Potential significance of genomic imprinting defects for reproduction and assisted reproductive technology.

abstract：BACKGROUND:Every year 30% of individuals above age 65 fall, and falls are the principal cause of bone fractures. To reduce fracture incidence requires both prevention of falls and maintenance of bone strength. METHODS:PubMed searches were performed, for studies of the epidemiology of fractures, bone physiology, endocr...

journal_title：Human reproduction update

authors： ESHRE Capri Workshop Group.

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The effect of postmenopausal hormone therapy (HT) on cardiovascular disease (CVD) risk remains controversial. OBJECTIVE AND RATIONALE:We aimed to systematically review the evidence regarding the role of dose, route of hormone administration, timing of initiation and duration of HT on cardiovascular risk amo...

journal_title：Human reproduction update

authors： Oliver-Williams C,Glisic M,Shahzad S,Brown E,Pellegrino Baena C,Chadni M,Chowdhury R,Franco OH,Muka T

更新日期：2019-03-01 00:00:00

abstract：:Malnutrition is a major problem in developing countries, and obesity and eating disorders are increasingly common in developing as well as developed countries. The reproductive axis is closely linked to nutritional status, especially undernutrition in the female, and inhibitory pathways involving detectors in the hind...

journal_title：Human reproduction update

authors： ESHRE Capri Workshop Group.

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The drug research and development (R&D) for endometriosis/adenomyosis has been painfully slow. Most completed clinical trials on endometriosis did not publish their results, and presumably failed. While few published trials did report how they foundered, the reasons why they failed are often completely uncle...

journal_title：Human reproduction update

authors： Guo SW,Groothuis PG

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:High-density lipoprotein (HDL) appears to be the dominant lipoprotein particle in human follicular fluid (FF). The reported anti-atherogenic properties of HDL have been attributed in part to reverse cholesterol transport. The discoveries of the scavenger receptor class B type I (SR-BI) and the ATP-binding ca...

journal_title：Human reproduction update

authors： Fujimoto VY,Kane JP,Ishida BY,Bloom MS,Browne RW

更新日期：2010-01-01 00:00:00

abstract：:Protamines are the major nuclear sperm proteins. The human sperm nucleus contains two types of protamine: protamine 1 (P1) encoded by a single-copy gene and the family of protamine 2 (P2) proteins (P2, P3 and P4), all also encoded by a single gene that is transcribed and translated into a precursor protein. The protam...

journal_title：Human reproduction update

authors： Oliva R

更新日期：2006-07-01 00:00:00

abstract：:Cryopreservation of testicular tissue might benefit prepubertal boys who must undergo chemotherapy or radiotherapy. Cryopreservation of testicular tissue and testicular cells for intracytoplasmic sperm injection (ICSI) is feasible and widely applied. Testicular tissue from prepubertal boys can also be frozen, by apply...

journal_title：Human reproduction update

authors： Hovatta O

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Androgens, FSH, anti-Müllerian hormone (AMH) and estradiol (E2) are essential in human ovarian folliculogenesis. However, the interactions between these four players is not fully understood. OBJECTIVES AND RATIONALE:The purpose of this review is to highlight the chronological sequence of the appearance and ...

journal_title：Human reproduction update

authors： Dewailly D,Robin G,Peigne M,Decanter C,Pigny P,Catteau-Jonard S

更新日期：2016-11-01 00:00:00

abstract：:BACKGROUND Angiogenesis, i.e. the development of new blood vessels from pre-existing ones, represents an integral part in the pathogenesis of endometriosis. During the last decade, an increasing number of studies have therefore focused on the anti-angiogenic treatment of the disease. The present review provides a syst...

journal_title：Human reproduction update

authors： Laschke MW,Menger MD

更新日期：2012-11-01 00:00:00

abstract：:Hormonal contraception has become more effective and more widely used, while the world population has grown from 3000 million in 1960 to 6000 million in 2000. There is a need for improved contraception, because legal abortion is used in a high proportion of pregnancies and illegal abortion continues to be common in so...

