Abstract:
OBJECTIVES:Increased lung uptake of thallium-201 in exercise myocardial perfusion imaging is a reliable marker of multivessel disease in patients with ischemic heart disease. This study investigated whether the lung-to-heart uptake ratio with techenetium-99m(99mTc)-tetrofosmin also provides valuable information to detect patients with multivessel disease. METHODS:Fifty-three consecutive patients (35 men, 18 women, mean age 66 +/- 11 years; single-vessel disease: 29, double-vessel disease: 16, triple-vessel disease: 8) with stable effort angina pectoris without prior myocardial infarction and 17 control subjects (12 men, 5 women, mean age 62 +/- 9 years) underwent exercise myocardial perfusion imaging with 99mTc-tetrofosmin and coronary angiography in January 2000 to December 2002. The lung-to-heart uptake ratio was calculated on an anterior projection before reconstruction of the exercise single photon emission computed tomographic images. RESULTS:The mean lung-to-heart uptake ratio was 0.34 +/- 0.04, 0.38 +/- 0.07, 0.41 +/- 0.05, and 0.46 +/- 0.09, in patients with normal coronary, single-vessel disease, double-vessel disease, and triple-vessel disease, respectively. Significantly higher lung-to-heart uptake ratio was associated with more diseased vessels (p < 0.05). Multivessel disease could be detected with a sensitivity of 67% and a specificity of 74% if the cut-off point of the lung-to-heart uptake ratio was set as 0.4. Combining lung-to-heart uptake ratio with conventional myocardial perfusion imaging improved the sensitivity to detect multivessel disease to 83% and the specificity to 74%. CONCLUSIONS:Lung-to-heart uptake ratio measured by exercise myocardial scintigraphy with 99mTc-tetrofosmin can provide clinically useful information to detect multivessel disease in patients with ischemic heart disease.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Okajima T,Ueshima K,Nishiyama O,Ogawa M,Ohuchi M,Saitoh M,Hiramori Ksubject
Has Abstractpub_date
2004-04-01 00:00:00pages
165-71issue
4eissn
0914-5087issn
1876-4738journal_volume
43pub_type
杂志文章abstract:OBJECTIVES:The feasibility of detecting persistent regional left ventricular abnormal relaxation due to myocardial ischemia using strain echocardiography several minutes after exercise was investigated. METHODS:Consecutive 27 patients (mean age 65 +/- 9 years, 21 males, 6 females) with suspected coronary artery diseas...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2006-04-01 00:00:00
abstract::In patients with right ventricular overload, the free wall of the right ventricle is often visualized by 201T1 myocardial scintigraphy. To determine quantitatively the discriminant and characteristics of cor pulmonale, 201T1 myocardial perfusion single photon emission computed tomography (SPECT) was performed in 16 pa...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::To investigate which time constant of isovolumic left ventricular pressure (LVP) decay is the most sensitive measure in acute myocardial ischemia, the time constant of isovolumic relaxation (IR) was calculated by two different models, the semilogarithmic model assuming a zero of LVP decline (TL) and an exponential mod...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:To evaluate whether balloon inflation for post-dilatation causes longitudinal stent deformation (LSD). METHODS AND RESULTS:Two stents, sized 2.5mm×28mm and 3.5mm×28mm (Nobori®, biodegradable polymer biolimus-eluting stent; Ultimaster®, biodegradable polymer sirolimus-eluting stent; Terumo Co., Tokyo, Japan)...
journal_title:Journal of cardiology
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pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::A 55-year-old man was admitted to our hospital complaining of dyspnea and chest pain. Transthoracic echocardiography showed dilation of the right ventricle. Chest computed tomography with contrast medium showed multiple emboli in the pulmonary arteries. Venography of the lower extremities showed multiple thrombi in th...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2001-10-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.jjcc.2012.06.006
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pub_type: 杂志文章
doi:10.1016/j.jjcc.2014.12.010
更新日期:2015-10-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.jjcc.2011.07.009
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pub_type: 杂志文章
doi:10.1016/j.jjcc.2016.07.008
更新日期:2017-01-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:
更新日期:2000-03-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::Two patients presented with transient left ventricular apical ballooning (takotsubo cardiomyopathy) induced by emotional stress caused by the Central Niigata Prefecture Earthquake in 2004. These patients complained of chest pain immediately after the earthquake. In patient 1, electrocardiography (ECG) showed slight ST...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::We examined the clinical characteristics and electrocardiographic findings of 7 patients having the acquired long QT syndrome who developed torsades de pointes while receiving no antiarrhythmic drugs. A total of 43 episodes of torsades de pointes were documented among these patients. Underlying heart diseases were pre...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:Paroxysmal nocturnal dyspnea (PND) is a common symptom for patients with acute decompensated heart failure (ADHF). Some symptoms of PND are similar to those of sleep apnea (SA) which might be associated with overnight worsening hemodynamics in failing hearts. However, the association between PND, SA, and ove...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2012.12.010
更新日期:2013-05-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2015.05.014
更新日期:2016-03-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2001-08-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2008.11.013
更新日期:2009-10-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jjcc.2019.01.007
更新日期:2019-08-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Ischemic preconditioning is an attenuation of myocardial ischemia by repeated brief coronary occlusions observed during percutaneous transluminal coronary angioplasty (PTCA). The effects of the time delay between balloon inflations during PTCA on ischemic preconditioning were investigated in 48 patients with chronic s...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::The precipitating factors of repetitive exacerbation were investigated in 110 consecutive patients with chronic left heart failure admitted due to acute exacerbation more than twice to the medical emergency ward of National Cardiovascular Center from January, 1992 to December, 1996. The controls were 189 consecutive p...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.04.013
更新日期:2019-11-01 00:00:00
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journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
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