Abstract:
OBJECTIVE:This study was performed to assess whether post-stress and rest functional parameters, as measured by gated-SPECT, provide additional predictive value for long-term prognosis, over clinical and perfusion data in patients (pts.) with low left ventricular ejection fraction (LVEF). METHODS:647 consecutive pts. underwent stress/rest gated-SPECT, and 497 were followed for a mean period of 516 +/- 264 days. Segmental perfusion and motion/thickening (post-stress and rest) were analysed visually, while EF and LV volumes were calculated using an automatic algorithm (QGS). The post-stress and rest ratio were determined for both end-diastolic (EDV) and end-systolic volume (ESV), while the post-stress LVEF change was calculated subtracting rest-EF from stress-EF. RESULTS:84/497 pts. showed rest EF < 40%, and 15/84 (18%) experienced a cardiac event (3 cardiac deaths, 1 infarction, 3 hospitalized angina and 9 late revascularizations). The perfusion and functional parameters were not significantly more compromised in pts. with cardiac events compared with pts. without events. Post-stress ESV was the only index significantly higher in pts. with low EF and events compared with pts. with low EF without events (150 +/- 72 ml vs. 123 +/- 53 ml, P = 0.02). Univariate Cox analysis of clinical, perfusion and functional data showed that the best predictor of cardiac events was stress-ESV (score 6.5, P = 0.01), followed by rest-ESV, rest-EDV, stress-EDV and stress-LVEF. Multivariate analysis demonstrated that the addition of stress-ESV to stress-EF, yielded a significant increase in the global chi2 in the prediction of hard events (cardiac death/infarction) (score 4.634, P = 0.03). CONCLUSION:In patients with depressed LVEF, stress-ESV was the only independent predictor of long-term outcome.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Bestetti A,Triulzi A,Di Leo C,Tagliabue L,Strinchini A,Bax Jdoi
10.2143/AC.59.1.2005154subject
Has Abstractpub_date
2004-02-01 00:00:00pages
17-23issue
1eissn
0001-5385issn
1784-973Xjournal_volume
59pub_type
临床试验,杂志文章abstract:BACKGROUND:There are few studies detailing the prevalence of prehypertension and hypertension in India. METHODS:Men and women, over 25 years of age were included. After completion of a dietitian-administered questionnaire followed evaluation by a physician, physical examination and blood pressure measurement. Cross-se...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究
doi:10.1080/ac.66.1.2064964
更新日期:2011-02-01 00:00:00
abstract::Atrial bigeminy is a supraventricular arrhythmia rarely associated with severe symptoms. We report the case of a 22-year-old woman with no prior cardiac disease presenting with exercise intolerance since several months. No apparent heart disease other than a spontaneous conducted atrial bigeminy with a short coupling ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.4.2126602
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:Elevated mean platelet volume predicts restenosis after percutaneous transluminal coronary angioplasty but its effect on the development of in-stent restenosis is not known. We assessed the effect of mean platelet volume measured before coronary stent implantation for stable angina pectoris on subsequent deve...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.4.2005204
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:Cardiac computed tomography (CT) and conventional biplane ventriculography are established methods for the determination of ventricular function. Recently dual source CT was introduced for cardiac CT scanning providing a temporal resolution of 83 ms independent of the patient's heart rate. The purpose of this...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.3.2038015
更新日期:2009-06-01 00:00:00
abstract::Background: This study aimed to examine the value of prognostic nutritional index (PNI) as a predictor of outcomes in patients with heart failure and preserved ejection fraction (HFpEF).Methods: We prospectively followed consecutive adult patients admitted to the cardiology outpatient units with HFPEF. Echocardiograph...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1661139
更新日期:2020-09-01 00:00:00
abstract::Introduction Strength exercises influence the cardiovascular system by promoting autonomic adjustments induced by the increased metabolic demand and consequent increase in local blood flow. However, it is unclear whether there are differences between upper and lower limbs. We aimedto evaluate recovery of cardiac auton...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1335454
更新日期:2017-08-01 00:00:00
abstract::Non invasive blood pressure monitoring using an automatic Nippon Colin recorder was performed in 20 hospitalized hypertensive patients every 15 min during a 4-day study period. A chronobiologic analysis of the data was performed in order to test the consistency of the whole-day blood pressure pattern. Halberg's method...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:Pseudoxanthoma elasticum (PXE) is an autosomal recessive disorder, characterized by extensive mineralization of connective tissues and fragmentation of elastin fibres. PXE patients may sporadically suffer from severe cardiovascular complications caused by accelerated atherosclerosis. Consistent with this find...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.6.1000012
更新日期:2014-12-01 00:00:00
abstract::Creatine kinase (CK) and its isoenzyme CK-MB are important tools for the diagnosis of acute myocardial infarction. The content of CK-MB relative to total CK in myocardial cells is variable; it is low in normal myocardium and increased several-fold in hypoxic myocardium. We tested the hypothesis that CK-MB mass (CK-MBm...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.3.2160721
更新日期:2012-06-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.3.2005008
更新日期:2005-06-01 00:00:00
abstract::Noninvasive diagnosis of cardiac rejection before the advent of myocyte necrosis is important in clinical management of cardiac transplantation. Mice with abdominal heart transplants were studied to determine whether a dual scintigraphy using antimyosin and anti-major histocompatibility complex (MHC) class II antigen ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::Laser displacement technique is a new method to registrate the low frequency precordial movements. In 16 young healthy men the apexcardiograms were obtained subsequently by conventional way and by laser displacement technique. The basic differences in time intervals and amplitude relations were analyzed with paired t-...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Congenital left ventricular diverticulum is rare and usually isolated or associated with midline thoracoabdominal defects and other congenital cardiac malformations. We describe a case with a previously undescribed malformation syndrome including bilateral obstruction of the ureteropelvic junction, agenesis of corpus ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.58.3.2005280
