Abstract:
:We investigated the cardiotoxic effects of 1,1,2-Trichloro-1,2,2- Trifluoroethane (fluorocarbon 113 or FC113) exposures among healthy workers cleaning rocket and ground support equipment for the National Aeronautic and Space Administration (NASA) programs. Exposure and ambulatory electrocardiographic (ECG) monitoring data were evaluated on 16 workers, each of whom was examined on exposed and nonexposed workdays. We examined whether there was a greater rate of dysrhythmias on an exposed workday relative to a nonexposed workday. Overall, we found no within subject differences in the rate of ventricular and supraventricular premature beats (number per 1,000 heart beats), fluctuations in the length of the P-R interval, or heart rate. We found that levels of FC113 exposures below the Occupational Safety and Health Administration (OSHA) 8-hour time-weighted-average (TWA) standard of 1,000 ppm did not induce cardiac dysrhythmias or subtle changes in cardiac activity. However, because fluorocarbons may sensitize the heart to epinephrine, this study's negative findings based on sedentary and fairly healthy workers may not be generalizable to other populations of workers who are not as healthy or engaged in more physically demanding work.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Egeland GM,Bloom TF,Schnorr TM,Hornung RW,Suruda AJ,Wille KKdoi
10.1002/ajim.4700220607subject
Has Abstractpub_date
1992-01-01 00:00:00pages
851-7issue
6eissn
0271-3586issn
1097-0274journal_volume
22pub_type
杂志文章abstract::Several studies on the mortality of chemists have revealed a lower overall mortality but an excess of deaths from certain diseases, in particular, cancers. This study determined the causes of mortality of 4,012 chemists among 14,884 members of The Royal Society of Chemistry who were followed for a period of 25 years. ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230409
更新日期:1993-04-01 00:00:00
abstract::Exposure to grain dust has been associated with a neutrophilic bronchitis. In vitro studies suggest several possible mechanisms for recruitment of neutrophils, including direct chemotaxis to aqueous grain dust extracts and release of chemotactic activity by bronchial epithelial cells in response to challenge with grai...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250122
更新日期:1994-01-01 00:00:00
abstract::A study of 67 subjects in a small titanium oxide paint factory in Nigeria showed 50-54% frequency for airway symptoms, 20-40% for neurological symptoms, and 10-27% for other symptoms. The symptoms were well correlated with exposure (p less than .05) and pulmonary function tests (PFTs). The directly exposed subjects ha...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120206
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Falls are the leading cause of fatalities in construction. The Safety Pays, Falls Cost campaign aims to prevent falls in residential construction. A critical component of our social marketing approach was to involve 70 partners in reaching target audiences. METHODS:We assessed partner engagement April 2012-...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22458
更新日期:2015-08-01 00:00:00
abstract::In order to determine the possible actual exposure to benzene in the shoe industry from industrially used solvents, glues, and paints containing benzene as a nondeclared constituent, phenol in urine and benzene in blood, as indices of internal exposure to benzene, were measured in workers (N = 33). Since toluene, in c...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700120507
更新日期:1987-01-01 00:00:00
abstract::The reproductive toxicology of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has been studied in animal models and in human populations. In animals, TCDD has a range of toxic effects on organs of the reproductive system in males and females, on hormone biochemistry, and on embryo-fetal development. These effects may invo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700110203
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:The purpose of Pre-Adult Latency Study was to evaluate lung findings among adults who had been environmentally exposed to Libby Amphibole only during childhood and adolescence. METHODS:Recruitment was restricted to volunteers who attended primary and/or secondary school, lived in Libby, MT, prior to age 23 ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22674
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:A series of illnesses occurred in Earlimart, CA on November 13, 1999 following a metam-sodium sprinkler application to a potato field on the southern edge of the town. METHODS:Case information was obtained from direct interviews, from illness complaints filed with state or county agencies, or from illness r...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20037
更新日期:2004-07-01 00:00:00
abstract:BACKGROUND:Hospital workers are a diverse population with high rates of musculoskeletal disorders (MSDs). The risk of MSD leading to workers' compensation (WC) claims is likely to show a gradient by socioeconomic status (SES) that may be partly explained by working conditions. METHODS:A single community hospital provi...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20702
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the association between dynamic thiol/disulphide homeostasis and occupational exposure to volatile anesthetic gases in operating theater personnel. Decreased blood thiol levels and raised blood disulphide levels serve as biomarkers of oxidative stress. METHODS:We...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22764
更新日期:2017-11-01 00:00:00
abstract::Eight healthy volunteers were exposed to purified lipopolysaccharide (LPS) by controlled inhalation. Bronchoalveolar lavage (BAL) 3 hours after exposure revealed a pronounced neutrophilia, increase in lymphocytes, fibronectin concentration, and decrease in alveolar macrophage phagocytosis, as compared to a reference B...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700250127
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Small retail businesses experience high robbery and violent crime rates leading to injury and death. Workplace violence prevention programs (WVPP) based on Crime Prevention Through Environmental Design reduce this risk, but low small business participation limits their effectiveness. Recent dissemination mod...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22436
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Thoroughbred horse farm workers self-report a high frequency of work-related injuries and pain. However, an analysis of Thoroughbred horse farm workers' compensation injury claims is absent from the literature, yet may benefit worker safety. METHODS:We analyzed workers' compensation insurance firm data cont...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23159