journal_title：Human reproduction update

authors：

更新日期：2002-07-01 00:00:00

abstract：:The improved long-term survival of adolescents and young women treated for cancer has resulted in an increased focus on the effects of chemotherapy on ovarian function and its preservation. These women may seek advice and treatment regarding their reproductive status, including ways of preserving their fertility and p...

journal_title：Human reproduction update

authors： Lutchman Singh K,Davies M,Chatterjee R

更新日期：2005-01-01 00:00:00

abstract：:As soon as leptin was discovered four years ago, its potential as a player in the polycystic ovary syndrome (PCOS) was explored in a primitive way, though little light was shed on the enigma that is PCOS. As a second wave of leptin research is now available, we review how the expanded role of the cytokine in reproduct...

journal_title：Human reproduction update

authors： Jacobs HS,Conway GS

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Endometriosis is recognized as a steroid-dependent disorder; however, the precise roles of nuclear receptors (NRs) in steroid responsiveness and other signaling pathways are not well understood. OBJECTIVE AND RATIONALE:Over the past several years, a number of paradigm-shifting breakthroughs have occurred in...

journal_title：Human reproduction update

authors： Yilmaz BD,Bulun SE

更新日期：2019-07-01 00:00:00

abstract：:Sperm transport from the cervix into the tube is an important uterine function within the process of reproduction. This function is exerted by uterine peristalsis and is controlled by the dominant ovarian structure via a cascade of endocrine events. The uterine peristaltic activity involves only the stratum subvascula...

journal_title：Human reproduction update

authors： Kunz G,Herbertz M,Noe M,Leyendecker G

更新日期：1998-09-01 00:00:00

abstract：:In 1987, Nigel Harris cautioned against over-diagnosing the antiphospholipid syndrome (APS). In what was a rather prophetic editorial titled 'The Syndrome of the Black Swan', he suggested that while patients with APS do indeed exist, they are probably much more unusual than many medical professionals might like to bel...

journal_title：Human reproduction update

authors： Clark CA,Laskin CA,Spitzer KA

更新日期：2012-09-01 00:00:00

abstract：:Single-dose and multiple-rising dose studies of recombinant follicle stimulating hormone (rFSH) in hypogonadotrophic male and female volunteers demonstrated that the rate of FSH absorption after i.m. injection is higher in men than in women. In the absence of endogenous FSH, a correlation between serum FSH and body we...

journal_title：Human reproduction update

authors： Mannaerts BM,Rombout F,Out HJ,Coelingh Bennink H

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:The aim of this meta-analysis was to investigate whether any difference exists in success rate of clinical outcomes of assisted reproductive technologies (ART) between women who actively smoke cigarettes at the time of treatment and those who do not. METHODS:An intensive computerized search was conducted on...

journal_title：Human reproduction update

authors： Waylen AL,Metwally M,Jones GL,Wilkinson AJ,Ledger WL

更新日期：2009-01-01 00:00:00

abstract：:Conservative management of at least part of both the ovary and uterus can be proposed in patients with borderline ovarian tumour, in order to preserve fertility potential. This conservative management could be carried out even in patients with borderline ovarian tumour associated with non-invasive peritoneal implants ...

journal_title：Human reproduction update

authors： Morice P,Camatte S,Wicart-Poque F,Atallah D,Rouzier R,Pautier P,Pomel C,Lhommé C,Duvillard P,Castaigne D

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:The reproductive impact of adenomyosis and endometriosis is widely researched but the extent of these impacts remains elusive. It has been demonstrated that endometriosis, in particular, is known to result in subfertility but endometriosis and adenomyosis are increasingly linked to late pregnancy complicatio...

journal_title：Human reproduction update

authors： Horton J,Sterrenburg M,Lane S,Maheshwari A,Li TC,Cheong Y

更新日期：2019-09-11 00:00:00

abstract：:Mucin glycoproteins are major constituents of the glycocalyx that covers mucosal epithelium. Two broad classes of mucins exist: membrane-associated and secretory. Of the secreted mucins, those with cysteine-rich regions are thought to polymerize through disulphide bonds. Among these gel-forming mucins are MUC2, MUC5AC...