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:Due to uncertainty in the clinical implications of slow coronary flow (SCF), we aimed to investigate the clinical features and mid-term outcome of the Iranian patients with the slow coronary flow phenomenon. METHODS:During a four-year period from January 2005 to December 2009, out of 3523 consecutive patient...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.67.5.2174134
更新日期:2012-10-01 00:00:00
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journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1766259
更新日期:2020-07-03 00:00:00
abstract::A follow-up study was carried out in 98 patients with congestive cardiomyopathy using clinical data and M-mode echocardiography. 59 patients survived (mean follow-up period 18 months), 39 patients died (mean survival period 12.6 months). Median survival time was 3 years. Prognosis was unfavorably affected by ECG signs...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::A definitive diagnosis in patients with syncope is often problematic if the cause is not evident after initial clinical assessment. The cause of syncope may be not established due to the infrequent, episodic occurrence. A symptom-rhythm correlation is frequently an unattainable gold standard in many patients. The impl...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:This study sought to evaluate the potential prognostic usefulness of QT dispersion (QTd) in patients with unstable angina. METHODS AND RESULTS:QTd was calculated and plasma troponin T (TnT) level was measured and rest perfusion imaging with Tc-99m sestamibi was performed in 62 patients admitted with chest pa...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.3.2005183
更新日期:2004-06-01 00:00:00
abstract::The Cardiology Foundation supported by the perspicacious Princess Lilian was created in 1958. As an introduction to this symposium, the challenges that the cardiologist and surgeon encountered in 1958, are recalled as well as the essential problems requiring solutions in that era of evolving cardiac surgery. ...
journal_title:Acta cardiologica
pub_type: 历史文章,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::A 57-year-old woman suffering from severe Prinzmetal's angina was treated with a 7-week course of enhanced external counterpulsation (EECP). After completing EECP the angina intensity was reduced from CCS class IV to class I, quality of life was increased and medication was significantly reduced. The number of hospita...
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doi:10.2143/AC.65.2.2047066
更新日期:2010-04-01 00:00:00
abstract::Most decision-support systems in medicine have been developed in hospital environments, but only few are designed for being used by general practitioners. The present work aims to design an expert system for practitioners in chronic heart failure (CHF) treatment. It provides assistance in defining the therapy relying ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:Acute cardiac allograft rejection continues to be the cause of graft loss and contributes to the morbidity and mortality after cardiac transplantation. Repetitive endomyocardial biopsies are necessary to monitor the effects of immunosuppressants after cardiac transplantation. In this study, we investigate whe...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.6.2136963
更新日期:2011-12-01 00:00:00
abstract:AIM:To determine whether statin therapy initiated early in acute myocardial infarction together with thrombolytic therapy in patients with acute myocardial infarction results in clinical benefit through early plaque stabilization. METHODS AND RESULTS:The study population consisted of 77 patients who underwent coronary...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2143/AC.57.4.2005430
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:Despite the availability of guidelines for preoperative cardiology consultations, their efficacy in real clinical practice remains unknown. Furthermore, there are concerns that overused cardiology consultations can lead to unnecessary investigations, prolonged hospital stays, and even cancellation of necessa...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.66.4.2126592
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:Biodegradable polymer drug-eluting stents may improve biocompatibility and reduce the risk of very late stent thrombosis (ST) but outcomes are nevertheless unknown in diabetic patients. The purpose of this study was to assess the long-term efficacy and safety of the biodegradable polymer biolimus A9-eluting s...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.5.3044879
更新日期:2014-10-01 00:00:00
abstract:OBJECTIVE:Cigarette smoking increases the synthesis of angiotensin-1 converting enzyme (ACE) and induces oxidative modifications of the apolipoprotein E (apo E).Thus we explored the gene-environment interactions between APOE gene epsilon and ACE gene insertion/deletion polymorphisms and cigarette smoking in coronary ar...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.63.6.2033392
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Cardiac rehabilitation for ischaemic heart disease effectively reduces cardiovascular readmission rate and mortality. Current uptake rates however, remain low. This study assesses the social and economic impact of increasing centre-based cardiac rehabilitation uptake and the additional value of cardiac teler...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2017.1361892
更新日期:2018-06-01 00:00:00
abstract::Enalapril is a new angiotensin converting enzyme inhibitor which, when absorbed by the digestive tract, is converted to enalaprilat. This metabolite is, in fact, the active form of enalapril. Its duration of action is sufficiently long so that enalapril can be administered in a single daily dose. Enalapril has been pr...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:
更新日期:1986-01-01 00:00:00
abstract:AIM:The aim of this paper is to study the degree of subclinical arterial wall damage in subjects at low and moderate risk of cardiovascular death by the SCORE scale using instrumental research methods. METHODS:We enrolled 600 patients (mean age 49.0 +/- 7.1 years, 74% women) with a calculated SCORE 5%, who passed a ca...
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pub_type: 杂志文章
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更新日期:2015-06-01 00:00:00