Abstract：
:Cirrhotic patients admitted to the medical intensive care unit (ICU) are associated with high mortality rates. The prognosis of critically ill cirrhotic patients is determined by the extent of hepatic and extrahepatic organ dysfunction. This study was conducted to assess and compare the accuracy of the Child-Pugh classification and APACHE II scores, obtained on the first day of ICU admission, in predicting hospital mortality in critically ill cirrhotic patients. One hundred thirty-five patients diagnosed with liver cirrhosis were admitted to the medical ICU between January 2002 and March 2003. Information considered necessary to compute the Child-Pugh and APACHE II scores on the first day of ICU admission was prospectively collected. The overall hospital mortality rate was 66.6%. Liver disease was most commonly attributed to hepatitis B viral infection. The APACHE II scores demonstrate a good fit using the Hosmer and Lemeshow goodness-of-fit test. Furthermore, by using the areas under receiver operating characteristic (AUROC) curve, the APACHE II scores demonstrated a better discriminative power (AUROC 0.833 +/- 0.039) than Child-Pugh scores (AUROC 0.75 +/- 0.05) (P=.024). This investigation confirms the grave prognosis for the cirrhotic patients admitted to the ICU. While both Child-Pugh and the APACHE II scores can satisfactorily predict the outcomes for critically ill cirrhotic patients, APACHE II is more powerful in discriminating the survivors from the nonsurvivors.
journal_name
J Intensive Care Medjournal_title
Journal of intensive care medicineauthors
Ho YP,Chen YC,Yang C,Lien JM,Chu YY,Fang JT,Chiu CT,Chen PC,Tsai MHdoi
10.1177/0885066603261991subject
Has Abstractpub_date
2004-03-01 00:00:00pages
105-10issue
2eissn
0885-0666issn
1525-1489journal_volume
19pub_type
杂志文章abstract：:Intravascular volume status and volume responsiveness continue to be important questions for the management of critically ill or injured patients. Goal-directed hemodynamic therapy has been shown to be of benefit to patients with severe sepsis and septic shock, acute lung injury and adult respiratory distress syndrome...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066609344908
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:Morbidity associated with stress ulcer-related bleeding, the cost of medications, and the possible complications associated with stress ulcer prophylaxis are important considerations when prescribing prophylaxis. We prospectively studied the prescription patterns for stress ulcer prophylaxis in patients admi...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,多中心研究
doi：10.1177/0885066612453542
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND::While indirect calorimetry (IC) is the gold standard used to calculate specific calorie needs in the critically ill, predictive equations are frequently utilized at many institutions for various reasons. Prior studies suggest these equations frequently misjudge actual resting energy expenditure (REE) in med...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066617702077
更新日期：2019-05-01 00:00:00
abstract：:Heparin-induced thrombocytopenia requires immediate alternative anticoagulation to prevent or treat thromboembolic complications. Argatroban was approved based on multiple-center studies from the 1990s, but subsequent changes in prevailing awareness, diagnostic testing and therapeutic strategies for heparin-induced th...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066605284590
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:Acupuncture treatment has been employed in China for over 2500 years and it is used worldwide as analgesia in acute and chronic pain. Acupuncture is also used in general anesthesia (GA). The aim of this systematic review and meta-analysis was to assess the efficacy of electroacupuncture (EA) in addition to G...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,meta分析
doi：10.1177/0885066617708558
更新日期：2019-08-01 00:00:00
abstract：:Longitudinal clivus fractures are rare in children, with only 5 cases published in the English literature to date. Clivus fractures, particularly longitudinal type, are associated with high mortality and morbidity. We report a case of longitudinal clivus fracture in a teenager with survival and complete neurological r...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066614555481
更新日期：2015-10-01 00:00:00
abstract：:Periodic epileptiform discharges (PEDs) are frequently encountered during continuous electroencephalography monitoring in the intensive care unit. Their implications and management are variable and highly dependent on the clinical context. This article is intended for the nonneurologist intensivist, reviews basic term...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066613513411
更新日期：2015-10-01 00:00:00