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:As the sustainability of the agricultural workforce has been threatened by the high prevalence of back pain, developing effective interventions to reduce its burden within farming will contribute to the long-term health and productivity of workers. Passive back-support exoskeletons are being explored as an i...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23180
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Occupational cancer monitoring is important for cancer prevention and public health protection. A surveillance system for identifying occupational cancer risks and cancer cases in Italy that are likely to be of occupational origin using information available in the Italian Social Security archives was create...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20356
更新日期:2006-09-01 00:00:00
abstract::Injury is the leading cause of death in adolescence, with the highest rates for 15- to 19-year-olds, an age span also marked, for many, by entry into the workforce. Occupational injuries affecting youth occur in the context of the larger problem of injury affecting children and adolescents. An understanding of the bro...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700240307
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Migrant and seasonal farmworkers are at risk for occupational illnesses from pesticide exposure, and the effectiveness of pesticide safety regulations has not been evaluated. It is important to learn from farmworker safety experiences to develop effective measures to improve agricultural workplace safety. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1042
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Sickness benefit claims are an important economic burden to society. This study aims to determine the incidence of sickness benefit claims in Brazil in 2008, exploring the role of economic activity. METHODS:Population-based study on sickness claims lasting longer than 15 days of sickness absence granted to ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20974
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:A number of employees at an aircraft factory were accidentally exposed to hydrogen sulfide. Because of concern that this may have resulted in lung injury, forty-seven workers were referred for clinical and physiological evaluation. METHODS:Comprehensive pulmonary function tests were performed including spir...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0274(200003)37:3<296::aid-ajim8
更新日期:2000-03-01 00:00:00
abstract::An analysis of reported birth record variables by parental occupation suggests that certain birth outcomes may identify toxic or carcinogenic occupational exposures of the parents. Fathers coded to an asbestos and insulation worker rubric sired fewer plural births, and more stillbirths than expected. A number of other...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700160214
更新日期:1989-01-01 00:00:00
abstract::Mortality and cancer incidence was investigated among 2,807 workers, employed for at least one year before 1972, at 11 Swedish companies manufacturing prefabricated wooden houses. A total of 1,068 workers had been exposed to man-made mineral fibers (MMMF) used for insulation. Mortality was followed from 1969 to 1988 a...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700210605
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Previous epidemiological studies investigating modification of organophosphate (OP) neurotoxicity by xenobiotic metabolizing enzymes (XMEs) polymorphisms have produced inconsistent results. METHODS:A cross-sectional study of 301 emerging farmers was conducted. Neurotoxicity testing included forward and back...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22790
更新日期:2018-01-01 00:00:00
abstract:Background:Little research has addressed the safety environment of child farmworkers. This analysis examines the work safety culture experienced by Latinx child farmworkers in North Carolina. Methods:Survey interviews were conducted in 2017 with 202 Latinx children aged 10 to 17 years employed on North Carolina farms....
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23161
更新日期:2020-10-01 00:00:00
abstract::Multiphasic health testing was provided to 744 rubber workers at a tire manufacturing plant. Sixty-two white males from this population had worked longest in the curing department. Personal exposure to respirable particulates was measured for curing press operators. Outcome on screening tests for curing workers was co...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700020208
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Occupational exposures may be related to the development of brain cancer. The objective was to estimate occupational-specific risk of gliomas and meningiomas among Swedish men and women gainfully employed in 1970 over the period 1971-1989, and the influence of occupational exposure to chemical substances. M...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.10107
更新日期:2002-09-01 00:00:00
abstract::The methodological choices being made in current worker notification programs are influenced in both obvious and subtle ways by certain ground-breaking notifications carried out during the 1970s and 1980s. A lore has built up concerning these cases. Their names are heavy with implied meaning. As worker notification ga...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700230104
更新日期:1993-01-01 00:00:00
abstract::A model was created to assess occupational exposure to extremely low-frequency magnetic fields (ELF-MF) among semiconductor fabrication-room (fab) workers. This model was based on the assumption that each subject's exposure arose from being near identifiable ELF-MF sources or being in areas with high ELF-MF levels. To...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280608
更新日期:1995-12-01 00:00:00
abstract::Currently available computerized hospital records from four hospitals in Southwest Oregon were utilized for occupational health surveillance by administering brief occupational questionnaires to hospitalized male patients. Patients with occupational exposure to the lumber and wood products industries showed statistica...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700040605
更新日期:1983-01-01 00:00:00
abstract::The present report completes a previous study made on three chloralkali plants that was presented at the 8th International Conference on Occupational Health in the Chemical Industry, Tokyo, 1980, with the final results from five plants located in various regions of Italy. A total of 14,339 measurements of mercury in a...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700030308
更新日期:1982-01-01 00:00:00
abstract::Surveillance of cause-specific mortality patterns by occupation and industry through the use of death certificate records is a simple and relatively inexpensive approach to the generation of leads as to potential occupational disease problems. Researchers from the National Institute for Occupational Safety and Health ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.4700110309
更新日期:1987-01-01 00:00:00