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Impact of post-dilatation on longitudinal stent elongation: An in vitro study.

Abstract：

OBJECTIVES:To evaluate whether balloon inflation for post-dilatation causes longitudinal stent deformation (LSD). METHODS AND RESULTS:Two stents, sized 2.5mm×28mm and 3.5mm×28mm (Nobori®, biodegradable polymer biolimus-eluting stent; Ultimaster®, biodegradable polymer sirolimus-eluting stent; Terumo Co., Tokyo, Japan), were deployed at nominal pressure in straight and tapered silicon vessel models. Then, post-dilatation was performed in two ways: dilatation from the distal (D-P group) or proximal (P-D group) side of the stent. Microscopic findings showed that the stents were elongated during every step of the procedure regardless of the post-dilatation method and type of vessel model. The D-P group showed linear elongation during each step of post-dilatation (straight model: 28.7±0.3mm vs. 29.9±0.3mm, p=0.002; tapered model: 28.0±0.1mm vs. 29.9±0.1mm, p<0.001). In contrast, in the P-D group, the most significant change was observed in the first step of post-dilatation and only slight changes were observed thereafter (straight model: 28.6±0.1mm vs. 29.5±0.1mm, p<0.001; tapered model: 28.2±0.1mm vs. 29.5±0.1mm, p<0.001). Optical frequency domain imaging analysis showed that the frequency of stent strut malapposition was positively correlated with the percentage change in stent length (r=0.74, p<0.0001). CONCLUSION:LSD was observed during every step of post-dilatation in both the straight and tapered vessel models. However, some differences were observed between the D-P and P-D groups. Minimizing stent strut malapposition may reduce the risk of LSD.

journal_name

J Cardiol

journal_title

Journal of cardiology

authors

Sumi T,Ishii H,Tanaka A,Suzuki S,Kojima H,Iwakawa N,Aoki T,Hirayama K,Mitsuda T,Harada K,Negishi Y,Ota T,Kada K,Murohara T

doi

10.1016/j.jjcc.2017.11.003

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

464-470

issue

5

eissn

0914-5087

issn

1876-4738

pii

S0914-5087(17)30319-2

journal_volume

71

pub_type

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