Abstract:
:When hot-water extracts of mushroom Agaricus brazei MURRILL fruiting bodies (Agaricus extracts) were administered orally into Meth A-bearing mice, tumor growth was significantly inhibited compared with controls given water orally. Treatment with Agaricus extracts for five successive days significantly increased natural killer activity of spleen cells in naïve BALB/c mice. In Meth A-bearing BALB/c mice, Agaricus extracts enhanced the induction of antigen-specific cytotoxic T lymphocytes and interferon gamma production, indicating that Agaricus extracts potentiate cytotoxic activity in innate and adaptive immunity.
journal_name
Biol Pharm Bulljournal_title
Biological & pharmaceutical bulletinauthors
Takimoto H,Wakita D,Kawaguchi K,Kumazawa Ydoi
10.1248/bpb.27.404subject
Has Abstractpub_date
2004-03-01 00:00:00pages
404-6issue
3eissn
0918-6158issn
1347-5215journal_volume
27pub_type
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