlled analgesia are reviewed. These may be because of prescription or provision errors, patient factors or equipment problems....

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.1988.tb05753.x

    authors: Thomas DW,Owen H

    更新日期:1988-09-01 00:00:00

  • Randomised double-blinded comparison of phenylephrine vs ephedrine for maintaining blood pressure during spinal anaesthesia for non-elective Caesarean section*.

    abstract:SUMMARY:In a randomised, double-blinded study, we compared boluses of phenylephrine 100 microg with ephedrine 10 mg for treating hypotension (systolic blood pressure < 100 mmHg) in 204 patients having non-elective Caesarean section under spinal anaesthesia. Umbilical arterial (UA) and venous (UV) pH and base excess wer...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2008.05635.x

    authors: Ngan Kee WD,Khaw KS,Lau TK,Ng FF,Chui K,Ng KL

    更新日期:2008-12-01 00:00:00

  • Topical lignocaine and thiopentone for the insertion of a laryngeal mask airway; a comparison with propofol.

    abstract::We assessed conditions for insertion of a laryngeal mask airway in 90 unpremedicated adult patients who received either thiopentone 5 mg.kg-1 preceded by 40 mg of topical lignocaine spray to the posterior pharyngeal wall or propofol 2.5 mg.kg-1 alone in a randomised, single-blinded trial. All patients received fentany...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1996.tb07860.x

    authors: Seavell CR,Cook TM,Cox CM

    更新日期:1996-07-01 00:00:00

  • Undiagnosed adult diastematomyelia associated with neurological symptoms following spinal anaesthesia.

    abstract::Spinal anaesthesia is a safe, routinely performed procedure. However, in patients with lumbar cutaneous abnormities or deformities of the lower extremities, a previously undetected spinal anomaly may be present. In such patients, it may be prudent to avoid central neuraxial block to prevent neural damage. This instruc...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2001.01916.x

    authors: Wenger M,Hauswirth CB,Brodhage RP

    更新日期:2001-08-01 00:00:00

  • The effect of the European Working Time Directive on anaesthetic working patterns and training.

    abstract::There is concern that the European Working Time Directive 2009 has led to reduced time available for training, and this study examined if this has been the case. For two identical six-month periods in 1999 (pre-Directive) and 2009 (post-Directive), weekly data were collected on the total number of sessions attended by...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2012.07227.x

    authors: Paul RG,Bunker N,Fauvel NJ,Cox M

    更新日期:2012-09-01 00:00:00

  • Comparison of bladder, oesophageal and pulmonary artery temperatures in major abdominal surgery.

    abstract::In this study we compared urinary bladder and oesophageal temperatures with the core temperature obtained from a pulmonary artery catheter in patients undergoing orthotopic liver transplantation. The bladder temperature was a closer approximation to pulmonary artery temperature in this group of patients than the oesop...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1365-2044.1996.tb07743.x

    authors: Russell SH,Freeman JW

    更新日期:1996-04-01 00:00:00

  • Facial signs of respiratory distress after cardiac surgery. A plea for the clinical approach to mechanical ventilation.

    abstract::The face is a rich source of information about the respiratory, cardiovascular and neurological state of the patient. These systems are particularly affected in the adult respiratory distress syndrome (ARDS) after cardiac surgery. It is possible to make firm decisions about mechanical ventilation by scrupulously caref...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1976.tb12332.x

    authors: Gilston A

    更新日期:1976-04-01 00:00:00

  • Anaesthesia for a patient with carcinoid syndrome.

    abstract::Anaesthesia for abdominal surgery in a patient with carcinoid syndrome is reported. Pre-operative symptomatic improvement was obtained using cyproheptadine hydrochloride. Handling of the tumour and liver metastases, during surgery, produced signs of excess serotonin secretion which responded to intravenous methotrimep...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1976.tb11797.x

    authors: Mason RA,Steane PA

    更新日期:1976-03-01 00:00:00

  • A simulation-based evaluation of two proposed alternatives to Luer devices for use in neuraxial anaesthesia.

    abstract::The National Patient Safety Agency has issued a Patient Safety Alert with the aim of eliminating Luer connectors from equipment for lumbar puncture and subarachnoid injections by 1 April 2011, and from all neuraxial and regional anaesthesia equipment in 2013. B-link (UK) Ltd and InterVene Ltd have produced non-Luer co...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2010.06537.x

    authors: Cook TM,Payne S,Skryabina E,Hurford D,Clow E,Georgiou A

    更新日期:2010-11-01 00:00:00

  • Haemostatic management of obstetric haemorrhage.

