Picotamide, a combined inhibitor of thromboxane A2 synthase and receptor, reduces 2-year mortality in diabetics with peripheral arterial disease: the DAVID study.

abstract：:Contraceptive counselling should begin early in females with heart disease, preferably directly after the start of menstruation. In coming to a decision about the method of contraception, the following issues should be considered: (i) the risk of pregnancy for the mother and the consequences of an unplanned pregnancy;...

journal_title：European heart journal

authors： Roos-Hesselink JW,Cornette J,Sliwa K,Pieper PG,Veldtman GR,Johnson MR

更新日期：2015-07-14 00:00:00

abstract：AIM:To evaluate the effect of alirocumab on frequency of standard apheresis treatments [weekly or every 2 weeks (Q2W)] in heterozygous familial hypercholesterolaemia (HeFH). METHODS AND RESULTS:ODYSSEY ESCAPE (NCT02326220) was a double-blind study in 62 HeFH patients undergoing regular weekly or Q2W lipoprotein aphere...

journal_title：European heart journal

authors： Moriarty PM,Parhofer KG,Babirak SP,Cornier MA,Duell PB,Hohenstein B,Leebmann J,Ramlow W,Schettler V,Simha V,Steinhagen-Thiessen E,Thompson PD,Vogt A,von Stritzky B,Du Y,Manvelian G

更新日期：2016-12-21 00:00:00

abstract：AIMS:Elevated blood pressure (EBP) is the most prevalent and potentially modifiable risk factor for AF, yet little is known of its atrial effects. We aimed to characterize the atrial electrical and structural changes in a chronic ovine model of EBP after prenatal corticosteroid exposure. METHODS AND RESULTS:Twelve she...

journal_title：European heart journal

authors： Kistler PM,Sanders P,Dodic M,Spence SJ,Samuel CS,Zhao C,Charles JA,Edwards GA,Kalman JM

更新日期：2006-12-01 00:00:00

abstract：:The author reviews statistical methods commonly applied in economic evaluations that rely on individual patient-level data. The paper includes a review of foundational concepts, unique characteristics of health economic data, and methods developed to address them. The paper then highlights issues that should be consid...

journal_title：European heart journal

authors： Reed SD

更新日期：2014-07-01 00:00:00

abstract：:In myocarditis an antigen-specific immune response to cardiac epitopes has been demonstrated by several investigators. In 25 patients with histologically proven myocarditis, autoantibodies to cardiac tissue were observed in 65% by immunofluorescence assay. By immunoblot analysis 46% of sera reacted with cardiac tissue...

journal_title：European heart journal

authors： Pankuweit S,Lottspeich F,Maisch B

更新日期：1995-12-01 00:00:00

abstract：:Impaired coronary reserve and increased minimal coronary resistance have been documented in several animal models of left ventricular hypertrophy. There is controversy whether the increased minimal coronary resistance is due to vascular or extravascular causes. To test the hypothesis that pressure-overloaded left vent...

journal_title：European heart journal

authors： O'Gorman DJ,Thomas P,Turner MA,Sheridan DJ

更新日期：1992-05-01 00:00:00

abstract：:Valvular heart disease is a significant, global cause of morbidity and mortality. In the ageing population of industrialized nations, degenerative aortic stenosis has become the most common native valve disorder. Although surgical aortic valve replacement is associated with excellent clinical outcomes, a large number ...

journal_title：European heart journal

authors： Schoenhagen P,Tuzcu EM,Kapadia SR,Desai MY,Svensson LG

更新日期：2009-09-01 00:00:00

abstract：:Myocardial dyssynergy does not necessarily indicate myocardial necrosis in patients with coronary artery disease. The differentiation between viable and non-viable tissue is of great clinical importance in order to make the most appropriate clinical decision in the individual patient. Several techniques are used to as...

journal_title：European heart journal

authors： Piérard LA,Lancellotti P,Benoit T

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Myocardial ischaemia occurs principally in the subendocardial layer, whereas conventional myocardial perfusion imaging provides no information on the transmural myocardial blood flow (MBF) distribution. Subendocardial perfusion measurements and quantification of the transmural perfusion gradient (TPG) could ...

journal_title：European heart journal

authors： Danad I,Raijmakers PG,Harms HJ,Heymans MW,van Royen N,Lubberink M,Boellaard R,van Rossum AC,Lammertsma AA,Knaapen P

更新日期：2014-08-14 00:00:00

abstract：AIMS:Aspirin combined with clopidogrel is the treatment of choice for acute coronary syndromes. Although the maintenance of aspirin until surgery does not affect postoperative bleeding after coronary artery bypass graft (CABG) surgery, the latter may be dramatically increased when clopidogrel is continued over a period...