journal_title：Human reproduction update

authors： Lagow E,DeSouza MM,Carson DD

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Induced abortion is a common procedure. However, there is marked variation in accessibility of services across England. Accessing abortion services may be difficult, particularly for women who live in remote areas, are in the second trimester of pregnancy, have complex pre-existing conditions or have difficu...

journal_title：Human reproduction update

authors： O'Shea LE,Hawkins JE,Lord J,Schmidt-Hansen M,Hasler E,Cameron S,Cameron IT

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Infertility affects ∼7% of all men. Despite much progress, mainly in genetics, its etiology remains obscure in ∼50% of cases. To fill this gap, imaging of the male genital tract (MGT) has progressively expanded, providing useful information in the assessment of MGT abnormalities. METHODS:A critical, systema...

journal_title：Human reproduction update

authors： Lotti F,Maggi M

更新日期：2015-01-01 00:00:00

abstract：:The effects on reproductive tract development in male rats, of neonatal exposure to potent (reference) oestrogens, diethylstilboestrol (DES) and ethinyl oestradiol (EE), with those of two environmental oestrogens, octylphenol and hisphenol A were systematically compared. Other treatments, such as administration of a g...

journal_title：Human reproduction update

authors： Williams K,McKinnell C,Saunders PT,Walker M,Fisher JS,Turner KJ,Atanassova N,Sharpe M

更新日期：2001-05-01 00:00:00

abstract：:Apoptosis is a selective process for deletion of cells in various biological systems. This event, similar to proliferation, is tightly regulated, with both processes playing essential roles in the homeostasis of renewable tissues. In human endometrium, proliferation and apoptosis occur at opposing poles of the menstru...

journal_title：Human reproduction update

authors： Tabibzadeh S

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Worldwide, placenta-related complications contribute to adverse pregnancy outcomes, such as pre-eclampsia, fetal growth restriction and preterm birth, with implications for the future health of mothers and offspring. The placenta develops in the periconception period and forms the interface between mother an...

journal_title：Human reproduction update

authors： Reijnders IF,Mulders AGMGJ,van der Windt M,Steegers EAP,Steegers-Theunissen RPM

更新日期：2019-01-01 00:00:00

abstract：:Nitric oxide (NO) is an important mediator of paracrine interactions, especially within the vascular system. It is a powerful inhibitor of platelet aggregation and a potent vasodilator. NO is also a neurotransmitter and it plays a role in cell-mediated cytotoxicity. NO-generating enzymes (nitric oxide synthases, NOS) ...

journal_title：Human reproduction update

authors： Cameron IT,Campbell S

更新日期：1998-09-01 00:00:00

abstract：:This review provides an overview of how women adjust emotionally to the various phases of IVF treatment in terms of anxiety, depression or general distress before, during and after different treatment cycles. A systematic scrutiny of the literature yielded 706 articles that paid attention to emotional aspects of IVF t...

journal_title：Human reproduction update

authors： Verhaak CM,Smeenk JM,Evers AW,Kremer JA,Kraaimaat FW,Braat DD

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Important roles for G-protein-coupled receptors (GPCRs) have been identified in the maternal physiological adaptations to pregnancy and in the pathogenesis of preeclampsia. On this basis, GPCRs are potential therapeutic targets for preeclampsia. OBJECTIVES AND RATIONALE:In this review, vasopressin and apeli...

journal_title：Human reproduction update

authors： Conrad KP

更新日期：2016-09-01 00:00:00

abstract：:The use of laparoscopic techniques for the treatment of polycystic ovarian syndrome (PCOS) has included many different approaches in the 1980s and 90s. Broadly similiar results have been obtained using biopsy, cauterization, multi-electrocoagulation and laser surgery; i.e. > 50% ovulation and a mean pregnancy rate of ...

journal_title：Human reproduction update

authors： Cohen J

更新日期：1996-07-01 00:00:00

abstract：:This review addresses research on gamete donors, recipients, and offspring and demonstrates that the foci on all three within the triad are largely directed at disclosure or anonymity; and each in turn centers on the perceived importance of the genetic link. The importance attached to genetics has led some countries t...

journal_title：Human reproduction update

authors： van den Akker O

更新日期：2006-03-01 00:00:00