    abstract::The haemostatic management of major obstetric haemorrhage remains challenging, and current published guidance relies heavily on experience from the non-pregnant population and expert opinion. In recent years, an interest in the implications of relative hypofibrinogenaemia, point-of-care monitoring of coagulation abnor...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/anae.12913

    authors: Collis RE,Collins PW

    更新日期:2015-01-01 00:00:00

  • Decision analysis in anaesthesia: a tool for developing and analysing clinical management plans.

    abstract::Traditional medical decision making is unstructured and incorporates evidence haphazardly. I present a more structured approach based on decision analysis, a model that considers all relevant options and outcomes informed by evidence where appropriate. This method is useful both for planning clinical management and fo...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.2006.04649.x

    authors: Yentis SM

    更新日期:2006-07-01 00:00:00

  • The effect of a heat and moisture exchanger on gas flow in a Mapleson F breathing system during inhalational induction.

    abstract::Heat and moisture exchangers (HMEs) humidify, warm and filter inspired gas, protecting patients and apparatus during anaesthesia. Their incorporation into paediatric anaesthetic breathing systems is recommended. We experienced delays in inhalational induction whilst using a Mapleson F breathing system with an HME. We ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2000.01521.x

    authors: Da Fonseca JM,Wheeler DW,Pook JA

    更新日期:2000-06-01 00:00:00

  • Obstetric anaesthetists' workload.

    abstract::The current recommendation of one consultant session per 500 deliveries with full sessional cover for units over 3000 deliveries is arbitrary and is not based on workload. The Audit Commission has questioned the wide variability of anaesthetic staffing on labour wards. The aim of this study was to investigate whether ...

    journal_title:Anaesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1046/j.0003-2409.2001.02402.x

    authors: Wee MY,Yentis SM,Thomas P

    更新日期:2002-05-01 00:00:00

  • Continuous display of plasma potassium during cardiac surgery.

    abstract::We have evaluated the use of an intravascular ion-selective electrode for continuous plasma potassium monitoring in patients during and after cardiac surgery. Potassium estimations from the indwelling electrode provided a rapid and sensitive, but only moderately reliable, indicator of potassium as confirmed by blood s...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1987.tb02940.x

    authors: Drake HF,Treasure T,Smith B

    更新日期:1987-01-01 00:00:00

  • Estimated costs before, during and after the introduction of the emergency laparotomy pathway quality improvement care (ELPQuIC) bundle.

    abstract::Implementation of a quality improvement bundle for peri-operative management of emergency laparotomy (ELPQuIC) improved mortality in a previous study. We used data from one site that participated in that study to examine whether it was associated with the cost of care. We collected data from 396 patients: 144 before, ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.13623

    authors: Eveleigh MO,Howes TE,Peden CJ,Cook TM

    更新日期:2016-11-01 00:00:00

  • Pain on injection of propofol.

    abstract::Pain on injection of propofol is a common problem, the cause of which remains unknown. The chemical properties and preparation of propofol, proposed mechanisms for the cause of the pain and clinical strategies to prevent pain on injection of propofol are reviewed in the hope of shedding some light on the subject. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2044.1998.00405.x

    authors: Tan CH,Onsiong MK

    更新日期:1998-05-01 00:00:00

  • The effect of pre-induction glycopyrronium on the haemodynamic response of elderly patients to anaesthesia with propofol.

    abstract::This study investigated whether pretreatment with glycopyrronium can attenuate the hypotension caused by anaesthesia of the elderly with propofol. Twenty elderly patients (77.1 +/- 2.44 years, mean +/- SEM) of ASA physical status 2 or 3 scheduled for elective urological procedures were given glycopyrronium 0 (n = 10) ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1992.tb02341.x

    authors: Sneyd JR,Mayall R

    更新日期:1992-07-01 00:00:00

  • Acid aspiration prophylaxis for emergency Caesarean section.

    abstract::Over a 3.5 year period, 384 patients requiring emergency Caesarean section under general anaesthesia received at random one of six acid aspiration prophylaxis regimens as soon as the decision was made for surgery. In the first phase of the study, sodium citrate administered orally 0.3 M, 30 ml (group C, n = 120) was c...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1996.tb07782.x

    authors: Stuart JC,Kan AF,Rowbottom SJ,Yau G,Gin T

    更新日期:1996-05-01 00:00:00