Occupational exposures to acid mists and gases and ulcerative lesions of the oral mucosa.

Abstract:

BACKGROUND:This study examines the hypothesis that acid mist or mixtures of acid mists and acid gases are associated with ulcerative lesions of the oral mucosa. METHODS:All 665 active male workers of a metal processing factory were the study population. Semi-quantitative measures of exposure were estimated from a job exposure matrix constructed with industrial hygienist scoring and job titles. Ulcerative lesions of the oral mucosa were identified with standardized clinical dental exams. RESULTS:Past exposure to acid mists were positively associated with ulcerative lesions of the oral mucosa but only among workers without lip sealing (age- and alcohol consumption-adjusted prevalence ratio (PR), PR(adjusted) = 3.40; 90% CI: 1.48-7.85). Also in this worker group, the mixture of acid mists and acid gases was associated with ulcerative lesions of the oral mucosa limited to exposure in the past (PR(adjusted) = 2.83; 90% CI: 1.12-7.17). CONCLUSIONS:There is a positive association between acid mist or mixtures of acid mists and acid gases and ulcerative lesions of the oral mucosa only in the absence of lip sealing. The evidence of a chronic rather than acute irritative process suggests a possible step on the etiology of oral malignancies, which needs investigation.

journal_name

Am J Ind Med

authors

Vianna MI,Santana VS,Loomis D

doi

10.1002/ajim.10343

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

238-45

issue

3

eissn

0271-3586

issn

1097-0274

journal_volume

45

pub_type

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