abstract：:The aim of the study was to describe our experience with bi-level positive airway pressure (BiPAP) ventilation in oncology children with acute respiratory failure, hospitalized in a single tertiary pediatric tertiary center. This was a retrospective cohort study of all pediatric oncology patients in our center admitte...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066609344956
更新日期：2009-11-01 00:00:00
abstract：:Extracorporeal membrane oxygenation (ECMO) comprises a commonly used method of extracorporeal life support. It has proven efficacy and is an accepted modality of care for isolated respiratory or cardiopulmonary failure in neonatal and pediatric populations. In adults, there are conflicting studies regarding its benefi...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066610384061
更新日期：2011-01-01 00:00:00
abstract：:The role of percutaneous transluminal coronary angioplasty (PTCA) in the management of acute myocardial infarction (AMI) has not yet been precisely defined. The longest experience with PTCA in this setting has been in patients who are not candidates for thrombolytic therapy and in patients in whom thrombolysis has fai...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/088506669501000402
更新日期：1995-07-01 00:00:00
abstract：BACKGROUND:Isolated shortness of breath in the patient with a history of a malignancy creates a diagnostic challenge and serves as a source of anxiety. Although cancer recurrence is typically the first concern of the patient and the clinician, toxicities of anticancer therapies must also be considered. METHODS:A case ...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066614538910
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND::Patients with septic shock by multidrug resistant (MDR) microorganism maybe considered a specific population of critical patients at very high risk of death in whom the effects of standard sepsis treatment has never been assessed. The objective of this retrospective analysis was to evaluate the risk factors...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066616688165
更新日期：2019-01-01 00:00:00
abstract：:Patients undergoing surgery for pituitary tumors represent a heterogeneous population each with unique clinical, biochemical, radiologic, pathologic, neurologic, and/or ophthalmologic considerations. The postoperative management of patients following pituitary surgery often occurs in the context of a dynamic state of ...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066605275247
更新日期：2005-05-01 00:00:00
abstract：:Aspergillus fumigatus hyphae is often found in the lung tissue of patients with bronchocentric granulomatosis (BCG). This organism is believed to be one agent responsible for inciting the hypersensitivity response and subsequent development of the characteristic pathology that defines BCG. The definitive etiology of t...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/088506669501000106
更新日期：1995-01-01 00:00:00
abstract：:Antibacterial resistance is increasing throughout the world, while the development of new agents is slowly progressing. In addition, the increasing prevalence of fluoroquinolone resistance may force many practitioners to choose an aminoglycoside agent in gram-negative regimens. Aminoglycosides are bactericidal agents ...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066610377968
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:Pharmacogenomic (PGx) testing has the potential to provide information on specific drug-metabolizing enzymes that may lead to an absence, reduction, or increase in medication effect in patients. There is a paucity of prospective studies examining PGx testing in the intensive care unit (ICU) setting. RESEARC...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066620946303
更新日期：2020-07-31 00:00:00
abstract：:Although the number of available donor hearts severely limits the epidemiologic impact of heart transplantation on patients with heart failure, patients with end-stage heart failure unresponsive to medical management currently have no other viable alternatives. Destination therapy with a ventricular assist device is t...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066603259012
更新日期：2004-01-01 00:00:00
abstract：:Thyroid storm, an endocrine emergency first described in 1926, remains a diagnostic and therapeutic challenge. No laboratory abnormalities are specific to thyroid storm, and the available scoring system is based on the clinical criteria. The exact mechanisms underlying the development of thyroid storm from uncomplicat...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066613498053
更新日期：2015-03-01 00:00:00
abstract：:Despite an overall decline in the incidence of tuberculosis (TB), the percentage of cases representing miliary TB has remained stable. We report 2 cases of fatal miliary TB that remained unrecognized until autopsy, occurring within a 6-month period at 1 Detroit institution. These cases represent the wide range of pres...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066605279150