journal_title：European heart journal

authors： Ouattara A,Bouzguenda H,Le Manach Y,Léger P,Mercadier A,Leprince P,Bonnet N,Montalescot G,Riou B,Coriat P

更新日期：2007-04-01 00:00:00

abstract：AIMS:Here, the aim is to assess long-term clinical variation (CV) of N-terminal pro-brain natriuretic peptide (NT-proBNP) in stable chronic heart failure (CHF) patients. The proposed use of NT-proBNP for monitoring of CHF patients will require accurate information about long-term CV of the peptide. METHODS AND RESULTS...

journal_title：European heart journal

authors： Schou M,Gustafsson F,Kjaer A,Hildebrandt PR

更新日期：2007-01-01 00:00:00

abstract：:Impaired left ventricular (LV) filling is known to be a major determinant of non-obstructive hypertrophic cardiomyopathy (HCM). Seventeen patients with non-obstructive HCM (mean age 71 years) were investigated by Doppler echocardiography, before and after oral treatment with verapamil (mean daily doses: 335 mg). Diagn...

journal_title：European heart journal

authors： Friart A,Stamatakis L,Philippart C

更新日期：1990-09-01 00:00:00

abstract：AIMS:Our aim was to follow changes in myocardial function and physiology in patients awaiting coronary artery bypass surgery (CABG) and relate changes to post-revascularisation functional response. METHODS AND RESULTS:In 21 patients with CAD and LV dysfunction, myocardial glucose utilisation (MGU) and blood flow (MBF)...

journal_title：European heart journal

authors： Pitt M,Dutka D,Pagano D,Camici P,Bonser R

更新日期：2004-03-01 00:00:00

abstract：AIMS:Whether the association between fibrinogen and cardiovascular events reflects an association with advanced atherosclerosis in general, or rupture-prone plaques in particular, is unclear. We examined whether fibrinogen predicts incidence of ischaemic stroke, advanced atherosclerosis (measured as carotid artery sten...

journal_title：European heart journal

authors： Kofoed SC,Wittrup HH,Sillesen H,Nordestgaard BG

更新日期：2003-03-01 00:00:00

abstract：:Hereditary factors may have a part to play in the development of bicuspid aortic valve. This report concerns a pair of identical twins, probably monozygotic, who required aortic valve replacement as a result of aortic stenosis occurring in bicuspid aortic valves. This supports the contention that there may be a geneti...

journal_title：European heart journal

authors： Godden DJ,Sandhu PS,Kerr F

更新日期：1987-03-01 00:00:00

abstract：AIMS:Treatment of atrial fibrillation remains a major clinical challenge owing to the limited efficacy and safety of anti-arrhythmic drugs, particularly in patients with structural heart disease. METHODS AND RESULTS:To evaluate the efficacy of azimilide, a new class III anti-arrhythmic drug, we studied 658 patients wi...

journal_title：European heart journal

authors： Lombardi F,Borggrefe M,Ruzyllo W,Lüderitz B,A-COMET-II Investigators.

更新日期：2006-09-01 00:00:00

abstract：AIMS:To evaluate the association between occupational and leisure-time physical activity (PA), ownership of goods promoting sedentary behaviour, and the risk of myocardial infarction (MI) in different socio-economic populations of the world. Studies in developed countries have found low PA as a risk factor for cardiova...

journal_title：European heart journal

authors： Held C,Iqbal R,Lear SA,Rosengren A,Islam S,Mathew J,Yusuf S

更新日期：2012-02-01 00:00:00

abstract：:Brief hyperventilation is occasionally accompanied by repolarization abnormalities in subjects without apparent heart disease. However, the effect of prolonged hyperventilation on repolarization abnormalities is not clearly defined. We analysed the repolarization abnormalities induced by prolonged hyperventilation, co...

journal_title：European heart journal

authors： Alexopoulos D,Christodoulou J,Toulgaridis T,Sitafidis G,Manias O,Hahalis G,Vagenakis AG

更新日期：1996-09-01 00:00:00

abstract：:Sequential alterations of left ventricular volumes and haemodynamics were studied in 29 patients between 4 days and 4 weeks after myocardial infarction. Left ventricular volume was determined by single photon emission computerized tomography (SPECT), infarct size by creatine kinase (CK) analysis, angiography and thall...

journal_title：European heart journal

authors： Gaudron P,Eilles C,Ertl G,Kochsiek K

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Patients with univentricular hearts have decreased exercise tolerance and may demonstrate exertional dyspnoea. It is not known if chronic hypoxaemia exacerbates exercise intolerance and contributes to symptomatic limitation. The extent to which surgical correction of a right-to-left shunt by a Fontan-type pr...

