Stereotactic MR imaging for planning neural transplantation: a reliable technique at 3 Tesla?

Abstract:

:The purpose of this study was to assess the accuracy of high field (3 Tesla) MR in target localization for stem cell transplantation. Three patients with Huntington's disease were imaged with a stereotactic frame in place for both MRI and CT. Quality assurance procedures and manual shimming were performed before each MRI study to minimize image distortion. The images were fused using multi-modality rigid body image registration software. Image fusion demonstrated the MR images to be in agreement with CT to within 1.5 mm, as assessed by measuring the coordinates of markers on the frame and on the shape and size of the lateral ventricles. Target coordinates for transplantation were selected from the MR images. Postoperative imaging confirmed accurate graft placement.

journal_name

Br J Neurosurg

authors

Donovan T,Fryer TD,Peña A,Watts C,Carpenter TA,Pickard JD

doi

10.1080/02688690310001613844

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

443-9

issue

5

eissn

0268-8697

issn

1360-046X

journal_volume

17

pub_type

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