更新日期：2005-11-01 00:00:00
abstract：:Bladder pressure measurement through a foley catheter is the current standard in monitoring for intraabdominal hypertension (IAH) and abdominal compartment syndrome (ACS). Accurate pressure transduction requires a continuous fluid column with a small volume of transducing medium at the tip of the catheter. Infusing ex...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066609335730
更新日期：2009-07-01 00:00:00
abstract：:The authors retrospectively review their experience with low immunoglobulin G (IgG) levels in a pediatric ICU population over a 12-month period. The total IgG level was below the normal for age in 14 of the 20 patients. The 14 patients with a low IgG level were younger and weighed less when compared with the 6 patient...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066603255905
更新日期：2003-09-01 00:00:00
abstract：:Bronchopulmonary dysplasia is the most common morbidity among surviving premature infants. Injury to the developing lung is the result of the interaction between a susceptible host and a number of contributing factors such as mechanical ventilation and infection. The resulting persistent impairment of pulmonary functi...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066604273494
更新日期：2005-03-01 00:00:00
abstract：:Acute brain injury (ABI) increases morbidity and mortality in patients with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Optimal neurologic monitoring methods have not been well-explicated. We studied the use of Near-infrared Spectroscopy (NIRS) to monitor cerebral regional oxygenation tissue saturatio...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066620966962
更新日期：2020-10-15 00:00:00
abstract：PURPOSE:Reintubation following unplanned extubation (UE) is often required and associated with increased morbidity; however, knowledge of risk factors leading to reintubation and subsequent outcomes in children is still lacking. We sought to determine the incidence, risk factors, and outcomes related to reintubation af...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066616675130
更新日期：2018-08-01 00:00:00
abstract：RATIONALE:The feasibility and clinical outcomes of conservative fluid management after sepsis resuscitation remain unknown. OBJECTIVES:To evaluate the effect of a conservative fluid management protocol on fluid balance and intensive care unit (ICU)-free days among patients with sepsis. METHODS:In a single-center phas...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066618823183
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:The aim of this study was to check if serum lactate was independently associated with mortality among critically ill patients. MATERIALS AND METHODS:This was a single-center, retrospective cohort study. All adult patients (>18 years of age) who had at least 1 measurement of lactate within 24 hours of admission...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066619854355
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Sepsis and sepsis-associated encephalopathy (SAE) are common intensive care unit (ICU) diseases; the morbidity and mortality are high. The present study analyzed the sensitivity of different diagnostic criteria of sepsis 1.0 and 3.0, epidemiological characteristics of sepsis and SAE, and explored its risk fa...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066617719750
更新日期：2019-11-01 00:00:00
abstract：:Frontal chest radiographs are the principal diagnostic imaging study to detect, verify, or exclude acute thoracic injury after trauma, and they should be obtained as quickly as possible without compromising clinical assessment and resuscitation. Chest radiographs provide important information about potentially life-th...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/088506669400900403
更新日期：1994-07-01 00:00:00
abstract：:A systematic review of the literature was conducted to determine if the administration of methylene blue in humans improves hemodynamic status and/or outcome in patients with septic shock. Studies were identified from MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials database. The review included...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章,评审
doi：10.1177/0885066606290671
更新日期：2006-11-01 00:00:00
abstract：INTRODUCTION:Emergence of multidrug-resistant (MDR) gram-negative (GN) pathogens and lack of novel antibiotics have increased the use of colistin, despite unknown optimal dosing. This study aimed to evaluate the safety and efficacy of a colistin loading dose, high-dose (LDHD) maintenance regimen in patients with MDR-GN...
journal_title：Journal of intensive care medicine
pub_type： 杂志文章
doi：10.1177/0885066616646551
更新日期：2017-09-01 00:00:00