journal_title：European heart journal

authors： Iserin L,Chua TP,Chambers J,Coats AJ,Somerville J

更新日期：1997-08-01 00:00:00

abstract：:Eight young healthy male subjects, members of a Himalayan expedition, underwent 24 h Holter monitoring before departure, after 1 and 4 weeks at high altitude (5000 m) and after return to sea level. At high altitude, the circadian reciprocal changes in low and high frequency (LF, HF) were absent, with no significant re...

journal_title：European heart journal

authors： Ponchia A,Noventa D,Bertaglia M,Carretta R,Zaccaria M,Miraglia G,Pascotto P,Buja G

更新日期：1994-11-01 00:00:00

abstract：:A possibility that can be advanced to explain the antihypertensive effect of beta-blocking drugs is that they act through the baroreflex control of the cardiovascular system. In 38 essential hypertensive patients we measured 1) The lengthening and shortening in R-R interval caused by stimulation or deactivation of art...

journal_title：European heart journal

authors： Parati G,Pomidossi G,Grassi G,Gavazzi C,Ramirez A,Gregorini L,Mancia G

更新日期：1983-07-01 00:00:00

abstract：AIMS:To analyse the relationship between initial exercise parameters and peak oxygen consumption and prognosis in 96 patients with congestive heart failure. METHODS AND RESULTS:Comparison of responses during the initial 6 min of cardiopulmonary exercise testing (Naughton modified protocol) in patients stratified to th...

journal_title：European heart journal

authors： de Vries RJ,van Veldhuisen DJ,Dunselman PH,van der Veer N,Crijns HJ

更新日期：1997-12-01 00:00:00

abstract：AIMS:Although cerebral blood flow (CBF) is known to be low in patients with advanced systolic heart failure (HF), little is known of the prognostic significance of this observation. We investigated whether CBF might be associated with the development of adverse outcomes in systolic HF, and whether it might provide prog...

journal_title：European heart journal

authors： Kim MS,Kim JS,Yun SC,Lee CW,Song JK,Park SW,Park SJ,Kim JJ

更新日期：2012-02-01 00:00:00

abstract：:The implementation of molecular biological approaches has led to the discovery of single genetic variations that contribute to the development of cardiac failure. In the present review, the characteristics that are invariably associated with the development of failure in experimental animals and clinical studies are d...

journal_title：European heart journal

authors： Lips DJ,deWindt LJ,van Kraaij DJ,Doevendans PA

更新日期：2003-05-01 00:00:00

abstract：:The effects of dexamethasone on cultured rat beating heart cells experimentally infected with coxsackievirus B2 were investigated at an early stage (1-3 days) post challenge. Changes in the release of the cardiac enzyme, aspartate amino-transferase (AST), beating %, cytopathic effect (CPE), virus titre, ultrastructure...

journal_title：European heart journal

authors： Yang YZ,Yuan WL,Guo Q,Gong ZX,Zhow TS,Shen JY,Chen HZ

更新日期：1991-08-01 00:00:00

abstract：:The clinical value of QRST isointegral maps (I-maps) for the detection of myocardial infarction (MI) in the presence of left bundle branch block (LBBB) was investigated. We recorded I-maps during sinus rhythm and right ventricular (RV) pacing, which simulated LBBB, in 62 patients with MI (42 patients had at least one ...

journal_title：European heart journal

authors： Suzuki A,Hirai M,Hayashi H,Tomita Y,Ichihara Y,Adachi M,Oguchi S,Takatsu F

更新日期：1993-08-01 00:00:00

abstract：:A right atrial myxoma was detected by cross-sectional echocardiography in a 21-year-old woman with cutaneous lentiginosis. The lentigines were present mainly on the right side of the trunk. ...

journal_title：European heart journal

authors： Göksel S,Kural T

更新日期：1989-08-01 00:00:00

abstract：:The prevalence of coronary heart disease (CHD) was determined in a general population sample of 9141 Icelandic men aged 34-79 years, and the prevalence of four different forms of CHD was estimated separately: symptomatic infarction fulfilling WHO-MONICA criteria for definite myocardial infarction; myocardial infarctio...

journal_title：European heart journal

authors： Sigurdsson E,Thorgeirsson G,Sigvaldason H,Sigfusson N

更新日期：1993-05-01 00:00:00

abstract：:Re-entry was demonstrated as a self-perpetuating mechanism as early as 1906. It may lead to single-cycle electrocardiographic phenomena as well as reciprocating tachycardias. Factors favouring re-entry are as follows. Unidirectional or temporary local block of conduction, a mechanism always involved in initiation of r...

journal_title：European heart journal

authors： Olsson SB

更新日期：1984-09-01 00:00:00